Interplay between inflammation and cancer
| العنوان: | Interplay between inflammation and cancer |
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| المؤلفون: | Igor Piotrowski, Wiktoria Maria Suchorska, Katarzyna Kulcenty |
| المصدر: | Reports of Practical Oncology and Radiotherapy |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Angiogenesis, STAT3, signal transducer and activator of transcription 3, NFκB, nuclear factor kappa-light-chain-enhancer of activated B cells, Original research article, PTHrP, parathyroid hormone related protein, MPO, myeloperoxidase, CDH1, cadherin 1, 030218 nuclear medicine & medical imaging, TNF-α, tumour necrosis factor α, 0302 clinical medicine, GI, gastrointensinal cancer, TNFR2, Tumor necrosis factor receptor 2, Cancer, TGF-β, transforming growth factor β, ROS, reactive oxigen species, EP, receptor - prostaglandin receptor, NSAIDs, non-steroidal anti-inflammatory drugs, Extravasation, IL-6, interleukin 6, Oncology, NADPH, nicotynamide adenine dinucleotide phosphate hydrogen, 030220 oncology & carcinogenesis, iNOS, inducible nitric oxide synthase, medicine.symptom, ANGPTL4, angiopoietin-like 4, Inflammation, NK, natural killer cells, RNS, reactive nitrogen species, 03 medical and health sciences, Immune system, medicine, PGE2, prostaglandin E2, Radiology, Nuclear Medicine and imaging, Neoplastic transformation, TGFBRII, transforming growth factor, beta receptor II, EMT, epithelail to mesenchymal transition, NO, nitric oxide, Innate immune system, business.industry, medicine.disease, Tumor reccurence, TNFR1, Tumor necrosis factor receptor 1, bFGF, fibroblast growth factor, COX, cyclooxygenase, Cancer research, business, Wound healing, VEGF, vascular endothelail growth factor |
| الوصف: | Tumor-promoting inflammation is one of the hallmarks of cancer. It has been shown that cancer development is strongly influenced by both chronic and acute inflammation process. Progress in research on inflammation revealed a connection between inflammatory processes and neoplastic transformation, the progression of tumour, and the development of metastases and recurrences. Moreover, the tumour invasive procedures (both surgery and biopsy) affect the remaining tumour cells by increasing their survival, proliferation and migration. One of the concepts explaining this phenomena is an induction of a wound healing response. While in normal tissue it is necessary for tissue repair, in tumour tissue, induction of adaptive and innate immune response related to wound healing, stimulates tumour cell survival, angiogenesis and extravasation of circulating tumour cells. It has become evident that certain types of immune response and immune cells can promote tumour progression more than others. In this review, we focus on current knowledge on carcinogenesis and promotion of cancer growth induced by inflammatory processes. |
| اللغة: | English |
| تدمد: | 2083-4640 1507-1367 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf716b2f37949b02e2980273a453ab9eTest http://europepmc.org/articles/PMC7191124Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bf716b2f37949b02e2980273a453ab9e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20834640 15071367 |
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