نتائج البحث - "Floyd H. Chilton"

1

FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids

المؤلفون: Michael C. Seeds, Timothy D. Howard, Floyd H. Chilton, Rahul Dutta, Kirsten N. Lake, Rasika A. Mathias, Brian Hallmark, Lindsay M. Reynolds

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71a212e96bdbab27ade1702b4a544eeTest
http://link.springer.com/article/10.1038/s41598-020-71948-1Test

2

Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid– and ɣ-linolenic acid–containing botanical oils

المؤلفون: Tammy L Mustin, Laurel Johnstone, Michael C. Seeds, Floyd H. Chilton, Priscilla Ivester, Rasika A. Mathias, Maggie L Bohannon, Susan Sergeant, Brian Hallmark, Ingo Ruczinski

المصدر: Am J Clin Nutr

مصطلحات موضوعية: Fatty Acid Desaturases, Male, 0301 basic medicine, Medicine (miscellaneous), Cohort Studies, chemistry.chemical_compound, 8,11,14-Eicosatrienoic Acid, Delta-5 Fatty Acid Desaturase, Prospective Studies, chemistry.chemical_classification, education.field_of_study, Nutrition and Dietetics, biology, Middle Aged, Lipids, Original Research Communications, Fatty Acids, Unsaturated, lipids (amino acids, peptides, and proteins), Female, Borago, Polyunsaturated fatty acid, Adult, medicine.medical_specialty, Genotype, Linolenic acid, FADS1, Linoleic acid, Population, Polymorphism, Single Nucleotide, White People, Linoleic Acid, Young Adult, 03 medical and health sciences, Double-Blind Method, Internal medicine, medicine, Humans, Plant Oils, gamma-Linolenic Acid, gamma-Linolenic acid, education, Aged, 030109 nutrition & dietetics, business.industry, biology.organism_classification, Soybean Oil, 030104 developmental biology, Endocrinology, Fatty acid desaturase, chemistry, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a2a02ca9051d8805f91c6571d340c5Test
https://doi.org/10.1093/ajcn/nqaa023Test

3

Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations

المصدر: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Fatty Acid Desaturases, 0301 basic medicine, Heredity, QH301-705.5, Genetic genealogy, Medicine (miscellaneous), Single-nucleotide polymorphism, 030204 cardiovascular system & hematology, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Fatty Acids, Omega-3, Genetic variation, Genotype, medicine, Humans, SNP, Hispanic population, Longitudinal Studies, Biology (General), Genetic association study, Genetics, chemistry.chemical_classification, Genetic Variation, Hispanic or Latino, medicine.disease, United States, 030104 developmental biology, Risk factors, chemistry, Multigene Family, Indians, North American, Heritable quantitative trait, lipids (amino acids, peptides, and proteins), General Agricultural and Biological Sciences, Dyslipidemia, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606185dfba8a60327f61dd3c63569256Test
https://doi.org/10.1038/s42003-021-02431-4Test

4

Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

المؤلفون: Timothy D. Howard, Hannah C. Ainsworth, Floyd H. Chilton, Leslie R. Miller, Edward H. Kirby, Susan Sergeant, Charlotte Mae K. Waits, Tao Cui, Elaheh Rahbar, Carl D. Langefeld

المساهمون: Biomedical Engineering and Mechanics

المصدر: Clinical Epigenetics
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: 0301 basic medicine, Adult, CD4-Positive T-Lymphocytes, Fatty Acid Desaturases, Male, lcsh:QH426-470, lcsh:Medicine, Single-nucleotide polymorphism, Biology, White People, CD4+, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, Delta-5 Fatty Acid Desaturase, Genotype, Genetics, Leukocytes, Humans, Epigenetics, Saliva, Molecular Biology, Genetics (clinical), Alleles, Omega-6, FADS, DNA methylation, Research, Chromosomes, Human, Pair 11, lcsh:R, Promoter, Methylation, Middle Aged, Molecular biology, Healthy Volunteers, Whole blood, lcsh:Genetics, 030104 developmental biology, CpG site, chemistry, Organ Specificity, rs174537, Female, DNA, PUFA, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bca4b80e5ba7e400c2db6a1164285eTest
http://europepmc.org/articles/PMC5889567Test

5

Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression

المؤلفون: Lindsay M. Reynolds, Kanika Kanchan, Floyd H. Chilton, Rasika A. Mathias, Timothy D. Howard, Michael C. Seeds, Ingo Ruczinski

المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194610 (2018)

مصطلحات موضوعية: 0301 basic medicine, Fatty Acid Desaturases, Physiology, lcsh:Medicine, Gene Expression, Biochemistry, Delta-5 Fatty Acid Desaturase, Gene expression, Gene cluster, Medicine and Health Sciences, lcsh:Science, FADS1 Gene, Coronary Arteries, Genetics, Regulation of gene expression, Thyroid, Multidisciplinary, Genomics, Arteries, 3. Good health, Body Fluids, Blood, Organ Specificity, Multigene Family, Fatty Acids, Unsaturated, Anatomy, Research Article, Genotype, FADS1, FADS2, Quantitative Trait Loci, Single-nucleotide polymorphism, Endocrine System, Biology, Biosynthesis, Polymorphism, Single Nucleotide, 03 medical and health sciences, Genome-Wide Association Studies, Humans, Gene Regulation, Gene, Evolutionary Biology, 030109 nutrition & dietetics, Population Biology, lcsh:R, Biology and Life Sciences, Computational Biology, Human Genetics, Genome Analysis, 030104 developmental biology, Gene Expression Regulation, Genetic Polymorphism, Cardiovascular Anatomy, Blood Vessels, lcsh:Q, Population Genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738a79bc86127d92036e44ee93db49c9Test
http://europepmc.org/articles/PMC5874031Test

6

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

المؤلفون: Ingo Ruczinski, Tao Cui, Heinner Guio, Lisa R. Yanek, Rasika A. Mathias, Timothy D. O’Connor, Floyd H. Chilton, Lewis C. Becker, Diane M. Becker, Daniel N. Harris

المصدر: Genome Biology and Evolution

مصطلحات موضوعية: 0106 biological sciences, Most recent common ancestor, Fatty Acid Desaturases, Neanderthal, Population genetics, 01 natural sciences, Haplogroup, 0302 clinical medicine, Genetics, 0303 health sciences, education.field_of_study, biology, Hominidae, humanities, Highlights, Fatty Acids, Unsaturated, Research Article, polyunsaturated fatty acids, Human Migration, Population, Introgression, 010603 evolutionary biology, Evolution, Molecular, 03 medical and health sciences, biology.animal, evolution, Animals, Humans, Selection, Genetic, education, ancient DNA, Gene, Denisovan, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Polymorphism, Genetic, Haplotype, population genetics, biology.organism_classification, Genetic architecture, eye diseases, Siberia, Fatty acid desaturase, Ancient DNA, Evolutionary biology, Africa, biology.protein, Indians, North American, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd8231ea0785648aabaa6d1515502ddTest

7

Substrate specificity and membrane topologies of the iron-containing ω3 and ω6 desaturases from Mortierella alpina

المؤلفون: Haiqin Chen, Yong Q. Chen, Mingxuan Wang, Aisikaer Ailati, W. Todd Lowther, Floyd H. Chilton, Wei Chen

المصدر: Applied microbiology and biotechnology. 102(1)

مصطلحات موضوعية: 0301 basic medicine, Fatty Acid Desaturases, Iron, Biology, Applied Microbiology and Biotechnology, Article, Substrate Specificity, 03 medical and health sciences, Mortierella, Fatty Acids, Omega-6, Fatty Acids, Omega-3, Humans, Amino Acid Sequence, Phylogeny, chemistry.chemical_classification, Membranes, 030102 biochemistry & molecular biology, General Medicine, Cytochromes b, Sphingolipid, Eicosapentaenoic acid, Kinetics, 030104 developmental biology, Enzyme, Fatty acid desaturase, chemistry, Biochemistry, Docosahexaenoic acid, Membrane topology, biology.protein, Fatty Acids, Unsaturated, lipids (amino acids, peptides, and proteins), Function (biology), Cytochrome-B(5) Reductase, Biotechnology, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03caefc11df50ac43b3b484a3b1b3bf8Test
https://pubmed.ncbi.nlm.nih.gov/29082420Test

8

Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer

المؤلفون: Floyd H. Chilton, Tao Cui, Austin G. Hester, Elaheh Rahbar, Susan Sergeant, Timothy D. Howard, Michael C. Seeds

المصدر: The Prostate

مصطلحات موضوعية: 0301 basic medicine, Fatty Acid Desaturases, Male, medicine.medical_specialty, Urology, Single-nucleotide polymorphism, cg27386326, Biology, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Internal medicine, Genotype, medicine, arachidonic acid, Animals, Humans, Epigenetics, Allele, Aged, Genetics, chemistry.chemical_classification, food and beverages, Genetic Variation, Prostatic Neoplasms, Original Articles, Middle Aged, medicine.disease, 3. Good health, 030104 developmental biology, Fatty acid desaturase, Endocrinology, Oncology, chemistry, 030220 oncology & carcinogenesis, Multigene Family, rs174537, biology.protein, Fatty Acids, Unsaturated, omega‐6, Arachidonic acid, lipids (amino acids, peptides, and proteins), Original Article, PUFA, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c1168d5c3ef9642809c0df82f0ca53Test
https://pubmed.ncbi.nlm.nih.gov/27197070Test

9

Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome

المؤلفون: Christina E. Hugenschmidt, Barry I. Freedman, L. Douglas Case, Carl D. Langefeld, Julie T. Ziegler, Priscilla Ivester, Rasika A. Mathias, Dhananjay Vaidya, Hannah C. Ainsworth, Floyd H. Chilton, Megan E. Rudock, Donald W. Bowden, Susan Sergeant

المصدر: British Journal of Nutrition. 107:547-555

مصطلحات موضوعية: Fatty Acid Desaturases, Male, medicine.medical_specialty, FADS1, Linoleic acid, Medicine (miscellaneous), Polymorphism, Single Nucleotide, Article, Linkage Disequilibrium, White People, chemistry.chemical_compound, 8,11,14-Eicosatrienoic Acid, Delta-5 Fatty Acid Desaturase, Gene Frequency, Internal medicine, medicine, Humans, Allele frequency, Genetic Association Studies, Aged, Family Health, Metabolic Syndrome, Genetics, chemistry.chemical_classification, Arachidonic Acid, Nutrition and Dietetics, biology, Siblings, Middle Aged, medicine.disease, Eicosapentaenoic acid, United States, Black or African American, Fatty acid desaturase, Endocrinology, Diabetes Mellitus, Type 2, Eicosapentaenoic Acid, chemistry, Multigene Family, biology.protein, Female, Arachidonic acid, Metabolic syndrome, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cece72a3dd10aa9d57af43d9509c8aeTest
https://doi.org/10.1017/s0007114511003230Test

10

FADS genetic variants and ω-6 polyunsaturated fatty acid metabolism in a homogeneous island population[S]

المؤلفون: Monica Campbell, Li Gao, Floyd H. Chilton, T. Hand, Nicholas Rafaels, Carol A. Bickel, Rasika A. Mathias, Priscilla Ivester, Kathleen C. Barnes, Susan Sergeant, Candelaria Vergara

المصدر: Journal of Lipid Research, Vol 51, Iss 9, Pp 2766-2774 (2010)

مصطلحات موضوعية: Adult, Fatty Acid Desaturases, Male, genetic association, FADS1, FADS2, Population, Single-nucleotide polymorphism, QD415-436, Polymorphism, Single Nucleotide, Biochemistry, chemistry.chemical_compound, Endocrinology, Delta-5 Fatty Acid Desaturase, Fatty Acids, Omega-6, Fatty Acids, Omega-3, Humans, education, Research Articles, Aged, Genetics, chemistry.chemical_classification, education.field_of_study, biology, Geography, fatty acid desaturase, isolated population, Cell Biology, Middle Aged, Dietary Fats, Minor allele frequency, Isoenzymes, Fatty acid desaturase, Genetics, Population, chemistry, Multigene Family, biology.protein, Arachidonic acid, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a8cb5ac31b99decf853784b035bfedTest
http://www.sciencedirect.com/science/article/pii/S0022227520423077Test

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