Muscle Response to the Association of Statin and Physical Exercise in Rats
| العنوان: | Muscle Response to the Association of Statin and Physical Exercise in Rats |
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| المؤلفون: | Susimary Aparecida Trevizan Padulla, José Carlos Silva Camargo Filho, Mariana Rotta Bonfim, Marilita Falângola Accioly, Reinaldo Azoubel, Luiz Carlos Marques Vanderlei, Dorotéia Rossi Silva Souza |
| المساهمون: | Universidade Estadual Paulista (Unesp), Fac Med Sao Jose Rio Preto |
| المصدر: | International Journal of Morphology v.27 n.4 2009 SciELO Chile CONICYT Chile instacron:CONICYT Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| بيانات النشر: | SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Skeletal Muscle, business.industry, Muscle response, Medicine, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Anatomy, business, Exercise, Humanities |
| الوصف: | Made available in DSpace on 2013-08-12T18:25:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 Made available in DSpace on 2013-09-30T18:09:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:23:19Z No. of bitstreams: 0 Made available in DSpace on 2014-05-20T13:23:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 Physical exercise and statins, which are recommended for the treatment of dyslipidemia, are independently associated to the occurrence of muscle injury. The objective is analyze the effect of aerobic exercise associated to the use of simvastatin on the morphology of the gastrocnemius muscle. Thirty Wistar rats were divided into six groups, two of which received a standard diet (1 sedentary and 1 exercised) and four (1 sedentary with medication, 1 sedentary without medication, 1 exercised with medication, 1 exercised without medication) received a hypercholesterolemic diet (standard diet with the addition of cholesterol and coconut oil). Simvastatin (20 mg/Kg) was administered five days a week for eight weeks, together with aerobic training on a treadmill (9.75 m/min) for 60 minutes a day. The gastrocnemius muscle was removed, sliced, stained with Hematoxylin-Eosin and submitted to a histochemical reaction to determine mitochondrial activity. The data were analyzed using a paired t-test, analysis of variance and Scheffe's post hoc test (p |
| وصف الملف: | text/html |
| تدمد: | 0717-9502 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47a28b1457b40bd97bf90b3105fb0c1Test https://doi.org/10.4067/s0717-95022009000400031Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e47a28b1457b40bd97bf90b3105fb0c1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 07179502 |
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