المؤلفون: Myrna C.B. Godoy, Jean Pierre J. Issa, Hoa H.N. Pham, Humam Kadara, Alexandre Reuben, Paul Scheet, Ignacio I. Wistuba, Dan Su, Ara A. Vaporciyan, Chi Wan Chow, P. Andrew Futreal, Xin Hu, Runzhe Chen, Linghua Wang, Lisha Ying, J. Jack Lee, Jianhua Zhang, Boris Sepesi, Harvey I. Pass, John V. Heymach, Jian Carrot-Zhang, Carmen Behrens, Junya Fujimoto, Junya Fukuoka, Marcos R. Estecio, Jianjun Zhang, Brett W. Carter, Nicholas McGranahan, Yue Lu, Mara B. Antonoff

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: Male, Epigenomics, 0301 basic medicine, Lung Neoplasms, Carcinogenesis, General Physics and Astronomy, medicine.disease_cause, Epigenome, 0302 clinical medicine, Mutation Rate, Chromosome instability, Tumor Microenvironment, Cancer genomics, Copy-number variation, Lung, Aged, 80 and over, Mutation, Multidisciplinary, Methylation, Middle Aged, 030220 oncology & carcinogenesis, Reduced representation bisulfite sequencing, DNA methylation, Disease Progression, Adenocarcinoma, Female, Adult, DNA Copy Number Variations, Tumour heterogeneity, Science, Adenocarcinoma of Lung, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Genetic Heterogeneity, 03 medical and health sciences, Chromosomal Instability, medicine, Humans, Atypical adenomatous hyperplasia, Aged, Hyperplasia, General Chemistry, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Mutagenesis, Cancer research, Precancerous Conditions, Non-small-cell lung cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28d5ae9768cd6c19fb4d9d6edb29718Test
https://doaj.org/article/031719f1a9f8488a91a5917acd62743fTest

المؤلفون: Carmen Sapienza, Kelsey Keith, Jean Pierre J. Issa, Jozef Madzo, Shoghag Panjarian, Carolyn M. Slater, Jaroslav Jelinek

المصدر: Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Aging, Breast Neoplasms, Biology, Malignant transformation, 03 medical and health sciences, chemistry.chemical_compound, Epigenome, 0302 clinical medicine, Breast cancer, Surgical oncology, Predicted age, Internal medicine, medicine, Outliers, Humans, Breast, RC254-282, 030304 developmental biology, 0303 health sciences, DNA methylation, Cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Methylation, medicine.disease, Phenotype, chemistry, 030220 oncology & carcinogenesis, CpG Islands, Female, Accelerated aging, DNA, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6fcd46e10aafa0cc4ca67da20fde2eTest
http://europepmc.org/articles/PMC8140515Test

المؤلفون: Mohammad Azab, Scott D. Lunin, Patricia Kropf, Nikolai A. Podoltsev, Jesus G. Berdeja, Michael R. Savona, Todd L. Rosenblat, Harold N. Keer, Hagop M. Kantarjian, Katherine Walsh, Guillermo Garcia-Manero, Wendy Stock, Elias Jabbour, Raoul Tibes, Jean Pierre J. Issa, Karen Yee, Joseph R. Mace, Ellen K. Ritchie, Elizabeth A. Griffiths, Casey O'Connell, Gail J. Roboz, Yong Hao

المصدر: The Lancet Haematology. 6:e317-e327

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Neutropenia, Adolescent, Decitabine, Antineoplastic Agents, Severity of Illness Index, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Humans, Adverse effect, Survival rate, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Hematology, Middle Aged, medicine.disease, Thrombocytopenia, Survival Rate, Treatment Outcome, Tolerability, Hypomethylating agent, International Prognostic Scoring System, Myelodysplastic Syndromes, 030220 oncology & carcinogenesis, Azacitidine, Female, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d3a14be9a90c2cbe74c5f5714074dTest
https://doi.org/10.1016/s2352-3026Test(19)30029-8

المؤلفون: Charly R. Good, Andrew Kelly, Jozef Madzo, Jean Pierre J. Issa, Patricia Kropf, Priyanka Madireddi, Jaroslav Jelinek

المصدر: Leukemia

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, NPM1, Biology, Article, Epigenesis, Genetic, 03 medical and health sciences, AML, medicine, Humans, DNA (Cytosine-5-)-Methyltransferases, DMP, Epigenetics, Aged, Aged, 80 and over, DNA methylation, CIMP, Cytogenetics, Nuclear Proteins, demethylation, Myeloid leukemia, Hematology, Middle Aged, Prognosis, Phenotype, Up-Regulation, 3. Good health, Leukemia, Myeloid, Acute, 030104 developmental biology, fms-Like Tyrosine Kinase 3, Oncology, CpG site, Mutation, Fms-Like Tyrosine Kinase 3, Cancer research, DNMT3A, CpG Islands, Female, Nucleophosmin, hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e406302f22dd4376a5c76741af9c5a4bTest
https://doi.org/10.1038/s41375-018-0084-2Test

المؤلفون: Yue Lu, Ricki J. Colman, Jozef Madzo, Jean Pierre J. Issa, Jaroslav Jelinek, Shoudan Liang, Shinji Maegawa, Justin T. Lee, Tomomitsu Tahara

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Aging, Adolescent, Science, Longevity, General Physics and Astronomy, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Epigenesis, Genetic, 03 medical and health sciences, Mice, Internal medicine, Age related, Gene expression, medicine, Animals, Humans, Epigenetics, Child, lcsh:Science, Epigenesis, Aged, Caloric Restriction, Genetics, Regulation of gene expression, Aged, 80 and over, Multidisciplinary, Infant, Newborn, Caloric theory, Infant, General Chemistry, Methylation, DNA Methylation, Middle Aged, Macaca mulatta, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Child, Preschool, DNA methylation, Female, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10213650dd6d5a10433df4d58d584f00Test
https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a2Test

المؤلفون: Jean Pierre J. Issa, Rosalind A. Eeles, Rayjean J. Hung, Ellen L. Goode, Yesilda Balavarca, Dominique Scherer, Xifeng Wu, Aditi Hazra, Reka Toth, Yuanqing Ye, Shuji Ogino, Cornelia M. Ulrich, Victor Moreno, Linda E. Kelemen, Angela Risch

المصدر: Cancer Epidemiology, Biomarkers & Prevention. 26:816-825

مصطلحات موضوعية: Epigenomics, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Candidate gene, Epidemiology, Estrogen receptor, Single-nucleotide polymorphism, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Neoplasms, Internal medicine, Genotype, medicine, Humans, Epigenetics, Genetic Variation, Cancer, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d528382b81e99826b7fa50acb92057c3Test
https://doi.org/10.1158/1055-9965.epi-16-0728Test

المؤلفون: Jean Pierre J. Issa, Hagop M. Kantarjian, Jaroslav Jelinek, Henry C. Fung, Mohammad Azab, Patricia Kropf, Woonbok Chung, Xiang Yao Su, Gail J. Roboz, Andrew Kelly

المصدر: Clinical Epigenetics

مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Male, medicine.disease_cause, 0302 clinical medicine, AML, CDKN2B, Genetics (clinical), Aged, 80 and over, Myeloid leukemia, Genomics, Guadecitabine, Middle Aged, 3. Good health, Leukemia, Leukemia, Myeloid, Acute, Treatment Outcome, 030220 oncology & carcinogenesis, DNA methylation, Azacitidine, Female, KRAS, Mutations, Adult, medicine.medical_specialty, DNA methyltransferase, 03 medical and health sciences, Young Adult, DNA methylation inhibitor, Internal medicine, Genetics, medicine, Biomarkers, Tumor, Humans, Molecular Biology, Survival rate, Aged, business.industry, Research, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Drug resistance, Mutation, Gene expression, Neoplasm Recurrence, Local, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba87adcbd903da019b3a83670791cfaTest
http://europepmc.org/articles/PMC6647096Test

المؤلفون: Elisabetta Lauretti, Jean Pierre J. Issa, Antonio Di Meco, Domenico Praticò, Mary Elizabeth Curtis, Jaroslav Jelinek

المصدر: Molecular psychiatry

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Disease, memory, Mice, 0302 clinical medicine, Pregnancy, synapse, tau, Brain Diseases, high fat diet, Brain, FOXP2, Forkhead Transcription Factors, Amyloidosis, Up-Regulation, Psychiatry and Mental health, In utero, Gestation, Female, Alzheimer’s disease, medicine.medical_specialty, Offspring, Transgene, Mice, Transgenic, tau Proteins, Neuropathology, transgenic mice, Diet, High-Fat, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Downregulation and upregulation, Alzheimer Disease, Internal medicine, medicine, Animals, Genetic Predisposition to Disease, Molecular Biology, Memory Disorders, Amyloid beta-Peptides, business.industry, Repressor Proteins, amyloid beta, Disease Models, Animal, maternal, 030104 developmental biology, Endocrinology, Synapses, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d994671656fb0255c5a192a6c86689aTest
https://pubmed.ncbi.nlm.nih.gov/31451749Test

المؤلفون: Elias J. Jabbour, Katherine Walsh, Pietro Taverna, Yong Hao, Wendy Stock, Jean Pierre J. Issa, Woonbok Chung, James N. Lowder, David A. Rizzieri, Elizabeth A. Griffiths, Casey O'Connell, Gail J. Roboz, Aram Oganesian, Karen Yee, Mohammad Azab, Sue Naim, Hagop M. Kantarjian, Raoul Tibes, Naval Daver

المصدر: The Lancet Oncology. 16:1099-1110

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Maximum Tolerated Dose, Azacitidine, Decitabine, Gastroenterology, Disease-Free Survival, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aged, Neoplasm Staging, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Standard treatment, Middle Aged, Prognosis, medicine.disease, Effective dose (pharmacology), Leukemia, Myeloid, Acute, Regimen, Oncology, Tolerability, Myelodysplastic Syndromes, Immunology, Female, business, Febrile neutropenia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf7f6496beb4b783b51523e78219598Test
https://doi.org/10.1016/s1470-2045Test(15)00038-8

المؤلفون: Andrew Kelly, Jean Pierre J. Issa, Bela Patel, Jozef Madzo, Charly R. Good, Shoghag Panjarian, Jaroslav Jelinek

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Carcinogenesis, Triple Negative Breast Neoplasms, Biology, Article, Mixed Function Oxygenases, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Humans, Triple-negative breast cancer, PI3K/AKT/mTOR pathway, Cell Proliferation, Regulation of gene expression, Oncogene, TOR Serine-Threonine Kinases, Cancer, Oncogenes, DNA Methylation, medicine.disease, Up-Regulation, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, CpG site, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, CpG Islands, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91bed41eff5d2e5945a010bc6fb267cTest
https://europepmc.org/articles/PMC6072603Test/