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المؤلفون: Hans-Peter Hammes, Elena Heidenreich, Peter P. Nawroth, Martina U. Muckenthaler, Sandro Altamura, Thomas Fleming, Andrea Schlotterer, Katja Müdder, Ruiyue Qiu
المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, DR, diabetic retinopathy, Hepcidin, medicine.disease_cause, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, MetS, Metabolic Syndrome, Internal medicine, biology, Fpn, Ferroportin, Fatty liver, Liver, DIOS, dysmetabolic iron overload syndrome, CRP, C-reactive protein, Receptors, Leptin, HH, hereditary hemochromatosis, Original Article, IRP, Iron Regulatory Protein, medicine.medical_specialty, Iron Overload, Iron, 030209 endocrinology & metabolism, Mice, Transgenic, IR, Insulin Resistance, SEM, standard error of the mean, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, NASH, Non Alcoholic Steatohepatitis, NAFLD, medicine, Animals, Humans, Molecular Biology, business.industry, NTBI, Non Transferrin Bound Iron, Cell Biology, medicine.disease, RC31-1245, IRS1, Db/db Mouse, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, NAFLD, Non Alcoholic Fatty Liver Disease, Lipid Peroxidation, Steatosis, Metabolic syndrome, business, Oxidative stress, IRE, Iron Responsive Element, T2DM, Type 2 Diabetes Mellitus
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ad7abfa625d87337f2502f8e59462Test
http://www.sciencedirect.com/science/article/pii/S2212877821000806Test -
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المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze
المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase
وصف الملف: application/pdf
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المؤلفون: Mayumi Nagashimada, Eric Mayoux, Naoto Nagata, Guanliang Chen, Liang Xu, Shuichi Kaneko, Yinhua Ni, Fen Zhuge, Tsuguhito Ota
المصدر: EBioMedicine
EBioMedicine, Vol 20, Iss C, Pp 137-149 (2017)مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, FGF21, Macrophage, lcsh:Medicine, AST, aspartate aminotransferase, White adipose tissue, 030204 cardiovascular system & hematology, ATMs, adipose tissue macrophages, Brown adipose tissue, EGP, endogenous glucose production, Mice, 0302 clinical medicine, Glucosides, FACS, fluorescence-activated cell sorting, TBARS, thiobarbituric acid reactive substances, Empa, empagliflozin, RER, respiratory exchange ratio, Adiposity, lcsh:R5-920, Glucose tolerance test, medicine.diagnostic_test, NEFA, non-esterified fatty acid, Fatty Acids, CT, computed tomographic, WAT, white adipose tissue, DIO, high-fat-diet-induced obese, General Medicine, TG, triglycerides, Adipose Tissue, H&E, haematoxylin and eosin, GTT, glucose tolerance test, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Adipose tissue macrophages, Biology, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, VCO2, carbon dioxide production, FGF21, fibroblast growth factor, Internal medicine, UCP1, uncoupling protein 1, medicine, Empagliflozin, Animals, Hypoglycemic Agents, Obesity, Benzhydryl Compounds, Muscle, Skeletal, Sodium-Glucose Transporter 2 Inhibitors, ITT, insulin tolerance test, VO2, oxygen consumption, Inflammation, Macrophages, lcsh:R, SGLT, sodium/glucose cotransporter, Sodium glucose cotransporter-2 inhibitor, Body Weight, Insulin tolerance test, ALT, Alanine aminotransferase, Energy metabolism, UGE, urinary glucose excretion, Macrophage Activation, medicine.disease, BAT, brown adipose tissue, TC, total cholesterol, Fatty Liver, AMPK, AMP-activated protein kinase, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, LMs, liver macrophages, Diet-induced obese, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85fd9e3671e9effaeef0acf4b89dd1Test
https://doi.org/10.1016/j.ebiom.2017.05.028Test -
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المؤلفون: Lionel Carneiro, François R Jornayvaz, Christine Sempoux, Corinne Leloup, Jean-Christophe Stehle, Mohamed Asrih, Luc Pellerin, Cendrine Repond
المساهمون: Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Service d'Endocrinologie, Diabétologie et Métabolisme, Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Department of Physiology, Université de Lausanne (UNIL), Université Catholique de Louvain (UCL), Département de Physiologie, Pellerin, Luc, Centre National de la Recherche Scientifique (CNRS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), Université Catholique de Louvain = Catholic University of Louvain (UCL), the 'Societe francophone du Diabete', the program IdEx Bordeaux ANR-10-IDEX-03-02, the Leenaards Foundation and the Raymond Berger Foundation, Lausanne., Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), Centre Hospitalier Universitaire Vaudois [Lausanne] ( CHUV ), University of Lausanne, Université Catholique de Louvain ( UCL ), Université de Lausanne ( UNIL )
المصدر: Molecular metabolism, vol. 6, no. 12, pp. 1625-1633
Molecular Metabolism, Vol. 6, No 12 (2017) pp. 1625-1633
Molecular Metabolism, Vol 6, Iss 12, Pp 1625-1633 (2017)
Molecular metabolism
Molecular metabolism, Elsevier, 2017, 6 (12), pp.1625-1633. ⟨10.1016/j.molmet.2017.10.005⟩
Molecular Metabolism 12 (6), 1625-1633. (2017)
Molecular metabolism, Elsevier, 2017, 6 (12), pp.1625-1633. 〈10.1016/j.molmet.2017.10.005〉
Molecular Metabolismمصطلحات موضوعية: Male, 0301 basic medicine, AMPK, a.u.c, Area Under the Curve, Hepatic steatosis, Haploinsufficiency, FA, Fatty Acids, Mice, 0302 clinical medicine, AMP-Activated Protein Kinase Kinases, NAFLD, Non-Alcoholic Fatty Liver Disease, S6K, Ribosomal protein S6 kinase, ddc:616, Symporters, Diabetes, Fatty liver, foie, Rd, Glucose disappearance rate, HFD, High Fat Diet, obésité, Liver, Endocrinologie et métabolisme, Sterol Regulatory Element Binding Protein 1, LDHB, Lactate DeHydrogenase isoform B, diabète, Monocarboxylic Acid Transporters, PC, Pyruvate Carboxylase, medicine.medical_specialty, lcsh:Internal medicine, NASH, Non-Alcoholic SteatoHepatitis, kinase, SREBP1, Sterol Regulatory Element Binding Protein 1, 030209 endocrinology & metabolism, Biology, Brief Communication, maladie, 03 medical and health sciences, Animals, Fatty Liver/genetics, Fatty Liver/metabolism, Lactic Acid/metabolism, Lipid Metabolism, Liver/metabolism, Monocarboxylic Acid Transporters/genetics, Monocarboxylic Acid Transporters/metabolism, Protein Kinases/metabolism, Sterol Regulatory Element Binding Protein 1/metabolism, Symporters/genetics, Symporters/metabolism, Lactate, NAFLD, Obesity, stéatose hépatique, Downregulation and upregulation, SD, Standard Diet, [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology, Internal medicine, medicine, TAG, TriAcylGlycerides, Lactic Acid, lcsh:RC31-1245, résistance à l'insuline, Molecular Biology, HGP, Hepatic Glucose Production, liver, nafld, diabetes, lactate, insulin-resistance, nonalcoholic steatohepatitis, disease, obesity, ER Stress, Endoplasmic Reticulum stress, Endocrinology and metabolism, GIR, Glucose Infusion Rate, Lipid metabolism, Cell Biology, Metabolism, medicine.disease, Sterol regulatory element-binding protein, Fatty Liver, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, MCT1, Monocarboxylate Transporter isoform 1, mTOR, mammalian Target Of Rapamycin, Steatosis, ACC, Acetyl-CoA Carboxylase, Protein Kinases, Drug metabolism, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, ROS, Reactive Oxygen Species, LDHA, Lactate DeHydrogenase isoform A
وصف الملف: application/pdf
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https://serval.unil.ch/notice/serval:BIB_1E26E53BF1FETest -
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المؤلفون: Maelle Morgan, Barbara Sigalla, J Soeda, Chad McKee, Tania Roskams, Esra Asilmaz, Jude A. Oben, Nicoletta Sinelli
المصدر: Biochemical and Biophysical Research Communications
مصطلحات موضوعية: Male, Cirrhosis, Apoptosis, HPC, hepatic progenitor cell, Biochemistry, Choline, Mice, chemistry.chemical_compound, 0302 clinical medicine, Ethionine, Liver injury, 0303 health sciences, Stem Cells, Alanine Transaminase, Fas receptor, Propranolol, 3. Good health, medicine.anatomical_structure, Liver, 030220 oncology & carcinogenesis, Hepatocyte, PRZ, prazosin, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, Fas Ligand Protein, NASH, non-alcoholic steatohepatitis, Adrenergic beta-Antagonists, Biophysics, Biology, Article, 03 medical and health sciences, Internal medicine, Receptors, Adrenergic, beta, medicine, Animals, Molecular Biology, 030304 developmental biology, L-Lactate Dehydrogenase, Tumor Necrosis Factor-alpha, PRL, propranolol, OC, oval cell, Antagonist, Cell Biology, medicine.disease, Culture Media, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, chemistry, Sympathetic nervous system, Hepatocytes, Hepatic stellate cell, Steatohepatitis, Non-alcoholic fatty liver disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f003a82453155f5ae4f332cad7b55123Test
https://doi.org/10.1016/j.bbrc.2013.07.005Test -
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المؤلفون: Shannon M. Bailey, Heather B. Eccleston, David W. Kraus, Victor M. Darley-Usmar, Sudheer K. Mantena, Jeannette E. Doeller, Kelly K. Andringa, Adrienne L. King, Denty Paul Vaughn, Gary A. Abrams
المصدر: Biochemical Journal
مصطلحات موضوعية: Male, Bioenergetics, Nitric Oxide Synthase Type II, Mitochondria, Liver, Mitochondrion, medicine.disease_cause, Biochemistry, JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol carbo-cyanine iodide, chemistry.chemical_compound, Mice, 0302 clinical medicine, HFD, high fat diet, cytochrome c oxidase, 3-NT, 3-nitrotyrosine, Hypoxia, Membrane Potential, Mitochondrial, 0303 health sciences, Fatty liver, CYP2E1, cytochrome P450 2E1, Cytochrome P-450 CYP2E1, 3. Good health, mitochondria, FCCP, carbonyl cyanide p-trifluoromethoxyphenylhydrazone, 030220 oncology & carcinogenesis, iNOS, inducible nitric oxide synthase, non-alcoholic steatohepatitis, RCR, respiratory control ratio, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Cellular respiration, NASH, non-alcoholic steatohepatitis, Cell Respiration, Biology, liver, Nitric Oxide, Nitric oxide, PAPA NONOate, 1-propanamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazino), DAB, diaminobenzidine, RNS, reactive nitrogen species, Mitochondrial Proteins, 03 medical and health sciences, ROS, reactive oxygen species, Internal medicine, medicine, Animals, Molecular Biology, Reactive nitrogen species, 030304 developmental biology, nutritional and metabolic diseases, Cell Biology, medicine.disease, Dietary Fats, Fatty Liver, Mice, Inbred C57BL, Oxidative Stress, Endocrinology, chemistry, Tyrosine, Steatohepatitis, Oxidative stress, DAPI, 4′,6-diamidino-2-phenylindole
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8ad50b2a6a6f4a72113fc86354941bTest
http://europepmc.org/articles/PMC2637578Test -
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المؤلفون: Wayne Bond Lau, Yan Lee, Huishou Zhao, Kun Lian, Wenjun Yan, Xiyao Chen, Shihao Zhao, Wei Wang, Jinglong Zhang, Ling Zhang, Fuyang Zhang, Feng Yan, Cheng Peng, Ling Tao, Chao Gao, Yunlong Xia, Xin-Liang Ma
المصدر: EBioMedicine, Vol 13, Iss C, Pp 157-167 (2016)
EBioMedicineمصطلحات موضوعية: Male, AMP-Activated Protein Kinases, TNF-α, tumor necrosis factor-α, Mice, HFD, high fat diet, HSL, hormone sensitive lipase, AMP-activated protein kinase, AST, aspartate transaminase, BCKD, branched-chain α-ketoacid dehydrogenase, IL-6, interleukin-6, TUNEL, terminal deoxynucleotidyl transferased UTP nick end labeling, Liver injury, TG, triglyceride, TOR Serine-Threonine Kinases, Branched chain amino acids, IRS1, insulin receptor substrate-1, General Medicine, DGAT1, diacylglycerol acyltransferase-1, lcsh:Medicine (General), Lipotoxicity, medicine.medical_specialty, IL-1β, interleukin-1β, NASH, non-alcoholic steatohepatitis, Lipolysis, mTOR, mammalian target of rapamycin, SEM, standard error of the mean, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, IU, international unit, TGF-β, transforming growth factor-β, GFP-LC3, green fluorescent protein-light chain-3, BCKA, branched chain α-ketoacids, MDA, malondialdehyde, lcsh:R, β-AR, β-adrenergic receptor, OA, oleic acid, medicine.disease, BCAA, branched chain amino acids, 030104 developmental biology, Endocrinology, chemistry, siRNA, small interfering RNA, PKA, protein kinase A, Amino Acids, Branched-Chain, Blood Glucose, 0301 basic medicine, FASN, fatty acid synthase, Mice, Obese, lcsh:Medicine, chemistry.chemical_compound, Liver Function Tests, DG, diacylglycerol, Adipocytes, FFA, free fatty acids, ANOVA, analysis of variance, BDK, branched-chain α-ketoacid dehydrogenase kinase, lcsh:R5-920, AMPK, adenosine monophosphate-activated protein kinase, Mammalian target of rapamycin, biology, ND, normal diet, Fatty liver, MCP-1, monocyte chemotactic protein-1, cAMP, cyclic adenosine monophosphate, HPLC, high performance liquid chromatography, Lipogenesis, GTT, glucose tolerance test, SREBP-1c, sterol regulatory element binding protein-1c, Research Paper, NAFLD, non-alcoholic fatty liver disease, Normal diet, ELOVL6, elongation of very long chain fatty acids protein-6, HOMA-IR, homeostasis model assessment of insulin resistance, PP2Cm, protein phosphatase-2Cm, Hyperlipidemias, Mice, Transgenic, ISO, isoprenaline, Diabetes Mellitus, Experimental, ROS, reactive oxygen species, HE, hematoxylin-eosin, ALT, alanine aminotransferase, SOD, superoxide dismutase, 3T3-L1 Cells, Internal medicine, Autophagy, medicine, Animals, ACC, acetyl-coA carboxylase, ITT, insulin tolerance test, ATGL, adipose triglyceride lipase, Triglyceride, Body Weight, SCD1, stearoyl-CoA desaturase-1, IP, intraperitoneal injection, Disease Models, Animal, Hepatocytes, biology.protein, BSA, bovine serum albumin, Non-alcoholic fatty liver disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ed5eb12a69790abfde563ef0de6601Test