دورية أكاديمية

Au-Decorated N‑Rich Carbon Dots as Peroxidase Mimics for the Detection of Acetylcholinesterase Activity

التفاصيل البيبلوغرافية
العنوان: Au-Decorated N‑Rich Carbon Dots as Peroxidase Mimics for the Detection of Acetylcholinesterase Activity
المؤلفون: Dingding Zhang (217863), Qingyi Han (11994108), Wendong Liu (507488), Keying Xu (10822626), Mingzheng Shao (11994111), Yuyan Li (574899), Peiyao Du (8849297), Zhen Zhang (86004), Bingsi Liu (11994114), Libing Zhang (1481890), Xiaoquan Lu (1427404)
سنة النشر: 1753
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Evolutionary Biology, Ecology, Hematology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rich carbon dot, possess excellent stability, distributed metals anchored, clinical serum analysis, based colorimetric biosensor, acetylcholinesterase activity well, work paves, transfer process, successfully developed, successful preparation, substrate due, sensing applications, potential application, peroxidase mimics, mimicking activity, ideal performance, high sensitivity, high affinity, free surface, fast electron, effective catalysts
الوصف: Well-distributed metals anchored on supports have attracted great attention owing to their potential application as cost-effective catalysts. Here, we demonstrate the successful preparation of Au-decorated N-rich carbon dot (Au-CD) nanocomposites, which possess excellent stability in aqueous media. The Au-CDs exhibit remarkable peroxidase-mimicking activity and high affinity to the substrate due to the fast electron-transfer process and ligand-free surface. Based on this, an Au-CD nanozyme-based colorimetric biosensor was successfully developed to assess the activity of acetylcholinesterase with high sensitivity and selectivity. More importantly, an ideal performance was achieved in clinical serum analysis. This work paves the way for the development of well-distributed metals anchored on supports as nanozymes for sensing applications.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
العلاقة: https://figshare.com/articles/journal_contribution/Au-Decorated_N_Rich_Carbon_Dots_as_Peroxidase_Mimics_for_the_Detection_of_Acetylcholinesterase_Activity/19025004Test
DOI: 10.1021/acsanm.1c03613.s001
الإتاحة: https://doi.org/10.1021/acsanm.1c03613.s001Test
حقوق: CC BY-NC 4.0
رقم الانضمام: edsbas.73FBA0DE
قاعدة البيانات: BASE