Short-term very low calorie diet reduces oxidative stress in obese type 2 diabetic patients
| العنوان: | Short-term very low calorie diet reduces oxidative stress in obese type 2 diabetic patients |
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| المؤلفون: | Skrha, J., Kunesova, M., Hilgertova, J., Weiserova, H., Krizova, J., Eva Kotrlikova |
| المصدر: | Scopus-Elsevier ResearcherID |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Adult, Male, Physiology, Superoxide Dismutase, alpha-Tocopherol, Pilot Projects, General Medicine, Ascorbic Acid, Middle Aged, Oxidative Stress, Diabetes Mellitus, Type 2, Malondialdehyde, Humans, Female, Obesity, Biomarkers, Aged, Caloric Restriction |
| الوصف: | Oxidative stress is higher in obese diabetic than in non-diabetic subjects. This pilot study evaluates oxidative stress during short-term administration of a very low calorie diet in obese persons. Nine obese Type 2 diabetic patients (age 55+/-5 years, BMI 35.9+/-1.9 kg/m2) and nine obese non-diabetic control subjects (age 52+/-6 years, BMI 37.3+/-2.1 kg/m2) were treated by a very low calorie diet (600 kcal daily) during 8 days stay in the hospital. Serum cholesterol, triglycerides, non-esterified fatty acids (NEFA), beta-hydroxybutyrate (B-HB), ascorbic acid (AA), alpha-tocopherol (AT), plasma malondialdehyde (MDA) and superoxide dismutase (SOD) activity in erythrocytes were measured before and on day 3 and 8 of very low calorie diet administration. A decrease of serum cholesterol and triglyceride concentrations on day 8 was associated with a significant increase of NEFA (0.30+/-0.13 vs. 0.47+/-0.11 micromol/l, p |
| تدمد: | 0862-8408 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ffdfc9317acfac5bb8cf22593d8f64Test https://pubmed.ncbi.nlm.nih.gov/15717839Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20ffdfc9317acfac5bb8cf22593d8f64 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 08628408 |
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