المؤلفون: Himanen, S. V., Puustinen, M. C., Da Silva, A. J., Vihervaara, Anniina, Sistonen, L.

المصدر: Nucleic Acids Research. 50(11):6102-6115

مصطلحات موضوعية: glutathione, heat shock transcription factor, heat shock transcription factor 1, heat shock transcription factor 2, menadione, RNA polymerase II, transcription factor Nrf2, unclassified drug, DNA binding protein, heat shock protein, Article, Cacybp gene, controlled study, differential expression analysis, down regulation, enhancer region, gene, gene activation, gene expression, genetic transcription, heat stress, Hs 578T cell line, human, human cell, immunofluorescence, oxidation reduction state, oxidative stress, promoter region, temperature, transcription initiation, upregulation, Western blotting, genetics, heat shock response, metabolism, DNA-Binding Proteins, Heat Shock Transcription Factors, Heat-Shock Proteins, Heat-Shock Response

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326800Test
https://doi.org/10.1093/nar/gkac493Test

المؤلفون: Kageyama, Shun, Gudmundsson, Sigurdur Runar, Sou, Yu-Shin, Ichimura, Yoshinobu, Tamura, Naoki, Kazuno, Saiko, Ueno, Takashi, Miura, Yoshiki, Noshiro, Daisuke, Abe, Manabu, Mizushima, Tsunehiro, Miura, Nobuaki, Okuda, Shujiro, Motohashi, Hozumi, Lee, Jin-A, Sakimura, Kenji, Ohe, Tomoyuki, Noda, Nobuo N., Waguri, Satoshi, Eskelinen, Eeva-Liisa, Komatsu, Masaaki

المساهمون: Autophagy, Molecular and Integrative Biosciences Research Programme, Biosciences, Biochemistry and Biotechnology

مصطلحات موضوعية: TRANSCRIPTION FACTOR NRF2, ELECTRON-MICROSCOPY, SELECTIVE AUTOPHAGY, STRUCTURAL BASIS, P62, DEGRADATION, RECOGNITION, GENE, MICE, PHOSPHORYLATION, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: We thank all members of Komatsu's lab. and Sanchez-Martin Pablo for their helpful comments and discussion. S. Kageyama is supported by a Grant-in-Aid for Scientific Research (C) (20K06549). Y.-S.S. is supported by a Grant-in-Aid for Scientific Research (C) (19K15043). D.N. is supported by a Grant-in-Aid for Early-Career Scientists (19K16344). N.N.N. is supported by a Grant-in-Aid for Scientific Research on Innovative Areas (19H05707). M.K. is supported by a Grant-in-Aid for Scientific Research on Innovative Areas (19H05706), a Grant-in-Aid for Scientific Research (B) (18H02611), the Japan Society for the Promotion of Science (an A3 foresight program), and the Takeda Science Foundation (to M.K.). This work was supported by JSPS KAKENHI Grant Number JP 16H06276 (AdAMS). E.L.E. and S.R.G. were supported by the Academy of Finland and Magnus Ehrnrooth Foundation. The Electron Microscopy Laboratory at Institute of Biomedicine, University of Turku, in thanked for technical help and availability of instruments.; Kageyama , S , Gudmundsson , S R , Sou , Y-S , Ichimura , Y , Tamura , N , Kazuno , S , Ueno , T , Miura , Y , Noshiro , D , Abe , M , Mizushima , T , Miura , N , Okuda , S , Motohashi , H , Lee , J-A , Sakimura , K , Ohe , T , Noda , N N , Waguri , S , Eskelinen , E-L & Komatsu , M 2021 , ' p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response ' , Nature Communications , vol. 12 , 16 . https://doi.org/10.1038/s41467-020-20185-1Test; ORCID: /0000-0003-0006-7785/work/98374030; 9c0b6341-156f-4765-9355-7442fbddfb9d; http://hdl.handle.net/10138/333044Test; 000665625900013

الإتاحة: http://hdl.handle.net/10138/333044Test

المؤلفون: Ji, Weixiu, Wang, Linjia, He, Shiyi, Yan, Lu, Li, Tieying, Wang, Jianxiong, Kong, Ah-Ng Tony, Yu, Siwang, Zhang, Ying

مصطلحات موضوعية: hypoxia inducible factor 1alpha, small interfering RNA, transcription factor Nrf2, animal cell, antioxidant responsive element, binding affinity, C2C12 cell line, controlled study, disease duration, exposure, gene, gene activation, gene knockdown, hypoxia, male, mouse, nonhuman, protein expression, quadriceps femoris musc le, signal transduction, skeletal muscle, transgenic mouse, upregulation

وصف الملف: application/pdf

العلاقة: https://research.usq.edu.au/download/68b54f1a653161c04b5e841ac4779b9cc4b45877fcca91e45e3fbc89923b6795/2811419/2018-12%20Plos%20one%20Nrf2%20and%20hypoxia.pdfTest; https://doi.org/10.1371/journal.pone.0208474Test; Ji, Weixiu, Wang, Linjia, He, Shiyi, Yan, Lu, Li, Tieying, Wang, Jianxiong, Kong, Ah-Ng Tony, Yu, Siwang and Zhang, Ying. 2018. "Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle." PLoS One. 13 (12), pp. 1-15. https://doi.org/10.1371/journal.pone.0208474Test

الإتاحة: https://doi.org/10.1371/journal.pone.0208474Test
https://research.usq.edu.au/item/q4z8w/effects-of-acute-hypoxia-exposure-with-different-durations-on-activation-ofTest-nrf2-are-pathway-in-mouse-skeletal-muscle
https://research.usq.edu.au/download/68b54f1a653161c04b5e841ac4779b9cc4b45877fcca91e45e3fbc89923b6795/2811419/2018-12%20Plos%20one%20Nrf2%20and%20hypoxia.pdfTest

المؤلفون: Pursani, V, Bhartiya, D, Tanavde, V, Bashir, M, Sampath, P

المساهمون: DEPT OF BIOCHEMISTRY

المصدر: Unpaywall 20201031

مصطلحات موضوعية: histone methyltransferase, histone methyltransferase DOT1L, homeobox protein Nkx-2.5, octamer transcription factor 4, small interfering RNA, transcription factor NANOG, unclassified drug, basic helix loop helix transcription factor, calcium binding protein, DOT1L protein, human, helix-loop-helix protein, eHAND, membrane protein, methyltransferase, muscle protein, MYOF protein, NFE2L2 protein, NKX2-5 protein, transcription factor Nrf2, Article, cardiac cell line, cardiac stem cell, cell activity, cell differentiation, chromatin immunoprecipitation, controlled study, embryo, enzyme localization, gene

العلاقة: Pursani, V, Bhartiya, D, Tanavde, V, Bashir, M, Sampath, P (2018). Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage. Stem Cell Research and Therapy 9 (1) : 97. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-018-0810-8Test; https://scholarbank.nus.edu.sg/handle/10635/178092Test

الإتاحة: https://doi.org/10.1186/s13287-018-0810-8Test
https://scholarbank.nus.edu.sg/handle/10635/178092Test

المؤلفون: Shujiro Okuda, Takashi Ueno, Manabu Abe, Nobuaki Miura, Tsunehiro Mizushima, Naoki Tamura, Masaaki Komatsu, Jin-A Lee, Saiko Kazuno, Yoshinobu Ichimura, Yu-shin Sou, Satoshi Waguri, Eeva-Liisa Eskelinen, Tomoyuki Ohe, Kenji Sakimura, Yoshiki Miura, Sigurdur Runar Gudmundsson, Nobuo N. Noda, Hozumi Motohashi, Daisuke Noshiro, Shun Kageyama

المساهمون: Autophagy, Molecular and Integrative Biosciences Research Programme, Biosciences, Biochemistry and Biotechnology

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Autophagosome, P62, General Physics and Astronomy, TRANSCRIPTION FACTOR NRF2, Plasma protein binding, 0302 clinical medicine, Ubiquitin, Sequestosome-1 Protein, PHOSPHORYLATION, ELECTRON-MICROSCOPY, Kelch-Like ECH-Associated Protein 1, Multidisciplinary, biology, Chemistry, 3. Good health, Cell biology, Liver, Phosphorylation, Microtubule-Associated Proteins, Protein Binding, STRUCTURAL BASIS, NF-E2-Related Factor 2, Science, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Macroautophagy, Autophagy, Animals, Humans, SELECTIVE AUTOPHAGY, Transcription factor, Unilamellar Liposomes, Autophagosomes, RECOGNITION, General Chemistry, DEGRADATION, KEAP1, GENE, Mice, Inbred C57BL, Oxidative Stress, MICE, 030104 developmental biology, Hepatocytes, biology.protein, 1182 Biochemistry, cell and molecular biology, Apoptosis Regulatory Proteins, Lysosomes, Gels, 030217 neurology & neurosurgery, Biogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfb4be4fea4d888a2f39fe826705fd3Test
http://hdl.handle.net/10138/333044Test

المؤلفون: Hu, Q, Khanna, P, Ee Wong, B.S, Heng, Z.S.L, Subhramanyam, C.S, Thanga, L.Z, Tan, S.W.S, Baeg, G.H

المساهمون: ANATOMY, DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20200831

مصطلحات موضوعية: alpha [amino(4 aminophenylthio)methylene] 2 (trifluoromethyl)phenylacetonitrile, antioxidant, mitogen activated protein kinase, mitogen activated protein kinase 1, mitogen activated protein kinase 3, paraquat, reactive oxygen metabolite, transcription factor Nrf2, Article, cell level, cell structure, controlled study, embryo, embryonic stem cell, gene, gene expression, GFRA1 gene, HOXA1 gene, human, human cell, immunocytochemistry, NANOG gene, NCAM gene, nerve cell differentiation, neurite, NEUROD1 gene, OCT4 gene, oxidative stress, PAX6 gene, polymerase chain reaction

العلاقة: Hu, Q, Khanna, P, Ee Wong, B.S, Heng, Z.S.L, Subhramanyam, C.S, Thanga, L.Z, Tan, S.W.S, Baeg, G.H (2018). Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation. Oncotarget 9 (3) : 4223-4238. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.23786Test; https://scholarbank.nus.edu.sg/handle/10635/174366Test

الإتاحة: https://doi.org/10.18632/oncotarget.23786Test
https://scholarbank.nus.edu.sg/handle/10635/174366Test

المؤلفون: Judith M. Vonk, Hendrika Boezen, Sylwia M. Figarska

المساهمون: Life Course Epidemiology (LCE), Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: Physiological Genomics, 46(12), 411-417. AMER PHYSIOLOGICAL SOC
Physiological Genomics

مصطلحات موضوعية: Male, DISRUPTION, FIBROBLASTS, NF-E2-Related Factor 2, Physiology, Cellular detoxification, Population, TRANSCRIPTION FACTOR NRF2, Biology, medicine.disease_cause, Polymorphism, Single Nucleotide, general population, OBSTRUCTIVE PULMONARY-DISEASE, COPD mortality, ACTIVATION, Pulmonary Disease, Chronic Obstructive, Transcription (biology), cardiovascular mortality, LUNG-FUNCTION DECLINE, Genetics, medicine, Humans, Genetic Predisposition to Disease, OXIDATIVE STRESS, education, Gene, Triglycerides, Aged, Netherlands, Proportional Hazards Models, NFE2L2, Aged, 80 and over, education.field_of_study, NF-E2-RELATED FACTOR-2, Metabolism, Middle Aged, General Interest, ENDOTHELIAL-CELLS, 3. Good health, Cholesterol, Genetics, Population, ATHEROSCLEROSIS, Cardiovascular Diseases, all-cause mortality, Female, Oxidative stress, Homeostasis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb542298437c36f26efb17e6b66df1e7Test
https://research.rug.nl/en/publications/5707fa61-eb31-4f19-8907-d1b65cc4d0f6Test

المؤلفون: Harry van Steeg, Conny T. M. van Oostrom, Ron W. F. de Bruin, Martijn E.T. Dollé, Jan N. M. IJzermans, Jan H.J. Hoeijmakers, Jeroen L. A. Pennings, César Payán-Gómez, F. Jongbloed, Alain de Bruin, Sandra van den Engel

المساهمون: Surgery, Molecular Genetics, LS Pathobiologie, Tissue Repair, PB TR

المصدر: PLoS ONE
Tonelli, M., Wiebe, N., Knoll, G., Bello, A., Browne, S., Systematic review: Kidney transplantation compared with dialysis in clinically relevant outcomes (2011) Am J Transplant, 11, pp. 2093-2109
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
PLoS ONE, Vol 9, Iss 6, p e100853 (2014)
PLoS One, 9(6). Public Library of Science
PLoS One (print), 9(6). Public Library of Science

مصطلحات موضوعية: Male, Envejecido, Adverse Effects, Renal Protection, Lesión por reperfusión, Microarrays, Función del riñón, Obesidad, urologic and male genital diseases, Gene, Vascular Medicine, Biochemistry, Blood Urea Nitrogen, Mice, Oxidative Damage, Pathology, Urea, Medicine, Cyp4A14 Dgene, Blood urea nitrogen, Metabolismo de las vitaminas, Ratones endogámicos C57Bl, Retinol, Messenger Rna, Experimento con animales, Estrés oxidativo, Fasting, Lesión renal, Survival Rate, Factores de edad, Bioassays and Physiological Analysis, Preoperative Period, Nucleotide Sequene, Kidney Injury, C57Bl Mouse, medicine.medical_specialty, Science, Kidney Ischemia, Renal function, Surgical and Invasive Medical Procedures, Exceso de peso, Tissue Regeneration, Animal Tissue, Nivel de sangre de nitrógeno ureico, Kidney Tubule Necrosis, Acute tubular necrosis, Aged, Biology and Life Sciences, Organ Transplantation, Gen Gsta2, Animal Experiment, medicine.disease, Transcription Factor Nrf2, Kidney Function, Mice, Inbred C57BL, Factor de transcripción Nrf2, Endocrinology, Tejido animal, Animal Model, Preoperative fasting, Fatty Acid Oxidation, Reactive Oxygen Species, Isquemia renal, Restricción de la dieta, Necrosis del túbulo renal, Mensajero RNA, Kidney, Gen Sc4Mol, Mice, Inbred C57Bl, Trasplante de riñon, Ischemia, Trasplante de riñón, Medicine and Health Sciences, Renal Transplantation, Nivel de urea en sangre, Kidney transplantation, Metabolismo, Medicine(all), Multidisciplinary, Gen, Agricultural and Biological Sciences(all), Modelo animal, Age Factors, Patología, medicine.anatomical_structure, Reperfusion Injury, Female, Ratón C57Bl, Renal Ischemia, Metabolic Networks and Pathways, Research Article, Vitamin Metabolism, Regeneración de Tejidos, Histopathology, Metabolic Networks And Pathways, Distribución de edad, Stress, Research and Analysis Methods, Glutathione Transferase A2, Age Distribution, Internal medicine, Protección Renal, Cyp4A14 gen D, Tasa de supervivencia, Animals, Obesity, Controlled Study, Nitrógeno ureico en sangre, Glutatión transferasa A2, Urea Blood Level, Estrés, Nutrition, Sc4Mol Gene, Transplantation, Perfiles de expresión génica, Renal ischemia, Biochemistry, Genetics and Molecular Biology(all), business.industry, urogenital system, Gene Expression Profiling, Body Weight, Secuencia de nucleótidos, Oxidación de ácidos grasos, Peso corporal, Estudio controlado, Urea Nitrogen Blood Level, Overweight, Diet Restriction, Período preoperatorio, Kidney Transplantation, Diet, Isquemia, Oxidative Stress, Efectos adversos, Reperfusión, Metabolism, Redes y vías metabólicas, Histopatología, Gsta2 Gene, Energy Metabolism, business, Reperfusion injury, Genetics and Molecular Biology(all)

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445709a61d4deb8543f72181c83a21fcTest
https://doi.org/10.1371/journal.pone.0100853Test

المؤلفون: H. Marike Boezen, Mateusz Siedlinski, Dirkje S. Postma, Henriette A. Smit, Jan P. Schouten, Gerrit van der Steege, Jolanda M. A. Boer

المساهمون: Life Course Epidemiology (LCE), Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: Respiratory Research, Vol 10, Iss 1, p 73 (2009)
Respiratory Research, 10:73. BioMed Central Ltd.
Respiratory Research

مصطلحات موضوعية: Male, Oncology, Cellular detoxification, TRANSCRIPTION FACTOR NRF2, EMPHYSEMA, Cohort Studies, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Risk Factors, ANTIOXIDANT, OXIDATIVE STRESS, ALPHA(1)-ANTITRYPSIN, Netherlands, 2. Zero hunger, 0303 health sciences, education.field_of_study, Kelch-Like ECH-Associated Protein 1, Incidence, Intracellular Signaling Peptides and Proteins, Middle Aged, respiratory system, DEFICIENCY, Cohort, Female, Cohort study, Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, NF-E2-Related Factor 2, Population, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Risk Assessment, OBSTRUCTIVE PULMONARY-DISEASE, 03 medical and health sciences, Internal medicine, LUNG-FUNCTION DECLINE, medicine, Humans, SNP, Genetic Predisposition to Disease, education, Gene, Aged, Maximal Expiratory Flow Rate, 030304 developmental biology, lcsh:RC705-779, Research, lcsh:Diseases of the respiratory system, NFE2L2, Genetics, Population, 030228 respiratory system, CIGARETTE-SMOKE, REPLICATION, Immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ba2a1fb0e27ab17b8431d673a754ecTest
https://doi.org/10.1186/1465-9921-10-73Test

المؤلفون: Jac M.M.J.G. Aarts, Yee Y. Lee-Hilz, Hester van der Woude, Ellen Kampman, Ivonne M.C.M. Rietjens, Martijn Vermeulen, Anne-Marie J. F. Boerboom, Birgit I. Bremer, Peter J. van Bladeren

المساهمون: TNO Kwaliteit van Leven

المصدر: Biochemical Pharmacology, 2, 72, 217-226
Biochemical Pharmacology, 72, 217-26
Biochemical Pharmacology, 72(2), 217-226
Biochemical Pharmacology, 72, 2, pp. 217-26
Biochemical Pharmacology 72 (2006) 2

مصطلحات موضوعية: Nutrition and Disease, Mouse, Transcription, Genetic, Glutathione transferase, Response element, Screening test, antioxidant activity, Drug structure, Gene Expression, Aetiology, screening and detection [ONCOL 5], Toxicology, Chemoprophylaxis, Biochemistry, Gene, chemistry.chemical_compound, Mice, Transient transfection, Genes, Reporter, Voeding en Ziekte, Gene expression, Determinants in Health and Disease [EBP 1], Gene activation, Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone), Luteolin, Luciferases, Regulation of gene expression, protein-kinase-c, Structure activity relation, Genetic transcription, Myricetin, Transcription initiation, Validation study, Molecular interaction, Hepa-1c1c7 cells, inducible expression, Reporter gene, Tandem repeat, consensus sequence, Enzyme Induction, transcription factor nrf2, Quercetin, Benzyl isothiocyanate, Animal cell, Plasmids, Tert butylhydroquinone, Biochemie, Gene induction, Biology, chemopreventive agents, Cell Line, Molecular epidemiology [NCEBP 1], nad(p)h-quinone oxidoreductase, Kaempferol, Cancer screening, Structure-Activity Relationship, Drug potency, Antioxidant activity, Translational research [ONCOL 3], Interventional oncology [UMCN 1.5], Cancer cell culture, Animals, Humans, Luciferase, Enhancer, Molecular Biology, Toxicologie, VLAG, DNA Primers, Pharmacology, Flavonoids, Electrophile-responsive element (EpRE), Taxifolin, Hereditary cancer and cancer-related syndromes [ONCOL 1], Base Sequence, subunit gene, Stable luciferase reporter cell lines, colorectal-cancer, Fisetin, Nonhuman, Molecular biology, chemistry, Human cell, detoxify carcinogens, Stereospecificity, Electrophile responsive element mediated gene, Controlled study

وصف الملف: application/octet-stream; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a66c955569a7a1d9dac8a000f68c8feTest
http://resolver.tudelft.nl/uuid:a7d16055-5432-458e-8dc8-db7264681ea0Test