المؤلفون: Robert Freund, Dorte B. Bekker-Jensen, Goda Snieckute, Simon Bekker-Jensen, Christopher Tiedje, Jesper V. Olsen, Alexey Kotlyarov, Martin R Turner, Matthias Gaestel, Manoj B. Menon, Manuel D. Díaz-Muñoz, Philipp Trulley

المصدر: Cell Reports, Vol 27, Iss 10, Pp 2859-2870.e6 (2019)
Trulley, P, Snieckute, G, Bekker-Jensen, D, Menon, M B, Freund, R, Kotlyarov, A, Olsen, J V, Diaz-Muñoz, M D, Turner, M, Bekker-Jensen, S, Gaestel, M & Tiedje, C 2019, ' Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2 ', Cell Reports, vol. 27, no. 10, pp. 2859-2870.e6 . https://doi.org/10.1016/j.celrep.2019.05.024Test

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Untranslated region, Five prime untranslated region, MAP Kinase Signaling System, Protein Serine-Threonine Kinases, p38 Mitogen-Activated Protein Kinases, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Eukaryotic translation, Animals, Humans, Protein Isoforms, RNA, Messenger, Phosphorylation, RNA, Small Interfering, Protein kinase A, Peptide Chain Initiation, Translational, lcsh:QH301-705.5, Heat-Shock Proteins, Regulation of gene expression, Mice, Knockout, Chemistry, Intracellular Signaling Peptides and Proteins, EIF4A1, RNA Helicase A, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, RAW 264.7 Cells, Gene Expression Regulation, lcsh:Biology (General), 030217 neurology & neurosurgery, RNA Helicases, Molecular Chaperones

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34582960dd0ab6e715848184a0566225Test
http://www.sciencedirect.com/science/article/pii/S2211124719306357Test

المؤلفون: Manuel D. Díaz-Muñoz, Martin R Turner

المصدر: Nature Immunology. 19:120-129

مصطلحات موضوعية: 0301 basic medicine, Immunology, RNA-Binding Proteins, RNA, RNA-binding protein, Cell fate determination, Biology, Cell biology, Transcriptome, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Gene Expression Regulation, Immune System, Proteome, Gene expression, Animals, Humans, Immunology and Allergy, Function (biology), Biogenesis, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc84577e684e94c54b005fab8dce838Test
https://doi.org/10.1038/s41590-017-0028-4Test

المؤلفون: Tomaz Curk, Manuel D. Díaz-Muñoz, Jernej Ule, Vladimir Yu. Kiselev, Nicolas Le Novère, Martin R Turner

المساهمون: Díaz-Muñoz, Manuel D [0000-0002-9227-7474], Kiselev, Vladimir Yu [0000-0003-1893-2255], Le Novère, Nicolas [0000-0002-6309-7327], Curk, Tomaz [0000-0003-4888-7256], Ule, Jernej [0000-0002-2452-4277], Turner, Martin [0000-0002-3801-9896], Apollo - University of Cambridge Repository

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, DNA damage, Science, General Physics and Astronomy, RNA-binding protein, Ataxia Telangiectasia Mutated Proteins, Biology, Lymphocyte Activation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Stress granule, Polysome, P-bodies, Protein biosynthesis, Animals, Humans, RNA, Messenger, lcsh:Science, 3' Untranslated Regions, Etoposide, Messenger RNA, B-Lymphocytes, Multidisciplinary, Three prime untranslated region, General Chemistry, Molecular biology, T-Cell Intracellular Antigen-1, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, Gene Expression Regulation, Protein Biosynthesis, lcsh:Q, Tumor Suppressor Protein p53, 030217 neurology & neurosurgery, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccd3fafcbc4c34712a36953c8e92debTest
https://doaj.org/article/be40aa23daf3428d9a9e7cfc26ff2f38Test

المؤلفون: Simon J. Cook, Sebastian Łukasiak, Alison Galloway, Anne E. Corcoran, Sara Ciullini Mannurita, Manuel D. Díaz-Muñoz, Martin R Turner, Elisa Monzón-Casanova, Kathryn Balmanno, Lewis S. Bell, Alexander Saveliev, Daniel J. Bolland, Helena Ahlfors, Daniel J. Hodson, Simon Andrews

المصدر: Science. 352:453-459

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, B-cell receptor, RNA-binding protein, Biology, Resting Phase, Cell Cycle, S Phase, Mice, 03 medical and health sciences, Tristetraprolin, Cell quiescence, Cyclins, Animals, RNA, Messenger, Selection, Genetic, Gene, Conserved Sequence, S phase, Progenitor, Mice, Knockout, B-Lymphocytes, Multidisciplinary, Immunoglobulin mu-Chains, G1 Phase, Nuclear Proteins, RNA-Binding Proteins, Cell cycle, V(D)J Recombination, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Regulon, Gene Expression Regulation, Pre-B Cell Receptors, Butyrate Response Factor 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38228a10140f71fce09d1f9da2e96e5dTest
https://doi.org/10.1126/science.aad5978Test

المؤلفون: Manuel D, Díaz-Muñoz, Martin, Turner

المصدر: Frontiers in Immunology

مصطلحات موضوعية: Immunity, Cellular, immune cell homeostasis, T-Lymphocytes, T-cell mediated immunity, Immunology, RNA-Binding Proteins, Review, Epigenesis, Genetic, Immunity, Humoral, Gene Expression Regulation, Immune System, immune cell development, Animals, Homeostasis, Humans, Myeloid Cells, RNA binding proteins, immune cell activation, RNA Processing, Post-Transcriptional, post-transcriptional RNA regulation, humoral response

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::3e712cc79cff33cc6d3b3eb419a996dbTest
https://pubmed.ncbi.nlm.nih.gov/29875770Test

المؤلفون: Christopher Tiedje, Kathrin Laaß, Matthias Gaestel, Perry J. Blackshear, Manuel D. Díaz-Muñoz, Helena Ahlfors, Martin R Turner, Philipp Trulley

المساهمون: Turner, Martin [0000-0002-3801-9896], Apollo - University of Cambridge Repository

المصدر: Nucleic Acids Research

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Cell Survival, IER3, Tristetraprolin, RNA-binding protein, Bone Marrow Cells, Biology, Protein Serine-Threonine Kinases, Substrate Specificity, 03 medical and health sciences, Mice, hemic and lymphatic diseases, Gene expression, Genetics, Transcriptional regulation, Protein biosynthesis, ZFP36, Animals, Humans, Immunoprecipitation, heterocyclic compounds, RNA, Messenger, Phosphorylation, neoplasms, Adaptor Proteins, Signal Transducing, Feedback, Physiological, Inflammation, Macrophages, Intracellular Signaling Peptides and Proteins, NF-kappa B, RNA-Binding Proteins, respiratory system, Molecular biology, High-Throughput Screening Assays, 030104 developmental biology, Cross-Linking Reagents, Gene Expression Regulation, Cytokines, RNA, Transcriptome, ICLIP, therapeutics, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78b3c88e46299d628b9220373830340Test
https://pubmed.ncbi.nlm.nih.gov/27220464Test

المؤلفون: Inés Álvarez, Manuel D. Díaz-Muñoz, Jordi Buxens, Rosa Cuberes, Miguel A. Iñiguez, Carmen Punzón, Eva Ma Andres, José Miguel Vela, Cristina Cacheiro-Llaguno, Javier Duque, Helmut Buschmann, Manuel Fresno

المصدر: International Immunopharmacology. 10:1295-1304

مصطلحات موضوعية: T-Lymphocytes, T cell, Immunology, Pharmacology, Lymphocyte Activation, Jurkat cells, Jurkat Cells, Interferon, medicine, Animals, Humans, Immunology and Allergy, Transcription factor, Inflammation, Cyclooxygenase 2 Inhibitors, Molecular Structure, NFATC Transcription Factors, biology, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, NF-kappa B, NFAT, Exudates and Transudates, Rats, medicine.anatomical_structure, Gene Expression Regulation, Eicosanoid, Biochemistry, Gastric Mucosa, biology.protein, Pyrazoles, Tumor necrosis factor alpha, Cyclooxygenase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017fc617a9818c94a4076a442d09ac84Test
https://doi.org/10.1016/j.intimp.2010.07.013Test

المؤلفون: Manuel D. Díaz-Muñoz, Sarah Bell, Martin R Turner

المساهمون: Turner, Martin [0000-0002-3801-9896], Apollo - University of Cambridge Repository

المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0116899 (2015)

مصطلحات موضوعية: Untranslated region, Cell Survival, RNA Stability, ELAV-Like Protein 1, lcsh:Medicine, RNA-binding protein, Biology, Mice, immune system diseases, hemic and lymphatic diseases, Animals, Heterogeneous Nuclear Ribonucleoprotein D0, Heterogeneous-Nuclear Ribonucleoprotein D, lcsh:Science, neoplasms, Sequence Deletion, AU-rich element, Regulation of gene expression, AU Rich Elements, Messenger RNA, B-Lymphocytes, Multidisciplinary, Base Sequence, Three prime untranslated region, lcsh:R, Gene targeting, Molecular biology, Gene Expression Regulation, Proto-Oncogene Proteins c-bcl-2, lcsh:Q, biological phenomena, cell phenomena, and immunity, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ea87e10e4a54b2511fe955539fce16Test
https://www.repository.cam.ac.uk/handle/1810/293909Test