المؤلفون: Proietti, C., Salatino, M., Rosemblit, C., Carnevale, R., Pecci, A., Kornblihtt, A.R., Molinolo, A.A., Frahm, I., Charreau, E.H., Schillaci, R., Elizalde, P.V.

المصدر: Mol. Cell. Biol. 2005;25(12):4826-4840

مصطلحات موضوعية: 4 amino 7 tert butyl 5 (4 chlorophenyl)pyrazolo[3,4 d]pyrimidine, antigestagen, Janus kinase, Janus kinase 1, Janus kinase 2, medroxyprogesterone acetate, mifepristone, mutant protein, progesterone derivative, protein tyrosine kinase, STAT3 protein, steroid receptor, animal cell, animal experiment, animal model, animal tissue, article, breast adenocarcinoma, breast cancer, cancer cell, cancer model, cell growth, cell proliferation, controlled study, enzyme activity, enzyme inhibition, expression vector, female, gene induction, genetic transfection

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.12110/paper_02707306_v25_n12_p4826_ProiettiTest; http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_02707306_v25_n12_p4826_Proietti_oaiTest

الإتاحة: https://doi.org/20.500.12110/paper_02707306_v25_n12_p4826_ProiettiTest
https://hdl.handle.net/20.500.12110/paper_02707306_v25_n12_p4826_ProiettiTest
http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_02707306_v25_n12_p4826_Proietti_oaiTest

المؤلفون: Martínez-Revelles S., García-Redondo A.B., Avendaño M.S., Varona S., Palao T., Orriols M., Roque F.R., Fortuño A., Touyz R.M., Martínez-González J., Salaices M., Rodríguez C., Briones A.M.

المصدر: ANTIOXIDANTS & REDOX SIGNALING
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

مصطلحات موضوعية: mitogen activated protein kinase p38, spontaneously hypertensive rat, enzyme induction, hypertension, vascular remodeling, animal experiment, elastin, hydrogen peroxide, animal cell, angiotensin II, reactive oxygen metabolite, hemodynamics, Article, animal tissue, glycol, disorders of mitochondrial functions, reduced nicotinamide adenine dinucleotide phosphate oxidase, mitochondrial membrane potential, male, apocynin, ani, Lox protein, mouse, 4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole, oxidative stress, Young modulus, controlled study, rat, protein structure, protein expression, 3 aminopropionitrile, comparative study, mouse, viscoelasticity, nonhuman, adult, animal model, catalase, scleroprotein, blood pressure, enzyme activation, superoxide dismutase, enzyme activity, arterial stiffness, priority journal, vascular smooth muscle cell, oxygen, protein lysine 6 oxidase, signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e2da9347c780fe72686d93379a9eaa5cTest
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026512486&doi=10.1089/ars.2016.6642&partnerID=40&md5=a058b16a0d7f5be1791decc6c5044e3fTest

المؤلفون: Mukeshd Doble, Ponnurengam Malliappan Sivakumar

المصدر: Medicinal Chemistry. 4:110-115

مصطلحات موضوعية: Models, Molecular, Steric effects, Quantitative structure–activity relationship, Binding Sites, Cyclooxygenase 2 Inhibitors, biology, Chemistry, Stereochemistry, Hydrogen bond, Binding energy, Quantitative Structure-Activity Relationship, Active site, Hydrogen Bonding, Interaction energy, 1 (4 fluorophenyl) 2 [(4 methylsulfonyl)phenyl]cyclopentene, 4 [5 (4 bromophenyl) 3 trifluoromethyl 1h pyrazol 1 yl]benzenesulfonamide, 5 (4 fluorophenyl) 1 [(4 methylsulfonyl)phenyl] 3 trifluoromethylpyrazole, 5 bromo 2 (4 fluorophenyl) 3 (4 methylsulfonylphenyl)thiophene, celecoxib, cyclooxygenase 2, cyclooxygenase 2 inhibitor, l 768 277, n (2 cyclohexyloxy 4 nitrophenyl)methanesulfonamide, nimesulide, prostaglandin synthase inhibitor, rofecoxib, sc 58451, valdecoxib, binding affinity, binding site, blood brain barrier, computer model, computer prediction, drug penetration, drug protein binding, drug structure, enzyme activity, IC 50, mathematical computing, priority journal, quantitative analysis, structure activity relation, chemical structure, chemistry, human, hydrogen bond, protein binding, quantitative structure activity relation, solubility, Blood-Brain Barrier, Cyclooxygenase 2, Humans, Inhibitory Concentration 50, Protein Binding, Solubility, Drug Discovery, biology.protein, Molecule, HOMO/LUMO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee361189381f7e3d39df02cbddbe431bTest
https://doi.org/10.2174/157340608783789112Test

المؤلفون: John O. Trent, Jason Chesney, Sucheta Telang, Brian F. Clem, Umesh Goswami, Abdullah Yalcin, Sengodagounder Arumugam, Amy L. Clem

المساهمون: Uludağ Üniversitesi/Veterinerlik Fakültesi/Biyokimya Anabilim Dalı., Yalçın, Abdullah, ABI-4164-2020, A-5261-2016

المصدر: Oncogene

مصطلحات موضوعية: Cancer Research, Choline kinase, Unclassified drug, Mouse, Biochemistry & molecular biology, Signal transduction, Mitogen activated protein kinase, Steady state, Computational biology, Hela cells, chemistry.chemical_compound, Mice, 0302 clinical medicine, n (3,5 dimethylphenyl) 2 [[5 (4 ethylphenyl) 1h 1,2,4 triazol 3 yl]sulfanyl] acetamide, Computer model, Acetamides, Phosphatidic acid, Second messenger, Cancer inhibition, Enzyme activity, Phosphorylation, Mitogen-activated protein kinases, Cell proliferation, Phosphocholine, Priority journal, Phosphatidic-acid, 0303 health sciences, Extracellular signal-regulated MAP kinases, Genetics & heredity, Enzyme inhibitors, Molecular interaction, Enzyme inhibitor, 3. Good health, Cell biology, Biochemistry, Oncology, Protein conformation, 030220 oncology & carcinogenesis, Female, Models, molecular, Phosphatidylinositol 3-kinases, Choline Kinase, Phosphoethanolamine, N Acetylaspartic Acid, Xenograft model antitumor assays, Human, Prostate-cancer, Phosphorylcholine, Choline kinase alpha, Biology, Protein targeting, Article, 03 medical and health sciences, Protein kinase B, Genetics, Chemotherapy, Animals, Humans, Animal model, Animal experiment, Protein kinase A, Molecular Biology, Lung tumor, 030304 developmental biology, MAP kinase kinase kinase, Inhibitors, In silico, Phospholipase-D, Proto-oncogene proteins c-akt, Ras activation, Triazoles, Nonhuman, Raf-1, Actins, MAP kinase signaling system, Proto-oncogene proteins p21(ras), Phosphatidylcholine, Metabolism, chemistry, P-31, Human cell, Breast-cancer-cells, Protein expression, Cyclin-dependent kinase 9, Tumor xenograft, Cell membrane, Controlled study, Phosphatidylinositol 3 kinase, Growth-factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c80b6dd975991bdaafb743d0952b0Test
http://hdl.handle.net/11452/22749Test

المؤلفون: Asimaki, O., Sakellaridis, N., Mangoura, D.

المصدر: Epitheorese Klinikes Farmakologias kai Farmakokinetikes ; http://www.scopus.com/inward/record.url?eid=2-s2.0-34248206155&partnerID=40&md5=e1c65259168dc0adffa0afe1e04d42e6Test

مصطلحات موضوعية: Cannabinoid receptor agonists, CB1, Epidermal growth factor receptor, 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 4 (3 chloroanilino) 6,7 dimethoxyquinazoline, cannabinoid 1 receptor, cannabinoid 1 receptor agonist, cannabinoid receptor agonist, enhanced green fluorescent protein, methanandamide, mitogen activated protein kinase, protein kinase C, protein tyrosine kinase, unclassified drug, cancer cell culture, cell membrane, conference paper, controlled study, drug antagonism, drug mechanism, drug receptor binding, enzyme activation, enzyme activity, fluorescence analysis, human, human cell, immunocytochemistry, immunoprecipitation, protein expression, protein glycosylation

العلاقة: http://hdl.handle.net/11615/25959Test

الإتاحة: http://hdl.handle.net/11615/25959Test

المؤلفون: Zeinalipour-Loizidou, E., Nicolaou, Charalambos P., Nicolaïdes, Andrew N., Kostrikis, Leontios G.

المساهمون: Kostrikis, Leontios G. [0000-0002-5340-7109]

المصدر: Current HIV Research
Curr.HIV Res.

مصطلحات موضوعية: antivirus agent, l 870812, Human immunodeficiency virus 1, gs 9137, HIV Integrase, protein MAP30, indolicidin, life cycle, curcumin, gs 1937, virus replication, media_common, fz 41, antiretrovirus agent, computer aided design, quantitative structure activity relation, salicylhydrazide, clinical trial, highly active antiretroviral therapy, molecular mechanics, unclassified drug, enzyme activity, dicaffeoylquinic acid, enzyme structure, Structure and function, antiinfective agent, n (4 fluorobenzyl) 8 hydroxy 5 (tetrahydro 2h 1,2 thiazin 2 yl) 1,6 naphthyridine 7 carboxamide s,s dioxide, Infectious Diseases, DNA integration, Anti-Retroviral Agents, real time polymerase chain reaction, drug withdrawal, antiviral activity, Hiv 1 integrase, thalassiolin a, Computer-Aided Design, drug potency, virus DNA, l 870712, Drug, medicine.medical_specialty, drug design, media_common.quotation_subject, protein GAP31, review, l 900612, 1 [5 (4 fluorobenzyl) 2 furyl] 3 (1,2,4 triazol 3 yl) 1,3 propanedione, virus RNA, Computer-aided drug design, Acquired immunodeficiency syndrome (AIDS), HIV-1 integrase, Virology, unindexed drug, medicine, Humans, human, HIV Integrase Inhibitors, DNA binding, Intensive care medicine, thalassiolin C, thalassiolin B, suramin, v 165, nonhuman, cichoric acid, drug potentiation, indolicidin derivative, Inhibitors, Mechanism (biology), business.industry, integrase inhibitor, drug targeting, X ray crystallography, virus load, Human immunodeficiency virus 1 infection, protein K159, medicine.disease, zintevir, Informatics, Drug Design, Immunology, mercaptosalicylhydrazide, integrase, business, high throughput screening

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65378c1f3f2281741708f721842cf575Test
https://pubmed.ncbi.nlm.nih.gov/17627500Test

مصطلحات موضوعية: Cannabinoid 2 receptor, Unclassified drug, Macrophage, Cytokine production, Cannabinoid derivative, Δ9-tetrahydrocanabinoid acid, Cyclic AMP, Cannabidiol, Dronabinol, Enzyme activity, Cultured, Cell strain U937, Delta 9 tetrahydrocannabinoid acid, Immunopharmacology, Supernatant, 6 iodo 3 (4 methoxybenzoyl) 2 methyl 1 (2 morpholinoethyl)indole, Zilpaterol, Cannabis sativa, CB1, CB2, Long term exposure, Health, Protein induction, 4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n morpholino 1h pyrazole 3 carboxamide, Beta 2 adrenergic receptor stimulating agent, Drug, Drug mechanism, TNF-alpha, Receptor, Signal Transduction, Immunomodulating agent, Cells, Protein synthesis regulation, Lipopolysaccharide, 1 (2, Down regulation, Concentration response, Cell Line, Heating, Immunomodulation, Dose-Response Relationship, Phospholipase C, cAMP, Upregulation, mental disorders, PC-PLC, Humans, Immunologic Factors, Biomedical research, Δ9-tetrahydrocanabinoid, Cannabinoid, Analytical research, Cannabis, Inflammation, Tumor necrosis factor alpha, Plant Extracts, Tumor Necrosis Factor-alpha, organic chemicals, Macrophages, Macrophage Activation, Cannabinoid 1 receptor, Heat, Drug effect, Phosphatidylcholine, Metabolism, Human cell, Tetrahydrocannabinol, Cannabidiolic acid, Controlled study, Immunostimulation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___00893::b10c0347a9c7edac96026d7e5c69a1fbTest
http://resolver.tudelft.nl/uuid:56538900-09c2-4e2c-92f5-877c7dfc22b4Test

المؤلفون: A.P. van Meeteren-Kreikamp, Kitty C.M. Verhoeckx, Mei Wang, Richard J. Rodenburg, Henrie A. A. J. Korthout, Karl A. Ehlert, Jan van der Greef, Renger F. Witkamp

المساهمون: TNO Kwaliteit van Leven

المصدر: International Immunopharmacology 6 (2006) 4
International Immunopharmacology, 6, 656-65
International Immunopharmacology, 4, 6, 656-665
International Immunopharmacology, 6, 4, pp. 656-65
International Immunopharmacology, 6(4), 656-665

مصطلحات موضوعية: Hot Temperature, Cannabinoid receptor, medicine.medical_treatment, Pharmacology, Cytokine production, Cannabinoid derivative, Receptor, Cannabinoid, CB2, transcriptomics, Receptor, Cannabinoid, CB1, Δ9-tetrahydrocanabinoid acid, Cannabinoid receptor type 2, cytokine, Dronabinol, Enzyme activity, Cells, Cultured, Cell strain U937, 6 iodo 3 (4 methoxybenzoyl) 2 methyl 1 (2 morpholinoethyl)indole, Zilpaterol, Cannabis sativa, Nutritional Biology, Long term exposure, Health, Drug mechanism, Immunomodulating agent, Energy and redox metabolism [NCMLS 4], Immunology, kappa-b, Concentration response, Genomic disorders and inherited multi-system disorders [IGMD 3], Heating, cAMP, Upregulation, PC-PLC, Humans, Immunologic Factors, Tetrahydrocannabinol, Analytical research, VLAG, Dose-Response Relationship, Drug, Tumor necrosis factor alpha, Tumor Necrosis Factor-alpha, organic chemicals, Macrophages, Macrophage Activation, human alveolar macrophages, Immunopharmacology, Drug effect, Human cell, Cannabidiolic acid, Cannabidiol, Immunostimulation, Cannabinoid 2 receptor, Unclassified drug, Macrophage, 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n morpholino 1h pyrazole 3 carboxamide, cell-line, Cyclic AMP, Immunology and Allergy, Chemistry, Delta 9 tetrahydrocannabinoid acid, Supernatant, lipopolysaccharide, differentiation, Mitochondrial medicine [IGMD 8], Biochemistry, Protein induction, Beta 2 adrenergic receptor stimulating agent, medicine.drug, TNF-alpha, Signal Transduction, brain, phospholipase-c, Protein synthesis regulation, Lipopolysaccharide, Down regulation, Cell Line, Immunomodulation, Phospholipase C, mental disorders, medicine, Biomedical research, Δ9-tetrahydrocanabinoid, Cannabis, Inflammation, Plant Extracts, Cannabinoid 1 receptor, Heat, Phosphatidylcholine, Metabolism, Genetic defects of metabolism [UMCN 5.1], Type C Phospholipases, activation, Cannabinoid, Controlled study

وصف الملف: application/pdf; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2e1f278e070c86acdb07021b5c29a5Test
http://resolver.tudelft.nl/uuid:56538900-09c2-4e2c-92f5-877c7dfc22b4Test

المؤلفون: Adali Pecci, Alfredo A. Molinolo, Alberto R. Kornblihtt, Cinthia Rosemblit, Patricia V. Elizalde, Eduardo H. Charreau, Mariana Salatino, Cecilia J. Proietti, Romina P. Carnevale, Roxana Schillaci, Isabel Frahm

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Mol. Cell. Biol. 2005;25(12):4826-4840
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

مصطلحات موضوعية: mifepristone, Medroxyprogesterone 17-Acetate, Gene Expression, animal cell, cancer model, Mice, mutant protein, cell growth, STAT3, enzyme inhibition, transcription initiation, cancer cell, medroxyprogesterone acetate, Mice, Inbred BALB C, Janus kinase 2, biology, Janus kinase 1, article, breast adenocarcinoma, Patología, purl.org/becyt/ford/3.1 [https], Protein-Tyrosine Kinases, enzyme activity, gene induction, DNA-Binding Proteins, Medicina Básica, female, tumor growth, src-Family Kinases, priority journal, PROTEIN TYROSINE KINASES, protein protein interaction, Female, purl.org/becyt/ford/3 [https], Receptors, Progesterone, signal transduction, hormones, hormone substitutes, and hormone antagonists, Proto-oncogene tyrosine-protein kinase Src, hormonal regulation, STAT3 Transcription Factor, Transcriptional Activation, antigestagen, CIENCIAS MÉDICAS Y DE LA SALUD, Antineoplastic Agents, Hormonal, animal experiment, Inmunología, Active Transport, Cell Nucleus, Breast Neoplasms, Medroxyprogesterone Acetate, protein DNA binding, TRAMSCRIPTIONAL ACTIVATION, DNA-binding protein, animal tissue, PROTO ONCOGENE PROTEINS, 4 amino 7 tert butyl 5 (4 chlorophenyl)pyrazolo[3,4 d]pyrimidine, STAT3 protein, BREAST CANCER, Cell Line, Tumor, Proto-Oncogene Proteins, protein targeting, Animals, Humans, controlled study, expression vector, protein expression, Molecular Biology, mouse, oncogene src, nonhuman, animal model, protein tyrosine kinase, Epithelial Cells, steroid receptor, Cell Biology, Janus Kinase 1, DNA, Janus Kinase 2, Trans-Activation (Genetics), protein phosphorylation, progesterone derivative, cell proliferation, hormonal carcinogenesis, Cancer research, biology.protein, STAT protein, Trans-Activators, genetic transfection, Breast cancer cells, Progestins, Janus kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a526e5add5ee64eedc10d8232ffa91d5Test
http://mcb.asm.org/cgi/pmidlookup?view=long&pmid=15923602Test

مصطلحات موضوعية: antioxidant, interleukin 1beta, cyclooxygenase 2 inhibitor, alpha tocopherol, incubation time, Antioxidants, growth inhibition, prostaglandin synthase, nonsteroid antiinflammatory agent, cell growth, cancer cell, Omega-6, Omega-3, Unsaturated, celecoxib, drug effect, Fatty Acids, malonaldehyde, lipid peroxidation, indometacin, docosahexaenoic acid, enzyme activity, colon cancer, priority journal, cytotoxicity, lipids (amino acids, peptides, and proteins), ascorbic acid, hypothesis, Colorectal Neoplasms, HT29 Cells, signal transduction, Cell Division, linoleic acid, omega 6 fatty acid, review, antineoplastic activity, omega 3 fatty acid, Dinoprostone, colorectal carcinoma, arachidonic acid, drug mechanism, Humans, controlled study, Cyclooxygenase Inhibitors, human, Biology, Analytical research, fatty acid synthesis, prostaglandin E2, human cell, 17 icosapentaenoic acid, enzyme activation, acetylsalicylic acid, carbene, cell proliferation, Prostaglandin-Endoperoxide Synthases, Caco-2 Cells, 5 (4 fluorophenyl) 1 [(4 methylsulfonyl)phenyl] 3 trifluoromethylpyrazole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___00893::475a9da1628bf42496c80d0daaab489eTest
http://resolver.tudelft.nl/uuid:4fe736f1-2aab-4490-888c-bcbe47caf951Test