التفاصيل البيبلوغرافية
| العنوان: |
The nucleus reuniens, a thalamic relay for cortico-hippocampal interaction in recent and remote memory consolidation. |
| المؤلفون: |
Ferraris, Maëva1 (AUTHOR), Cassel, Jean-Christophe2,3 (AUTHOR), Pereira de Vasconcelos, Anne2,3 (AUTHOR), Stephan, Aline2,3 (AUTHOR), Quilichini, Pascale P1 (AUTHOR) pascale.quilichini@univ-amu.fr |
| المصدر: |
Neuroscience & Biobehavioral Reviews. Jun2021, Vol. 125, p339-354. 16p. |
| مصطلحات موضوعية: |
*PREFRONTAL cortex, *EXPLICIT memory, *SPATIAL memory, *THALAMIC nuclei, *MEMORY, *MEMORY trace (Psychology) |
| مستخلص: |
• System-level consolidation of declarative memories involves a dialogue between the hippocampus and the medial prefrontal cortex during sleep. • The cortico-hippocampal dialogue is supported by the synchronization through different network oscillations and recruitment of information-relevant cell assemblies. • The thalamic nucleus reuniens, anatomical hub between the hippocampus and the medial prefrontal cortex, is involved in different recent and remote memory consolidation. • The cortico-thalamic-hippocampal network appears necessary to support remote spatial memory consolidation. • The cortico-thalamic-hippocampal network also participates to the persistence of aversive memory. • Some insights on the possible mechanisms regarding the influence of the nucleus reuniens on the cortico-hippocampal coupling in the context of memory persistence are discussed. The consolidation of declarative memories is believed to occur mostly during sleep and involves a dialogue between two brain regions, the hippocampus and the medial prefrontal cortex. The information encoded during experience by neuronal assemblies is replayed during sleep leading to the progressive strengthening and integration of the memory trace in the prefrontal cortex. The gradual transfer of information from the hippocampus to the medial prefrontal cortex for long-term storage requires the synchronization of cortico-hippocampal networks by different oscillations, like ripples, spindles, and slow oscillations. Recent studies suggest the involvement of a third partner, the nucleus reuniens, in memory consolidation. Its bidirectional connections with the hippocampus and medial prefrontal cortex place the reuniens in a key position to relay information between the two structures. Indeed, many topical works reveal the original role that the nucleus reuniens occupies in different recent and remote memories consolidation. This review aimed to examine these contributions, as well as its functional embedment in this complex memory network, and provide some insights on the possible mechanisms. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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