نتائج البحث - "Melissa E. Hughes"

1

Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program

المصدر: Clin Cancer Res

مصطلحات موضوعية: BRCA2 Protein, Lipopolysaccharides, Male, Cancer Research, BRCA1 Protein, Article, Oncology, Neoplasms, Humans, Female, Genetic Predisposition to Disease, Genetic Testing, Fanconi Anemia Complementation Group N Protein, Germ-Line Mutation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6eb4a4a5c07d9317829d420b37a90c1Test
https://doi.org/10.1158/1078-0432.ccr-21-2861Test

2

Prognostic and Biologic Significance of ERBB2-Low Expression in Early-Stage Breast Cancer

المؤلفون: Paolo Tarantino, Qingchun Jin, Nabihah Tayob, Rinath M. Jeselsohn, Stuart J. Schnitt, Julie Vincuilla, Tonia Parker, Svitlana Tyekucheva, Tianyu Li, Nancy U. Lin, Melissa E. Hughes, Anna C. Weiss, Tari A. King, Elizabeth A. Mittendorf, Giuseppe Curigliano, Sara M. Tolaney

المصدر: JAMA Oncol

مصطلحات موضوعية: Adult, Aged, 80 and over, Male, Cancer Research, Biological Products, Receptor, ErbB-2, Breast Neoplasms, Triple Negative Breast Neoplasms, Middle Aged, Prognosis, Neoadjuvant Therapy, Cohort Studies, Young Adult, Oncology, Humans, Female, Original Investigation, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78815cd688e82efad1c1fb556c83cdc5Test
https://europepmc.org/articles/PMC9227690Test/

3

STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

المؤلفون: Qiwei Wang, Johann S. Bergholz, Liya Ding, Ziying Lin, Sheheryar K. Kabraji, Melissa E. Hughes, Xiadi He, Shaozhen Xie, Tao Jiang, Weihua Wang, Jason J. Zoeller, Hye-Jung Kim, Thomas M. Roberts, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Deborah A. Dillon, Eric P. Winer, Nancy U. Lin, Jean J. Zhao

المصدر: Nature Communications. 13

مصطلحات موضوعية: Multidisciplinary, BRCA1 Protein, General Physics and Astronomy, Breast Neoplasms, General Chemistry, CD8-Positive T-Lymphocytes, Poly(ADP-ribose) Polymerase Inhibitors, General Biochemistry, Genetics and Molecular Biology, Mice, Tumor-Associated Macrophages, Animals, Humans, Female, Synthetic Lethal Mutations

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ef4d90d9e4b10b6b3acec1f122082aTest
https://doi.org/10.1038/s41467-022-30568-1Test

4

The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer

المصدر: Cancer Discovery. 10:1174-1193

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Receptors, Steroid, Biopsy, Ubiquitin-Protein Ligases, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Cell Cycle Proteins, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, Exome Sequencing, Humans, Medicine, Protein Kinase Inhibitors, biology, business.industry, Kinase, Cyclin-dependent kinase 4, Genomics, medicine.disease, Metastatic breast cancer, Retinoblastoma Binding Proteins, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Checkpoint Kinase 1, Cancer cell, Cancer research, biology.protein, Female, KRAS, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4ba02ffa18791bc5e2dafc527cfa80Test
https://doi.org/10.1158/2159-8290.cd-19-1390Test

5

Subtype switching in breast cancer brain metastases: a multicenter analysis

المؤلفون: Priscilla K. Brastianos, Melissa E. Hughes, Alexander F. C. Hulsbergen, Joost J.C. Verhoeff, Timothy R. Smith, Vasileios K. Kavouridis, An Claes, Marike L. D. Broekman, Ali Ansaripour, Nan Lin, Claudine O. Nogarede

المصدر: Neuro-Oncology
Neuro-Oncology, 22(8), 1173-1181. OXFORD UNIV PRESS INC
Neuro Oncol

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Receptor, ErbB-2, medicine.drug_class, Receptor expression, Clinical Investigations, Breast Neoplasms, subtype, Surgical pathology, 03 medical and health sciences, breast cancer, 0302 clinical medicine, Breast cancer, brain metastases, Internal medicine, Biopsy, Biomarkers, Tumor, medicine, AcademicSubjects/MED00300, Humans, Neoplasm Metastasis, Retrospective Studies, medicine.diagnostic_test, Brain Neoplasms, business.industry, Incidence (epidemiology), Hazard ratio, Editorials, Middle Aged, Prognosis, medicine.disease, Primary tumor, 030104 developmental biology, Estrogen, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Female, AcademicSubjects/MED00310, Neurology (clinical), receptor discordance, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd28f7d220f54f7e6dfa1316ef2ed9c2Test
https://doi.org/10.1093/neuonc/noaa013Test

6

Association between the 21-gene recurrence score and isolated locoregional recurrence in stage I-II, hormone receptor-positive breast cancer

المؤلفون: Stephen B. Edge, Beverly Moy, Michael J. Hassett, Melissa E. Hughes, Adam L. Cohen, Sara H. Javid, Shicheng Weng, Angel M. Cronin, Daniela L. Buscariollo, Antonio C. Wolff, Rinaa S. Punglia, Richard J. Bleicher, David D. Yang, Joyce C. Niland

المصدر: Radiation Oncology (London, England)
Radiation Oncology, Vol 15, Iss 1, Pp 1-7 (2020)

مصطلحات موضوعية: lcsh:Medical physics. Medical radiology. Nuclear medicine, Oncology, medicine.medical_specialty, lcsh:R895-920, medicine.medical_treatment, Breast Neoplasms, Mastectomy, Segmental, lcsh:RC254-282, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, medicine, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, Prospective Studies, Stage (cooking), Locoregional recurrence, Neoadjuvant therapy, Aged, Neoplasm Staging, business.industry, Gene Expression Profiling, Research, Hazard ratio, Recurrence score, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Confidence interval, Radiation therapy, Treatment Outcome, Receptors, Estrogen, 030220 oncology & carcinogenesis, Cohort, Female, Neoplasm Recurrence, Local, business, Receptors, Progesterone, Mastectomy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb25d15a19daa671ae1739a511916b89Test
https://pubmed.ncbi.nlm.nih.gov/32799886Test

7

Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer

المصدر: Clin Cancer Res
PMC

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Cancer Research, medicine.medical_specialty, Neoplasm, Residual, Breast Neoplasms, Article, Circulating Tumor DNA, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, medicine, Humans, Prospective Studies, Stage (cooking), Prospective cohort study, Survival rate, Retrospective Studies, business.industry, Estrogen Receptor alpha, Retrospective cohort study, medicine.disease, Prognosis, Minimal residual disease, Metastatic breast cancer, Combined Modality Therapy, Confidence interval, Survival Rate, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Neoplasm Recurrence, Local, business, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2318a87a074383f9e262de4c851f066Test
https://europepmc.org/articles/PMC7654718Test/

8

TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes

مصطلحات موضوعية: 0301 basic medicine, Adult, Cancer Research, Poly ADP ribose polymerase, Phases of clinical research, Breast Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, medicine.disease_cause, Piperazines, Olaparib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, Neoplasm Metastasis, Homologous Recombination, skin and connective tissue diseases, Gene, Polymerase, Aged, Aged, 80 and over, Mutation, biology, business.industry, Middle Aged, medicine.disease, Metastatic breast cancer, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Phthalazines, Female, Homologous recombination, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d957314aca664977912fc4e904535eTest

9

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy inBRCA1/2-mutant metastatic breast cancer

المصدر: Ann Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1d8171b82dabbd9ff0c9160f4f77a7Test
https://doi.org/10.1101/832717Test

10

Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer

المصدر: Journal of Clinical Oncology. 36:543-553

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, DNA Copy Number Variations, medicine.medical_treatment, Triple Negative Breast Neoplasms, Circulating Tumor DNA, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Humans, Medicine, Neoplasm Metastasis, Triple-negative breast cancer, Aged, Retrospective Studies, Chromosome Aberrations, Chemotherapy, business.industry, Hazard ratio, Retrospective cohort study, Middle Aged, Prognosis, medicine.disease, 030104 developmental biology, Cell-free fetal DNA, 030220 oncology & carcinogenesis, Female, Chromosomes, Human, Pair 18, business, Chromosomes, Human, Pair 19

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4fc271b8435c00b3302338da6071eb2Test
https://doi.org/10.1200/jco.2017.76.0033Test

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