التفاصيل البيبلوغرافية
| العنوان: |
Intranasal oxytocin increases state anhedonia following imagery training of positive social outcomes in individuals lower in extraversion, trust-altruism, and openness to experience. |
| المؤلفون: |
Wong, Shiu F.1 (AUTHOR) shiu.wong@concordia.ca, Vaillancourt, Serena1 (AUTHOR), Grossman, Shawna1 (AUTHOR), Kelly-Turner, Kenneth1 (AUTHOR), Blackwell, Simon E.2 (AUTHOR), Ellenbogen, Mark A.1 (AUTHOR) |
| المصدر: |
International Journal of Psychophysiology. Jul2021, Vol. 165, p8-17. 10p. |
| مصطلحات موضوعية: |
*EXTRAVERSION, *ANHEDONIA, *OXYTOCIN, *OPENNESS to experience, *MENTAL imagery, *PERSONALITY, *SOCIAL contact |
| مستخلص: |
Psychological disorders such as major depressive disorder are characterised by interpersonal difficulties and anhedonia. A cognitive mechanism proposed to contribute to the maintenance of these problems is a diminished ability to generate positive mental imagery, especially regarding social interactions. The current study examined whether the effects of social imagery training on social activity and anhedonia could be enhanced with the addition of intranasal oxytocin, and whether these effects might be augmented in persons with a high propensity to engage socially (i.e., high extraversion). University students (N = 111) were randomised to self-administer intranasal oxytocin or placebo, followed by a single session of positive social or non-social imagery training that required participants to imagine 64 positive scenarios occurring in either a social or non-social context, respectively. There were no main effects of imagery type and drug, and no interaction effect on anhedonia and social activity, measured respectively via self-report and a behavioural task. Individuals low in extraversion, trust-altruism, and openness to experience reported significantly more anhedonia after receiving oxytocin relative to placebo, but only following imagery training of positive social outcomes. Results highlight the negative consequences of increasing oxytocin bioavailability after priming social contact in more withdrawn individuals. • We combined imagery training for positive social outcomes with oxytocin to alleviate anhedonia. • No significant main or interaction effects on behavioural and self-report measures of anhedonia • Personality traits moderated the effect of oxytocin and social imagery on state anhedonia. • Low extraversion, trust-altruism, and openness predicted more anhedonia after this combination. • Oxytocin and social priming in those with low social affiliation traits has detrimental effects. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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