التفاصيل البيبلوغرافية
| العنوان: |
Detection of Abdominal Lymph Node Metastasis from Pancreatic Neuroendocrine Tumor by Somatostatin Receptor Scintigraphy: Comparison with Somatostatin Receptor Type 2 Immunostaining. |
| المؤلفون: |
Kitajima, Kazuhiro, Shiomi, Hideyuki, Kihara, Takako, Hirono, Seiko, Nakano, Ryota, Okamoto, Tomohiro, Yagi, Chisako, Eda, Hirotsugu, Matsuda, Kosuke, Hatano, Michiko, Yoshida, Makoto, Kono, Hiroshi, Hirota, Seiichi, Minami, Tetsuya, Yamakado, Koichiro |
| المصدر: |
Case Reports in Oncology; 2023, Vol. 16 Issue 1, p543-549, 7p |
| مصطلحات موضوعية: |
SOMATOSTATIN receptors, LYMPHATIC metastasis, PANCREATIC tumors, NEUROENDOCRINE tumors, RADIONUCLIDE imaging, POSITRON emission tomography |
| مستخلص: |
We report a 58-year-old male with a histopathologically proven grade 2 (G2) pancreatic neuroendocrine neoplasm and multiple abdominal node metastases by use of a laparoscopic pancreatic body and tail resection procedure, plus abdominal lymph node dissection. A primary pancreatic tail neuroendocrine tumor sized 20 × 25 mm was detected by contrast-enhanced computed tomography, somatostatin receptor scintigraphy (SRS), and fluorodeoxyglucose positron emission tomography (FDG-PET) examinations and pathologically diagnosed as a pancreatic neuroendocrine tumor (PNET, G2) based on positive immunostaining for somatostatin receptor (SSTR) type 2. Of three metastatic histopathological lymph nodes, two measured 18 × 21 and 10 × 12 mm, respectively, with whole strong SSTR immunostaining showing moderate uptake in SRS findings, whereas the other node, sized 8 × 10 mm, had strong SSTR immunostaining only in a small 6 × 6-mm-sized portion and showed no uptake in SRS findings, likely because of the limited spatial resolution of scintigraphy. On the other hand, only the largest node (18 × 21 mm) was visualized by FDG-PET. SRS may be useful for metastatic lymph node diagnosis based on SSTR immunostaining, though a disadvantage is the spatial resolution limitation. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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