المؤلفون: Saikia, Mridusmita, Holter, Marlena, Donahue, Leanne, Lee, Isaac, Zheng, Qiaonan, Wise, Journey, Todero, Jenna, Phuong, Daryl, Garibay, Darline, Coch, Reilly, Sloop, Kyle, Garcia-Ocana, Adolfo, Danko, Charles, Cummings, Bethany

المصدر: JCI Insight. 6(3)

مصطلحات موضوعية: Diabetes, Endocrinology, Islet cells, Metabolism, Animals, Female, Gene Knockdown Techniques, Glucagon-Like Peptide-1 Receptor, Glucagon-Secreting Cells, Humans, Hypoglycemic Agents, In Vitro Techniques, Insulin-Secreting Cells, Liraglutide, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Proprotein Convertase 1, RNA-Seq, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4293r376Test

المؤلفون: Marta Zielińska, Anna Mokrowiecka, Wanda M. Krajewska, Ewa Małecka-Panas, Damian Jacenik, Jakub Fichna, Maciej Sałaga, Hubert Zatorski

المصدر: Pharmacological Reports

مصطلحات موضوعية: Adult, Blood Glucose, Male, Crohn’s disease, medicine.medical_specialty, endocrine system, Dipeptidyl Peptidase 4, Incretin, Inflammation, Carbohydrate metabolism, Glucagon, Inflammatory bowel disease, Incretins, Article, Proinflammatory cytokine, Mice, Young Adult, Crohn Disease, Glucagon-Like Peptide 1, Internal medicine, medicine, Animals, Humans, Colitis, Receptor, Pharmacology, Glucose metabolism, business.industry, digestive, oral, and skin physiology, General Medicine, Middle Aged, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, DPP IV, GLP-1, Endocrinology, Proprotein Convertase 1, Trinitrobenzenesulfonic Acid, Case-Control Studies, Female, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28543d12ae72c2baa6419237feccc875Test
https://pubmed.ncbi.nlm.nih.gov/34535873Test

المؤلفون: Johanne Le Beyec Le Bihan, Muriel Coupaye, Jean-Claude Carel, Karine Clément, Patrick Tounian, Christine Poitou, Sophie Courbage, Jean-Marc Lacorte, A. Karsenty, Nathalie Lecomte, Julie Lemale, Gianpaolo De Filippo, Béatrice Dubern, Jean-Michel Oppert, Véronique Pelloux, Caroline Storey

المساهمون: Service de gastro-entérologie [CHU Trousseau], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Nutrition et obésités: approches systémiques (nutriomics) (UMR-S 1269 INSERM - Sorbonne Université), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Service de nutrition [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Service de Biochimie Endocrinienne et Oncologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Robert Debré Paris, Hôpital Robert Debré, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Hôpital Louis Mourier - AP-HP [Colombes], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Gestionnaire, Hal Sorbonne Université, Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Service de Nutrition [CHU Pitié-Salpétrière], Institut E3M [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

المصدر: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2021, ⟨10.1210/clinem/dgab404⟩
Journal of Clinical Endocrinology and Metabolism, 2021, ⟨10.1210/clinem/dgab404⟩

مصطلحات موضوعية: 0301 basic medicine, Proband, Adult, Leptin, Male, medicine.medical_specialty, Heterozygote, Pro-Opiomelanocortin, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Clinical Biochemistry, 030209 endocrinology & metabolism, Context (language use), leptin-melanocortin pathway, Biochemistry, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, severe early-onset obesity, Internal medicine, medicine, Endocrine system, Humans, Age of Onset, Child, Genotyping, Genetic Association Studies, Retrospective Studies, 2. Zero hunger, business.industry, Biochemistry (medical), Homozygote, Genetic Variation, medicine.disease, Phenotype, Obesity, Obesity, Morbid, [SDV] Life Sciences [q-bio], 030104 developmental biology, Proprotein Convertase 1, Receptors, Leptin, Female, business, Body mass index, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed3bc9ad643e77fb64e7d8036e68d4fTest
https://pubmed.ncbi.nlm.nih.gov/34097736Test

المؤلفون: Marianne Böni-Schnetzler, Marc Y. Donath, Daniel Konrad, Céline I. Laesser, Fabrizio C. Lucchini, Stephan Wueest, Marcela Borsigova, Werner Müller, Flurin Item

المصدر: Diabetes. 67:36-45

مصطلحات موضوعية: Leptin, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Proprotein convertase 1, Biology, Eating, Mice, 03 medical and health sciences, Insulin resistance, Glucagon-Like Peptide 1, Internal medicine, Adipocytes, Cytokine Receptor gp130, Internal Medicine, medicine, Animals, Interleukin 6, Mice, Knockout, Glucose tolerance test, medicine.diagnostic_test, Interleukin-6, Reverse Transcriptase Polymerase Chain Reaction, Insulin, digestive, oral, and skin physiology, Glucose Tolerance Test, Glycoprotein 130, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Proprotein Convertase 1, Knockout mouse, biology.protein, Cytokines, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c1bbf6b11bf029e775703e4e5241acTest
https://doi.org/10.2337/db17-0637Test

المؤلفون: E. Nazli Gonc, Nurgun Kandemir, Alev Ozon, Ayfer Alikasifoglu

المساهمون: Çocuk Sağlığı ve Hastalıkları

المصدر: Journal of Clinical Research in Pediatric Endocrinology

مصطلحات موضوعية: medicine.medical_specialty, Diabetic ketoacidosis, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Case Report, Proprotein convertase 1, Endocrine System Diseases, Diabetic Ketoacidosis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Diabetes mellitus, medicine, Humans, Obesity, treatment, Human Growth Hormone, business.industry, Insulin, Dietary management, Proprotein convertase 1/3 deficiency, medicine.disease, Proprotein Convertase 1, diabetes insipidus, diabetes mellitus, Pediatrics, Perinatology and Child Health, Female, 030211 gastroenterology & hepatology, business, 030217 neurology & neurosurgery, Follow-Up Studies, Rare disease, Hormone

وصف الملف: text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57176fab1480b214403de55ead55a0cTest
https://doi.org/10.4274/jcrpe.3986Test

المؤلفون: Austin J. Taylor, Yi-Chun Chen, C. Bruce Verchere

المصدر: Diabetes, Obesity and Metabolism. 20:64-76

مصطلحات موضوعية: 0301 basic medicine, endocrine system, endocrine system diseases, Amyloid, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Prohormone, Prohormone convertase, Enteroendocrine cell, Mixed Function Oxygenases, Islets of Langerhans, 03 medical and health sciences, Endocrinology, Insulin-Secreting Cells, Internal Medicine, medicine, Humans, Insulin, Proinsulin, geography, geography.geographical_feature_category, business.industry, Carboxypeptidase H, Proglucagon, Islet, Cell biology, Proprotein Convertase 2, 030104 developmental biology, Proprotein Convertase 1, Glucagon-Secreting Cells, Amidine-Lyases, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca561a9eb16f74f222230e91cce4eb3Test
https://doi.org/10.1111/dom.13401Test

المؤلفون: Iris Lindberg, Manita Shakya

المصدر: Endocr Rev

مصطلحات موضوعية: 0301 basic medicine, animal structures, Endocrinology, Diabetes and Metabolism, Mutant, Proprotein convertase 1, Review, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Human disease, Animals, Humans, Furin, Proprotein Convertase 5, biology, fungi, Proprotein convertase, Cell biology, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Proprotein Convertases, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5569c855498eb2084d38125b630ea5Test
https://pubmed.ncbi.nlm.nih.gov/33382413Test

المؤلفون: Guo Zhang, Ping Wang, Zhuo Chen, Dongsheng Cai, Yunliang Guan, Juxue Li, Susu Pan, Lihong Yan, Juan Li, Qing Shen, Yi Zhang, Faming Zhao, Xin Zhang

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, medicine.medical_specialty, endocrine system, Hypothalamus, Diet, High-Fat, Synaptotagmin 1, Mice, Synaptotagmins, Proopiomelanocortin, Internal medicine, medicine, Animals, Genetic Predisposition to Disease, Obesity, Protein kinase C, Mice, Knockout, Neurons, Multidisciplinary, biology, Activator (genetics), Biological Sciences, medicine.disease, Endocrinology, Proprotein Convertase 2, Gene Expression Regulation, Proprotein Convertase 1, biology.protein, Dyslipidemia, Intracellular, hormones, hormone substitutes, and hormone antagonists, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ac22761aa3d509fc4255214ab04a11Test
https://pubmed.ncbi.nlm.nih.gov/32747560Test

المؤلفون: Yaron Tomer, Angela Lombardi

المصدر: Journal of Autoimmunity. 80:48-55

مصطلحات موضوعية: X-Box Binding Protein 1, 0301 basic medicine, endocrine system, medicine.medical_specialty, medicine.medical_treatment, Immunology, Proprotein convertase 2, Apoptosis, Proprotein convertase 1, Article, Taurochenodeoxycholic Acid, 03 medical and health sciences, Downregulation and upregulation, Insulin-Secreting Cells, Internal medicine, medicine, Humans, Insulin, Immunology and Allergy, Cells, Cultured, Proinsulin, biology, Endoplasmic reticulum, Interferon-alpha, Endoplasmic Reticulum Stress, Phenylbutyrates, Diabetes Mellitus, Type 1, Proprotein Convertase 2, 030104 developmental biology, Endocrinology, Proprotein Convertase 1, Unfolded protein response, biology.protein, Cytokines, Binding immunoglobulin protein, Transcription Factor CHOP

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6789f874857b15982297d1b89ee240Test
https://doi.org/10.1016/j.jaut.2017.02.002Test

المؤلفون: Li Chen, Jia Song, Danyang Li, Huiqing Hu, Chen Cui, Nan Zang, Xinghong Guo, Qin He, Xinguo Hou, Xiaojie Wang, Chuan Wang, Fei Yan, Kai Liang, Xiangzhi Li

المصدر: Molecular and Cellular Endocrinology. 537:111425

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Population, Prohormone convertase, Apoptosis, Biochemistry, Glucagon, Cell Line, Diabetes Mellitus, Experimental, Histones, Endocrinology, In vivo, Internal medicine, Glucose Intolerance, medicine, Animals, Gene Regulatory Networks, Obesity, education, Molecular Biology, Histone Acetyltransferases, geography, education.field_of_study, geography.geographical_feature_category, Chemistry, Lysine, Insulin, fungi, Wild type, Acetylation, Islet, Salicylates, Diet, Mice, Inbred C57BL, Diabetes Mellitus, Type 2, Proprotein Convertase 1, Glucagon-Secreting Cells, Chromatin immunoprecipitation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b72eec3ffaa43bcb10cfd047e5a761Test
https://doi.org/10.1016/j.mce.2021.111425Test