دورية أكاديمية
Epilepsy and Sex Hormones
| العنوان: | Epilepsy and Sex Hormones |
|---|---|
| المؤلفون: | Emine GENÇ, Bülent Oğuz GENÇ |
| المصدر: | Archives of Epilepsy, Vol 24, Iss 1, Pp 6-9 (2018) |
| بيانات النشر: | Galenos Yayinevi, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system LCC:Medicine |
| مصطلحات موضوعية: | epilepsy, neurosteroids, estrogen, progesterone, sex hormones, testosterone, Neurology. Diseases of the nervous system, RC346-429, Medicine |
| الوصف: | There is a mutual interaction between sex steroid hormones and epilepsy. Although female and male sex hormones and their metabolites access the brain via the blood brain barrier, they can also be synthesized de novo from cholesterol within the glia and neurones (neurosteroids). While estrogens enhance neuronal excitability, progesterone and its metabolites exert anticonvulsant effects. Testosterone, on the other hand, has a less consistent effect on seizure susceptibility, depending on the ratio of its conversion to estrogens. This paper focuses on the effects of neurosteroidal sex hormones on seizure susceptibility. Further study is required to identify the future role of their use in the treatment of epilepsy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2792-0550 |
| العلاقة: | http://archepilepsy.org/archives/archive-detail/article-preview/epilepsy-and-sex-hormones/54920Test; https://doaj.org/toc/2792-0550Test |
| DOI: | 10.14744/epilepsi.2018.42204 |
| الوصول الحر: | https://doaj.org/article/ce5d695c36eb4381bc6509a3ce69e79dTest |
| رقم الانضمام: | edsdoj.5d695c36eb4381bc6509a3ce69e79d |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 27920550 |
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| DOI: | 10.14744/epilepsi.2018.42204 |