المؤلفون: William F. Hancock-Cerutti, Daniel J. Rader, John S. Millar, Silvia Valentini, Jeffrey T. Billheimer, Marina Cuchel, Jason J. Liu

المصدر: Molecules
Volume 26
Issue 22
Molecules, Vol 26, Iss 6862, p 6862 (2021)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Apolipoprotein B, Pharmaceutical Science, Organic chemistry, Article, Analytical Chemistry, Coronary artery disease, Basal (phylogenetics), chemistry.chemical_compound, QD241-441, In vivo, Internal medicine, Drug Discovery, medicine, Humans, Physical and Theoretical Chemistry, Aged, lipoprotein metabolism, biology, Apolipoprotein A-I, Chemistry, Cholesterol, Cholesterol, HDL, nutritional and metabolic diseases, Middle Aged, hyperalphalipoprotenemia, medicine.disease, Lipids, Endocrinology, Chemistry (miscellaneous), biology.protein, Cholesteryl ester, Molecular Medicine, Female, lipids (amino acids, peptides, and proteins), Efflux, Lipoproteins, HDL, Ex vivo, cholesterol efflux, coronary artery disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706ccc59bb983e59a1430e517e648eb4Test

المؤلفون: John S. Millar, Laurens F. Reeskamp, Hans Jansen, Geesje M. Dallinga-Thie, G. Kees Hovingh, Dewi van Harskamp, Henk Schierbeek, Liya Wu, Daniel J. Rader, Daniel A. Gipe, Marina Cuchel

المساهمون: Graduate School, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, General Paediatrics, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Experimental Vascular Medicine

المصدر: Arteriosclerosis, thrombosis, and vascular biology, 41(5), 1753-1759. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology

مصطلحات موضوعية: Male, Very low-density lipoprotein, Time Factors, Apolipoprotein B, Familial hypercholesterolemia, chemistry.chemical_compound, Translational Sciences, ANGPTL3, Netherlands, biology, familial hypercholesterolemia, Anticholesteremic Agents, Homozygote, lipoprotein, Antibodies, Monoclonal, Lipoproteins, LDL, Phenotype, Treatment Outcome, Liver, Apolipoprotein B-100, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Female, lipids (amino acids, peptides, and proteins), leucine, Cardiology and Cardiovascular Medicine, Adult, medicine.medical_specialty, Evinacumab, LDL, Hyperlipoproteinemia Type II, Internal medicine, cholesterol, LDL, medicine, Humans, Genetic Predisposition to Disease, angiopoietin-like protein, isotope, Angiopoietin-Like Protein 3, Catabolism, business.industry, Cholesterol, cholesterol, nutritional and metabolic diseases, Pennsylvania, medicine.disease, Angiopoietin-like Proteins, Endocrinology, Lipoproteins, IDL, Receptors, LDL, chemistry, Mutation, biology.protein, business, Biomarkers, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4dc1aa039b5083495d1d137d28d579Test
https://pure.amc.nl/en/publications/angptl3-inhibition-with-evinacumab-results-in-faster-clearance-of-idl-and-ldl-apob-in-patients-with-homozygous-familial-hypercholesterolemia--brief-reportTest(229b8efd-fcc3-485c-8d8f-449c0e5cbabd).html

المؤلفون: Cecilia Vitali, Donna M. Conlon, Nicholas J. Hand, Daniel J. Rader, John S. Millar, John W. Tobias, Katherine Quiroz-Figueroa, Robert C. Bauer

المصدر: J Clin Invest

مصطلحات موضوعية: Male, medicine.medical_specialty, Apolipoprotein B, Activating transcription factor, Protein Serine-Threonine Kinases, chemistry.chemical_compound, Mice, Downregulation and upregulation, Internal medicine, medicine, CCAAT-Enhancer-Binding Protein-alpha, Animals, Humans, Transcription factor, Apolipoproteins B, ATF3, Activating Transcription Factor 3, biology, Catabolism, Chemistry, Cholesterol, Intracellular Signaling Peptides and Proteins, General Medicine, Lipids, Lipoproteins, LDL, Mice, Inbred C57BL, Endocrinology, Receptors, LDL, LDL receptor, biology.protein, Hepatocytes, lipids (amino acids, peptides, and proteins), Female, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18132679d24d0dbc05a095e19a5b94dTest
https://pubmed.ncbi.nlm.nih.gov/34779419Test

المؤلفون: Björn Dahlbäck, Douglas L. Mann, Nancy K. Sweitzer, Dietmar A. Seiffert, David A. Gordon, Christina Chistoffersen, James C. Fang, Lei Zhao, Swapnil V. Shewale, Thomas P. Cappola, Luigi Adamo, Kenneth B. Margulies, Daniel J. Rader, Jeff Brandimarto, Ali Javaheri, John S. Millar, Bruce D. Car, Cecilia Frej, Julio A. Chirinos, Zhaoqing Wang, Yi Jia, John S. Parks, Benjamin French

المصدر: Circulation

مصطلحات موضوعية: Male, Proteomics, medicine.medical_specialty, Time Factors, Apolipoprotein B, Proteome, Adverse outcomes, Down-Regulation, Apolipoproteins M, 030204 cardiovascular system & hematology, Risk Assessment, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Sphingosine, Physiology (medical), Internal medicine, medicine, Humans, Sphingosine-1-phosphate, Registries, 030304 developmental biology, Aged, Randomized Controlled Trials as Topic, Heart Failure, 0303 health sciences, biology, business.industry, Human heart, Physical interaction, Middle Aged, medicine.disease, Prognosis, United States, Endocrinology, chemistry, Heart failure, biology.protein, lipids (amino acids, peptides, and proteins), Female, Lysophospholipids, Cardiology and Cardiovascular Medicine, business, Lipoproteins, HDL, Biomarkers, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77dad93a37229cba573a3b2ca81a57acTest
https://europepmc.org/articles/PMC7200273Test/

المؤلفون: Frederick Anokye-Danso, Naji Alamuddin, Sudipa Sarkar, Jena Shaw Tronieri, Rexford S. Ahima, John S. Millar, Thomas A. Wadden

المصدر: Obes Surg

مصطلحات موضوعية: Adult, medicine.medical_specialty, Sleeve gastrectomy, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Gastric Bypass, 030209 endocrinology & metabolism, medicine.disease_cause, Gastroenterology, Article, 03 medical and health sciences, 0302 clinical medicine, Gastrectomy, Internal medicine, Medicine, Humans, Postoperative Period, chemistry.chemical_classification, Nutrition and Dietetics, business.industry, Gastric bypass surgery, Insulin, Fatty Acids, Fatty acid, nutritional and metabolic diseases, Middle Aged, medicine.disease, Roux-en-Y anastomosis, Obesity, Obesity, Morbid, Treatment Outcome, chemistry, Case-Control Studies, 030211 gastroenterology & hepatology, Surgery, Female, business, Body mass index, Biomarkers, Polyunsaturated fatty acid, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb68a69f1b91a82afea964aff2fa7ccTest
https://europepmc.org/articles/PMC6920534Test/

المؤلفون: Patricia Jumes, Yang Liu, Thomas P. Roddy, Rajasekhar Ramakrishnan, Wahida Karmally, Gissette Reyes-Soffer, David E. Gutstein, Haihong Zhou, Stephen Holleran, John A. Wagner, Santica M. Marcovina, Amy O. Johnson-Levonas, John S. Millar, Daniel J. Rader, Brian K. Hubbard, Stephen F. Previs, Tiffany Thomas, Henry N. Ginsberg

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology

مصطلحات موضوعية: 0301 basic medicine, Male, Time Factors, Apolipoprotein B, Atorvastatin, 030204 cardiovascular system & hematology, Severity of Illness Index, chemistry.chemical_compound, 0302 clinical medicine, Interquartile range, Anacetrapib, Tandem Mass Spectrometry, cysteine, lipoprotein metabolism, Blood lipoproteins, biology, Chemistry, Anticholesteremic Agents, Lipoprotein(a), Middle Aged, inhibitor, Treatment Outcome, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Medicine, lipids (amino acids, peptides, and proteins), Female, Hypercholesteremia--Treatment, Cardiology and Cardiovascular Medicine, medicine.drug, ezetimibe, Adult, medicine.medical_specialty, Hypercholesterolemia, stable isotopes, Down-Regulation, Lipoproteins--Metabolism, Placebo, 03 medical and health sciences, Double-Blind Method, Internal medicine, Cholesterylester transfer protein, CETP, medicine, Humans, Oxazolidinones, Aged, lipoprotein (a), Pennsylvania, Cholesterol Ester Transfer Proteins, 030104 developmental biology, Endocrinology, biology.protein, anacetrapib, New York City, Lipoprotein A, kringle, Biomarkers, Lipoprotein, Clinical and Population Studies, Chromatography, Liquid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2ae6e707bffcfa7148a74b984400c9Test
http://europepmc.org/articles/PMC5567403Test

المؤلفون: Richard L. Dunbar, Todd G. Kirchgessner, Rahul Poria, Donna M. Conlon, Debra Cromley, Carol S. Ryan, Marina Cuchel, Amanda Baer, Jeffrey T. Billheimer, Daniel J. Rader, Sissel Lund-Katz, Richard Freifelder, Liming Qu, Anna Raper, Giancomo Ruotolo, John S. Millar, Ching-Chiang Su, Peter Åkerblad, Benjamin French, Xiaoyu Li, William Farver, Daniel A. Pryma, Lan Xiao

المصدر: Journal of Lipid Research, Vol 58, Iss 4, Pp 752-762 (2017)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Agonist, Adolescent, medicine.drug_class, QD415-436, 030204 cardiovascular system & hematology, Biology, Pharmacology, Biochemistry, Feces, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, In vivo, medicine, Animals, Humans, Distribution (pharmacology), Macrophage, Liver X receptor, Research Articles, Aged, Liver X Receptors, Macrophages, Cholesterol, HDL, Reverse cholesterol transport, Biological Transport, Cell Biology, Mononuclear phagocyte system, Middle Aged, Atherosclerosis, lipoproteins, Cholesterol, 030104 developmental biology, Liver, chemistry, high density lipoprotein, Immunology, Cholesteryl ester, Nanoparticles, Female, lipids (amino acids, peptides, and proteins), Lipoproteins, HDL

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a62d8e481687a201a84014e01be9e8cTest
https://doi.org/10.1194/jlr.m075226Test

المؤلفون: Micah Romer, Judith B. Grinspan, John S. Millar, Brigid K. Jensen, Sangwon F. Kim, Hubert Monnerie, Kelly L. Jordan-Sciutto

المصدر: Journal of Neurochemistry. 140:53-67

مصطلحات موضوعية: Male, 0301 basic medicine, Pyrrolidines, Cellular differentiation, digestive system, Biochemistry, Article, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Myelin, 0302 clinical medicine, polycyclic compounds, medicine, Animals, Transcription factor, Cells, Cultured, Sterol Regulatory Element Binding Proteins, biology, Serine Endopeptidases, Oligodendrocyte differentiation, food and beverages, Cell Differentiation, Lipid metabolism, Oligodendrocyte, Sterol regulatory element-binding protein, Myelin basic protein, Oligodendroglia, 030104 developmental biology, medicine.anatomical_structure, Animals, Newborn, biology.protein, Female, lipids (amino acids, peptides, and proteins), Proprotein Convertases, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ca8bb19756e3da3c613b84e0559c7dTest
https://doi.org/10.1111/jnc.13721Test

المؤلفون: Patricia Jumes, Rajasekhar Ramakrishnan, Stephen Holleran, John S. Millar, Gissette Reyes-Soffer, Amanda Baer, Yang Liu, Henry N. Ginsberg, Tiffany Thomas, David E. Gutstein, John A. Wagner, Amy O. Johnson-Levonas, Richard L. Dunbar, Emil M. deGoma, Daniel J. Rader, Michael E. Lassman, Wahida Karmally, Colleen Ngai, Ellie Coromilas, Hashmi Rafeek, Daniel S. Donovan, Bela F. Asztalos

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 36:994-1002

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Time Factors, Apolipoprotein B, Atorvastatin, 030204 cardiovascular system & hematology, Fractional clearance, 03 medical and health sciences, Plasma Cholesteryl Ester Transfer Protein, chemistry.chemical_compound, 0302 clinical medicine, High-density lipoprotein, Double-Blind Method, Anacetrapib, Internal medicine, Cholesterylester transfer protein, medicine, Humans, Oxazolidinones, Aged, Dyslipidemias, Apolipoprotein A-I, biology, Chemistry, Anticholesteremic Agents, nutritional and metabolic diseases, Metabolism, Middle Aged, Cholesterol Ester Transfer Proteins, Treatment Outcome, 030104 developmental biology, Endocrinology, biology.protein, Female, lipids (amino acids, peptides, and proteins), Lipoproteins, HDL, Cardiology and Cardiovascular Medicine, Apolipoprotein A-II, Biomarkers, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf3cf00e2c4eb5ab94d48623a1918bfTest
https://doi.org/10.1161/atvbaha.115.306680Test

المؤلفون: Hanrui Zhang, Edward E. Morrisey, Sager J. Gosai, Kate Bermingham, Christine C. Hinkle, Muredach P. Reilly, Evanthia E. Pashos, Marina Cuchel, Wenjun Li, John S. Millar, Ruilan Yan, Stella T. Chou, Ying Liu, Jennifer Tabita-Martinez, Chenyi Xue, Amrith Rodrigues, Wenli Yang, Daniel J. Rader, Daniel VanDorn, Rhia Shah, Mingyao Li, Brian D. Gregory

المصدر: Circulation Research. 117:17-28

مصطلحات موضوعية: Adult, Lipopolysaccharides, Male, Genotype, Lipopolysaccharide, Physiology, Phagocytosis, Induced Pluripotent Stem Cells, Molecular Sequence Data, Cell Culture Techniques, Macrophage polarization, Biology, Article, Proinflammatory cytokine, Transcriptome, Interferon-gamma, Mice, Young Adult, chemistry.chemical_compound, Sequence Homology, Nucleic Acid, Animals, Humans, Secretion, RNA, Messenger, Induced pluripotent stem cell, Cells, Cultured, Embryoid Bodies, Tangier Disease, Aged, Inflammation, Mice, Knockout, Base Sequence, Macrophages, Cell Differentiation, Macrophage Activation, Antigens, Differentiation, Cell biology, Cholesterol, Phenotype, chemistry, Immunology, Female, Efflux, Cardiology and Cardiovascular Medicine, Sequence Alignment, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acc90169da44c924681263b248a1987Test
https://doi.org/10.1161/circresaha.117.305860Test