التفاصيل البيبلوغرافية
| العنوان: |
Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe |
| المؤلفون: |
Wernly, Bernhard, Artigas, Antonio, Bollen Pinto, Bernardo, Schefold, Joerg C., Beil, Michael, van Heerden, Peter Vernon, Zafeiridis, Tilemachos, Andersen, Finn H., Moreno, Rui, Boumendil, Ariane, De Lange, Dylan W., Flaatten, Hans, Eller, Philipp, Joannidis, Michael, Mesotten, Dieter, Reper, Pascal, Oeyen, Sandra, Swinnen, Walter, Brix, Helene, Brushoej, Jens, Villefrance, Maja, Nedergaard, Helene Korvenius, Bjerregaard, Anders Thais, Balleby, Ida Riise, Andersen, Kasper, Hansen, Maria Aagaard, Uhrenholt, Stine, Bundgaard, Helle, Fjølner, Jesper, Mohamed, Aliae AR Hussein, Salah, Rehab, Ali, Yasmin Khairy NasrEldin Mohamed, Wassim, Kyrillos, Elgazzar, Yumna A, Tharwat, Samar, Azzam, Ahmed Y, Habib, Ayman abdelmawgoad, Abosheaishaa, Hazem Maarouf, Azab, Mohammed A, Leaver, Susannah, Galbois, Arnaud, Guidet, Bertrand, Charron, Cyril, Guerot, Emmanuel, Besch, Guillaume, Rigaud, Jean-Philippe, Maizel, Julien, Djibré, Michel, Burtin, Philippe, Garcon, Pierre, Nseir, Saad, Valette, Xavier, Alexandru, Nica, Marin, Nathalie, Vaissiere, Marie, Plantefeve, Gaëtan, Vanderlinden, Thierry, Jurcisin, Igor, Megarbane, Buno, Caillard, Anais, Valent, Arnaud, Garnier, Marc, Besset, Sebastien, Oziel, Johanna, Raphaelen, Jean-herlé, Dauger, Stéphane, Dumas, Guillaume, Goncalves, Bruno, Piton, Gaël, Jung, Christian, Bruno, Raphael Romano, Kelm, Malte, Wolff, Georg, Goebel, Ulrich, Barth, Eberhard, Kunstein, Anselm, Schuster, Michael, Welte, Martin, Lutz, Matthias, Meybohm, Patrick, Steiner, Stephan, Poerner, Tudor, Haake, Hendrik, Schaller, Stefan, Kindgen-Milles, Detlef, Meyer, Christian, Kurt, Muhammed, Kuhn, Karl Friedrich, Randerath, Winfried, Wollborn, Jakob, Dindane, Zouhir, Kabitz, Hans-Joachim, Voigt, Ingo, Shala, Gonxhe, Rovina, Nikoletta, Aidoni, Zoi, Chrisanthopoulou, Evangelia, Papadogoulas, Antonios, Gurjar, Mohan, Mahmoodpoor, Ata, Ahmed, Abdullah Khudhur, Marsh, Brian, Elsaka, Ahmed, Sviri, Sigal, Comellini, Vittoria, Rabha, Ahmed, Ahmed, Hazem, Namendys-Silva, Silvio a, Ghannam, Abdelilah, Groenendijk, Martijn, Zegers, Marieke, de Lange, Dylan, Cornet, Alex, Evers, Mirjam, Haas, Lenneke, Dormans, Tom, Dieperink, Willem, Romundstad, Luis, Sjøbø, Britt, Andersen, Finn H, Strietzel, Hans Frank, Olasveengen, Theresa, Hahn, Michael, Czuczwar, Miroslaw, Gawda, Ryszard, Klimkiewicz, Jakub, de LurdesSantos, Maria Campos, Gordinho, André, Santos, Henrique, Assis, Rui, Oliveira, Ana Isabel Pinho, Badawy, Mohamed Raafat, Perez-Torres, David, Gomà, Gemma, Villamayor, Mercedes Ibarz, Mira, Angela Prado, Cubero, Patricia Jimeno, Rivera, Susana Arias, Tomasa, Teresa, Iglesias, David, Vázquez, Eric Mayor, Aldecoa, Cesar, Ferreira, Aida Fernández, Zalba-Etayo, Begoña, Canas-Perez, Isabel, Tamayo-Lomas, Luis, Diaz-Rodriguez, Cristina, Sancho, Susana, Priego, Jesús, Abualqumboz, Enas M.Y., Hilles, Momin Majed Yousuf, Saleh, Mahmoud, Ben-HAmouda, Nawfel, Roberti, Andrea, Dullenkopf, Alexander, Fleury, Yvan, Pinto, Bernardo Bollen, Schefold, Joerg C, Al-Sadawi, Mohammed, Serck, Nicolas, Dewaele, Elisabeth, Kumar, Pritpal, Bundesen, Camilla, Innes, Richard, Gooch, James, Cagova, Lenka, Potter, Elizabeth, Reay, Michael, Davey, Miriam, Humphreys, Sally, Berlemont, Caroline Hauw, Chousterman, Benjamin Glenn, Dépret, François, Ferre, Alexis, Vettoretti, Lucie, Thevenin, Didier, Faltlhauser, Andreas, Milovanovic, Milena, Simon, Philipp, Lorenz, Marco, Stoll, Sandra Emily, Dubler, Simon, Fuest, Kristina, Mulita, Francesk, Kondili, Eumorifa, Andrianopoulos, Ioannis, Meynaar, Iwan, Cornet, Alexander Daniel, Sjøbøe, Britt, Kluzik, Anna, Zatorski, Paweł, Drygalski, Tomasz, Szczeklik, Wojciech, Solek-pastuszka, Joanna, Onichimowski, Dariusz, Stefaniak, Jan, Stefanska-Wronka, Karina, Zabul, Ewa, Cardoso, Filipe Sousa, Banzo, Maria José Arche, Tomasa-Irriguible, Teresa Maria, Mira, Ángela Prado, Arias-Rivera, Susana, Frutos-Vivar, Fernando, Lopez-Cuenca, Sonia, de Gopegui, Pablo Ruiz, Abidi, Nour, Chau, Ivan, Pugh, Richard, Smuts, Sara |
| المصدر: |
http://lobid.org/resources/99370670818906441Test#!, 25(1):344. |
| سنة النشر: |
2021 |
| المجموعة: |
Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| مصطلحات موضوعية: |
COVID-19, Aged, 80 and over [MeSH], Aged [MeSH], Frail Elderly [MeSH], COVID-19/mortality [MeSH], Critical Illness/mortality [MeSH], Male [MeSH], Intensive Care Units [MeSH], Pneumonia, Viral/virology [MeSH], Comorbidity [MeSH], Frailty, Surges, Pandemia, SARS-CoV-2 [MeSH], Female [MeSH], Outcome, Elderly, Humans [MeSH], Prospective Studies [MeSH], Survival Analysis [MeSH], Europe/epidemiology [MeSH], Pandemics [MeSH], Viral/mortality [MeSH], Organ Dysfunction Scores [MeSH], Research |
| الوصف: |
Background!#!The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe.!##!Methods!#!This was a prospective European observational study (the COVIP study) in ICU patients aged 70 years and older admitted with COVID-19 disease from March to December 2020 to 159 ICUs in 14 European countries. An electronic database was used to register a number of parameters including: SOFA score, Clinical Frailty Scale, co-morbidities, usual ICU procedures and survival at 90 days. The study was registered at ClinicalTrials.gov (NCT04321265).!##!Results!#!In total, 2625 patients were included, 1327 from the first and 1298 from the second surge. Median age was 74 and 75 years in surge 1 and 2, respectively. SOFA score was higher in the first surge (median 6 versus 5, p < 0.0001). The PaO!##!Conclusion!#!An unexpected, but significant, decrease in 30-day and 90-day survival was observed during the second surge in our cohort of elderly ICU patients. The reason for this is unclear. Our main concern is whether the widespread changes in practice and treatment of COVID-19 between the two surges have contributed to this increased mortality in elderly patients. Further studies are urgently warranted to provide more evidence for current practice in elderly patients.!##!Trial registration number!#!NCT04321265 , registered March 19th, 2020. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| ردمك: |
978-9937-0-6708-9
9937-0-6708-1 |
| العلاقة: |
https://repository.publisso.de/resource/frl:6463929Test; https://doi.org/10.1186/s13054-021-03739-7Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459701Test/ |
| DOI: |
10.1186/s13054-021-03739-7 |
| الإتاحة: |
https://doi.org/10.1186/s13054-021-03739-7Test
https://repository.publisso.de/resource/frl:6463929Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459701Test/ |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.620F5E06 |
| قاعدة البيانات: |
BASE |
