المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

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المؤلفون: Maelle Morgan, Barbara Sigalla, J Soeda, Chad McKee, Tania Roskams, Esra Asilmaz, Jude A. Oben, Nicoletta Sinelli

المصدر: Biochemical and Biophysical Research Communications

مصطلحات موضوعية: Male, Cirrhosis, Apoptosis, HPC, hepatic progenitor cell, Biochemistry, Choline, Mice, chemistry.chemical_compound, 0302 clinical medicine, Ethionine, Liver injury, 0303 health sciences, Stem Cells, Alanine Transaminase, Fas receptor, Propranolol, 3. Good health, medicine.anatomical_structure, Liver, 030220 oncology & carcinogenesis, Hepatocyte, PRZ, prazosin, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, Fas Ligand Protein, NASH, non-alcoholic steatohepatitis, Adrenergic beta-Antagonists, Biophysics, Biology, Article, 03 medical and health sciences, Internal medicine, Receptors, Adrenergic, beta, medicine, Animals, Molecular Biology, 030304 developmental biology, L-Lactate Dehydrogenase, Tumor Necrosis Factor-alpha, PRL, propranolol, OC, oval cell, Antagonist, Cell Biology, medicine.disease, Culture Media, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, chemistry, Sympathetic nervous system, Hepatocytes, Hepatic stellate cell, Steatohepatitis, Non-alcoholic fatty liver disease

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https://doi.org/10.1016/j.bbrc.2013.07.005Test

المؤلفون: Wayne Bond Lau, Yan Lee, Huishou Zhao, Kun Lian, Wenjun Yan, Xiyao Chen, Shihao Zhao, Wei Wang, Jinglong Zhang, Ling Zhang, Fuyang Zhang, Feng Yan, Cheng Peng, Ling Tao, Chao Gao, Yunlong Xia, Xin-Liang Ma

المصدر: EBioMedicine, Vol 13, Iss C, Pp 157-167 (2016)
EBioMedicine

مصطلحات موضوعية: Male, AMP-Activated Protein Kinases, TNF-α, tumor necrosis factor-α, Mice, HFD, high fat diet, HSL, hormone sensitive lipase, AMP-activated protein kinase, AST, aspartate transaminase, BCKD, branched-chain α-ketoacid dehydrogenase, IL-6, interleukin-6, TUNEL, terminal deoxynucleotidyl transferased UTP nick end labeling, Liver injury, TG, triglyceride, TOR Serine-Threonine Kinases, Branched chain amino acids, IRS1, insulin receptor substrate-1, General Medicine, DGAT1, diacylglycerol acyltransferase-1, lcsh:Medicine (General), Lipotoxicity, medicine.medical_specialty, IL-1β, interleukin-1β, NASH, non-alcoholic steatohepatitis, Lipolysis, mTOR, mammalian target of rapamycin, SEM, standard error of the mean, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, IU, international unit, TGF-β, transforming growth factor-β, GFP-LC3, green fluorescent protein-light chain-3, BCKA, branched chain α-ketoacids, MDA, malondialdehyde, lcsh:R, β-AR, β-adrenergic receptor, OA, oleic acid, medicine.disease, BCAA, branched chain amino acids, 030104 developmental biology, Endocrinology, chemistry, siRNA, small interfering RNA, PKA, protein kinase A, Amino Acids, Branched-Chain, Blood Glucose, 0301 basic medicine, FASN, fatty acid synthase, Mice, Obese, lcsh:Medicine, chemistry.chemical_compound, Liver Function Tests, DG, diacylglycerol, Adipocytes, FFA, free fatty acids, ANOVA, analysis of variance, BDK, branched-chain α-ketoacid dehydrogenase kinase, lcsh:R5-920, AMPK, adenosine monophosphate-activated protein kinase, Mammalian target of rapamycin, biology, ND, normal diet, Fatty liver, MCP-1, monocyte chemotactic protein-1, cAMP, cyclic adenosine monophosphate, HPLC, high performance liquid chromatography, Lipogenesis, GTT, glucose tolerance test, SREBP-1c, sterol regulatory element binding protein-1c, Research Paper, NAFLD, non-alcoholic fatty liver disease, Normal diet, ELOVL6, elongation of very long chain fatty acids protein-6, HOMA-IR, homeostasis model assessment of insulin resistance, PP2Cm, protein phosphatase-2Cm, Hyperlipidemias, Mice, Transgenic, ISO, isoprenaline, Diabetes Mellitus, Experimental, ROS, reactive oxygen species, HE, hematoxylin-eosin, ALT, alanine aminotransferase, SOD, superoxide dismutase, 3T3-L1 Cells, Internal medicine, Autophagy, medicine, Animals, ACC, acetyl-coA carboxylase, ITT, insulin tolerance test, ATGL, adipose triglyceride lipase, Triglyceride, Body Weight, SCD1, stearoyl-CoA desaturase-1, IP, intraperitoneal injection, Disease Models, Animal, Hepatocytes, biology.protein, BSA, bovine serum albumin, Non-alcoholic fatty liver disease

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