المؤلفون: Masayuki Sasaki, Christian U. Oeing, Dong Ik Lee, Djahida Bedja, Mark J. Ranek, Taishi Nakamura, Jonathan D. Powell, Jennifer E. Van Eyk, Chirag H. Patel, Anna Chen, Miguel Pinilla Vera, Ronald J. Holewinski, Kristen M. Kokkonen-Simon, Guangshuo Zhu, David A. Kass, Brittany Dunkerly-Eyring

المصدر: Nature

مصطلحات موضوعية: Male, 0301 basic medicine, Heart Diseases, mTORC1, Mechanistic Target of Rapamycin Complex 1, 030204 cardiovascular system & hematology, Article, Mice, Phosphoserine, 03 medical and health sciences, 0302 clinical medicine, Tuberous Sclerosis Complex 2 Protein, Autophagy, Cyclic GMP-Dependent Protein Kinases, Pressure, Serine, Animals, Humans, Myocytes, Cardiac, Everolimus, Gene Knock-In Techniques, Phosphorylation, Rats, Wistar, Protein kinase A, Mechanistic target of rapamycin, Protein kinase B, Cells, Cultured, Pressure overload, Multidisciplinary, biology, Kinase, Chemistry, Hypertrophy, Rats, Cell biology, Enzyme Activation, HEK293 Cells, 030104 developmental biology, Mutation, Disease Progression, biology.protein, Female, biological phenomena, cell phenomena, and immunity, RHEB

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963ccf5739aaa5a72e9b1e7524e814d8Test
https://doi.org/10.1038/s41586-019-0895-yTest

المؤلفون: Brittany Dunkerly-Eyring, Danielle Dillard, Masayuki Sasaki, Peter P. Rainer, Kristen M. Kokkonen-Simon, David A. Kass, Sumita Mishra, Richard C. Page, Jennifer E. Van Eyk, Virginia S. Hahn, Matthew M. Mannion, Huaqun Zhang, Christian U. Oeing, M. Imran Aslam, Mark J. Ranek, Ronald J. Holewinski, Jonathan C. Schisler, Dong I. Lee, Cornelia Virus, Monte S. Willis, Rebekah Sanchez-Hodge, Vineet Agrawal

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, Science, Ubiquitin-Protein Ligases, Amino Acid Motifs, General Physics and Astronomy, macromolecular substances, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Ischemia, Cyclic GMP-Dependent Protein Kinases, Animals, Humans, Phosphorylation, lcsh:Science, Multidisciplinary, biology, Chemistry, Myocardium, Protein turnover, Heart, General Chemistry, Cell biology, Myocardial infarction, Mechanisms of disease, 030104 developmental biology, Proteostasis, Proteasome, Proteotoxicity, Chaperone (protein), cardiovascular system, biology.protein, lcsh:Q, Female, cGMP-dependent protein kinase, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0da9f09773c6c255e955440f56caa0eTest
https://doi.org/10.1038/s41467-020-18980-xTest

المؤلفون: Fredrick M. Wigley, Marc K. Halushka, Kenneth B. Margulies, Steven Hsu, Rachel L. Damico, Paul M. Hassoun, Monica Mukherjee, Kristen M. Kokkonen-Simon, Ami A. Shah, Ryan J. Tedford, David A. Kass, Todd M. Kolb, Stephen C. Mathai, Jonathan A. Kirk

المصدر: Circulation. 137:2360-2370

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Myofilament, Heart Ventricles, Hypertension, Pulmonary, 030204 cardiovascular system & hematology, Sarcomere, Article, Contractility, 03 medical and health sciences, 0302 clinical medicine, Myofibrils, In vivo, Physiology (medical), Internal medicine, medicine, Humans, Myocyte, Familial Primary Pulmonary Hypertension, Prospective Studies, skin and connective tissue diseases, Exercise, Aged, Scleroderma, Systemic, integumentary system, business.industry, Myocardium, Hemodynamics, Idiopathic Pulmonary Arterial Hypertension, Middle Aged, medicine.disease, Pulmonary hypertension, 030228 respiratory system, Case-Control Studies, Cardiology, Calcium, Female, Cardiology and Cardiovascular Medicine, business, Myofibril, Muscle Contraction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6613723f5d08a96fe9ded025ae164e7Test
https://doi.org/10.1161/circulationaha.117.033147Test