التفاصيل البيبلوغرافية
| العنوان: |
MnO 2 Nanospheres Assisted by Cysteine Combined with MnO 2 Nanosheets as a Fluorescence Resonance Energy Transfer System for “Switch-on” Detection of Glutathione |
| المؤلفون: |
Yan Li (23143), Libing Zhang (1481890), Zhen Zhang (86004), Yu Liu (6938), Jing Chen (4762), Jia Liu (41593), Peiyao Du (8849297), Huixia Guo (11060279), Xiaoquan Lu (1427404) |
| سنة النشر: |
1753 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Molecular Biology, Biotechnology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, FRET process, energy donors, GSH, Cys-MnO 2 nanospheres, Fluorescence Resonance Energy Trans., MnO 2 Nanosheets, platform, Glutathione Manganese dioxide nanos., energy acceptors, fluorescence resonance energy transfer, recognition units, MnO 2 Nanospheres Assisted, manganese dioxide nanospheres |
| الوصف: |
Manganese dioxide nanosheets combined with cysteine-assisted emitting manganese dioxide nanospheres (Cys-MnO 2 nanospheres) is fabricated for the first time as an “off–on” fluorescence detection platform for glutathione (GSH). In this sensing system, Cys-MnO 2 nanospheres served as energy donors, while MnO 2 nanosheets were used as both energy acceptors and recognition units. MnO 2 nanosheets can effectively quench the fluorescence of Cys-MnO 2 nanospheres through the fluorescence resonance energy transfer (FRET). The addition of GSH could reduce MnO 2 nanosheets into Mn 2+ , disrupting the FRET process and restoring the fluorescence of Cys-MnO 2 nanospheres. Under the optimum conditions, the “switch-on” platform we established has a wide response to GSH with a range of 5–50 μM and 150–800 μM, as well as a superior specificity. Importantly, all components of the sensor are nontoxic, biocompatible, easily prepared, and have a high utilization of raw materials. Moreover, the sensing system achieved satisfactory results in human serum, showing a tremendous potential in the field of biomedicine. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/journal_contribution/MnO_sub_2_sub_Nanospheres_Assisted_by_Cysteine_Combined_with_MnO_sub_2_sub_Nanosheets_as_a_Fluorescence_Resonance_Energy_Transfer_System_for_Switch-on_Detection_of_Glutathione/14893391Test |
| DOI: |
10.1021/acs.analchem.1c01787.s001 |
| الإتاحة: |
https://doi.org/10.1021/acs.analchem.1c01787.s001Test |
| حقوق: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.F2ADC21 |
| قاعدة البيانات: |
BASE |
