نتائج البحث - "Agostina Nardone"

1

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

2

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy

المساهمون: Giuliano, Mario, Hu, H, Wang, Yc, Fu, X, Nardone, Agostina, Herrera, S, Mao, S, Contreras, A, Gutierrez, C, Wang, T, Hilsenbeck, Sg, DE ANGELIS, Carmine, Wang, Nj, Heiser, Lm, Gray, Jw, Lopez Tarruella, S, Pavlick, Ac, Trivedi, Mv, Chamness, Gc, Chang, Jc, Osborne, Ck, Rimawi, Mf, Schiff, R.

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Antineoplastic Agents, Hormonal, Cell Survival, Receptor, ErbB-2, medicine.medical_treatment, Gene Expression, Estrogen receptor, Breast Neoplasms, Lapatinib, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Internal medicine, Animals, Humans, Medicine, Molecular Targeted Therapy, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, biology, Fulvestrant, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Neoadjuvant Therapy, Disease Models, Animal, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Tumor progression, Quinazolines, Cancer research, biology.protein, Female, Receptors, Progesterone, business, Biomarkers, Signal Transduction, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b1598f486d1beb5e4551a1d1f12f3dTest
https://doi.org/10.1158/1078-0432.ccr-14-2728Test

3

Abstract B16: Mathematical modeling identifies optimum palbociclib dosing schedules for the treatment of estrogen receptor-positive (ER+) breast cancer patients

المؤلفون: C. Guarducci, Gabriella Cohen, Agostina Nardone, Myles Brown, Franziska Michor, Weihan Liu, Rinath Jeselsohn, Shayna Stein

المصدر: Cancer Research. 80:B16-B16

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Combination therapy, Fulvestrant, business.industry, Cancer, Palbociclib, medicine.disease, Clinical trial, chemistry.chemical_compound, Breast cancer, chemistry, Internal medicine, Medicine, Dosing, business, Abemaciclib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e477fd0549d606fc96ed8ae6f6238c43Test
https://doi.org/10.1158/1538-7445.camodels2020-b16Test

4

Combination of fulvestrant and chemotherapy in ESR1 Y537S mutant breast cancer cells and potential synergy mechanism related to p53 wildtype

المؤلفون: Ma Wen, Nanlin Li, C. Guarducci, Avery S. Feit, Rinath Jeseslsohn, Gabriella Cohen, Francisco Hermida-Prado, Hongliang Wei, Myles Brown, Wenting Pan, Agostina Nardone

المصدر: Journal of Clinical Oncology. 38:1065-1065

مصطلحات موضوعية: Cancer Research, Chemotherapy, Fulvestrant, Mechanism (biology), business.industry, medicine.medical_treatment, Mutant, Wild type, medicine.disease, Breast cancer, Oncology, medicine, Cancer research, Endocrine system, business, Estrogen receptor alpha, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::815a31bb038416860d6bf7963387a5fdTest
https://doi.org/10.1200/jco.2020.38.15_suppl.1065Test

5

Abstract GS2-01: High levels of interferon-response gene signatures are associated with de novo and acquired resistance to CDK4/6 inhibitors in ER+ breast cancer

المصدر: Cancer Research. 80:GS2-01

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::62707dc1c64c8977590881b9cb8aac63Test
https://doi.org/10.1158/1538-7445.sabcs19-gs2-01Test

6

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

المؤلفون: Nicholas Mitsiades, Rainer B. Lanz, Cristian Coarfa, Chad J. Creighton, Zheng Zhang, Yongcheng Song, Xiaoyong Fu, Bert W. O'Malley, C. Kent Osborne, Qin Feng, Constantine S. Mitsiades, Bin He, Agostina Nardone, James E. Bradner, Martin Shea, Rachel Schiff, Lei Wang, Susan G. Hilsenbeck

المصدر: Cell Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c16f2d3cdf58d637fb10ef1da2be07Test
https://doi.org/10.1038/cr.2014.71Test

7

Abstract P5-09-20: Development of a novel selective estrogen receptor down-regulator which shows efficacy in pre-clinical models of endocrine resistance

المؤلفون: Zena Wilson, Jon Curwen, Ermira Pazolli, Michael Hulse, N Reavey, Graeme Walker, Rachel Schiff, A.A. Rabow, Mandy Lawson, Rob H. Bradbury, Steve Powell, Agostina Nardone, Rachel Rowlinson, Celina M. D'Cruz, C. De Savi, Rowena Callis, Hazel M. Weir

المصدر: Cancer Research. 73:P5-09

مصطلحات موضوعية: Cancer Research, Fulvestrant, biology, medicine.drug_class, business.industry, Cancer, Pharmacology, medicine.disease, Breast cancer, Oncology, Estrogen, medicine, biology.protein, Aromatase, business, Estrogen receptor alpha, Selective Estrogen Receptor Down Regulator, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c923447479bae56bc973afe1a903e8b2Test
https://doi.org/10.1158/0008-5472.sabcs13-p5-09-20Test

8

Abstract P3-05-03: Reversal of endocrine therapy resistance with inhibitors of AKT, mTOR, or MEK as single agents or in combination

المؤلفون: Agostina Nardone, Gladys Morrison, Rachel Schiff, C. Kent Osborne, Tamika Mitchell, Teresa Klinowska, Xiaoyong Fu, Martin Shea

المصدر: Cancer Research. 75:P3-05

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, medicine.medical_specialty, Fulvestrant, Cell growth, Chemistry, Kinase, chemistry.chemical_compound, Endocrinology, Oncology, Growth factor receptor, Internal medicine, medicine, Cancer research, Growth inhibition, Protein kinase B, PI3K/AKT/mTOR pathway, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1ceb6f2ab9588e02b45c7e74bd406f23Test
https://doi.org/10.1158/1538-7445.sabcs14-p3-05-03Test

9

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

المساهمون: Fu, Xiaoyong, Creighton, Chad J., Biswal, Nrusingh C., Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Glady, Nardone, Agostina, Karlin, Kristen L., Westbrook, Thomas F., Heiser, Laura M., Anur, Pavana, Spellman, Paul, Guichard, Sylvie M., Smith, Paul D., Davies, Barry R., Klinowska, Teresa, Lee, Adrian V., Mills, Gordon B., Rimawi, Mothaffar F., Hilsenbeck, Susan G., Gray, Joe W., Joshi, Amit, Osborne, C. K., Schiff, Rachel

المصدر: Breast Cancer Research : BCR

مصطلحات موضوعية: Cancer Research, Gene Expression, Mitogen-activated protein kinase kinase, Mitogen-Activated Protein Kinase, Phosphatidylinositol 3-Kinases, MCF-7 Cell, Sirolimu, ASK1, Molecular Targeted Therapy, Fulvestrant, Medicine(all), TOR Serine-Threonine Kinase, biology, Estradiol, TOR Serine-Threonine Kinases, 3. Good health, Editorial, Oncology, Receptors, Estrogen, Doxycycline, Gene Knockdown Techniques, MCF-7 Cells, Female, Mitogen-Activated Protein Kinases, Breast Neoplasm, Research Article, Human, Signal Transduction, Xenograft Model Antitumor Assay, Neoplasms, Hormone-Dependent, Antineoplastic Agents, Hormonal, Protein Kinase Inhibitor, Mice, Nude, Breast Neoplasms, PTEN, Animals, Humans, c-Raf, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Sirolimus, Animal, Cyclin-dependent kinase 4, Akt/PKB signaling pathway, PTEN Phosphohydrolase, Xenograft Model Antitumor Assays, Tamoxifen, Drug Resistance, Neoplasm, Gene Knockdown Technique, biology.protein, Cancer research, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b8e05d376b25b5859d608cc00f5d0fTest
https://pubmed.ncbi.nlm.nih.gov/25888162Test

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