المؤلفون: Juan A Gomez, Trinayan Kashyap, Yun Dai, Alexis Bauer, Yosef Landesman, Steven Grant, Jana L. Dawson, Daniel M. Sullivan, Kenneth H. Shain, Joel G. Turner, Mark B. Meads

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Transcription, Genetic, Receptors, Cytoplasmic and Nuclear, Apoptosis, Mice, SCID, Pharmacology, acquired drug resistance, Bortezomib, chemistry.chemical_compound, 0302 clinical medicine, NF-KappaB Inhibitor alpha, immune system diseases, Mice, Inbred NOD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Multiple myeloma, Hematology, carfilzomib, Protein Stability, NF-kappa B, 3. Good health, multiple myeloma, Gene Expression Regulation, Neoplastic, Hydrazines, Oncology, 030220 oncology & carcinogenesis, XPO1, Female, RNA Interference, Oligopeptides, medicine.drug, Research Paper, medicine.medical_specialty, Proteasome Endopeptidase Complex, Combination therapy, Active Transport, Cell Nucleus, Karyopherins, Transfection, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Cell Nucleus, Dose-Response Relationship, Drug, business.industry, Cancer, Triazoles, medicine.disease, Carfilzomib, Xenograft Model Antitumor Assays, IκBα, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Proteolysis, Cancer research, Proteasome inhibitor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98489c6e2519a954c0d72b3e5c986af8Test
http://europepmc.org/articles/PMC5340237Test

المؤلفون: Caryn Weir-Wiggins, Wen Wan, John D. Roberts, Maciej Kmieciak, Viswanathan Ramakrishnan, Loveleen Kang, Rachid Baz, Cody J. Peer, Steven Grant, G. David Roodman, E. Brent Perkins, L. Austin Doyle, Prithviraj Bose, Martha D. Wellons, Robert K. Stuart, A. Dimitrios Colevas, Daniel C. Sullivan, Heidi Sankala, Beata Holkova, Ellen Shrader, William D. Figg, Kevin T. Hogan, Connie Honeycutt, Domenico Coppola, Mary Beth Tombes, Jana L. Dawson

المصدر: Clinical Cancer Research. 20:5652-5662

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Neutropenia, Pharmacology, Article, Drug Administration Schedule, Bortezomib, chemistry.chemical_compound, Piperidines, Recurrence, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Multiple myeloma, Aged, Flavonoids, B-Lymphocytes, Leukopenia, business.industry, Waldenstrom macroglobulinemia, Middle Aged, Alvocidib, medicine.disease, Boronic Acids, Combined Modality Therapy, Lymphoproliferative Disorders, Regimen, Treatment Outcome, chemistry, Pyrazines, Retreatment, Female, Mantle cell lymphoma, Drug Monitoring, medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390b15badeec929de98b3fd33b94b857Test
https://doi.org/10.1158/1078-0432.ccr-14-0805Test

المؤلفون: Prithviraj Bose, Thomas C. Shea, Amanda Garnett Singh, Heidi Sankala, Steven Grant, Victor Yazbeck, John D. Roberts, Beata Holkova, Kevin T. Hogan, Shuo Ma, Caryn Weir-Wiggins, Amy S. Kimball, Ellen Shrader, Sarah Conine, Wen Wan, Maciej Kmieciak, Mary Beth Tombes

المصدر: Leukemialymphoma. 58(6)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, medicine.medical_specialty, Pathology, Maximum Tolerated Dose, Chronic lymphocytic leukemia, Article, Romidepsin, Bortezomib, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, hemic and lymphatic diseases, Depsipeptides, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, B-cell lymphoma, neoplasms, business.industry, Cutaneous T-cell lymphoma, Lymphoma, T-Cell, Peripheral, Hematology, medicine.disease, Combined Modality Therapy, Leukemia, Lymphocytic, Chronic, B-Cell, Peripheral T-cell lymphoma, Lymphoma, Lymphoma, T-Cell, Cutaneous, 030104 developmental biology, Treatment Outcome, 030220 oncology & carcinogenesis, Female, business, Progressive disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb7ccddef0e8ce3595d365d5029c50bTest
https://pubmed.ncbi.nlm.nih.gov/28103725Test

المؤلفون: Hossein A. Hamed, Paul Dent, Steven Grant, Seyedmehrad Tavallai, Andrew Poklepovic

المصدر: Cancer Biology & Therapy. 15:578-585

مصطلحات موضوعية: Cancer Research, Indazoles, Mice, Nude, Antineoplastic Agents, Biology, Pharmacology, Autophagy-Related Protein 5, Pazopanib, Cell Line, Tumor, Autophagy, medicine, Animals, FADD, Protein kinase B, Vorinostat, PI3K/AKT/mTOR pathway, Sulfonamides, Gene knockdown, Valproic Acid, Membrane Proteins, Drug Synergism, Sarcoma, Receptors, Death Domain, medicine.disease, Histone Deacetylase Inhibitors, Pyrimidines, Oncology, Gene Knockdown Techniques, Cancer research, biology.protein, Molecular Medicine, Beclin-1, Female, Histone deacetylase, Apoptosis Regulatory Proteins, Microtubule-Associated Proteins, Research Paper, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c4c52696d45c8d532ac245ed88ab37Test
https://doi.org/10.4161/cbt.28163Test

المؤلفون: David S. Morgan, Ellen Shrader, Lubomir Sokol, Victor Yazbeck, Daniel C. Sullivan, Prithviraj Bose, Samir Parekh, Danielle Shafer, Rachid Baz, Maciej Kmieciak, Ashraf Badros, Kristy L. Richards, Richard R. Reich, Jia Ruan, John D. Roberts, Beata Holkova, Hui-Yi Lin, Christopher R. Flowers, Domenico Coppola, Mary Beth Tombes, Xiuhua Zhao, Roger Strair, Amy S. Kimball, Thomas B. Shea, Heidi Sankala, Steven Grant, Edward B. Perkins

المصدر: Clinical Lymphoma Myeloma and Leukemia. 18:569-575.e1

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Lymphoma, Mantle-Cell, Bortezomib, 03 medical and health sciences, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Prospective Studies, neoplasms, Vorinostat, Multiple myeloma, Aged, Aged, 80 and over, Salvage Therapy, business.industry, Hematology, Middle Aged, Prognosis, medicine.disease, Survival Rate, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cohort, Proteasome inhibitor, Female, Mantle cell lymphoma, Lymphoma, Large B-Cell, Diffuse, Neoplasm Recurrence, Local, business, Diffuse large B-cell lymphoma, Progressive disease, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d3bd2e89e8052faa3951c144dde225Test
https://doi.org/10.1016/j.clml.2018.05.023Test

المؤلفون: Laurence Booth, Paul Dent, Hossein A. Hamed, Steven Grant, Jahangir Syed, Gangadharan B. Sajithlal, Nichola Cruickshanks, Seyedmehrad Tavallai, Andrew Poklepovic

المصدر: Molecular Pharmacology. 84:562-571

مصطلحات موضوعية: Niacinamide, Sorafenib, Thymoma, Pyridines, Cell Communication, Gonanes, Pharmacology, Biology, Proto-Oncogene Mas, Mice, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, GSK-3, Cell Line, Tumor, Regorafenib, medicine, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Cell Death, Kinase, Phenylurea Compounds, Drug Synergism, Hep G2 Cells, Thymus Neoplasms, Articles, Perifosine, Xenograft Model Antitumor Assays, Cell killing, chemistry, Molecular Medicine, Female, Proto-Oncogene Proteins c-akt, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08501ce209ca1e89f042150f1b06b113Test
https://doi.org/10.1124/mol.113.088005Test

المؤلفون: Hossein A. Hamed, Laurence Booth, Yong Tang, Steven Grant, Paul Dent, Nichola Cruickshanks

المصدر: Molecular Pharmacology. 82:1217-1229

مصطلحات موضوعية: Programmed cell death, Indoles, Mice, Nude, Breast Neoplasms, Biology, Lapatinib, p38 Mitogen-Activated Protein Kinases, Mice, eIF-2 Kinase, chemistry.chemical_compound, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, Autophagy, medicine, Animals, Humans, Mitogen-Activated Protein Kinase 9, PTEN, HSP70 Heat-Shock Proteins, Mitogen-Activated Protein Kinase 8, Pyrroles, Protein kinase A, Pharmacology, EIF-2 kinase, Membrane Proteins, Articles, Endoplasmic Reticulum Stress, Mitochondria, Cell killing, chemistry, Quinazolines, Cancer research, biology.protein, Molecular Medicine, Female, Reactive Oxygen Species, Obatoclax, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8a2111c680b524f40b85075bf48d04Test
https://doi.org/10.1124/mol.112.081539Test

المؤلفون: Steven Grant, Paul Dent, Jeremy C. Allegood, Andrew Poklepovic, Sarah Spiegel, Besim Ogretmen, Nichola Cruickshanks, Margaret A. Park, Hossein A. Hamed, M. Danielle Bareford

المصدر: Cancer Biology & Therapy. 13:793-803

مصطلحات موضوعية: Niacinamide, MAPK/ERK pathway, Sorafenib, Cancer Research, medicine.medical_specialty, Ceramide, Guanine, MAP Kinase Signaling System, Pyridines, Antineoplastic Agents, Breast Neoplasms, Endosomes, Pemetrexed, Biology, Receptor, Platelet-Derived Growth Factor beta, chemistry.chemical_compound, Glutamates, Cell Line, Tumor, Internal medicine, Autophagy, medicine, Humans, Protein Phosphatase 2, Extracellular Signal-Regulated MAP Kinases, Ceramide synthase, Pharmacology, Phenylurea Compounds, Benzenesulfonates, Drug Synergism, Protein phosphatase 2, Enzyme Activation, src-Family Kinases, Endocrinology, Oncology, chemistry, Gene Knockdown Techniques, Cancer cell, Cancer research, Molecular Medicine, Female, RNA Interference, Research Paper, Proto-oncogene tyrosine-protein kinase Src, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d42773d08083a74b0e4f8a1a6753dcTest
https://doi.org/10.4161/cbt.20562Test

المؤلفون: Mandy Mayo Aust, Elisa Attkisson, Mohamed Rahmani, Andrea Ferreira-Gonzalez, Steven Grant, David C. Williams

المصدر: Blood. 119:6089-6098

مصطلحات موضوعية: Niacinamide, Sorafenib, Indoles, Pyridines, Immunology, Mice, Nude, Apoptosis, HL-60 Cells, Biology, Biochemistry, Mice, chemistry.chemical_compound, Proto-Oncogene Proteins, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Pyrroles, Clonogenic assay, neoplasms, Cells, Cultured, Gene knockdown, Myeloid Neoplasia, Bcl-2-Like Protein 11, Phenylurea Compounds, Benzenesulfonates, Autophagy, Membrane Proteins, Myeloid leukemia, Drug Synergism, U937 Cells, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Up-Regulation, Leukemia, Proto-Oncogene Proteins c-bcl-2, chemistry, Leukemia, Myeloid, Cancer research, Female, Apoptosis Regulatory Proteins, Obatoclax, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eeb95b4fed43aa25d02ce71b086dc3Test
https://doi.org/10.1182/blood-2011-09-378141Test

المؤلفون: Ellen Shrader, Changyong Feng, Prithviraj Bose, Richard I. Fisher, Paul M. Barr, Jonathan W. Friedberg, Heidi Sankala, Kevin T. Hogan, Maciej Kmieciak, Victor Yazbeck, Emily Pierce, Derick R. Peterson, Caryn Weir-Wiggins, April D. Rollins, Megan M. Herr, Beata Holkova, Steven Grant, Erin Cebula, Mary Beth Tombes, Wen Wan

المصدر: Leukemialymphoma. 57(3)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Lymphoma, B-Cell, Phases of clinical research, Pharmacology, Hydroxamic Acids, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Refractory, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Vorinostat, Pneumonitis, Aged, business.industry, Hematology, Middle Aged, medicine.disease, Carfilzomib, Combined Modality Therapy, Lymphoma, 030104 developmental biology, Treatment Outcome, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Retreatment, Cytokines, Female, Drug Monitoring, Neoplasm Recurrence, Local, business, Hyponatremia, Oligopeptides, Febrile neutropenia, Biomarkers, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a568fafae0a9a514b7a1116e37e844Test
https://pubmed.ncbi.nlm.nih.gov/26284612Test