دورية أكاديمية
Identification of high-risk subjects in nonalcoholic fatty liver disease
| العنوان: | Identification of high-risk subjects in nonalcoholic fatty liver disease |
|---|---|
| المؤلفون: | Christiane Stern, Laurent Castera |
| المصدر: | Clinical and Molecular Hepatology, Vol 29, Iss Suppl, Pp S196-S206 (2023) |
| بيانات النشر: | Korean Association for the Study of the Liver, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | non-alcoholic fatty liver disease, elastography, vibration controlled transient elastography, fibroscan, liver fibrosis, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Non-alcoholic fatty liver disease (NAFLD) is becoming the most common liver disease worldwide, and its burden is expected to increase due to the growing epidemic of obesity and diabetes. The key challenge among NAFLD patients is to identify those with advanced fibrosis (F3F4), who are at high risk of developing complications and will benefit from specialized management and treatment with new pharmacotherapies when they are approved. Liver biopsy appears unrealistic and unsuitable in practice, given the large number of high-risk patients and its well-known limitations. Non-invasive sequential algorithms using fibrosis-4 index as first-line test, followed by vibration-controlled transient elastography or patented blood test, are the best strategy for case finding of high-risk subjects. In fact, they are now recommended by several international guidelines, and should be used and disseminated to increase awareness among physicians beyond liver clinics where most NAFLD patients are seen. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2287-2728 2287-285X |
| العلاقة: | http://e-cmh.org/upload/pdf/cmh-2022-0431.pdfTest; https://doaj.org/toc/2287-2728Test; https://doaj.org/toc/2287-285XTest |
| DOI: | 10.3350/cmh.2022.0431 |
| الوصول الحر: | https://doaj.org/article/4fe007530809476399fcd0448a782611Test |
| رقم الانضمام: | edsdoj.4fe007530809476399fcd0448a782611 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22872728 2287285X |
|---|---|
| DOI: | 10.3350/cmh.2022.0431 |