Irpexoates A–D, Four Triterpenoids with Malonyl Modifications from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus
| العنوان: | Irpexoates A–D, Four Triterpenoids with Malonyl Modifications from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus |
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| المؤلفون: | Ji-Kai Liu, Zheng-Hui Li, He-Ping Chen, Zhen-Zhu Zhao, Tao Feng, Yang Tang |
| المصدر: | Natural Products and Bioprospecting, Vol 8, Iss 3, Pp 171-176 (2018) Natural Products and Bioprospecting |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Stereochemistry, Cytotoxicity, Irpex lacteus, Plant Science, Fungus, Toxicology, 01 natural sciences, Biochemistry, Analytical Chemistry, Triterpenoid, lcsh:Botany, Ic50 values, Bioorganic chemistry, Pharmacology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Meruliaceae, Eburicane, biology.organism_classification, lcsh:QK1-989, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Original Article, Two-dimensional nuclear magnetic resonance spectroscopy, Human cancer, Malonyl, Food Science |
| الوصف: | Four eburicane-type triterpenoids with malonyl modifications, namely irpexoates A–D (1–4), were isolated from the fruiting bodies of the medicinal fungus Irpex lacteus. The structures of the new compounds were established by extensive spectroscopic methods, including 1D and 2D NMR, HRESIMS spectroscopic analysis. Irpexoate B (2) displayed weak cytotoxicity against four human cancer cell lines (A-549, SMMC-7721, MCF-7, SW480) with IC50 values varying from 22.9 to 34.0 μM, and irpexoate D (4) showed weak cytotoxicity against the human cancer cell line SW480 with an IC50 value of 35.2 μM. Graphical Abstract Electronic supplementary material The online version of this article (10.1007/s13659-018-0160-3) contains supplementary material, which is available to authorized users. |
| تدمد: | 2192-2209 2192-2195 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56567936e7499ca92cf0e29d36ecda3Test https://doi.org/10.1007/s13659-018-0160-3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e56567936e7499ca92cf0e29d36ecda3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21922209 21922195 |
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