التفاصيل البيبلوغرافية
| العنوان: |
Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe. |
| المؤلفون: |
Benschop, Kimberley S. M., Broberg, Eeva K., Hodcroft, Emma, Schmitz, Dennis, Albert, Jan, Baicus, Anda, Bailly, Jean-Luc, Baldvinsdottir, Gudrun, Berginc, Natasa, Blomqvist, Soile, Böttcher, Sindy, Brytting, Mia, Bujaki, Erika, Cabrerizo, Maria, Celma, Cristina, Cinek, Ondrej, Claas, Eric C. J., Cremer, Jeroen, Dean, Jonathan, Dembinski, Jennifer L. |
| المصدر: |
Emerging Infectious Diseases; Jun2021, Vol. 27 Issue 6, p1616-1626, 11p |
| مصطلحات موضوعية: |
MOLECULAR epidemiology, ENTEROVIRUS diseases, EPIDEMIOLOGY, ECHO viruses, RESEARCH, SEQUENCE analysis, BIOLOGICAL evolution, ECHO virus diseases, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, GENOTYPES, RESEARCH funding |
| مصطلحات جغرافية: |
EUROPE |
| مستخلص: |
In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016-2018. Most E30 cases affected persons 0-4 years of age (29%) and 25-34 years of age (27%). Sequences were divided into 6 genetic clades (G1-G6). Most (53%) sequences belonged to G1, followed by G6 (23%), G2 (17%), G4 (4%), G3 (0.3%), and G5 (0.2%). Each clade encompassed unique individual recombinant forms; G1 and G4 displayed >2 unique recombinant forms. Rapid turnover of new clades and recombinant forms occurred over time. Clades G1 and G6 dominated in 2018, suggesting the E30 upsurge was caused by emergence of 2 distinct clades circulating in Europe. Investigation into the mechanisms behind the rapid turnover of E30 is crucial for clarifying the epidemiology and evolution of these enterovirus infections. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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