المؤلفون: Tan, Justin L, Fogley, Rachel D, Flynn, Ryan A, Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi Peng, T., Brian, Laga, Alvaro C, Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B, Kim, Yoon Jung, Clohessy, John G, Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E, van Rooijen, Ellen, Hagedorn, Elliott J, Shyh-Chang, Ng, White, Richard M, Price, David H, Pandolfi, Pier Paolo, Peterlin, B Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M, Chang, Howard Y, Young, Richard A, Zon, Leonard I

المصدر: Molecular Cell. 62(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, Oncology and Carcinogenesis, Biotechnology, Cancer, Genetics, Aetiology, 2.1 Biological and endogenous factors, Animals, Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Humans, Melanoma, Melanoma, Experimental, Oncogene Proteins, Positive Transcriptional Elongation Factor B, Pyrimidines, RNA-Binding Proteins, Transcription Factors, Transcription, Genetic, Tumor Suppressor Proteins, Zebrafish, Zebrafish Proteins, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/05k7h255Test

المؤلفون: Tan, Justin l., Fogley, Rachel d., Flynn, Ryan a., Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi peng, Do, Brian t., Laga, Alvaro c., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste b., Kim, Yoon jung, Clohessy, John g., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John e., Van rooijen, Ellen, Hagedorn, Elliott j., Shyh-Chang, Ng, White, Richard m., Price, David h., Pandolfi, Pier paolo, Peterlin, B. matija, Zhou, Yi, Kim, Tae-Hoon, Asara, John m., Chang, Howard y., Young, Richard a., Zon, Leonard i.

المساهمون: Harvard Stem Cell Institute Cambridge, USA (HSCI), Harvard University, Howard Hughes Medical Institute Boston (HHMI), Howard Hughes Medical Institute (HHMI)-Harvard Medical School Boston (HMS), Boston Children's Hospital, Harvard Medical School Boston (HMS), Dana-Farber Cancer Institute Boston, Center for Personal Dynamic Regulomes Stanford (CPDR), Stanford Medicine, Stanford University-Stanford University, Whitehead Institute, Massachusetts Institute of Technology (MIT), Department of Biology MIT Cambridge, USA, Brigham & Women’s Hospital Boston (BWH), University of California San Francisco (UC San Francisco), University of California (UC), Yale School of Medicine New Haven, Connecticut (YSM), University of Texas at Dallas Richardson (UT Dallas), Beth Israel Deaconess Medical Center Boston (BIDMC), Cancer Research Institute Boston, USA, Harvard Medical School Boston (HMS)-Harvard Medical School Boston (HMS), University of Iowa Iowa City, Genome Institute of Singapore (GIS), Memorial Sloane Kettering Cancer Center New York, Weill Medical College of Cornell University New York, This work was supported by the Howard Hughes Medical Institute and the National Cancer Institute (NIH) R01CA103846 (to L.I.Z.). L.I.Z. is a founder and stockholder of Fate, Inc., Scholar Rock, and a scientific advisor for Stemgent. J.L.T. is an Agency for Science, Technology & Research, Singapore National Science Scholarship recipient. C.B.G. is a PhRMA Foundation predoctoral fellow. R.A.Y. is a founder and stockholder of Syros Pharmaceuticals. This work was partially supported by NIH grants 2P01CA120964 (to J.M.A.), 5P30CA006516 (to J.M.A.), R01CA140485 (to T.H.K.), R21AI107067 (to T.H.K.), R01-ES023168 (to H.Y.C), and R01-HG004361 (to H.Y.C), We thank Min Yuan for her help with the metabolomics studies and Dr. Telmo Henriques for his advice on RNA assays.

المصدر: ISSN: 1097-2765.

مصطلحات موضوعية: MESH: Animals, MESH: Cell Line, Tumor, MESH: Pyrimidines / metabolism, MESH: RNA-Binding Proteins / genetics, MESH: RNA-Binding Proteins / metabolism, MESH: Transcription, Genetic, MESH: Tumor Suppressor Proteins / genetics, MESH: Zebrafish / genetics, MESH: Zebrafish Proteins / genetics, MESH: Zebrafish Proteins / metabolism, MESH: Gene Expression Regulation, Neoplastic, MESH: Humans, MESH: Melanoma / genetics, MESH: Melanoma / metabolism, MESH: Melanoma / pathology, MESH: Melanoma, Experimental, MESH: Oncogene Proteins / genetics, MESH: Positive Transcriptional Elongation Factor B / genetics, [SDV]Life Sciences [q-bio], [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27058786; pasteur-02871949; https://pasteur.hal.science/pasteur-02871949Test; PUBMED: 27058786; PUBMEDCENTRAL: PMC4836061

الإتاحة: https://doi.org/10.1016/j.molcel.2016.03.013Test
https://pasteur.hal.science/pasteur-02871949Test