المؤلفون: Michela Verzè, Elisa Giovannetti, Alessandro Leonetti, Amir Avan, Roberta Minari, Alessandro Gregori, Mjriam Capula, Filippo Papini, Paola Bordi, Giulia Mazzaschi, Btissame El Hassouni, Marcello Tiseo

المساهمون: Medical oncology laboratory, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: Cells, 10(6):1520. MDPI Multidisciplinary Digital Publishing Institute
Leonetti, A, Capula, M, Minari, R, Mazzaschi, G, Gregori, A, el Hassouni, B, Papini, F, Bordi, P, Verzè, M, Avan, A, Tiseo, M & Giovannetti, E 2021, ' Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs ', Cells, vol. 10, no. 6, 1520 . https://doi.org/10.3390/cells10061520Test
Cells
Cells, Vol 10, Iss 1520, p 1520 (2021)
Volume 10
Issue 6

مصطلحات موضوعية: Oncology, Circulating mirnas, Male, Lung Neoplasms, medicine.medical_treatment, Drug Resistance, Disease, Targeted therapy, Basal (phylogenetics), EGFR‐mutated NSCLC, Carcinoma, Non-Small-Cell Lung, Medicine, Biology (General), Non-Small-Cell Lung, Tumor, Gefitinib, General Medicine, Middle Aged, targeted therapy, Response to EGFR‐TKI, response to EGFR-TKI, ErbB Receptors, Female, EGFR-mutated NSCLC, Adult, medicine.medical_specialty, QH301-705.5, Antineoplastic Agents, Afatinib, Article, Erlotinib Hydrochloride, Statistical significance, Internal medicine, microRNA, Biomarkers, Tumor, Humans, Circulating MicroRNA, MiRNA, Aged, Drug Resistance, Neoplasm, MicroRNAs, Mutation, Protein Kinase Inhibitors, Retrospective Studies, miRNA, business.industry, Carcinoma, Retrospective cohort study, Fold change, respiratory tract diseases, Neoplasm, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b195378c54aaed1b56ebdc037e6b7173Test
https://research.vumc.nl/en/publications/9f10a1ce-6a0e-421a-b323-08d160a0846fTest

المؤلفون: Yves Mentens, Jose Ferri, Godefridus J. Peters, Elisa Giovannetti, Nele Van Der Steen, Paul Germonpré, M. Ramael, Patrick Pauwels, Leticia G. Leon, David R. Gandara, Christian Rolfo

المساهمون: CCA - Cancer biology and immunology, Medical oncology laboratory, Medical oncology, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: Van Der Steen, N, Mentens, Y, Ramael, M, Leon, L G, Germonpré, P, Ferri, J, Gandara, D R, Giovannetti, E, Peters, G J, Pauwels, P & Rolfo, C 2018, ' Double Trouble : A Case Series on Concomitant Genetic Aberrations in NSCLC ', Clinical Lung Cancer, vol. 19, no. 1, pp. 35-41 . https://doi.org/10.1016/j.cllc.2017.06.010Test
Clinical Lung Cancer, 19(1), 35-41. Elsevier
Clinical lung cancer

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Viral Oncogene, medicine.disease_cause, Targeted therapy, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Exon, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Genetic Testing, Molecular Targeted Therapy, Epidermal growth factor receptor, Neoplasm Metastasis, Lung cancer, Genetic testing, biology, medicine.diagnostic_test, business.industry, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, ErbB Receptors, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Female, Human medicine, KRAS, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184d2225d523195834ff5aba158882edTest
https://doi.org/10.1016/j.cllc.2017.06.010Test

المؤلفون: Elisa Giovannetti, Vanesa Gregorc, Chiara Lazzari, Maria Giulia Cangi, Mariacarmela Santarpia, Alessandra Bulotta

المصدر: Lazzari, C, Gregorc, V, Cangi, M G, Giovannetti, E, Bulotta, A & Santarpia, M 2018, ' Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer ', Journal of Thoracic Disease, vol. 10, pp. S4023-S4027 . https://doi.org/10.21037/jtd.2018.10.17Test
Journal of thoracic disease (Online) 10 (2018): S4023–S4027. doi:10.21037/jtd.2018.10.17
info:cnr-pdr/source/autori:Lazzari C.; Gregorc V.; Cangi M.G.; Giovannetti E.; Bulotta A.; Santarpia M./titolo:Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer/doi:10.21037%2Fjtd.2018.10.17/rivista:Journal of thoracic disease (Online)/anno:2018/pagina_da:S4023/pagina_a:S4027/intervallo_pagine:S4023–S4027/volume:10

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, Lung Neoplasms, DNA Mutational Analysis, Antineoplastic Agents, Exosomes, Sensitivity and Specificity, Circulating Tumor DNA, Epidermal growth factor, Carcinoma, Non-Small-Cell Lung, medicine, ROS1, Biomarkers, Tumor, Anaplastic lymphoma kinase, Humans, Mutation detection, Lung cancer, Aged, Acrylamides, business.industry, Liquid Biopsy, RNA, Genes, erbB-1, Middle Aged, medicine.disease, ErbB Receptors, Editorial, Pyrimidines, Circulating tumor DNA, Cancer research, Female, Non small cell, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85b54e65ba6cced812d1e88976ca0d2Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057399178&origin=inwardTest

المؤلفون: Henk L. Dekker, Elisa Giovannetti, Marcello Tiseo, Patrick Pauwels, Filip Lardon, Christian Rolfo, Kaylee Keller, Rob Ruijtenbeek, Alessandro Leonetti, Niccola Funel, Godefridus J. Peters, Nele Van Der Steen

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology

المصدر: Biochemical pharmacology
van der Steen, N, Leonetti, A, Keller, K, Dekker, H, Funel, N, Lardon, F, Ruijtenbeek, R, Tiseo, M, Rolfo, C, Pauwels, P, Peters, G J & Giovannetti, E 2019, ' Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line ', Biochemical Pharmacology, vol. 166, pp. 128-138 . https://doi.org/10.1016/j.bcp.2019.05.014Test
Biochemical Pharmacology, 166, 128-138. Elsevier Inc.

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Lung Neoplasms, Antineoplastic Agents, Biochemistry, 03 medical and health sciences, Erlotinib Hydrochloride, 0302 clinical medicine, Crizotinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Epidermal growth factor receptor, Phosphorylation, Lung cancer, Protein kinase B, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Aged, Pharmacology, biology, Chemistry, Pharmacology. Therapy, Drug Synergism, Cell cycle, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Erlotinib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198c1da7976161631dcc7ca088486798Test
https://hdl.handle.net/10067/1611930151162165141Test

المؤلفون: Marcello Tiseo, Godefridus J. Peters, Paul Germonpré, Christian Rolfo, Nele Van Der Steen, Christophe Hermans, Giulia Mazzaschi, Elisa Giovannetti, Karen Zwaenepoel, Daan P. Geerke, Patrick Pauwels, Paul Van Schil, Ken Op de Beeck, Filip Lardon, Rosa A. Luirink

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Imaging and biomarkers, AIMMS, Molecular and Computational Toxicology

المصدر: Molecules
Volume 24
Issue 24
Molecules: a journal of synthetic chemistry and natural product chemistry
Molecules, 24(24). Multidisciplinary Digital Publishing Institute
van der Steen, N, Zwaenepoel, K, Mazzaschi, G, A Luirink, R, P Geerke, D, op de Beeck, K, Hermans, C, Tiseo, M, van Schil, P, Lardon, F, Germonpré, P, Rolfo, C, Giovannetti, E, J Peters, G & Pauwels, P 2019, ' The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies ', Molecules, vol. 24, no. 24 . https://doi.org/10.3390/molecules24244443Test
Molecules, 24(24):4443. Multidisciplinary Digital Publishing Institute (MDPI)
Van Der Steen, N, Zwaenepoel, K, Mazzaschi, G, Luirink, R A, Geerke, D P, De Beeck, K O, Hermans, C, Tiseo, M, Van Schil, P, Lardon, F, Germonpré, P, Rolfo, C, Giovannetti, E, Peters, G J & Pauwels, P 2019, ' The role of c-met as a biomarker and player in innate and acquired resistance in non-small-cell lung cancer : Two new mutations warrant further studies ', Molecules, vol. 24, no. 24, 4443 . https://doi.org/10.3390/molecules24244443Test

مصطلحات موضوعية: Male, Lung Neoplasms, Mutant, Pharmaceutical Science, NSCLC, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Epidermal growth factor receptor, Neoplasm Metastasis, Receptor, 0303 health sciences, biology, Middle Aged, Proto-Oncogene Proteins c-met, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, Chemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, Biomarker (medicine), Female, Antibody, Adult, C-Met, EGFR, Article, Deep sequencing, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Biomarkers, Tumor, medicine, Humans, Physical and Theoretical Chemistry, Lung cancer, Biology, Aged, 030304 developmental biology, business.industry, Organic Chemistry, Gene Amplification, medicine.disease, chemistry, Drug Resistance, Neoplasm, Mutation, biology.protein, Cancer research, Tumor Suppressor Protein p53, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41c017861e5a2eba24b3519c13c0ba8Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85076355617&origin=inwardTest

المؤلفون: O. W. M. Meijer, Geertjan van Tienhoven, Henk M.W. Verheul, Elisa Giovannetti, Anna M.E. Bruynzeel, Annette A. van Zweeden, Maarten A J M Jacobs, Johanna W. Wilmink, Geert Kazemier, Hans J. van der Vliet, Martijn R. Meijerink

المساهمون: Cancer Center Amsterdam, Oncology, Radiotherapy, Medical oncology, Radiology and nuclear medicine, Radiation Oncology, Medical oncology laboratory, Surgery, Gastroenterology and hepatology, CCA - Innovative therapy

المصدر: van Zweeden, A A, van der Vliet, H J, Wilmink, J W, Meijerink, M R, Meijer, O W M, Bruynzeel, A M E, van Tienhoven, G, Giovannetti, E, Kazemier, G, Jacobs, M A J M & Verheul, H M W 2015, ' Phase I Clinical Trial to Determine the Feasibility and Maximum Tolerated Dose of Panitumumab to Standard Gemcitabine-Based Chemoradiation in Locally Advanced Pancreatic Cancer ', Clinical Cancer Research, vol. 21, no. 20, pp. 4569-4575 . https://doi.org/10.1158/1078-0432.CCR-14-3364Test
Clinical cancer research, 21(20), 4569-4575. American Association for Cancer Research Inc.
Clinical Cancer Research, 21(20), 4569-4575. American Association for Cancer Research Inc.

مصطلحات موضوعية: Male, Oncology, Radiation-Sensitizing Agents, Cancer Research, medicine.medical_specialty, Maximum Tolerated Dose, Combination therapy, medicine.medical_treatment, Phases of clinical research, Antineoplastic Agents, Deoxycytidine, Disease-Free Survival, Internal medicine, medicine, Humans, Panitumumab, Progression-free survival, Aged, Performance status, business.industry, Antibodies, Monoclonal, Chemoradiotherapy, Middle Aged, Combined Modality Therapy, Gemcitabine, ErbB Receptors, Pancreatic Neoplasms, Radiation therapy, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af044d3aa10a3aa41b4670af9233d5aTest
https://research.vumc.nl/en/publications/d841b4b3-1d46-4e67-931c-ea9631b374d0Test

المؤلفون: Richard J. Honeywell, Godefridus J. Peters, Elisa Giovannetti, Pieter E. Postmus, Otto Bekers, Harry J.M. Groen, Frederik B. Thunnissen, Daniëlle A M Heideman, Egbert F. Smit, Joline S.W. Lind, Anne-Marie C. Dingemans, Robert-Jan van Suylen

المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Pathologie, MUMC+: DA CDL Algemeen (9), RS: NUTRIM - R4 - Gene-environment interaction, Pulmonary medicine, Pathology, Medical oncology laboratory, CCA - Innovative therapy

المصدر: Clinical Cancer Research, 16(11), 3078-3087. AMER ASSOC CANCER RESEARCH
Lind, J S W, Dingemans, A M C, Groen, H J M, Thunnissen, F B J M, Bekers, O, Heideman, D A M, Honeywell, R J, Giovannetti, E, Peters, G J, Postmus, P E, van Suylen, R J & Smit, E F 2010, ' A Multicenter Phase II Study of Erlotinib and Sorafenib in Chemotherapy-Naive Patients with Advanced Non-Small Cell Lung Cancer ', Clinical Cancer Research, vol. 16, no. 11, pp. 3078-3087 . https://doi.org/10.1158/1078-0432.CCR-09-3033Test
Clinical Cancer Research, 16(11), 3078-3087. American Association for Cancer Research Inc.

مصطلحات موضوعية: Oncology, Male, Cancer Research, Lung Neoplasms, Pyridines, Phases of clinical research, Salvage therapy, TOXICITY, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Medicine, Epidermal growth factor receptor, RECURRENT, Erlotinib Hydrochloride, MUTATION, biology, Vascular Endothelial Growth Factors, Benzenesulfonates, Middle Aged, Sorafenib, ErbB Receptors, Female, Erlotinib, TYROSINE KINASE INHIBITOR, REFRACTORY SOLID TUMORS, BAY-43-9006, medicine.drug, Adult, Niacinamide, medicine.medical_specialty, EGFR, Disease-Free Survival, Proto-Oncogene Proteins p21(ras), Internal medicine, Proto-Oncogene Proteins, Humans, Lung cancer, Adverse effect, COMBINATION, Protein Kinase Inhibitors, neoplasms, Aged, FOOT SKIN REACTION, business.industry, Phenylurea Compounds, medicine.disease, Surgery, respiratory tract diseases, biology.protein, Quinazolines, ras Proteins, business, GROWTH-FACTOR RECEPTOR

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17249590b34145d465dcbb2a0e2b2133Test
https://research.rug.nl/en/publications/baabafd2-1f3b-4d55-a8bb-8b8d957bf3f2Test

المؤلفون: I. Garassino, Jose A. Rodriguez, Giovanni Luca Ceresoli, Giuseppe Giaccone, Armando Santoro, Paolo Andrea Zucali, Paolo M. Comoglio, Elisa Giovannetti, Massimo Roncalli, Karijn Floor, Annarita Destro, Marielle Gallegos Ruiz, Marileila Varella-Garcia

المساهمون: Medical oncology laboratory, Medical oncology, CCA - Innovative therapy

المصدر: Ann Oncol
Annals of Oncology, 19(9), 1605-1612. Oxford University Press
Zucali, P A, Ruiz, M G, Giovannetti, E, Destro, A, Varella-Garcia, M, Floor, K, Ceresoli, G L, Rodriguez, J A, Garassino, I, Comoglio, P, Roncalli, M, Santoro, A & Giaccone, G 2008, ' Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors ', Annals of Oncology, vol. 19, no. 9, pp. 1605-1612 . https://doi.org/10.1093/annonc/mdn240Test

مصطلحات موضوعية: Male, Lung Neoplasms, Kaplan-Meier Estimate, medicine.disease_cause, Tyrosine-kinase inhibitor, Cohort Studies, chemistry.chemical_compound, Carcinoma, Non-Small-Cell Lung, In Situ Hybridization, Fluorescence, Biopsy, Needle, Gefitinib, Hematology, Middle Aged, Protein-Tyrosine Kinases, Immunohistochemistry, ErbB Receptors, Gene Expression Regulation, Neoplastic, Treatment Outcome, Oncology, Female, KRAS, Growth inhibition, medicine.drug, medicine.drug_class, Blotting, Western, medicine, Humans, Lung cancer, neoplasms, Protein Kinase Inhibitors, Aged, Neoplasm Staging, Probability, Proportional Hazards Models, business.industry, Cancer, medicine.disease, Survival Analysis, respiratory tract diseases, lung cancer, chemistry, Drug Resistance, Neoplasm, Multivariate Analysis, Mutation, Cancer research, Quinazolines, Drug Screening Assays, Antitumor, business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4970f6bb5f4cef2f3972f8facf3929Test
https://europepmc.org/articles/PMC7360138Test/

المؤلفون: Armando Santoro, Alfredo Falcone, Giuseppe Giaccone, Godefridus J. Peters, Jacobus A. Burgers, Elisa Giovannetti, Romano Danesi, Armida D'Incecco, Paolo Andrea Zucali, Carmelo Tibaldi, Filippo Cortesi, Egbert F. Smit

المساهمون: Medical oncology laboratory, Pulmonary medicine, CCA - Innovative therapy

المصدر: Web of Science
Molecular Cancer Therapeutics, 9(3), 581-593. American Association for Cancer Research Inc.
Giovannetti, E, Zucali, P A, Peters, G J, Cortesi, F, D'Incecco, A, Smit, E F, Falcone, A, Burgers, J A, Santoro, A, Danesi, R, Giaccone, G & Tibaldi, C 2010, ' Association of Polymorphisms in AKT1 and EGFR with Clinical Outcome and Toxicity in Non-Small Cell Lung Cancer Patients Treated with Gefitinib ', Molecular Cancer Therapeutics, vol. 9, no. 3, pp. 581-593 . https://doi.org/10.1158/1535-7163.MCT-09-0665Test
Università di Pisa-IRIS
Publons

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions, Population, Antineoplastic Agents, Pharmacology, Polymorphism, Single Nucleotide, Biomarkers, Pharmacological, Gefitinib, Internal medicine, Carcinoma, Non-Small-Cell Lung, Genotype, medicine, Humans, Epidermal growth factor receptor, Lung cancer, education, neoplasms, Survival analysis, Aged, Retrospective Studies, Aged, 80 and over, education.field_of_study, biology, business.industry, Middle Aged, medicine.disease, Prognosis, Survival Analysis, respiratory tract diseases, ErbB Receptors, Treatment Outcome, Drug Resistance, Neoplasm, biology.protein, Quinazolines, Biomarker (medicine), Female, business, Proto-Oncogene Proteins c-akt, Pharmacogenetics, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fc4b7b10a929beaed8b02a975360daTest
https://publons.com/wos-op/publon/27272248Test/

المؤلفون: Godefridus J. Peters, Laura Boldrini, Gabriella Fontanini, Romano Danesi, Enrico Vasile, Carmelo Tibaldi, Roberto Incensati, Elisa Giovannetti, I. Bernardini, Marielle I. Gallegos-Ruiz, Federico Cappuzzo

المساهمون: Medical oncology laboratory, CCA - Oncogenesis

المصدر: Journal of Thoracic Oncology, 6(2), 395-396. International Association for the Study of Lung Cancer
Tibaldi, C, Giovannetti, E, Vasile, E, Boldrini, L, Gallegos-Ruiz, M I, Bernardini, I, Incensati, R, Danesi, R, Cappuzzo, F, Peters, G J & Fontanini, G 2011, ' Inherited Germline T790M Mutation and Somatic Epidermal Growth Factor Receptor Mutations in Non-small Cell Lung Cancer Patients ', Journal of Thoracic Oncology, vol. 6, no. 2, pp. 395-396 . https://doi.org/10.1097/JTO.0b013e3182059a6fTest

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Male, Adenocarcinoma, genetics/pathology, Aged, Carcinoma, Non-Small-Cell Lung, genetics/pathology, Carcinoma, Squamous Cell, genetics/pathology, Female, Germ-Line Mutation, genetics, Humans, Lung Neoplasms, genetics/pathology, Male, Middle Aged, Neoplasm Staging, Pedigree, Prognosis, Receptor, Epidermal Growth Factor, genetics, Lung Neoplasms, medicine.disease_cause, T790M, Germline mutation, Gefitinib, Epidermal growth factor, Carcinoma, Non-Small-Cell Lung, Adenocarcinoma of the lung, medicine, Humans, Epidermal growth factor receptor, Lung cancer, Germ-Line Mutation, Aged, Neoplasm Staging, Mutation, biology, business.industry, Carcinoma, genetics/pathology, Middle Aged, medicine.disease, Prognosis, respiratory tract diseases, Pedigree, ErbB Receptors, Oncology, Cancer research, biology.protein, Carcinoma, Squamous Cell, Female, business, medicine.drug, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94dbbbdef8b32476b7c126827b73ec9Test