المؤلفون: Elisabeth Obert, Cecile Nasarre, Bärbel Rohrer, Gloriane Schnabolk, Balasubramaniam Annamalai, Stephen Tomlinson, Nathaniel Parsons, Alfred S. Lewin

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 1-11 (2018)
Molecular Therapy. Methods & Clinical Development

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, genetic structures, Complement receptor 2, retinal pigment epithelium, chemical and pharmacologic phenomena, Gene delivery, choroidal neovascularization, Article, 03 medical and health sciences, Genetics, Medicine, lcsh:QH573-671, age-related macular degeneration, Molecular Biology, Retinal pigment epithelium, lcsh:Cytology, business.industry, complement factor H, AAV, Macular degeneration, medicine.disease, eye diseases, 3. Good health, Complement system, lcsh:Genetics, 030104 developmental biology, Choroidal neovascularization, medicine.anatomical_structure, Factor H, Alternative complement pathway, Cancer research, Molecular Medicine, sense organs, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1359b940954672c2132c23dd77cff65Test
https://doi.org/10.1016/j.omtm.2017.11.003Test

المؤلفون: Beth Coughlin, Mausumi Bandyopadhyay, Bärbel Rohrer, V. Michael Holers

المصدر: Journal of Ocular Pharmacology and Therapeutics. 28:402-409

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, genetic structures, Recombinant Fusion Proteins, Complement Pathway, Alternative, Angiogenesis Inhibitors, Biology, Ligands, Real-Time Polymerase Chain Reaction, Mice, Complement inhibitor, Electroretinography, medicine, Animals, Humans, Pharmacology (medical), RNA, Messenger, Receptor, Pharmacology, Lasers, Original Articles, Macular degeneration, medicine.disease, Immunohistochemistry, Choroidal Neovascularization, eye diseases, Complement system, Mice, Inbred C57BL, Ophthalmology, Vascular endothelial growth factor A, Choroidal neovascularization, Complement Factor H, Factor H, Immunology, Cancer research, Alternative complement pathway, Receptors, Complement 3d, sense organs, medicine.symptom, Biomarkers, Plasmids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36c330f00193c2382bc9921a6ff31b3Test
https://doi.org/10.1089/jop.2011.0212Test

المؤلفون: V. Michael Holers, Beth Coughlin, Steffen Thiel, Kannan Kunchithapautham, Liudmila Kulik, Bärbel Rohrer, Nicole M. Thielens, Mausumi Bandyopadhyay, Kusumam Joseph

المساهمون: Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Thomas, Frank, Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (18), pp.12753-65
Joseph, K, Kulik, L, Coughlin, B, Kunchithapautham, K, Bandyopadhyay, M, Thiel, S, Thielens, N M, Holers, V M & Rohrer, B 2013, ' Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner ', Journal of Biological Chemistry, vol. 288, no. 18, pp. 12753-65 . https://doi.org/10.1074/jbc.M112.421891Test
Journal of Biological Chemistry, 2013, 288 (18), pp.12753-65

مصطلحات موضوعية: MESH: Complement Pathway, Mannose-Binding Lectin, MESH: Complement C1q, genetic structures, Complement Pathway, Alternative, Retinal Pigment Epithelium, Biochemistry, MESH: Mice, Knockout, Mice, 0302 clinical medicine, MESH: Oxidants, MESH: Animals, Complement C1q, Phospholipids, Mannan-binding lectin, Mice, Knockout, 0303 health sciences, MESH: Oxidative Stress, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Oxidants, MESH: Immunoglobulin M, MESH: Retinal Pigment Epithelium, 3. Good health, Cell biology, Lectin pathway, Factor H, MESH: Hydrogen Peroxide, Ficolin, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Immunology, Biology, Cell Line, 03 medical and health sciences, MESH: Homeodomain Proteins, Animals, Humans, Molecular Biology, MESH: Mice, 030304 developmental biology, Homeodomain Proteins, MESH: Phospholipids, MESH: Humans, Complement Pathway, Mannose-Binding Lectin, Cell Biology, Hydrogen Peroxide, eye diseases, Complement system, MESH: Cell Line, Oxidative Stress, Immunoglobulin M, 030221 ophthalmology & optometry, Alternative complement pathway, sense organs, Complement membrane attack complex, MESH: Complement Pathway, Alternative

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac7a4b3de08eedf1fcfd9d4711a76f1Test
https://hal.univ-grenoble-alpes.fr/hal-01322432Test

المؤلفون: Beth Coughlin, Qin Long, Yuxiang Huang, Joshua M. Thurman, Viviana P. Ferreira, Michael K. Pangburn, Kannan Kunchithapautham, V. Michael Holers, Gary S. Gilkeson, Stephen Tomlinson, Bärbel Rohrer, Brandon Renner

المصدر: Advances in Experimental Medicine and Biology ISBN: 9781441956347

مصطلحات موضوعية: genetic structures, Complement receptor 2, Angiogenesis, Biology, Macular degeneration, medicine.disease, eye diseases, Complement system, Choroidal neovascularization, Factor H, Immunology, Alternative complement pathway, Cancer research, medicine, sense organs, medicine.symptom, Complement membrane attack complex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5eaea8a94e1e872ce0e4aff09c991698Test
https://doi.org/10.1007/978-1-4419-5635-4_10Test