المؤلفون: Anne U. Jackson, Francis S. Collins, Romy Kursawe, Ryan P. Welch, Michael L. Stitzel, Brooke N. Wolford, Michael R. Erdos, Michael Boehnke, Arushi Varshney, Ying Wu, Martin L. Buchkovich, Swarooparani Vadlamudi, Stephen C. J. Parker, Laura J. Scott, Karen L. Mohlke, Grace J. Kwon, Maren E Cannon, Markku Laakso, Tamara S. Roman, Johanna Kuusisto, Mario A. Morken

المصدر: Diabetes. 66:2521-2530

مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Pancreatic islets, Insulin, medicine.medical_treatment, Adenylate kinase, Type 2 diabetes, Biology, medicine.disease, Cyclase, 3. Good health, 03 medical and health sciences, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Internal medicine, Internal Medicine, medicine, Allele, Enhancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::aac244289bfb99d691b831b74b215ef7Test
https://doi.org/10.2337/db17-0464Test

المؤلفون: J. Graessler, Ulf Smith, Marie-France Hivert, Antigone S. Dimas, Joshua W. Knowles, Stéphane Cauchi, Karen L. Mohlke, Michael Boehnke, David Meyre, Nicholas J. Wareham, Ci Song, Denis Rybin, Erik Ingelsson, Mario A. Morken, Anne U. Jackson, Michael R. Erdos, Peter Kovacs, Fahim Abbasi, Claudia Langenberg, Ke Hao, Andreas Pfeiffer, Thomas Quertemous, Lars Lind, Stefan R. Bornstein, Suzannah Bumpstead, Alena Stančáková, Lori L. Bonnycastle, Michael Stumvoll, Oluf Pedersen, Themistocles L. Assimes, Inês Barroso, Andrea Benazzo, Richard M. Watanabe, Magic Investigators, Josée Dupuis, Inga Prokopenko, Heather M. Stringham, Felicity Payne, Markku Laakso, Antje Fischer-Rosinsky, Francis S. Collins, Mark Walker, James B. Meigs, Torben Hansen, Peter Schwarz, Xia Yang, Yvonne Böttcher, Hans-Ulrich Häring, Anke Tönjes, Narisu Narisu, Cécile Lecoeur, Jaakko Tuomilehto, Reedik Mägi, Joachim Spranger, Amy J. Swift, Johanna Kuusisto, Jose C. Florez, Niels Grarup, Philippe Froguel, Vasiliki Lagou, Peter S. Chines, Mark I. McCarthy, Adam Barker, Trine Welløv Boesgaard, Richard N. Bergman

المصدر: Diabetes 63, 2158-2171 (2013)
Diabetes
Diabetes, vol 63, iss 6
Dimas, A S, Lagou, V, Barker, A, Knowles, J W, Magi, R, Hivert, M F, Benazzo, A, Rybin, D, Jackson, A U, Stringham, H M, Song, C, Fischer-Rosinsky, A, Boesgaard, T W, Grarup, N, Abbasi, F A, Assimes, T L, Hao, K, Yang, X, Lecoeur, C, Barroso, I, Bonnycastle, L L, Bottcher, Y, Bumpstead, S, Chines, P S, Erdos, M R, Graessler, J, Kovacs, P, Morken, M A, Narisu, N, Payne, F, Stancakova, A, Swift, A J, Tonjes, A, Bornstein, S R, Cauchi, S, Froguel, P, Meyre, D, Schwarz, P E H, Haring, H U, Smith, U, Boehnke, M, Bergman, R N, Collins, F S, Mohlke, K L, Tuomilehto, J, Quertemous, T, Lind, L, Hansen, T, Pedersen, O, Walker, M, Pfeiffer, A F H, Spranger, J, Stumvoll, M, Meigs, J B, Wareham, N J, Kuusisto, J, Laakso, M, Langenberg, C, Dupuis, J, Watanabe, R M, Florez, J C, Ingelsson, E, McCarthy, M I, Prokopenko, I & Investigators, M 2014, ' Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity ', Diabetes, vol. 63, no. 6, pp. 2158-2171 . https://doi.org/10.2337/db13-0949Test

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Insulin Resistance/genetics, Type 2 diabetes, Medical and Health Sciences, Endocrinology, 0302 clinical medicine, Gene Frequency, Risk Factors, Insulin-Secreting Cells, Insulin Secretion, 2.1 Biological and endogenous factors, Cluster Analysis, Insulin, Aetiology, 2. Zero hunger, Genetics, 0303 health sciences, SLC30A8, Medicine (all), Diabetes, Single Nucleotide, Diabetes and Metabolism, Diabetes Mellitus, Type 2/genetics, Female, Type 2, Insulin processing, medicine.medical_specialty, Insulin/metabolism, Quantitative Trait Loci, Socio-culturale, 030209 endocrinology & metabolism, Biology, Autoimmune Disease, Polymorphism, Single Nucleotide, MAGIC Investigators, Endocrinology & Metabolism, 03 medical and health sciences, Insulin-Secreting Cells/metabolism, Insulin resistance, Clinical Research, Alleles, Diabetes Mellitus, Type 2, Genetic Variation, Genome-Wide Association Study, Humans, Insulin Resistance, Transcription Factors, Genetic Predisposition to Disease, Internal Medicine, Diabetes mellitus, Internal medicine, Genetic model, Diabetes Mellitus, medicine, Transcription Factors/metabolism, Polymorphism, Metabolic and endocrine, 030304 developmental biology, Glycemic, Prevention, medicine.disease, biology.protein, Quantitative Trait Loci/genetics, TCF7L2

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec76408386665bb3ac65c80f7efd345Test
https://doi.org/10.2337/db13-0949Test

المؤلفون: Lori L. Bonnycastle, Henna Cederberg, Alena Stančáková, Jussi Paananen, Pasi Soininen, Mika Ala-Korpela, Francis S. Collins, Niyas K. Saleem, Jussi Pihlajamäki, Jagadish Vangipurapu, Antti J. Kangas, Michael Boehnke, Yuvaraj Mahendran, Päivi Pajukanta, Karen L. Mohlke, Mete Civelek, Johanna Kuusisto, Mario A. Morken, Markku Laakso, Aldons J. Lusis

المصدر: Diabetes

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Population, Adipose tissue, 030209 endocrinology & metabolism, Ketone Bodies, Type 2 diabetes, Biology, Polymorphism, Single Nucleotide, White People, Acetoacetates, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Predictive Value of Tests, Risk Factors, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, education, Finland, Original Research, 030304 developmental biology, Metabolic Syndrome, 0303 health sciences, education.field_of_study, Glucose tolerance test, 3-Hydroxybutyric Acid, medicine.diagnostic_test, Genetics/Genomes/Proteomics/Metabolomics, Fasting, Glucose Tolerance Test, Middle Aged, medicine.disease, 3. Good health, Endocrinology, Diabetes Mellitus, Type 2, Area Under Curve, Hyperglycemia, Ketone bodies, Metabolic syndrome, Biomarkers, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e1c59be6633575f8252cac23cf204fTest
https://doi.org/10.2337/db12-1363Test

المؤلفون: Amanda J. Bennett, Lori L. Bonnycastle, Inês Barroso, Gudmar Thorleifsson, Charlotta Pisinger, Timothy M. Frayling, Laura J. Scott, Christian Herder, Mark Walker, Markku Laakso, Laura Pascoe, Beverley M. Shields, Thomas Sparsø, Ele Ferrannini, John R. B. Perry, Torsten Lauritzen, Felicity Payne, Thomas Illig, Michael N. Weedon, Beatrice Knight, Luigi Ferrucci, Giuseppe Paolisso, Claudia Langenberg, Andrew D. Morris, Torben Hansen, Ewan R. Pearson, Oluf Pedersen, Annelli Sandbæk, Peter Schwarz, Mario A. Morken, Colin N. A. Palmer, Peter Nilsson, Marcello Maggio, Narisu Narisu, Katharine R. Owen, Stefan R. Bornstein, Michael Boehnke, Mike Sampson, Leif Groop, Marjo-Riitta Järvelin, Aimo Ruokonen, Andrew T. Hattersley, Valgerdur Steinthorsdottir, Unnur Thorsteinsdottir, Ele Zeggini Magic, Mark I. McCarthy, Cecilia M. Lindgren, Christopher J. Groves, Elizabeth H. Young, Johanna Kuusisto, Harald Grallert, Valeriya Lyssenko, Anette P. Gjesing, Malin Neptin, Anne U. Jackson, Kari Stefansson, Nicholas J. Wareham, Heather M. Stringham

المساهمون: Perry, Jr, Weedon, Mn, Langenberg, C, Jackson, Au, Lyssenko, V, Sparsø, T, Thorleifsson, G, Grallert, H, Ferrucci, L, Maggio, M, Paolisso, Giuseppe, Walker, M, Palmer, Cn, Payne, F, Young, E, Herder, C, Narisu, N, Morken, Ma, Bonnycastle, Ll, Owen, Kr, Shields, B, Knight, B, Bennett, A, Groves, Cj, Ruokonen, A, Jarvelin, Mr, Pearson, E, Pascoe, L, Ferrannini, E, Bornstein, Sr, Stringham, Hm, Scott, Lj, Kuusisto, J, Nilsson, P, Neptin, M, Gjesing, Ap, Pisinger, C, Lauritzen, T, Sandbaek, A, Sampson, M, Zeggini, Me, Lindgren, Cm, Steinthorsdottir, V, Thorsteinsdottir, U, Hansen, T, Schwarz, P, Illig, T, Laakso, M, Stefansson, K, Morris, Ad, Groop, L, Pedersen, O, Boehnke, M, Barroso, I, Wareham, Nj, Hattersley, At, Mccarthy, Mi, Frayling, Tm

المصدر: Perry, J R B, Weedon, M N, Langenberg, C, Jackson, A U, Lyssenko, V, Sparsø, T, Thorleifsson, G, Grallert, H, Ferrucci, L, Maggio, M, Paolisso, G, Walker, M, Palmer, C N A, Payne, F, Young, E, Herder, C, Narisu, N, Morken, M A, Bonnycastle, L L, Owen, K R, Shields, B, Knight, B, Bennett, A, Groves, C J, Ruokonen, A, Jarvelin, M R, Pearson, E, Pascoe, L, Ferrannini, E, Bornstein, S R, Stringham, H M, Scott, L J, Kuusisto, J, Nilsson, P, Neptin, M, Gjesing, A P, Pisinger, C, Lauritzen, T, Sandbaek, A, Sampson, M, Zeggini, E, Lindgren, C M, Steinthorsdottir, V, Thorsteinsdottir, U, Hansen, T, Schwarz, P, Illig, T, Laakso, M, Stefansson, K, Morris, A D, Groop, L, Pedersen, O, Boehnke, M, Barroso, I, Wareham, N J, Hattersley, A T, McCarthy, M I & Frayling, T M 2010, ' Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes ', Human Molecular Genetics, vol. 19, no. 3, pp. 535-44 . https://doi.org/10.1093/hmg/ddp522Test
Hum. Mol. Genet. 19, 535-544 (2010)
Human Molecular Genetics
Perry, J R B, Weedon, M N, Langenberg, C, Jackson, A U, Lyssenko, V, Sparsø, T, Thorleifsson, G, Grallert, H, Ferrucci, L, Maggio, M, Paolisso, G, Walker, M, Palmer, C N A, Payne, F, Young, E, Herder, C, Narisu, N, Morken, M A, Bonnycastle, L L, Owen, K R, Shields, B, Knight, B, Bennett, A, Groves, C J, Ruokonen, A, Jarvelin, M R, Pearson, E, Pascoe, L, Ferrannini, E, Bornstein, S R, Stringham, H M, Scott, L J, Kuusisto, J, Nilsson, P, Neptin, M, Gjesing, A P, Pisinger, C, Lauritzen, T, Sandbaek, A, Sampson, M, Zeggini, E, Lindgren, C M, Steinthorsdottir, V, Thorsteinsdottir, U, Hansen, T, Schwarz, P, Illig, T, Laakso, M, Stefansson, K, Morris, A D & MAGIC 2010, ' Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes ', Human Molecular Genetics, vol. 19, no. 3, pp. 535-44 . https://doi.org/10.1093/hmg/ddp522Test
Human Molecular Genetics; Vol 19

مصطلحات موضوعية: Male, AUGSBURG CASE-COHORT, Genome-wide association study, Type 2 diabetes, 0302 clinical medicine, Sex hormone-binding globulin, Risk Factors, Sex Hormone-Binding Globulin, polycyclic compounds, Gonadal Steroid Hormones, 11 Medical and Health Sciences, Genetics (clinical), reproductive and urinary physiology, Genetics & Heredity, 0303 health sciences, biology, INSULIN SENSITIVITY, Association Studies Articles, General Medicine, Middle Aged, PROSTATE-CANCER, 3. Good health, POSTMENOPAUSAL WOMEN, MENDELIAN RANDOMIZATION, Female, TESTOSTERONE TREATMENT, Life Sciences & Biomedicine, hormones, hormone substitutes, and hormone antagonists, Adult, Biochemistry & Molecular Biology, medicine.medical_specialty, BODY-COMPOSITION, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, STEROID-HORMONES, Polymorphism, Single Nucleotide, 03 medical and health sciences, Diabetes mellitus, Internal medicine, Mendelian randomization, Genetics, medicine, Humans, GENOME-WIDE ASSOCIATION, Molecular Biology, 030304 developmental biology, Aged, Science & Technology, Case-control study, Odds ratio, 06 Biological Sciences, medicine.disease, MAGIC, SERUM CONCENTRATIONS, Endocrinology, Diabetes Mellitus, Type 2, Case-Control Studies, biology.protein

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https://ora.ox.ac.uk/objects/uuid:a806a09e-f734-4a9e-91c3-54be07dd26cdTest

المؤلفون: Michael Boehnke, Luigi Ferrucci, Aarti Surti, Jaakko Tuomilehto, Karen L. Mohlke, Candace Guiducci, Lee M. Kaplan, Rory Collins, Leena Peltonen, Qiong Yang, Cristen J. Willer, Francis S. Collins, Angelo Scuteri, Christopher J. O'Donnell, Edward G. Lakatta, Serkalem Demissie, Johanna Kuusisto, John C. Chambers, Amy J. Swift, Leif Groop, Markku Laakso, Gina M. Peloso, Sekar Kathiresan, Jouko Sundvall, G. Mark Lathrop, Gonçalo R. Abecasis, Benjamin F. Voight, Jose M. Ordovas, Veikko Salomaa, Eric E. Schadt, Robert Clarke, David Altshuler, David Schlessinger, Diana Zelenika, Pilar Galan, Serge Hercberg, Derrick A Bennett, Kari Kubalanza, Laura J. Scott, Kiran Musunuru, Kathryn L. Lunetta, Serena Sanna, Marju Orho-Melander, L. Adrienne Cupples, Toshiko Tanaka, Gabriel Crawford, Pierre Meneton, Josée Dupuis, Anne U. Jackson, Sarah Parish, Paul I.W. de Bakker, Yun Li, Olle Melander, Mario A. Morken, Manuela Uda, Heather M. Stringham, Lori L. Bonnycastle, Noël P. Burtt, Paul Scheet, Richard N. Bergman, Jaspal S. Kooner

مصطلحات موضوعية: Adult, Male, Multifactorial Inheritance, medicine.medical_specialty, Quantitative Trait Loci, Blood lipids, Genome-wide association study, 030204 cardiovascular system & hematology, Biology, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, chemistry.chemical_compound, Delta-5 Fatty Acid Desaturase, 0302 clinical medicine, Meta-Analysis as Topic, ANGPTL4, Internal medicine, Genetics, medicine, Humans, RNA, Messenger, Allele, Alleles, Triglycerides, Dyslipidemias, 030304 developmental biology, 0303 health sciences, Triglyceride, Cholesterol, Cholesterol, HDL, Reproducibility of Results, Cholesterol, LDL, Syndrome, Middle Aged, medicine.disease, 3. Good health, Phenotype, Endocrinology, Gene Expression Regulation, Liver, chemistry, Female, lipids (amino acids, peptides, and proteins), Dyslipidemia, Genome-Wide Association Study, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d725a804494fa65d0b3eab2f377b0f76Test
https://ora.ox.ac.uk/objects/uuid:4bf7b381-5e10-41d4-99a6-b6501ceded24Test

المؤلفون: John R. B. Perry, James B. Meigs, José Dupuis, Luigi Ferrucci, Johan G. Eriksson, Vilmundur Gudnason, Eric J.G. Sijbrands, Jeanette S. Andrews, Jonna L. Grimsby, Lawrence F. Bielak, Peter Kovacs, Panos Deloukas, Marijana Peričić, Johannes H. Smit, Ruth J. F. Loos, Gonneke Willemsen, Eric Boerwinkle, Ben A. Oostra, Manuel Serrano-Ríos, Alena Stančáková, Meena Kumari, Antti Jula, Michael Marmot, Caroline S. Fox, Simon Heath, Guo Li, Ola Hansson, Gerard Waeber, Anne U. Jackson, Nicholas L. Smith, Markku Laakso, George Dedoussis, Aarno Palotie, Sara M. Willems, John F. Peden, Elisabeth Widen, Caroline Hayward, Alan F. Wright, Claes Ladenvall, May E. Montasser, María Teresa Martínez-Larrad, Peter Vollenweider, Louis Pérusse, Tamara B. Harris, Wen Hong L. Kao, Danijela Budimir, Denis Rybin, David B. Savage, Michael A. Province, Alisa K. Manning, Bruna Gigante, Najaf Amin, Lenore J. Launer, Naveed Sattar, Lori L. Bonnycastle, Göran Hallmans, Jeffrey R. O'Connell, Stéphane Lobbens, Jacques S. Beckmann, Gemma Cadby, J. Wouter Jukema, Maria Dimitriou, Michael Stumvoll, Max Vikström, Rona J. Strawbridge, Hugh Watkins, Lyle J. Palmer, Johanna Kuusisto, Aimo Ruokonen, Hanieh Yaghootkar, Yan V. Sun, Inês Barroso, Amy J. Swift, Nancy L. Pedersen, Lars Lind, Mladen Boban, Nita G. Forouhi, Ken K. Ong, Ivana Kolcic, Anke Tönjes, Timothy M. Frayling, Paul W. Franks, Narisu Narisu, Karin Leander, Serge Hercberg, Diana Zelenika, Sharon L.R. Kardia, Min A. Jhun, Marjo-Riitta Järvelin, Stella Trompet, Jaakko Kaprio, Toshiko Tanaka, David S. Siscovick, Toby Johnson, Cornelia M. van Duijn, Veikko Salomaa, Jose C. Florez, James F. Wilson, Leena Peltonen, Pilar Galan, Robert Clarke, Andrew A. Hicks, Claudia Langenberg, Anders Hamsten, David Couper, Albert Hofman, Dawn M. Waterworth, John Blangero, James S. Pankow, Nabila Bouatia-Naji, Sirkka Keinänen-Kiukaanniemi, Mark I. McCarthy, Valeriya Lyssenko, Leif Groop, Brenda W.J.H. Penninx, Ching-Ti Liu, Anuj Goel, Marina Pehlić, Michael Boehnke, Mika Kivimäki, Maria Sabater-Lleal, Emil Rehnberg, Ingrid B. Borecki, Ozren Polasek, Eco J. C. de Geus, Peter P. Pramstaller, Igor Rudan, Richard M. Watanabe, Pierre Meneton, Iva Miljkovic, Vincent Mooser, G. Mark Lathrop, John Beilby, Laura J. Rasmussen-Torvik, Arturo Corbató-Anchuelo, Yvonne Böttcher, Richard N. Bergman, Daniel R. Barnes, Paul C. D. Johnson, Mustafa Atalay, Aroon D. Hingorani, Olga D. Carlson, Perttu Salo, Jacqueline C.M. Witteman, Udo Seedorf, Timo Saaristo, Jian'an Luan, Nicholas J. Wareham, Gudny Eiriksdottir, Matti Uusitupa, Yongmei Liu, Jaakko Tuomilehto, Yurii S. Aulchenko, Peter Schwarz, Robert A. Scott, Lina Zgaga, Joseph Hung, Reedik Mägi, Maria Grazia Franzosi, Eric J. Brunner, Claude Bouchard, Ian Ford, Francis S. Collins, Ulf de Faire, Benjamin F. Voight, Erik Ingelsson, Mario A. Morken, Stefania Bandinelli, Nicole L. Glazer, Dmitry Shungin, Lars Lannfelt, André G. Uitterlinden, Tatijana Zemunik, Markus Perola, Kenneth Rice, Veronique Vitart, Kerrin S. Small, Jouke-Jan Hottenga, Han Chen, Jerome I. Rotter, Philippe Froguel, Karen L. Mohlke, Marie-Claude Vohl, Dorret I. Boomsma, Harry Campbell, Peter S. Chines, Pau Navarro, Vasiliki Lagou, Albert V. Smith, Kathleen Stirrups, Josephine M. Egan, Alan R. Shuldiner, Katri Räikkönen, Inga Prokopenko, Ping An, Rainer Rauramaa, Beverley Balkau, Thor Aspelund, Eleanor Wheeler, Mariza de Andrade, Richa Saxena, Jari Lahti, Cécile Lecoeur, Timo A. Lakka, Jennie Hui, Michael R. Erdos, Stavroula Kanoni, Kirsten Ohm Kyvik, Bengt Sennblad, Sarah H. Wild, Patricia A. Peyser, Patrik K. E. Magnusson, Claire Bellis, Elodie Eury, Jaana Lindström

المساهمون: Boston University [Boston] (BU), Broad Institute of Harvard and MIT, Partenaires INRAE, Massachusetts General Hospital, Massachusetts General Hospital [Boston], Department of Genetics [Boston], Harvard Medical School [Boston] (HMS), Department of Medicine, Université de Sherbrooke (UdeS), Addenbrooke's Hospital, Harvard Medical School [Boston] (HMS)-Beth Israel Deaconess Medical Center [Boston] (BIDMC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), Université Lille Nord de France (COMUE), Department of Epidemiology, University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System-Center for Social Epidemiology and Population Health, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford [Oxford], The Wellcome Trust Centre for Human Genetics [Oxford], The Netherlands Cancer Institute, Ontario Institute for Cancer Research, Mount Sinai Hospital [Toronto, Canada] (MSH), VU University Amsterdam, Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet [Stockholm], University of Michigan System, Queen Mary University of London (QMUL), The Wellcome Trust Sanger Institute [Cambridge], Lund University [Lund], Diabetes Centre, Lund University, University of Helsinki, Wake Forest School of Medicine, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, University of Maryland School of Medicine, University of Maryland System, University of Edinburgh, University of Exeter, Department of Twin Research and Genetic Epidemiology, King's College London, London, Northwestern University [Evanston], National Institute of Health and Welfare, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Lund University Diabetes Centre, Umeå University, National Institutes of Health, Centre for Medical Systems Biology, Netherlands Genomics Initiative, Washington University in Saint Louis (WUSTL), Department of Health Sciences Research, Mayo Clinic, Wake Forest University, Icelandic Heart Association, Heart Preventive Clinic and Research Institute, University of Iceland, Institute of Biomedicine, Physiology, University of Eastern Finland, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR S 1018, Université Paris-Sud - Paris 11 (UP11), Azienda Sanitaria Firenze, Department of Medical Genetics, Université de Lausanne (UNIL), Centre Hospitalier Universitaire Vaudois (CHUV), Queen Elizabeth II Medical Centre, Research Institute, University of Southern California (USC), University of Split, The University of Texas Health Science Center at Houston (UTHealth), Leipzig University, Pennington Biomedical Research Center, Department of Epidemiology & Public Health, University College of London [London] (UCL), San Carlos Clinical Hospital, University of North Carolina, Harokopio University, National Institute on Aging, Folkhälsan Research Centre, Vaasa Central Hospital, Unité de Recherche en Epidémiologie Nutritionnelle (UREN), Université Paris 13 (UP13)-Institut National de la Recherche Agronomique (INRA)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Psychiatry, EMGO - Lifestyle, overweight and diabetes, Epidemiology, Immunology, Erasmus School of Social and Behavioural Sciences, Clinical Genetics, Ophthalmology, Internal Medicine, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Multiple Tissue Human Expression Resource (MUTHER) Consortium, Ahmadi, K.R., Ainali, C., Barrett, A., Bataille, V., Bell, J.T., Buil, A., Deloukas, P., Dermitzakis, E.T., Dimas, A.S., Durbin, R., Glass, D., Grundberg, E., Hassanali, N., Hedman, Å.K., Ingle, C., Knowles, D., Krestyaninova, M., Lindgren, C.M., Lowe, C.E., McCarthy, M.I., Meduri, E., di Meglio, P., Min, J.L., Montgomery, S.B., Nestle, F.O., Nica, A.C., Nisbet, J., O'Rahilly, S., Parts, L., Potter, S., Sekowska, M., Shin, S.Y., Small, K.S., Soranzo, N., Spector, T.D., Surdulescu, G., Travers, M.E., Tsaprouni, L., Tsoka, S., Wilk, A., Yang, T.P., Zondervan, K.T., Voight, B.F., Scott, L.J., Steinthorsdottir, V., Morris, A.P., Dina, C., Welch, R.P., Zeggini, E., Huth, C., Aulchenko, Y.S., Thorleifsson, G., McCulloch, L.J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C.J., Raychaudhuri, S., McCarroll, S.A., Langenberg, C., Hofmann, O.M., Dupuis, J., Qi, L., Segrè, A.V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A.J., Blagieva, R., Boerwinkle, E., Bonnycastle, L.L., Boström, K.B., Bravenboer, B., Bumpstead, S., Burtt, N.P., Charpentier, G., Chines, P.S., Cornelis, M., Couper, D.J., Crawford, G., Doney, A.S., Elliott, K.S., Elliott, A.L., Erdos, M.R., Fox, C.S., Franklin, C.S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C.J., Guiducci, C., Hadjadj, S., Herder, C., Isomaa, B., Jackson, A.U., Johnson, P.R., Jørgensen, T., Kao, W.H., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M.A., Narisu, N., Nilsson, P., Owen, K.R., Payne, F., Perry, J.R., Petersen, A.K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N.W., Robertson, N.R., Rocheleau, G., Roden, M., Sampson, M.J., Saxena, R., Shields, B.M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H.M., Sun, Q., Swift, A.J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R.M., van Haeften, T.W., van Herpt, T., van Vliet-Ostaptchouk, J.V., Walters, G.B., Weedon, M.N., Wijmenga, C., Witteman, J., Bergman, R.N., Cauchi, S., Collins, F.S., Gloyn, A.L., Gyllensten, U., Hansen, T., Hide, W.A., Hitman, G.A., Hofman, A., Hunter, D.J., Hveem, K., Laakso, M., Mohlke, K.L., Morris, A.D., Palmer, C.N., Pramstaller, P.P., Rudan, I., Sijbrands, E., Stein, L.D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N.J., Watanabe, R.M., Abecasis, G.R., Boehm, B.O., Campbell, H., Daly, M.J., Hattersley, A.T., Hu, F.B., Meigs, J.B., Pankow, J.S., Pedersen, O., Wichmann, H.E., Barroso, I., Florez, J.C., Frayling, T.M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J.F., Illig, T., Froguel, P., van Duijn, C.M., Stefansson, K., Altshuler, D., Boehnke, M., Biological Psychology, EMGO+ - Lifestyle, Overweight and Diabetes, Vrije universiteit = Free university of Amsterdam [Amsterdam] (VU), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Sorbonne Paris Cité (USPC)-Université Paris 13 (UP13)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut National de la Recherche Agronomique (INRA)

المصدر: Nature Genetics, 44(6), 659-669. Nature Publishing Group
Nature Genetics
Nature Genetics, Nature Publishing Group, 2012, 44 (6), pp.659-671. ⟨10.1038/ng.2274⟩
Manning, A K, Hivert, M-F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C-T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J-J, Ingelsson, E, Jackson, A U, Johnson, T, Kanoni, S, Ladenvall, C, Lagou, V, Lahti, J, Lecoeur, C, Liu, Y, Martinez-Larrad, M T, Montasser, M E, Navarro, P, Perry, J R B, Rasmussen-Torvik, L J, Salo, P, Sattar, N, Shungin, D, Strawbridge, R J, Tanaka, T, van Duijn, C M, An, P, de Andrade, M, Andrews, J S, Aspelund, T, Atalay, M, Aulchenko, Y, Balkau, B, Bandinelli, S, Campbell, H, Hayward, C, Rudan, I, Vitart, V, Wild, S H, Wilson, J F & Wright, A F & Zgaga, L 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-U81 . https://doi.org/10.1038/ng.2274Test
Nature Genetics, 44(6), 659-U81. Nature Publishing Group
Nature Genetics; Vol 44
Nature genetics, vol. 44, no. 6, pp. 659-669
Manning, A K, Hivert, M F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J J, Ingelsson, E, Boomsma, D I, de Geus, E J C, Penninx, B W J H, Willemsen, G, Wilson, J F, Witteman, J C M, Wright, A F, Yaghootkar, H, Zelenika, D, Zemunik, T, Zgaga, L, Wareham, N J, McCarthy, M I, Barroso, I, Watanabe, R M, Florez, J C, Dupuis, J, Meigs, J B & Langenberg, C 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-669 . https://doi.org/10.1038/ng.2274Test
Manning, A K, Hivert, M-F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C-T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J-J, Ingelsson, E, Jackson, A U, Johnson, T, Kanoni, S, Ladenvall, C, Lagou, V, Lahti, J, Lecoeur, C, Liu, Y, Martinez-Larrad, M T, Montasser, M E, Navarro, P, Perry, J R B, Rasmussen-Torvik, L J, Salo, P, Sattar, N, Shungin, D, Strawbridge, R J, Tanaka, T, van Duijn, C M, An, P, de Andrade, M, Andrews, J S, Aspelund, T, Atalay, M, Aulchenko, Y, Balkau, B, Bandinelli, S, Beckmann, J S, Beilby, J P, Bellis, C, Bergman, R N, Blangero, J, Boban, M, Boehnke, M, Kyvik, K O & DIAGRAM Consortium 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-669 . https://doi.org/10.1038/ng.2274Test
Nature Genetics, 44(6), 659-U81

مصطلحات موضوعية: Blood Glucose, Netherlands Twin Register (NTR), medicine.medical_treatment, [SDV]Life Sciences [q-bio], LOCI, Genome-wide association study, Type 2 diabetes, SUSCEPTIBILITY, Body Mass Index, GLUCOSE, Blood Glucose/metabolism, Cholesterol, HDL/metabolism, Diabetes Mellitus, Type 2/genetics, Genome-Wide Association Study, Humans, Insulin/metabolism, Insulin Resistance/genetics, Polymorphism, Single Nucleotide, 0302 clinical medicine, Insulin, 2. Zero hunger, Genetics, 0303 health sciences, COMMON VARIANTS, 3. Good health, ENVIRONMENT INTERACTION, OBESITY, CORONARY-ARTERY-DISEASE, medicine.medical_specialty, 030209 endocrinology & metabolism, Accounting, Biology, Article, 03 medical and health sciences, Insulin resistance, SDG 3 - Good Health and Well-being, Internal medicine, Diabetes mellitus, medicine, 030304 developmental biology, Genetic association, Glycemic, loci, SNP, insulin, business.industry, Cholesterol, HDL, medicine.disease, Obesity, POLYMORPHISM, ASSOCIATION ANALYSIS, Endocrinology, Diabetes Mellitus, Type 2, TYPE-2 DIABETES RISK, Insulin Resistance, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690ec4f28111d0636e4eb653c35f7bc2Test
https://doi.org/10.1038/ng.2274Test

المؤلفون: Pasi Soininen, Markku Laakso, Michael Boehnke, Alena Stančáková, Niyas K. Saleem, Aldons J. Lusis, Mario A. Morken, Mika Ala-Korpela, Päivi Pajukanta, Henna Cederberg, Antti J. Kangas, Johanna Kuusisto, Lori L. Bonnycastle, Jussi Pihlajamäki, Jussi Paananen, Francis S. Collins, Mete Civelek

المصدر: Diabetes

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Internal medicine, Internal Medicine, medicine, Aromatic amino acids, Humans, Genetic Predisposition to Disease, Amino Acids, Finland, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Aged, Alanine, chemistry.chemical_classification, 0303 health sciences, Genetics/Genomes/Proteomics/Metabolomics, Middle Aged, medicine.disease, 3. Good health, Amino acid, Glutamine, Endocrinology, chemistry, Adipose Tissue, Diabetes Mellitus, Type 2, Gene Expression Regulation, Hyperglycemia, Metabolic syndrome, Leucine, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527233e0be12f87b130f3fe112c321caTest
http://europepmc.org/articles/PMC3379649Test

المؤلفون: Mika Ala-Korpela, Antti J. Kangas, Lori L. Bonnycastle, Johanna Kuusisto, Jussi Paananen, Francis S. Collins, Markku Laakso, Michael Boehnke, Mario A. Morken, Alena Stančáková, Anne U. Jackson, Pasi Soininen

المصدر: Diabetes

مصطلحات موضوعية: Fatty Acid Desaturases, Male, Very low-density lipoprotein, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Genotype, Endocrinology, Diabetes and Metabolism, Population, Cholesterol, VLDL, Single-nucleotide polymorphism, Type 2 diabetes, Biology, Lipoproteins, VLDL, Polymorphism, Single Nucleotide, White People, chemistry.chemical_compound, Delta-5 Fatty Acid Desaturase, Internal medicine, Internal Medicine, medicine, Genetics, Humans, Receptor, Notch2, Risk factor, education, Adaptor Proteins, Signal Transducing, education.field_of_study, Cholesterol, Middle Aged, medicine.disease, Lipoproteins, LDL, Endocrinology, chemistry, Diabetes Mellitus, Type 2, Lipoproteins, IDL, Hyperglycemia, lipids (amino acids, peptides, and proteins), Metabolic syndrome, Lipoproteins, HDL, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e6fb48e496803b617a6cca962e7a9dTest
http://europepmc.org/articles/PMC3292337Test

المؤلفون: Kenneth Rice, Amy J. Swift, Veronique Vitart, Lu Qi, Kaisa Silander, Olivier Le Bacquer, Laura Crisponi, David S. Siscovick, Bo Isomaa, Anne U. Jackson, Anke Tönjes, Richard N. Bergman, Rosa Maria Roccasecca, Luigi Ferrucci, Narisu Narisu, Kari Stefansson, Holly E. Syddall, Giuseppe Paolisso, Kim L. Ward, Paul Elliott, Scott M. Grundy, Paul Johnson, Jerome I. Rotter, Philippe Froguel, James B. Meigs, George Davey Smith, Andrew T. Hattersley, Leena Peltonen, Eric J.G. Sijbrands, Serena Sanna, María TeresaMartínez-Larrad, David Altshuler, Harald Grallert, Caroline S. Fox, Nita G. Forouhi, Dorret I. Boomsma, Harry Campbell, Jean Tichet, Angelo Scuteri, Aroon D. Hingorani, Daniel S. Pearson, Meena Kumari, Silvia Naitza, Shah Ebrahim, Manjinder S. Sandhu, Jose C. Florez, Cyrus Cooper, David M. Nathan, Joseph Hung, Fredrik Karpe, Ozren Polasek, Philip J. Barter, Ruth McPherson, Benjamin F. Voight, Wolfgang Rathmann, Abbas Dehghan, Udo Seedorf, Beverley M. Shields, Antti Jula, Pau Navarro, Josephine M. Egan, Rune R. Frants, Leif Groop, Gunnar Sigursson, Seppo Koskinen, Vincent Mooser, François Pattou, Jing Hua Zhao, Irene Pichler, John F. Peden, Göran Hallmans, Toshiko Tanaka, Ruth J. F. Loos, Peter Kovacs, Andrew D. Morris, Cécile Lecoeur, Jeffrey R. O'Connell, Massimo Mangino, Nicole Vogelzangs, Rhian Gwilliam, Gordon H. Williams, Carina Zabena, Naomi Hammond, Amélie Bonnefond, Björn Zethelius, Joachim Spranger, Nancy L. Pedersen, Christopher J. Groves, Nicholas J. Timpson, George Dedoussis, Veikko Salomaa, Peter Henneman, Andrew Walley, Serge Hercberg, Ian N. M. Day, Simon Heath, Matt Neville, Alex S. F. Doney, Robert Clarke, Olov Rolandsson, Panos Deloukas, Eric Boerwinkle, Y. AnteroKesaniemi, Mike Sampson, Gerard Waeber, Sven Bergmann, Ben A. Oostra, Manuel Serrano-Ríos, Mandy van Hoek, Christine Cavalcanti-Proença, Anna L. Gloyn, Ulla Sovio, Andrew P. Morris, Anneli Pouta, Amanda J. Bennett, Paul Scheet, Peter Schwarz, Jaakko Tuomilehto, Hugh Watkins, Johanna Kuusisto, Denis Rybin, Anna LiisaHartikainen, Maria GraziaFranzosi, Unnur Thorsteinsdottir, Rafn Benediktsson, Alan F. Wright, Colin N. Apalmer, Anuj Goel, Yavuz Ariyurek, Lars Lind, Robert Sladek, Stefan R. Bornstein, Reedik Mägi, Laila Simpson, Tim D. Spector, Paul W. Franks, Nicholas L. Smith, John R. B. Perry, Peter Vollenweider, Suzannah Bumpstead, Ruth E. Pakyz, Christa Meisinger, Alan R. Shuldiner, Josée Dupuis, Man Li, Eric J. Brunner, Francis S. Collins, Torben Hansen, James F. Wilson, Guangju Zhai, Igor Rudan, Nicole L. Glazer, Marco Orrù, Pierre Meneton, Knut Borch-Johnsen, Eleanor Wheeler, Gonçalo R. Abecasis, Mark I. McCarthy, Jouke JanHottenga, Inga Prokopenko, Ping An, Jérôme Delplanque, Albert Hofman, Andrew B. Singleton, Gabe Crawford, Thomas A. Buchanan, Avan Aihie Sayer, Richard M. Watanabe, David Schlessinger, A C Fedson, André G. Uitterlinden, Frank B. Hu, Jaqueline C. MWitteman, Dhiraj Varma, Ingrid B. Borecki, Sutapa Mukherjee, Murielle Bochud, Barbara Thorand, Christian Gieger, Lori L. Bonnycastle, Stephen J. Sharp, Markus Perola, Caroline Hayward, Kristin Ardlie, J. Graessler, Robert W. Mahley, Toby Johnson, Jian'an Luan, Joshua C. Randall, Cornelia M. van Duijn, Samuli Ripatti, Ko Willems van Dijk, Valgerdur Steinthorsdottir, Yurii S. Aulchenko, G. Mark Lathrop, Christian Dina, Eleftheria Zeggini, Cecilia M. Lindgren, Stavroula Kanoni, Timothy M. Frayling, Dawn M. Waterworth, Marika Kaakinen, Timo T. Valle, Diana Zelenika, Yii Der IdaChen, Angela Silveira, Nigel W. Rayner, Aimo Ruokonen, Yun Li, Cristian Pattaro, Annelli Sandbæk, Richa Saxena, Danielle Posthuma, Steven A. McCarroll, Niels Grarup, Samy Hadjadj, Pilar Galan, Xijing Han, Lyle J. Palmer, Ulf Gyllensten, Peter P. Pramstaller, Manuela Uda, Jarred B. McAteer, Brenda W.J.H. Penninx, Debbie A Lawlor, Torben Jørgensen, Beatrice Knight, Yvonne Böttcher, Claudia Langenberg, Nicole Soranzo, Ghislain Rocheleau, Erik Ingelsson, Mario A. Morken, Michael Roden, Felicity Payne, David R. Hillman, Michael Marmot, Karen L. Mohlke, Heather M. Stringham, Bruce M. Psaty, Gudmar Thorleifsson, Yoav Ben-Shlomo, Inês Barroso, W. H. Linda Kao, James S. Pankow, Valeriya Lyssenko, Nicholas J. Wareham, Tiinamaija Tuomi, Ann ChristineSyvänen, Braxton D. Mitchell, Alisa K. Manning, Mika Kivimäki, Peter Wagner, Praveen Sethupathy, G. BragiWalters, Jaakko Kaprio, Kijoung Song, Marjo Riitta-Järvelin, Michael A. Province, Andrew A. Hicks, Marilyn C. Cornelis, Sarah H. Wild, David Meyre, Guillaume Charpentier, Patrik K. E. Magnusson, David Melzer, Jennie Hui, Peter Shrader, Michael Stumvoll, Mark O. Goodarzi, Michael R. Erdos, Oluf Pedersen, Andreas Pfeiffer, Augustine Kong, Christian Herder, Laura J. Scott, John W. GYarnell, Kirsten Ohm Kyvik, Beverley Balkau, Antje Fischer-Rosinsky, Gonneke Willemsen, Thomas Illig, Neelam Hassanali, Markku Laakso, Michael Boehnke, John Beilby, Christopher S. Franklin, Fernando Rivadeneira, M. Carola Zillikens, Michael N. Weedon, Antonio Cao, Mark E. Cooper, Simon C. Potter, Eco J. C. de Geus, H.-Erich Wichmann, Amanda F. Elliott, Lachlan J. McOin, Sophie Visvikis-Siest, Thomas Sparsø, Laura J. McCulloch, Taina K. Lajunen, Peter S. Chines, Nabila Bouatia-Naji

المساهمون: Medical Research Council (MRC), Biological Psychology, Functional Genomics, Neuroscience Campus Amsterdam - Anxiety & Depression, Neuroscience Campus Amsterdam - Attention & Cognition, EMGO+ - Mental Health, Ophthalmology, Epidemiology, Clinical Genetics, Dermatology, Internal Medicine, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, MAGIC investigators, Human genetics, Psychiatry, EMGO - Mental health, NCA - Attention & Cognition, NCA - Anxiety & Depression

المصدر: Nature Genetics
Dupuis, J, Langenberg, C, Prokopenko, I, Saxena, R, Soranzo, N, Jackson, A U, Wheeler, E, Glazer, N L, Bouatia-Naji, N, Gloyn, A L, Lindgren, C M, Mägi, R, Morris, A P, Randall, J, Johnson, T, Hottenga, J J, de Geus, E J C, Kaprio, J, Kyvik, K O, Pedersen, N L, Perola, M, Posthuma, D, Rivadeneira, F, Uitterlinden, A G, Willems van Dijk, K, van Hoek, M, Vogelzangs, N, Willemsen, G, Witteman, J C M, Zillikens, M C, Penninx, B W J H, Boomsma, D I, van Duijn, C M, Aulchenko, Y S, Waterworth, D, Vollenweider, P, Peltonen, L, Mooser, V, Abecasis, G R, Wareham, N J, Sladek, R, Froguel, P, Watanabe, R M, Meigs, J B, Groop, L C, Boehnke, M, McCarthy, M I, Florez, J C & Barroso, I 2010, ' New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk ', Nature Genetics, vol. 42, no. 2, pp. 105-116 . https://doi.org/10.1038/ng.520Test
Nature genetics
U32
Dupuis, J, Langenberg, C, Prokopenko, I, Saxena, R, Soranzo, N, Jackson, A U, Wheeler, E, Glazer, N L, Bouatia-Naji, N, Gloyn, A L, Lindgren, C M, Mägi, R, Morris, A P, Randall, J, Johnson, T, Elliott, P, Rybin, D, Thorleifsson, G, Steinthorsdottir, V, Henneman, P, Grallert, H, Dehghan, A, Hottenga, J J, Franklin, C S, Navarro, P, Song, K, Goel, A, Perry, J R B, Egan, J M, Lajunen, T, Grarup, N, Sparsø, T, Doney, A, Voight, B F, Stringham, H M, Li, M, Kanoni, S, Shrader, P, Cavalcanti-Proença, C, Kumari, M, Qi, L, Timpson, N J, Hayward, C, Vitart, V, Wild, S H, Morris, A, Rudan, I, Wright, A F & Campbell, H & Wilson, J F 2010, ' New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk ', Nature Genetics, vol. 42, no. 2, pp. 105-116 . https://doi.org/10.1038/ng.520Test
Nature Genetics, 42(2), 105-116. Nature Publishing Group
Yarnell, J 2010, ' New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk ' Nature Genetics, vol. 42, no. 2, pp. 105-119 . DOI: 10.1038/ng.520
Nature Genetics; Vol 42
Nature Genetics, 42(2), 105-U32. Nature Publishing Group
Nature genetics, vol. 42, no. 2, pp. 105-116
Nature Genetics, 42(5), 464-464
Nature Genetics, 42(2), 105
Dupuis, J, Langenberg, C, Prokopenko, I, Saxena, R, Soranzo, N, Jackson, A U, Wheeler, E, Glazer, N L, Bouatia-Naji, N, Gloyn, A L, Lindgren, C M, Mägi, R, Morris, A P, Randall, J, Johnson, T, Elliott, P, Rybin, D, Thorleifsson, G, Steinthorsdottir, V, Henneman, P, Grallert, H, Dehghan, A, Hottenga, J J, Franklin, C S, Navarro, P, Song, K, Goel, A, Perry, J R B, Egan, J M, Lajunen, T, Grarup, N, Sparsø, T H, Doney, A, Voight, B F, Stringham, H M, Li, M, Kanoni, S, Shrader, P, Cavalcanti-Proença, C, Kumari, M, Lu, Q, Timpson, N J, Gieger, C, Zabena, C, Rocheleau, G, Ingelsson, E, An, P, O'Connell, J, Borch-Johnsen, K, Kyvik, K O & DIAGRAM Consortium 2010, ' New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk ', Nature Genetics, vol. 42, no. 2, pp. 105-16 . https://doi.org/10.1038/ng.520Test

مصطلحات موضوعية: Blood Glucose, Netherlands Twin Register (NTR), Candidate gene, Genome-wide association study, Type 2 diabetes, CIRCADIAN CLOCK, TRIGLYCERIDE LEVELS, 0302 clinical medicine, Delta-5 Fatty Acid Desaturase, Databases, Genetic, Homeostasis, GENETICS & HEREDITY, Anders Hamsten on behalf of Procardis Consortium, Child, Genetics, PLASMA-GLUCOSE, 0303 health sciences, Glucokinase regulatory protein, COMMON VARIANTS, 11 Medical And Health Sciences, Fasting, MAGIC investigators, 3. Good health, MODEL ASSESSMENT, Life Sciences & Biomedicine, Adult, medicine.medical_specialty, ESSENTIAL COMPONENTS, Adolescent, DNA Copy Number Variations, Alleles, Blood Glucose/genetics, Blood Glucose/metabolism, DNA Copy Number Variations/genetics, Diabetes Mellitus, Type 2/genetics, Fasting/blood, Gene Expression Regulation, Genetic Loci/genetics, Genetic Predisposition to Disease, Genome-Wide Association Study, Homeostasis/genetics, Humans, Meta-Analysis as Topic, Polymorphism, Single Nucleotide/genetics, Quantitative Trait Loci/genetics, Quantitative Trait, Heritable, Reproducibility of Results, Quantitative Trait Loci, 030209 endocrinology & metabolism, Biology, DIAGRAM Consortium, INSULIN-SECRETION, Polymorphism, Single Nucleotide, Article, Fasting glucose, 03 medical and health sciences, Insulin resistance, SDG 3 - Good Health and Well-being, Diabetes mellitus, Internal medicine, genome wide association study, glucose, diabetes type 2, medicine, GIANT Consortium, Allele, GENOME-WIDE ASSOCIATION, Global BPgen Consortium, 030304 developmental biology, Glycemic, Science & Technology, genome-wide association beta-cell dysfunction plasma-glucose insulin-secretion triglyceride levels essential components model assessment common variants circadian clock disease risk, DISEASE RISK, 06 Biological Sciences, medicine.disease, Endocrinology, Diabetes Mellitus, Type 2, Genetic Loci, biology.protein, BETA-CELL DYSFUNCTION, Developmental Biology

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المؤلفون: Daniel R. Witte, Han Chen, Lori L. Bonnycastle, Mette Aadahl, Olga D. Carlson, Josée Dupuis, Yii-Der Ida Chen, Tanya M. Teslovich, Richard M. Watanabe, Frida Renström, John W. Holloway, Meena Kumari, Michael Boehnke, Audrey Y. Chu, Robert A. Scott, Alisa K. Manning, Ajay Yesupriya, Anke Tönjes, Niels Grarup, Ingegerd Johansson, Nita G. Forouhi, Inês Barroso, Aroon D. Hingorani, Dmitry Shungin, Mika Kivimäki, Weijia Xie, David Couper, Diana Marek, Peter Schwarz, Torben Hansen, Jose C. Florez, Camilla H. Sandholt, Philippe Froguel, Leif Groop, Vasiliki Lagou, Johanna Kuusisto, W. H. Linda Kao, Suzannah Bumpstead, Nabila Bouatia-Naji, Inga Prokopenko, Peter Kovacs, Zoltán Kutalik, Eric Boerwinkle, Kenneth Rice, Michael R. Erdos, Gabriele Müller, Claire Levy-Marchal, Alena Stančáková, Jürgen Grässler, Erik Ingelsson, Mario A. Morken, Gerard Waeber, Eric J. Brunner, Ulf Ekelund, Luigi Ferrucci, Francis S. Collins, Mark Walker, Laura J. Rasmussen-Torvik, Markku Laakso, Stefan Gustafsson, Stefan R. Bornstein, Guo Li, Dan E. Arking, Torben Jørgensen, Peter Vollenweider, Peter Shrader, Michael Stumvoll, Mark O. Goodarzi, Oluf Pedersen, Avan Aihie Sayer, Heather M. Stringham, Bruce M. Psaty, Claudia Langenberg, Soren Brage, Ruth J. F. Loos, David S. Siscovick, Denis Rybin, Gordon H. Williams, Caroline S. Fox, Sven Bergmann, Felicity Payne, James B. Meigs, Marie-France Hivert, Nicole L. Glazer, Jerome I. Rotter, Elaine M. Dennison, Andrew R. Wood, Göran Hallmans, Nicole F. Dowling, Peter S. Chines, Cyrus Cooper, Josephine S. Egan, Paul W. Franks, Frank B. Hu, Michael Marmot, Pedro Marques-Vidal, Kari E. North, James S. Pankow, Valeri Lyssenko, Cécile Lecoeur, Toshiko Tanaka, Daniel R. Barnes, Nicholas J. Wareham, Anna Jonsson, Bo Isomaa, Anne U. Jackson, Karen A. Jameson

المساهمون: Barnes, Daniel [0000-0002-3781-7570], Brage, Soren [0000-0002-1265-7355], Forouhi, Nita [0000-0002-5041-248X], Barroso, Ines [0000-0001-5800-4520], Wareham, Nicholas [0000-0003-1422-2993], Langenberg, Claudia [0000-0002-5017-7344], Apollo - University of Cambridge Repository, Medical Research Council (MRC)

المصدر: Scott, R A, Chu, A Y, Grarup, N, Manning, A K, Hivert, M-F, Shungin, D, Tönjes, A, Yesupriya, A, Barnes, D, Bouatia-Naji, N, Glazer, N L, Jackson, A U, Kutalik, Z, Lagou, V, Marek, D, Rasmussen-Torvik, L J, Stringham, H M, Tanaka, T, Aadahl, M, Arking, D E, Bergmann, S, Boerwinkle, E, Bonnycastle, L L, Bornstein, S R, Brunner, E, Bumpstead, S J, Brage, S, Carlson, O D, Chen, H, Chen, Y-D I, Chines, P S, Collins, F S, Couper, D J, Dennison, E M, Dowling, N F, Egan, J S, Ekelund, U, Erdos, M R, Forouhi, N G, Fox, C S, Goodarzi, M O, Grässler, J, Gustafsson, S, Hallmans, G, Hansen, T, Hingorani, A, Holloway, J W, Hu, F B, Isomaa, B, Jameson, K A, Johansson, I, Jonsson, A, Jørgensen, T, Kivimaki, M, Kovacs, P, Kumari, M, Kuusisto, J, Laakso, M, Lecoeur, C, Lévy-Marchal, C, Li, G, Loos, R J F, Lyssenko, V, Marmot, M, Marques-Vidal, P, Morken, M A, Müller, G, North, K E, Pankow, J S, Payne, F, Prokopenko, I, Psaty, B M, Renström, F, Rice, K, Rotter, J I, Rybin, D, Sandholt, C H, Sayer, A A, Shrader, P, Schwarz, P E H, Siscovick, D S, Stancáková, A, Stumvoll, M, Teslovich, T M, Waeber, G, Williams, G H, Witte, D, Wood, A R, Xie, W, Boehnke, M, Cooper, C, Ferrucci, L, Froguel, P, Groop, L, Kao, W H L, Vollenweider, P, Walker, M, Watanabe, R M, Pedersen, O, Meigs, J B, Ingelsson, E, Barroso, I, Florez, J C, Franks, P W, Dupuis, J, Wareham, N J & Langenberg, C 2012, ' No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels ', Diabetes, vol. 61, no. 5, pp. 1291-6 . https://doi.org/10.2337/db11-0973Test
Diabetes
Diabetes; Vol 61

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, DIABETES PREVENTION PROGRAM, ENDOCRINOLOGY & METABOLISM, Genotype, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Physical exercise, Single-nucleotide polymorphism, PROGRESSION, Type 2 diabetes, Biology, Motor Activity, Polymorphism, Single Nucleotide, Body Mass Index, Epigenesis, Genetic, 03 medical and health sciences, TYPE-2, MELLITUS, 0302 clinical medicine, Polymorphism (computer science), Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Allele, Life Style, POLYMORPHISMS, 030304 developmental biology, Genetic association, RISK, 0303 health sciences, ENVIRONMENT, Science & Technology, COMMON VARIANTS, Genetics/Genomes/Proteomics/Metabolomics, 11 Medical And Health Sciences, medicine.disease, Endocrinology, Gene Expression Regulation, LIFE-STYLE INTERVENTION, Body mass index, Life Sciences & Biomedicine, TRAITS

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https://pure.au.dk/portal/da/publications/no-interactions-between-previously-associated-2hour-glucose-gene-variants-and-physical-activity-or-bmi-on-2hour-glucose-levelsTest(ed20e06e-7554-4130-96c3-cf15863ea109).html