نتائج البحث - "Frank W.G. Leebeek"

1

Thrombin generation is associated with ischemic stroke at a young age

المؤلفون: Hugo ten Cate, Moniek P.M. de Maat, Diederik W.J. Dippel, Samantha J. Donkel, Frank W.G. Leebeek, Karmen Pater

المساهمون: Hematology, Neurology, Interne Geneeskunde, MUMC+: HVC Trombosezorg (8), MUMC+: MA Alg Interne Geneeskunde (9), MUMC+: HVC Pieken Trombose (9), RS: Carim - B04 Clinical thrombosis and Haemostasis

المصدر: Thrombosis Research, 202, 139-144. Elsevier Ltd.
Thrombosis Research, 202, 139-144. Elsevier Science

مصطلحات موضوعية: Thrombin generation, medicine.medical_specialty, Percentile, Young, 030204 cardiovascular system & hematology, Logistic regression, Gastroenterology, HYPERCOAGULABILITY, PLATELET-RICH PLASMA, MECHANISMS, Brain Ischemia, Transient ischemic attack (TIA), 03 medical and health sciences, 0302 clinical medicine, Thrombin, Internal medicine, medicine, Humans, Prospective Studies, Young adult, THROMBOGRAM, Prospective cohort study, MUTATION, Ischemic Stroke, RISK, business.industry, ADULTS, Hematology, Odds ratio, medicine.disease, Confidence interval, Stroke, ATHEROSCLEROSIS, CARDIOVASCULAR-DISEASE, Case-Control Studies, 030220 oncology & carcinogenesis, business, Case-controls studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a2a6030cec741d8e15795103aee5f3Test
https://doi.org/10.1016/j.thromres.2021.03.028Test

2

Endothelial Dysfunction, Atherosclerosis, and Increase of von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine

المؤلفون: Jens van de Wouw, Daphne Merkus, Dirk J. Duncker, Frank W.G. Leebeek, Moniek P.M. de Maat, Oana Sorop, Ilkka Heinonen, Ferdows Atiq

المساهمون: Hematology, Cardiology

المصدر: Thrombosis and Haemostasis, 121(5), 676-686. Georg Thieme Verlag
Thrombosis and Haemostasis

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Swine, Hypercholesterolemia, Invited T&H Insights, 030204 cardiovascular system & hematology, Gastroenterology, Hemostatics, Diabetes Mellitus, Experimental, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Antigen, Von Willebrand factor, SDG 3 - Good Health and Well-being, law, Internal medicine, Diabetes mellitus, hemic and lymphatic diseases, von Willebrand Factor, medicine, Animals, Endothelial dysfunction, Factor VIII, biology, business.industry, Hematology, Atherosclerosis, Streptozotocin, medicine.disease, Pathophysiology, von Willebrand Diseases, 030104 developmental biology, Endocrinology, biology.protein, Swine, Miniature, Biomarker (medicine), Blood Coagulation Tests, Endothelium, Vascular, business, Biomarkers, Dyslipidemia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd0207de32a04cdb100cef7e69fd1dbTest
http://www.scopus.com/inward/record.url?scp=85099602895&partnerID=8YFLogxKTest

3

Von Willebrand disease type 2M: Correlation between genotype and phenotype

المؤلفون: Annet Simons, Paul P. T. Brons, Frank W.G. Leebeek, Daniëlle Meijer, Selene C M Schoormans, Britta A P Laros-van Gorkom, Waander L. van Heerde, Sandy Krouwel, Laurens Nieuwenhuizen, Dominique P M S M Maas, Nicole M. A. Blijlevens, Saskia E M Schols, Ferdows Atiq

المساهمون: Hematology

المصدر: Journal of Thrombosis and Haemostasis, 20(2), 316-327. Wiley-Blackwell Publishing Ltd
Journal of Thrombosis and Haemostasis, 20, 2, pp. 316-327
Journal of Thrombosis and Haemostasis, 20, 316-327

مصطلحات موضوعية: medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, biology, business.industry, Mucocutaneous zone, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Hematology, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], medicine.disease, Gastroenterology, Cancer development and immune defence Radboud Institute for Health Sciences [Radboudumc 2], Genotype-phenotype distinction, Von Willebrand factor, Antigen, Hemostasis, Internal medicine, hemic and lymphatic diseases, Genotype, medicine, biology.protein, Von Willebrand disease, business, Genotyping, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], circulatory and respiratory physiology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cc08c282316528b8364c12e641bfeaTest
https://pure.eur.nl/en/publications/ddb294bc-b7d6-4300-b9b9-372b6bb0b800Test

4

Population Pharmacokinetic Modeling of von Willebrand Factor Activity in von Willebrand Disease Patients after Desmopressin Administration

المؤلفون: Marjon H. Cnossen, Jessica M. Heijdra, Quincy Kieboom, Frank W.G. Leebeek, Nico C B de Jager, Marieke J. H. A. Kruip, Ron A. A. Mathôt

المساهمون: Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Pharmacy, ACS - Pulmonary hypertension & thrombosis, Hematology, Pediatrics

المصدر: Thrombosis and haemostasis, 120(10), 1407-1416. Schattauer GmbH
Thrombosis and Haemostasis, 120(10), 1407-1416. Georg Thieme Verlag

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Population, empirical PK, 030204 cardiovascular system & hematology, Models, Biological, Gastroenterology, Hemostatics, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Von Willebrand factor, Pharmacokinetics, Internal medicine, hemic and lymphatic diseases, von Willebrand Factor, medicine, Von Willebrand disease, Humans, Deamino Arginine Vasopressin, Dosing, desmopressin response, Child, Desmopressin, education, Aged, Volume of distribution, education.field_of_study, biology, business.industry, Hematology, Middle Aged, medicine.disease, Bioavailability, von Willebrand Diseases, 030104 developmental biology, Child, Preschool, biology.protein, Female, business, von Willebrand disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fe40dd543c5765c901bb870f73199bTest
http://www.scopus.com/inward/record.url?scp=85089861052&partnerID=8YFLogxKTest

5

The one-stage assay or chromogenic assay to monitor baseline factor VIII levels and desmopressin effect in non-severe haemophilia A: Superiority or non-inferiority?

المؤلفون: Marieke J. H. A. Kruip, Luca S Hodes, Iris van Moort, Moniek P.M. de Maat, Sara C. M. Stoof, Lisette M. Schütte, Frank W.G. Leebeek, Marjon H. Cnossen

المساهمون: Hematology, Pediatrics

المصدر: Haemophilia, 26(5), 916-922. Wiley-Blackwell Publishing Ltd
Haemophilia

مصطلحات موضوعية: Adult, Male, desmopressin, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, Haemophilia A, haemophilia A, 030204 cardiovascular system & hematology, Hemophilia A, Gastroenterology, Young Adult, 03 medical and health sciences, chromogenic assay, 0302 clinical medicine, Non inferiority, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Outpatient clinic, Deamino Arginine Vasopressin, one‐stage assay, Desmopressin, Genetics (clinical), Aged, Retrospective Studies, Aged, 80 and over, Factor VIII, business.industry, Chromogenic, One stage, Original Articles, Hematology, General Medicine, Factor VIII Activity, Middle Aged, medicine.disease, Laboratory Science, bleeding phenotype, Original Article, Severe haemophilia A, business, 030215 immunology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee7dfef38a887fd6a8e093240acaeb6Test
https://doi.org/10.1111/hae.14106Test

6

Current dosing practices for perioperative factor VIII concentrate treatment in mild haemophilia A patients result in FVIII levels above target

المؤلفون: Nils de Rooij, Hendrika C A M Hazendonk, Reinier M. van Hest, Marjon H. Cnossen, Lisette M. Schütte, Ron A. A. Mathôt, Marieke J. H. A. Kruip, Frank W.G. Leebeek

المساهمون: Pharmacy, AGEM - Endocrinology, metabolism and nutrition, AGEM - Digestive immunity, AII - Inflammatory diseases, ACS - Pulmonary hypertension & thrombosis, Hematology, Pediatrics

المصدر: Haemophilia. Wiley-Blackwell
Haemophilia, 25(6). Wiley-Blackwell Publishing Ltd

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, animal diseases, Haemophilia A, 030204 cardiovascular system & hematology, Hemophilia A, Target range, Body weight, Gastroenterology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, medicine, Humans, In patient, Dosing, Child, Perioperative Period, Genetics (clinical), Aged, Retrospective Studies, Factor VIII, Dose-Response Relationship, Drug, business.industry, Dosing regimen, Hematology, General Medicine, Perioperative, Middle Aged, medicine.disease, Treatment Outcome, Child, Preschool, Mild haemophilia A, Female, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342b66fcf19b13f5978557795f304e50Test
https://doi.org/10.1111/hae.13838Test

7

Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS

المساهمون: Hematology

المصدر: Blood Adv
Blood advances, 5(15), 2987-3001. American Society of Hematology
Blood Advances, 5(15), 2987-3001. ELSEVIER

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec67b9463a428c1d34effb2c7805a74Test
https://europepmc.org/articles/PMC8361454Test/

8

Gene Transfer with Etranacogene dezaparvovec (AAV5-Padua hFIX variant) in Adults with Severe or Moderate-Severe Hemophilia B: Two Year Data from a Phase 2b Trial

المؤلفون: Michael Recht, Wolfgang Miesbach, Nigel S. Key, Giancarlo Castaman, Esteban Gomez, Steven W. Pipe, Robert Gut, A. von Drygalski, Susan Lattimore, Adam Giermasz, Frank W.G. Leebeek

المصدر: 65th Annual Meeting of the Society of Thrombosis and Haemostasis Research.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, Phase (matter), medicine, Gene transfer, business, Gastroenterology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b61ceccae4fd79877f4a1aad2e95d3e5Test
https://doi.org/10.1055/s-0041-1728090Test

9

AMT-060 Gene Therapy in Adults with Severe or Moderate-Severe Hemophilia B Confirms Stable FIX Expression and Sustained Reductions in Bleeding for up to 5 Years

المؤلفون: Peter Kampmann, Roger E. G. Schutgens, Halvard Bonig, WA Miesbach, Eileen K. Sawyer, Karina Meijer, Frank W.G. Leebeek, Giancarlo Castaman, Michiel Coppens, J Schwaeble, R Klamroth, Erhard Seifried

المصدر: 65th Annual Meeting of the Society of Thrombosis and Haemostasis Research.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Genetic enhancement, Internal medicine, Medicine, business, Gastroenterology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6e0b836c456128c003be1f2f742cc8aeTest
https://doi.org/10.1055/s-0041-1728089Test

10

Dosing of factor VIII concentrate by ideal body weight is more accurate in overweight and obese haemophilia A patients

المؤلفون: Hendrika C A M Hazendonk, Tim Preijers, Frank W.G. Leebeek, R. A. A. Mathôt, Felix J. M. van der Meer, Iris van Moort, Britta A P Laros-van Gorkom, Marjon H. Cnossen, Laurens Nieuwenhuizen, Karina Meijer, Karin Fijnvandraat, Roger E. G. Schutgens

المساهمون: Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Pediatrics, Hematology, Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Haematology, Amsterdam Reproduction & Development (AR&D), Pharmacy

المصدر: British Journal of Clinical Pharmacology, 87(6), 2602-2613. Wiley
British Journal of Clinical Pharmacology, 87, 2602-2613
British Journal of Clinical Pharmacology, 87(6), 2602-2613. Wiley-Blackwell Publishing Ltd
British journal of clinical pharmacology, 87(6), 2602-2613. Wiley-Blackwell
British Journal of Clinical Pharmacology, 87, 6, pp. 2602-2613
British Journal of Clinical Pharmacology

مصطلحات موضوعية: obesity, PHARMACOKINETICS, CLEARANCE, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Ideal Body Weight, CHILDREN, Overweight, 030226 pharmacology & pharmacy, Gastroenterology, 0302 clinical medicine, hemic and lymphatic diseases, Pharmacology (medical), 030212 general & internal medicine, INDEX, Volume of distribution, education.field_of_study, Middle Aged, modelling and simulation, Original Article, medicine.symptom, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, VON-WILLEBRAND-FACTOR, Population, Haemophilia A, RECOMBINANT FACTOR-VIII, MASS, Hemophilia A, Young Adult, 03 medical and health sciences, AGE, Pharmacokinetics, Internal medicine, medicine, Humans, Dosing, education, Aged, Pharmacology, Factor VIII, business.industry, Original Articles, medicine.disease, Obesity, SIZE, haemostasis, business, Body mass index

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ce2ecb1ea7f2d1442bad3d0e357fdaTest
https://research.rug.nl/en/publications/b785c50f-97d8-4f39-b173-ebc413b6381bTest

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