دورية أكاديمية
Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease
| العنوان: | Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease |
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| المؤلفون: | Wegrzyniak, Olivia, Rosestedt, Maria, Eriksson, Olof |
| بيانات النشر: | Uppsala universitet, Translationell avbildning med PET Uppsala universitet, Science for Life Laboratory, SciLifeLab Uppsala universitet, Institutionen för läkemedelskemi Antaros Med AB, SE-43183 Mölndal, Sweden |
| سنة النشر: | 2021 |
| المجموعة: | Uppsala University: Publications (DiVA) |
| مصطلحات موضوعية: | positron emission tomography, imaging, immune cells, fibroblasts, collagen, fibrosis, NASH, Gastroenterology and Hepatology, Gastroenterologi |
| الوصف: | Pathological fibrosis of the liver is a landmark feature in chronic liver diseases, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Diagnosis and assessment of progress or treatment efficacy today requires biopsy of the liver, which is a challenge in, e.g., longitudinal interventional studies. Molecular imaging techniques such as positron emission tomography (PET) have the potential to enable minimally invasive assessment of liver fibrosis. This review will summarize and discuss the current status of the development of innovative imaging markers for processes relevant for fibrogenesis in liver, e.g., certain immune cells, activated fibroblasts, and collagen depositions. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | International Journal of Molecular Sciences, 1661-6596, 2021, 22:14; orcid:0000-0002-2515-8790; http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-453378Test; PMID 34298967; ISI:000676634600001 |
| DOI: | 10.3390/ijms22147348 |
| الإتاحة: | https://doi.org/10.3390/ijms22147348Test http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-453378Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.42E6A9A7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/ijms22147348 |
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