نتائج البحث - "beta-Adrenoceptors"

1

دورية أكاديمية

Distinct Conformations of Mirabegron Determined by MicroED.

المؤلفون: Lin, Jieye¹ (AUTHOR), Unge, Johan¹ (AUTHOR), Gonen, Tamir^1,2,3 (AUTHOR) tgonen@g.ucla.edu

المصدر: Advanced Science. Dec2023, Vol. 10 Issue 34, p1-5. 5p.

مصطلحات موضوعية: *BETA adrenoceptors, *CONFORMERS (Chemistry), *G protein coupled receptors, *HYDROPHOBIC surfaces, *CRYSTAL lattices, *OVERACTIVE bladder, *ELECTRON diffraction

النص الكامل

2

دورية أكاديمية

Real-Time Determination of Intracellular cAMP Reveals Functional Coupling of G s Protein to the Melatonin MT 1 Receptor.

المؤلفون: Tse, Lap Hang, Cheung, Suet Ting, Lee, Seayoung, Wong, Yung Hou

المصدر: International Journal of Molecular Sciences; Mar2024, Vol. 25 Issue 5, p2919, 18p

مصطلحات موضوعية: G proteins, G protein coupled receptors, ADENYLATE cyclase, MELATONIN, FORSKOLIN, CIRCADIAN rhythms, BETA adrenoceptors, CYCLIC-AMP-dependent protein kinase

النص الكامل

3

دورية أكاديمية

Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor.

المؤلفون: Xu, Hang, Yang, Na, Wang, Bao‐Yan, Zhou, Lin, Xu, Li‐Li, Chen, Yan, Wang, Dong‐Jin, Ge, Wei‐Hong

المصدر: Environmental Toxicology; Mar2024, Vol. 39 Issue 3, p1682-1699, 18p

مصطلحات موضوعية: ADRENERGIC receptors, MYOCARDIAL infarction, G protein coupled receptors, GLUTAMINE, MYOCARDIAL injury, METABOLOMICS, ANDROGEN receptors, BETA adrenoceptors

4

دورية أكاديمية

Role of G protein‐coupled receptor kinases (GRKs) in β2‐adrenoceptor‐mediated glucose uptake.

المؤلفون: Ham, Seungmin, Mukaida, Saori, Sato, Masaaki, Keov, Peter, Bengtsson, Tore, Furness, Sebastian, Holliday, Nicholas D., Evans, Bronwyn A., Summers, Roger J., Hutchinson, Dana S.

المصدر: Pharmacology Research & Perspectives; Feb2024, Vol. 12 Issue 1, p1-16, 16p

مصطلحات موضوعية: G protein-coupled receptor kinases, G protein coupled receptors, FLUORESCENCE resonance energy transfer, GLUCOSE, BETA adrenoceptors, SCAFFOLD proteins

النص الكامل

5

دورية أكاديمية

Inhibiting Intracellular α 2C -Adrenoceptor Surface Translocation Using Decoy Peptides: Identification of an Essential Role of the C-Terminus in Receptor Trafficking.

المؤلفون: Raza, Aisha, Mohsin, Saima, Saeed, Fasiha, Ali, Syed Abid, Chotani, Maqsood A.

المصدر: International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 24, p17558, 21p

مصطلحات موضوعية: AMINO acid residues, RAYNAUD'S disease, PEPTIDES, PERIPHERAL vascular diseases, ALPHA adrenoceptors, MICROFILAMENT proteins, G protein coupled receptors, BETA adrenoceptors

النص الكامل

6

دورية أكاديمية

CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in Gαs-Gαi coupling to the β2-adrenergic receptor.

المؤلفون: Ge, Mingli, Wu, Li, He, Feng, Tai, Yu, Fang, Ruhong, Han, Dafei, Guo, Paipai, Liu, Hao, Hu, Yong, Xu, Shenglin, Wei, Wei, Wang, Qingtong

المصدر: Cell Communication & Signaling; 11/30/2023, Vol. 21 Issue 1, p1-17, 17p

مصطلحات موضوعية: FLUORESCENCE resonance energy transfer, G protein coupled receptors, ADRENERGIC receptors, SMALL interfering RNA, COLLAGEN-induced arthritis, BETA adrenoceptors, PATHOLOGICAL physiology

النص الكامل

7

دورية أكاديمية

Novel roles for G protein-coupled receptor kinases in cardiac injury and repair.

المؤلفون: Kayki-Mutlu, Gizem, Koch, Walter J.

المصدر: Biochemical Society Transactions; Apr2023, Vol. 51 Issue 2, p715-724, 10p

مصطلحات موضوعية: G protein-coupled receptor kinases, G protein coupled receptors, CORONARY circulation, HEART injuries, ANGIOTENSIN-receptor blockers, BETA adrenoceptors

8

دورية أكاديمية

Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands.

المؤلفون: Shpakov, Alexander O.

المصدر: International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 7, p6187, 54p

مصطلحات موضوعية: ALLOSTERIC regulation, LUTEINIZING hormone receptors, G protein coupled receptors, ARRESTINS, TRANSMEMBRANE domains, BETA adrenoceptors, MOLECULAR docking, CHEMOKINE receptors

النص الكامل

9

دورية أكاديمية

Application of the PET ligand [11C]ORM-13070 to examine receptor occupancy by the α2C-adrenoceptor antagonist ORM-12741: translational validation of target engagement in rat and human brain.

المؤلفون: Shahid, Mohammed^1,2 (AUTHOR), Rinne, Juha O.^3,4 (AUTHOR), Scheinin, Mika^5,6,7 (AUTHOR), Virta, Jere^3,4 (AUTHOR), Marjamäki, Päivi^3,8 (AUTHOR), Solin, Olof^3,9,10 (AUTHOR), Arponen, Eveliina³ (AUTHOR), Sallinen, Jukka¹ (AUTHOR), Kuokkanen, Katja¹ (AUTHOR), Rouru, Juha¹ (AUTHOR) juha.rouru@orionpharma.com

المصدر: EJNMMI Research. 12/9/2020, Vol. 10 Issue 1, p1-9. 9p.

مصطلحات موضوعية: *BETA adrenoceptors, *G protein coupled receptors, *ALPHA adrenoceptors, *POSITRON emission tomography, *CAUDATE nucleus, *RATS, *BASAL ganglia

النص الكامل

10

دورية أكاديمية

Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor.

المؤلفون: Burghi, Valeria^1,2, Paradis, Justine S.^1,2, Officer, Adam^1,2, Adame-Garcia, Sendi Rafael^1,2, Xingyu Wu^1,2, Matthees, Edda S. F.³, Barsi-Rhyne, Benjamin⁴, Ramms, Dana J.^1,2, Clubb, Lauren^1,2, Acosta, Monica^1,2, Tamayo, Pablo¹, Bouvier, Michel⁵, Asuka Inoue⁶, von Zastrow, Mark⁷, Hoffmann, Carsten³, Gutkind, J. Silvio^1,2 sgutkind@health.ucsd.edu

المصدر: Journal of Biological Chemistry. Nov2023, Vol. 299 Issue 11, p1-19. 19p.

مصطلحات موضوعية: *GENETIC regulation, *G protein coupled receptors, *BETA adrenoceptors, *MITOGEN-activated protein kinases, *MITOGEN-activated protein kinase kinase, *CYCLIC-AMP-dependent protein kinase, *PROTEIN kinases

النص الكامل

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