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1
المؤلفون: Todd M. Bauer, Volker Wacheck, Evan W. Alley, Suhyun Kang, Sophie Callies, Anna M. Szpurka, Johanna C. Bendell, Melinda D. Willard, Anna M. Varghese, Marjorie G Zauderer, Enrica Capelletto
المصدر: Investigational New Drugs
مصطلحات موضوعية: 0301 basic medicine, Mesothelioma, Male, medicine.medical_specialty, Nausea, Pyridines, Antineoplastic Agents, Quinolones, Gastroenterology, LY3023414, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Phase I Studies, medicine, Humans, Pharmacology (medical), Adverse effect, Aged, Phosphoinositide-3 Kinase Inhibitors, Pharmacology, Aged, 80 and over, Solid tumor, Dose-Response Relationship, Drug, business.industry, TOR Serine-Threonine Kinases, PI3K/mTOR inhibitor, Middle Aged, medicine.disease, 030104 developmental biology, Treatment Outcome, Oncology, Tolerability, 030220 oncology & carcinogenesis, Cohort, Vomiting, Peritoneal mesothelioma, Female, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b31757deece1206395f11e99c740ec7Test
http://europepmc.org/articles/PMC8280020Test -
2
المؤلفون: Xuejing Wang, Katherine M Bell-McGuinn, Jimmy Hwang, Johanna C. Bendell, Hans Christian Reinhardt, Daphne L. Farrington, Celine Pitou, Helge Bischoff, Robert M. Campbell, Thomas Zander, Scott M. Hynes, Philip W. Iversen, Michael Thomas
المصدر: Investigational New Drugs. 38:1145-1155
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Pyridines, Population, Antineoplastic Agents, Models, Biological, p38 Mitogen-Activated Protein Kinases, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pharmacology (medical), Lung cancer, Adverse effect, education, Protein Kinase Inhibitors, Aged, Pharmacology, education.field_of_study, business.industry, Imidazoles, Cancer, Common Terminology Criteria for Adverse Events, Middle Aged, medicine.disease, Treatment Outcome, 030104 developmental biology, Response Evaluation Criteria in Solid Tumors, Pyrazines, 030220 oncology & carcinogenesis, Checkpoint Kinase 1, Pyrazoles, Ralimetinib, Female, business, Febrile neutropenia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e75a04ddc23ef75c870beb94be16d9dTest
https://doi.org/10.1007/s10637-019-00873-6Test -
3
المؤلفون: Ruth Plummer, Rachel E. Sanborn, Fiona C Thistlethwaite, Omid Hamid, Daniel C. Cho, Lawrence Lu, Valentina Boni, Johanna C. Bendell, Mark Stroh, Elisabeth G.E. de Vries, Karen A. Autio, Patrick A. Ott, Javier Garcia-Corbacho
المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS)
المصدر: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for immunotherapy of cancer, 9(7):002446. BMCمصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Prodrugs, Immune Checkpoint Inhibitors, RC254-282, Clinical/Translational Cancer Immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Antibodies, Monoclonal, Middle Aged, Oncology, Tolerability, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Toxicity, Molecular Medicine, Female, immunotherapy, medicine.drug, Adult, CTLA-4 antigen, medicine.medical_specialty, Combination therapy, Immunology, therapies, Ipilimumab, investigational, 03 medical and health sciences, Internal medicine, medicine, Humans, Testicular cancer, Pneumonitis, Aged, Pharmacology, Dose-Response Relationship, Drug, business.industry, medicine.disease, 030104 developmental biology, NIVOLUMAB PLUS IPILIMUMAB, PD-L1 inhibitor, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f59b5f6c6c998d04c0063e8f4efa570Test
https://pubmed.ncbi.nlm.nih.gov/34301808Test -
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المؤلفون: Anna M. Szpurka, Sandaruwan Geeganage, Johanna C. Bendell, Johan Wallin, Shadia I. Jalal, Sylvie Rottey, Karim A. Benhadji, Hans Prenen, Leena Gandhi, Thompson N. Doman, Violeta Regnier Galvao, Nuria Kotecki, Subha Suriyapperuma, Meng Xia, Abhijoy Saha, P. Vuagnat, Xiaojian Xu, Bert H. O'Neil
المصدر: Journal of immunotherapy (Hagerstown, Md. : 1997)
مصطلحات موضوعية: Adult, Male, Cancer Research, Lung Neoplasms, Immunology, Triple Negative Breast Neoplasms, Pharmacology, B7-H1 Antigen, Young Adult, Breast cancer, Pharmacokinetics, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Immunology and Allergy, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Adverse effect, Kynurenine, Aged, Hepatitis, biology, business.industry, Middle Aged, medicine.disease, Tolerability, Pharmacodynamics, Toxicity, biology.protein, Female, Human medicine, Antibody, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baec1e12f207c37e1d3693c803fac61Test
https://hdl.handle.net/10067/1804940151162165141Test -
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المؤلفون: Herbert Hurwitz, Vaibhav Sahai, Chris Verslype, Jason Clark, Johanna C. Bendell, Ashwin Reddy Sama, Eric Van Cutsem, Manuel Hidalgo, Edward W Greeno, Eileen M. O'Reilly, Chung Pin Li, Kenneth H. Yu, Christopher James Walker, Fitzroy Dawkins, Teresa Macarulla, Marcelo Garrido Salvo
المصدر: Investigational New Drugs. 36:683-695
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Ruxolitinib, Placebo, Disease-Free Survival, Article, Capecitabine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Pancreatic cancer, Antineoplastic Combined Chemotherapy Protocols, Nitriles, medicine, Clinical endpoint, Humans, Pharmacology (medical), Aged, Aged, 80 and over, Pharmacology, business.industry, Hazard ratio, Janus Kinase 1, Janus Kinase 2, Middle Aged, medicine.disease, Chemotherapy regimen, Pancreatic Neoplasms, Clinical trial, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Disease Progression, Pyrazoles, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4efb9dd95fab56ab09c97a08030248fTest
https://doi.org/10.1007/s10637-018-0580-2Test -
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المؤلفون: Erika Hamilton, Hani Gabra, Kathleen M. Moore, Jennifer R. Diamond, Mark Poole, D. Ross Camidge, Martin D. Forster, Michael S. Gordon, David M. Waterhouse, Barbara A. Goff, Carolyn D. Britten, Johanna C. Bendell
المصدر: Invest New Drugs
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, Mitochondrial inhibitor, Cell, Uterine Cervical Neoplasms, Neutropenia, Article, Drug Administration Schedule, 03 medical and health sciences, 0302 clinical medicine, Stable Disease, Pharmacokinetics, Ovarian cancer, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, ME-344, Pharmacology (medical), Oncology & Carcinogenesis, Aged, Ovarian Neoplasms, Pharmacology, Lung, Dose-Response Relationship, Drug, Small cell lung cancer, business.industry, Middle Aged, medicine.disease, Isoflavones, Mitochondria, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, Female, 1115 Pharmacology And Pharmaceutical Sciences, Topotecan, Neoplasm Recurrence, Local, Topoisomerase I Inhibitors, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dee4e7e022a14638395d5059e46ddfTest
https://doi.org/10.1007/s10637-017-0444-1Test -
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المؤلفون: Jean-Luc Van Laethem, Frederico Longo Muñoz, Thea Kalebic, Khaldoun Almhanna, Maria Alsina, Carolina Muriel Lopez, Antonio Cubillo Gracian, Hadi Danaee, Irfan Firdaus, Zhan Ye, Adedigbo Fasanmade, Johanna C. Bendell, Wells A. Messersmith, David Wright, Richard A. Hubner, Maria Luisa Limon Miron
المصدر: Investigational New Drugs. 35:235-241
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Immunoconjugates, Esophageal Neoplasms, Receptors, Enterotoxin, Phases of clinical research, Antineoplastic Agents, Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Neutropenia, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Stomach Neoplasms, Internal medicine, medicine, Humans, Pharmacology (medical), Gastrointestinal cancer, Aged, Aged, 80 and over, Pharmacology, business.industry, Guanylate cyclase 2C, Middle Aged, medicine.disease, Interim analysis, Tumor Burden, Surgery, Treatment Outcome, 030104 developmental biology, Oncology, Monomethyl auristatin E, chemistry, 030220 oncology & carcinogenesis, Female, Esophagogastric Junction, Neoplasm Recurrence, Local, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e4a2ebe65fb4b73b1a74204841d4eaTest
https://doi.org/10.1007/s10637-017-0439-yTest -
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المؤلفون: Sunil Sharma, Emin Avsar, Kati Maharry, Jan H.M. Schellens, Anna Spreafico, Rona Yaeger, Martin Schuler, Jason E. Faris, Takayuki Yoshino, Arkendu Chatterjee, Savina Jaeger, Ferry A.L.M. Eskens, Johanna C. Bendell, Tim Demuth, Josep Tabernero, Martijn P. Lolkema, Zev A. Wainberg, Yasuhide Yamada, Jean Pierre Delord, Robin M.J.M. van Geel, Eugene Tan, Elena Elez, Heinz-Josef Lenz
المساهمون: MUMC+: DA KFT Medische Staf (9), RS: FHML non-thematic output, Medical Oncology
المصدر: Cancer Discovery, 7(6), 610-619. American Association for Cancer Research Inc.
Cancer discovery, vol 7, iss 6
Cancer Discovery, 7(6), 610. American Association for Cancer Research Inc.مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Colorectal cancer, Medizin, Cetuximab, Raf Kinase Inhibitor, Pharmacology, 0302 clinical medicine, Encorafenib, Antineoplastic Combined Chemotherapy Protocols, 80 and over, Phosphoinositide-3 Kinase Inhibitors, Cancer, Aged, 80 and over, Sulfonamides, COLON-CANCER, Middle Aged, Clinical Trial, Colo-Rectal Cancer, 3. Good health, Multicenter Study, Tolerability, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Maximum Tolerated Dose, EGFR, Oncology and Carcinogenesis, BIOMARKERS, INHIBITION, Antineoplastic Agents, Disease-Free Survival, Clinical Trial, Phase I, 03 medical and health sciences, Phase I, SDG 3 - Good Health and Well-being, Clinical Research, Internal medicine, MAPK PATHWAY, medicine, Journal Article, KRAS, Humans, WILD-TYPE, neoplasms, Protein Kinase Inhibitors, Aged, business.industry, Evaluation of treatments and therapeutic interventions, RAF, medicine.disease, digestive system diseases, FLUOROURACIL, Clinical trial, Thiazoles, 030104 developmental biology, Concomitant, Mutation, GENE COPY NUMBER, Carbamates, Phosphatidylinositol 3-Kinase, Digestive Diseases, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a74efca771fba8318569827a37a712fTest
https://hdl.handle.net/1765/108310Test -
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المؤلفون: John Nemunaitis, Luis Paz-Ares, Amit Mahipal, Shaoyi Li, Pamela N. Munster, Tim Meyer, Hans A. de Haan, Kristen Hege, Monica M. Mita, Johanna C. Bendell, Edward M. Wolin, Ellen Filvaroff, Alain C. Mita
المساهمون: Deming, Dustin A
المصدر: PLoS ONE
PloS one, vol 14, iss 9
Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS ONE, Vol 14, Iss 9, p e0221994 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Kinase Inhibitors, Cancer Treatment, Phases of clinical research, Administration, Oral, Neuroendocrine tumors, Toxicology, Pathology and Laboratory Medicine, Gastroenterology, Biochemistry, Cohort Studies, 0302 clinical medicine, Drug Metabolism, Medicine and Health Sciences, Enzyme Inhibitors, Stomatitis, Cancer, Gastrointestinal Neoplasms, Multidisciplinary, Middle Aged, Body Fluids, Neuroendocrine Tumors, Blood, Tolerability, Oncology, Research Design, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Pyrazines, Administration, Toxicity, Medicine, Female, Anatomy, Research Article, Oral, Adult, Diarrhea, medicine.medical_specialty, Maximum Tolerated Dose, General Science & Technology, Clinical Research Design, Science, Carcinoid Tumor, Mechanistic Target of Rapamycin Complex 2, Gastroenterology and Hepatology, Mechanistic Target of Rapamycin Complex 1, Research and Analysis Methods, 03 medical and health sciences, Rare Diseases, Signs and Symptoms, Pharmacokinetics, Refractory, Clinical Research, Diagnostic Medicine, Internal medicine, medicine, Humans, Adverse effect, Aged, Pharmacology, business.industry, Evaluation of treatments and therapeutic interventions, Biology and Life Sciences, medicine.disease, 030104 developmental biology, Enzymology, Adverse Events, Digestive Diseases, business, Biomarkers
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c063f01d24cfba07ad4d4f15e01acfTest
https://pubmed.ncbi.nlm.nih.gov/31527867Test -
10
المؤلفون: Lee-Anne Stayner, Yuehui Wu, G. Del Conte, Johanna C. Bendell, Rajeshwar Singh, Philippe L. Bedard, Albiruni Ryan Abdul Razak, Cornfeld Mark J, R. Greenwood, Leanne Cartee, Cristiana Sessa, Angelica Fasolo, Juneko E. Grilley-Olson, H. A. Burris, Carrie B. Lee, J. R. Infante
المصدر: Invest New Drugs
مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, MAP Kinase Kinase 1, Phases of clinical research, Pharmacology, 0302 clinical medicine, Neoplasms, Tissue Distribution, Pharmacology (medical), Phosphoinositide-3 Kinase Inhibitors, Trametinib, Sulfonamides, TOR Serine-Threonine Kinases, MEK inhibitor, Middle Aged, Prognosis, Rash, Pyridazines, Survival Rate, Tolerability, 030220 oncology & carcinogenesis, Quinolines, Drug Therapy, Combination, Female, medicine.symptom, Adult, medicine.medical_specialty, Maximum Tolerated Dose, Pyridones, Pyrimidinones, Article, Young Adult, 03 medical and health sciences, Pharmacokinetics, Internal medicine, Biomarkers, Tumor, medicine, Humans, Dosing, Adverse effect, Protein Kinase Inhibitors, Aged, Neoplasm Staging, business.industry, 030104 developmental biology, business, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c534d7a980196bd8d32b6653fb8a0fc2Test
https://doi.org/10.1007/s10637-016-0377-0Test