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المؤلفون: Jan Spaas, Richie P. Goulding, Charly Keytsman, Lena Fonteyn, Jack van Horssen, Richard T. Jaspers, Bert O. Eijnde, Rob C.I. Wüst
المساهمون: Physiology, AMS - Musculoskeletal Health, AMS - Rehabilitation & Development, AMS - Tissue Function & Regeneration, AMS - Ageing & Vitality, Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, SPAAS, Jan/0000-0002-4953-2505, SPAAS, Jan, Goulding, Richie P., KEYTSMAN, Charly, FONTEYN, Lena, VAN HORSSEN, Jack, Jaspers, Richard T., OP 'T EIJNDE, Bert, Wust, Rob C. I.
المصدر: Journal of Cachexia, Sarcopenia and Muscle, 13(5), 2537-2550. Springer Verlag
Spaas, J, Goulding, R P, Keytsman, C, Fonteyn, L, van Horssen, J, Jaspers, R T, Eijnde, B O & Wüst, R C I 2022, ' Altered muscle oxidative phenotype impairs exercise tolerance but does not improve after exercise training in multiple sclerosis ', Journal of Cachexia, Sarcopenia and Muscle, vol. 13, no. 5, pp. 2537-2550 . https://doi.org/10.1002/jcsm.13050Test
Journal of Cachexia, Sarcopenia and Muscle, 13(5), 2537-2550. Wiley-Blackwell
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLEمصطلحات موضوعية: Male, Exercise Tolerance, Exercise therapy, Skeletal muscle, Mitochondria, Oxygen, PPAR gamma, Succinate Dehydrogenase, Multiple sclerosis, Oxidative Stress, Oxygen Consumption, Phenotype, Physiology (medical), Medicine and Health Sciences, Quality of Life, Exercise capacity, Humans, Oxidative metabolism, Orthopedics and Sports Medicine, Female, Muscle, Skeletal, Exercise
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1543ade4c1fc23b89d4d1c8877495b5eTest
https://research.vu.nl/en/publications/d83bcb73-ed93-448a-b82b-8363e62feb5eTest -
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المؤلفون: Sina C. Rosenkranz, Simone Bauer, Charlotte Schubert, Jan Broder Engler, Simone Träger, Celina Schwencke-Westphal, Nanne Paauw, Artem A Shaposhnykov, Marc Freichel, Benjamin Schattling, Vanessa Roth, Jack van Horssen, Manuel A. Friese, Vanessa Vieira, Lukas Can Bal, Ole Pless, Maarten E. Witte
المساهمون: Molecular cell biology and Immunology, AII - Inflammatory diseases, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, Publica
المصدر: eLife
eLife, 10:e61798, 1-60. eLife Sciences Publications Limited
eLife, Vol 10 (2021)
Rosenkranz, S C, Shaposhnykov, A A, Traeger, S, Engler, J B, Witte, M E, Roth, V, Vieira, V, Paauw, N, Bauer, S, Schwencke-Westphal, C, Schubert, C, Bal, L C, Schattling, B, Pless, O, van Horssen, J, Freichel, M & Friese, M A 2021, ' Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis ', eLife, vol. 10, e61798, pp. 1-60 . https://doi.org/10.7554/eLife.61798Test, https://doi.org/10.7554/eLife.61798Testمصطلحات موضوعية: 0301 basic medicine, Male, Mitochondrial DNA, Multiple Sclerosis, Ppargc1a, Mouse, QH301-705.5, Science, Calcium buffering, oxidative phosphorylation, Inflammation, Biology, Mitochondrion, Neuroprotection, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Immunology and Inflammation, medicine, Animals, Biology (General), Neurons, General Immunology and Microbiology, EAE, General Neuroscience, Experimental autoimmune encephalomyelitis, Neurodegeneration, General Medicine, medicine.disease, Cell biology, Mitochondria, Disease Models, Animal, 030104 developmental biology, Medicine, neuroprotection, Female, PPARGC1A, medicine.symptom, 030217 neurology & neurosurgery, Research Article, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8d3e60a01db468e5ad64f4d602f157Test
https://doi.org/10.7554/elife.61798Test -
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المؤلفون: Niels Hellings, Jeroen F. J. Bogie, Bert O. Eijnde, Bieke Broux, Shahid P Baba, Dheeraj Kumar Posa, Charly Keytsman, Tim Vanmierlo, Laura Blancquaert, Wouter M. A. Franssen, David Hoetker, Jack van Horssen, Wim Derave, Jan H. Spaas
المساهمون: SPAAS, Jan/0000-0002-4953-2505, RS: MHeNs - R3 - Neuroscience, Psychiatrie & Neuropsychologie, Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: JOURNAL OF NEUROINFLAMMATION
Journal of Neuroinflammation, 18(1):255. BioMed Central Ltd
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Journal of Neuroinflammation, 18(1):255. BioMed Central
Spaas, J, Franssen, W M A, Keytsman, C, Blancquaert, L, Vanmierlo, T, Bogie, J, Broux, B, Hellings, N, van Horssen, J, Posa, D K, Hoetker, D, Baba, S P, Derave, W & Eijnde, B O 2021, ' Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation ', Journal of Neuroinflammation, vol. 18, no. 1, 255 . https://doi.org/10.1186/s12974-021-02306-9Test
Journal of Neuroinflammationمصطلحات موضوعية: Male, Acrolein, Carnosine, Multiple sclerosis, Neuroinflammation, Oxidative, Pharmacology, medicine.disease_cause, SUPPLEMENTATION, Mice, chemistry.chemical_compound, Reactive carbonyl, CHEMISTRY, Medicine and Health Sciences, PROTEIN CARBONYLATION, DAMAGE, Microglia, General Neuroscience, Experimental autoimmune encephalomyelitis, MULTIPLE-SCLEROSIS, medicine.anatomical_structure, Neurology, Female, medicine.symptom, Encephalomyelitis, Autoimmune, Experimental, Immunology, Inflammation, Nitric oxide, stress, Cellular and Molecular Neuroscience, Autoimmune Diseases of the Nervous System, medicine, Animals, Humans, TRANSCRIPTOME, RC346-429, DETOXIFICATION, Research, Biology and Life Sciences, HISTIDINE-CONTAINING DIPEPTIDES, medicine.disease, Mice, Inbred C57BL, chemistry, Oxidative stress, Neuroinflammatory Diseases, CELLS, Neurology. Diseases of the nervous system
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10493d5b0217197873f415df24e8fa39Test
http://www.scopus.com/inward/record.url?scp=85118759302&partnerID=8YFLogxKTest -
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المؤلفون: Sabela Rodríguez-Lorenzo, Susanne M. A. van der Pol, Helga E. de Vries, Sandra Amor, Maarten E. Witte, Jack van Horssen, Julia Konings, Gijs Kooij, Alwin Kamermans
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Pathology, AII - Inflammatory diseases, ACS - Microcirculation
المصدر: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Acta Neuropathologica Communications
Rodríguez-Lorenzo, S, Konings, J, Van Der Pol, S, Kamermans, A, Amor, S, Van Horssen, J, Witte, M, Kooij, G & De Vries, H E 2020, ' Inflammation of the choroid plexus in progressive multiple sclerosis : Accumulation of granulocytes and T cells ', Acta neuropathologica communications, vol. 8, no. 1, 9 . https://doi.org/10.1186/s40478-020-0885-1Test
Acta neuropathologica communications, 8(1):9. BioMed Centralمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Stromal cell, T-Lymphocytes, Central nervous system, T cells, Inflammation, Choroid plexus, Biology, lcsh:RC346-429, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cerebrospinal fluid, Immune system, medicine, Humans, lcsh:Neurology. Diseases of the nervous system, Aged, Aged, 80 and over, B-Lymphocytes, Progressive MS, Macrophages, Research, Multiple sclerosis, Immune cells, Correction, Dendritic Cells, Middle Aged, Multiple Sclerosis, Chronic Progressive, medicine.disease, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, Blood-CSF barrier, Immunology, Female, Neurology (clinical), medicine.symptom, 030217 neurology & neurosurgery, CD8, Granulocytes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa17b7122b5c306945ca18a22660462Test
https://doaj.org/article/8c7ddcfe2bec45a086daa724750ab49dTest -
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المؤلفون: Lydian Knoop, Alwin Kamermans, Susanne M. A. van der Pol, Svenja Kiljan, Marc Franssen, Geert J. Schenk, Carmen Picón, Jack van Horssen, Evelien Drost, Nicholas D. Mazarakis, Sandra Amor, Lynn van Olst, Richard Reynolds, Helga E. de Vries, Rachel E. James, Maarten E. Witte, Iliana Michailidou, Jeroen J. G. Geurts, Carla Rodriguez-Mogeda
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Anatomy and neurosciences, Amsterdam Neuroscience - Neurodegeneration, Pathology, AII - Inflammatory diseases, ACS - Microcirculation, Amsterdam Neuroscience - Neurovascular Disorders
المصدر: Acta Neuropathologica, 141(6), 881-899. Springer Verlag
van Olst, L, Rodriguez Mogeda, C, Picon, C, Kiljan, S, James, R E, Kamermans, A, van der Pol, S M A, Knoop, L, Michailidou, I, Drost, E, Franssen, M, Schenk, G J, Geurts, J J G, Amor, S, Mazarakis, N D, van Horssen, J, de Vries, H E, Reynolds, R & Witte, M E 2021, ' Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration ', Acta Neuropathologica, vol. 141, no. 6, pp. 881-899 . https://doi.org/10.1007/s00401-021-02293-4Test
Acta Neuropathologicaمصطلحات موضوعية: Adult, Programmed cell death, Multiple Sclerosis, Population, Inflammation, Biology, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Meninges, Neuroinflammation, Cortex (anatomy), medicine, Animals, Humans, Neurodegeneration, education, Aged, Cerebral Cortex, Neurons, Original Paper, education.field_of_study, Cell Death, Microglia, Multiple sclerosis, Neurodegenerative Diseases, Middle Aged, medicine.disease, Rats, Cortical pathology, Disease Models, Animal, Phenotype, medicine.anatomical_structure, nervous system, Neuroinflammatory Diseases, Female, Neurology (clinical), medicine.symptom, Neuroscience, Demyelinating Diseases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0957b67feeac3b0e4dfd13e8b3902887Test
https://research.vumc.nl/en/publications/1f92b2d0-c8fa-4105-bbe6-f8f866702a82Test -
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المؤلفون: Philip Scheltens, Charlotte E. Teunissen, Victor L. Thijssen, Ananya Chakraborty, Ruud D. Fontijn, Alwin Kamermans, Ed Aanhane, Bert van het Hof, Jack van Horssen, Kitty C. M. Castricum, Wiesje M. van der Flier, Helga E. de Vries
المساهمون: Molecular cell biology and Immunology, Medical oncology laboratory, Radiation Oncology, Neurology, Clinical chemistry, Amsterdam Neuroscience - Neurovascular Disorders, APH - Personalized Medicine, APH - Methodology, Epidemiology and Data Science, ACS - Microcirculation
المصدر: Chakraborty, A, Kamermans, A, van Het Hof, B, Castricum, K, Aanhane, E, van Horssen, J, Thijssen, V L, Scheltens, P, Teunissen, C E, Fontijn, R D, van der Flier, W M & de Vries, H E 2018, ' Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy ', Brain : a journal of neurology, vol. 141, no. 12, pp. 3377-3388 . https://doi.org/10.1093/brain/awy274Test
Brain : a journal of neurology, 141(12), 3377-3388مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Angiopoietin-like 4 Protein, Vascular Remodeling, Blood–brain barrier, Vascular remodelling in the embryo, Angiopoietin, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Angiopoietin-Like Protein 4, Humans, Medicine, Vascular dementia, Aged, Aged, 80 and over, business.industry, Brain, Endothelial Cells, Human brain, medicine.disease, Cell Hypoxia, Endothelial stem cell, Cerebral Amyloid Angiopathy, 030104 developmental biology, medicine.anatomical_structure, Astrocytes, Microvessels, Female, Neurology (clinical), Cerebral amyloid angiopathy, business, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b850238bc9029d2faf99131bddf794dTest
https://doi.org/10.1093/brain/awy274Test -
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المؤلفون: Rachel James, Richard Reynolds, Anusha Jayaraman, Carmen Picón, Patricia Gallego, Jack van Horssen, Catriona Beck, Maarten E. Witte, Nicholas D. Mazarakis
المساهمون: Molecular cell biology and Immunology, AII - Inflammatory diseases, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, Multiple Sclerosis Society, National Multiple Sclerosis Society, Medical Research Council (MRC)
المصدر: Acta Neuropathologica
Acta Neuropathologica, 141(4), 585-604. Springer Verlag
Picon, C, Jayaraman, A, James, R, Beck, C, Gallego, P, Witte, M E, van Horssen, J, Mazarakis, N D & Reynolds, R 2021, ' Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter ', Acta Neuropathologica, vol. 141, no. 4, pp. 585-604 . https://doi.org/10.1007/s00401-021-02274-7Test, https://doi.org/10.1007/s00401-021-02274-7Testمصطلحات موضوعية: Adult, Male, Necroptosis, Clinical Neurology, Apoptosis, Grey matter, Receptors, Tumor Necrosis Factor, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, RIPK1, Meninges, Pathology, medicine, Animals, Humans, FADD, Gray Matter, Neurodegeneration, Aged, Cerebral Cortex, Neurons, Original Paper, Science & Technology, Neurology & Neurosurgery, biology, Tumor Necrosis Factor-alpha, Neurosciences, 1103 Clinical Sciences, Middle Aged, Multiple Sclerosis, Chronic Progressive, medicine.disease, Cell biology, Rats, medicine.anatomical_structure, biology.protein, Cytokines, Tumor necrosis factor alpha, Female, Neurosciences & Neurology, Neurology (clinical), Neuron, Signal transduction, 1109 Neurosciences, Life Sciences & Biomedicine, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a1efddbfaa635db122af5a7ce2e3f5Test
https://pubmed.ncbi.nlm.nih.gov/33569629Test -
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المؤلفون: Maarten E. Witte, Tom Verhoeven, Jasper J. Koning, Jack van Horssen, Bert van het Hof, Lauri Borghuis, Merel Rijnsburger, Alwin Kamermans, Helga E. de Vries
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, ACS - Microcirculation
المصدر: Kamermans, A, Verhoeven, T, van het Hof, B, Koning, J J, Borghuis, L, Witte, M, van Horssen, J, de Vries, H E & Rijnsburger, M 2019, ' Setmelanotide, a Novel, Selective Melanocortin Receptor-4 Agonist Exerts Anti-inflammatory Actions in Astrocytes and Promotes an Anti-inflammatory Macrophage Phenotype ', Frontiers in Immunology, vol. 10, 2312 . https://doi.org/10.3389/fimmu.2019.02312Test
Frontiers in Immunology, 10:2312
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunologyمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Agonist, lcsh:Immunologic diseases. Allergy, medicine.drug_class, Immunology, Anti-Inflammatory Agents, macrophage, multiple sclerosis, Neuroprotection, 03 medical and health sciences, 0302 clinical medicine, astrocyte, Melanocortin receptor, medicine, Humans, Immunology and Allergy, melanocortin, Phosphorylation, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, Original Research, Aged, melanocortin receptor-4, Interleukin-6, Chemistry, Macrophages, Neurodegeneration, Interleukin, Middle Aged, Interleukin-11, medicine.disease, Melanocortin 4 receptor, Phenotype, 030104 developmental biology, medicine.anatomical_structure, alpha-MSH, inflammation, Astrocytes, Cancer research, Receptor, Melanocortin, Type 4, Female, Melanocortin, lcsh:RC581-607, 030215 immunology, Astrocyte
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b17f5ae96d8db4852179819d9bb35Test
https://research.vumc.nl/en/publications/ca4f60ca-aecc-435f-9bd3-00a1d1002c6aTest -
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المؤلفون: Cyra E. Leurs, Fredrik Piehl, Martijn D. Steenwijk, Lisanne J. Balk, Petar Podlesniy, Jack van Horssen, Joep Killestein, Bernard M. J. Uitdehaag, Arjan Malekzadeh, Ramon Trullas, Charlotte E. Teunissen
المساهمون: Neurology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Anatomy and neurosciences, Clinical chemistry, Molecular cell biology and Immunology, Ministerio de Economía y Competitividad (España), Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España)
المصدر: Multiple Sclerosis, 24(4), 472-480. SAGE Publications Ltd
Leurs, C E, Podlesniy, P, Trullas, R, Balk, L, Steenwijk, M D, Malekzadeh, A, Piehl, F, Uitdehaag, B M, Killestein, J, van Horssen, J & Teunissen, C E 2018, ' Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment ', Multiple Sclerosis, vol. 24, no. 4, pp. 472-480 . https://doi.org/10.1177/1352458517699874Test
Digital.CSIC. Repositorio Institucional del CSIC
instname
Multiple Sclerosis (Houndmills, Basingstoke, England)مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Mitochondrial DNA, Pathology, medicine.medical_specialty, Multiple Sclerosis, mitochondrial DNA, Disease, Mitochondrion, DNA, Mitochondrial, cerebrospinal fluid, Multiple sclerosis, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, 0302 clinical medicine, Cerebrospinal fluid, Humans, Medicine, Digital polymerase chain reaction, digital PCR, business.industry, biomarkers, Middle Aged, Multiple Sclerosis, Chronic Progressive, Clinical disease, medicine.disease, Mitochondria, 030104 developmental biology, Neurology, Feature (computer vision), Disease Progression, Female, Neurology (clinical), business, Original Research Papers, Digital PCR, Biomarkers, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97236814d071b50e0db7c4c6f9bc29a6Test
https://doi.org/10.1177/1352458517699874Test -
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المؤلفون: Ellen Boelen, Peter Delputte, Dirk Elewaut, Jack van Horssen, Els Louagie, Niels Hellings, Jerome Hendriks, Jeroen F. J. Bogie
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: Multiple Sclerosis, 24(3), 290-300. SAGE Publications Ltd
Bogie, J F, Boelen, E, Louagie, E, Delputte, P, Elewaut, D, van Horssen, J, Hendriks, J J & Hellings, N 2018, ' CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis ', Multiple Sclerosis, vol. 24, no. 3, pp. 290-300 . https://doi.org/10.1177/1352458517698759Test
Multiple sclerosis: clinical and laboratory researchمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Sialic Acid Binding Ig-like Lectin 1, Highly pathogenic, EAE, microglia, monocytes, neuroinflammation, sialoadhesin, CD169, Siglec-1, multiple sclerosis, Mice, 03 medical and health sciences, Sialoadhesin, Animals, Humans, Medicine, Pathophysiology of multiple sclerosis, Biology, Neuroinflammation, Aged, Inflammation, Phagocytes, Microglia, business.industry, Effector, Multiple sclerosis, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, Immunology, Female, Human medicine, Neurology (clinical), business, Engineering sciences. Technology, Biomarkers
وصف الملف: application/pdf; pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c00499d0495531fe30bb7526d6bff9aTest
https://doi.org/10.1177/1352458517698759Test
