نتائج البحث - "Hillary A Keenan"

1

Renal hemodynamic dysfunction and neuropathy in longstanding type 1 diabetes: Results from the Canadian study of longevity in type 1 diabetes

المؤلفون: Yuliya Lytvyn, Rehab Albakr, Petter Bjornstad, Leif Erik Lovblom, Hongyan Liu, Julie A. Lovshin, Genevieve Boulet, Mohammed A. Farooqi, Alanna Weisman, Hillary A. Keenan, Michael H. Brent, Narinder Paul, Vera Bril, Bruce A. Perkins, David Z.I. Cherney

المصدر: Journal of diabetes and its complications. 36(11)

مصطلحات موضوعية: Adult, Canada, Endocrinology, Diabetes Mellitus, Type 1, Endocrinology, Diabetes and Metabolism, Albumins, Longevity, Internal Medicine, Hemodynamics, Humans, Diabetic Nephropathies, Glomerular Filtration Rate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0fd5422dcefb05189397c3a7ce1c69Test
https://pubmed.ncbi.nlm.nih.gov/36201892Test

2

High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes

المؤلفون: Tomas Vaisar, Angela Irwin, Karin E. Bornfeldt, George L. King, Hetal Shah, Hillary A. Keenan, I-Hsien Wu, Carla J. Greenbaum, John Gauthier, Vanessa Bahnam, Jake Wimberger, Jay W. Heinecke, Emily Wolfson, Jenny E. Kanter

المصدر: Diabetes Care

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, Lipoproteins, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, 030212 general & internal medicine, Pathophysiology/Complications, Aged, Advanced and Specialized Nursing, High concentration, Type 1 diabetes, biology, Aryldialkylphosphatase, business.industry, Cholesterol, Cholesterol, HDL, Paraoxonase, nutritional and metabolic diseases, Middle Aged, Atherosclerosis, medicine.disease, PON1, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Endocrinology, chemistry, biology.protein, Female, lipids (amino acids, peptides, and proteins), business, Diabetic Angiopathies, Ex vivo, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897d83b3cf31d6798c5e128bc886384cTest
https://doi.org/10.2337/dc19-0772Test

3

Residual β cell function and monogenic variants in long-duration type 1 diabetes patients

المؤلفون: Hillary A. Keenan, Scott G. Frodsham, Emily Wolfson, Liane J. Tinsley, Marc Gregory Yu, Stephanie D’Eon, Susan Bonner-Weir, George L. King, David M. Pober, Hetal Shah, Marcus G. Pezzolesi, Zhiheng He

المصدر: Journal of Clinical Investigation. 129:3252-3263

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f53a39aff1e316bc00fc6014f299ba2cTest
https://doi.org/10.1172/jci127397Test

4

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy

المصدر: Diabetes Care

مصطلحات موضوعية: Male, Proteomics, Endocrinology, Diabetes and Metabolism, Kidney Glomerulus, Type 2 diabetes, urologic and male genital diseases, Kidney, Cohort Studies, Diabetic nephropathy, 0302 clinical medicine, Diabetic Nephropathies, 030212 general & internal medicine, Aged, 80 and over, Middle Aged, Enzymes, Mitochondria, medicine.anatomical_structure, Disease Progression, Female, Autopsy, Metabolic Networks and Pathways, Glomerular Filtration Rate, medicine.medical_specialty, Pyruvate Kinase, 030209 endocrinology & metabolism, PKM2, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Metabolomics, Renal Insufficiency, Chronic, Pathophysiology/Complications, Aged, Advanced and Specialized Nursing, business.industry, Kidney metabolism, medicine.disease, Diabetes Mellitus, Type 1, Glucose, Endocrinology, Diabetes Mellitus, Type 2, Mitochondrial biogenesis, Case-Control Studies, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6638a6132a3c581bca05ec2d0bd71588Test
https://doi.org/10.2337/dc18-2585Test

5

Association between uric acid, renal haemodynamics and arterial stiffness over the natural history of type 1 diabetes

المؤلفون: Andrew Advani, Genevieve Boulet, Vesta Lai, Narinder Paul, Petter Bjornstad, Yuliya Lytvyn, David Z.I. Cherney, Leif E. Lovblom, Vera Bril, Julie A. Lovshin, Josephine Tse, Bruce A. Perkins, Alanna Weisman, Etienne Sochett, Mohammed A. Farooqi, Leslie Cham, Michael H. Brent, Hillary A. Keenan, Sunita K. Singh

المصدر: Diabetes Obes Metab

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Hemodynamics, Renal function, 030209 endocrinology & metabolism, Pulse Wave Analysis, 030204 cardiovascular system & hematology, Kidney, Plasma renin activity, Article, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, Vascular Stiffness, 0302 clinical medicine, Endocrinology, Internal medicine, Renin–angiotensin system, Internal Medicine, medicine, Humans, Pulse wave velocity, Aged, Retrospective Studies, Aldosterone, business.industry, Age Factors, Effective renal plasma flow, Middle Aged, medicine.disease, Uric Acid, Diabetes Mellitus, Type 1, chemistry, Cardiology, Arterial stiffness, Female, business, Glomerular Filtration Rate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631f606cc232e89885a11ba5c1415a35Test
https://doi.org/10.1111/dom.13665Test

6

The association between physical activity time and neuropathy in longstanding type 1 diabetes: A cross-sectional analysis of the Canadian study of longevity in type 1 diabetes

المؤلفون: Evan J H, Lewis, Leif E, Lovblom, Sebastien, Lanctot, Daniel, Scarr, Nancy, Cardinez, Genevieve, Boulet, Alanna, Weisman, Julie A, Lovshin, Yuliya, Lytvyn, Hillary A, Keenan, Michael H, Brent, Narinder, Paul, David Z I, Cherney, Vera, Bril, Bruce A, Perkins

المصدر: Journal of Diabetes and its Complications. 36:108134

مصطلحات موضوعية: Canada, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Endocrinology, Diabetic Neuropathies, Endocrinology, Diabetes and Metabolism, Longevity, Internal Medicine, Humans, Middle Aged, Exercise, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903728153820a9e1bacce83a5ade85dbTest
https://doi.org/10.1016/j.jdiacomp.2022.108134Test

7

The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes

المؤلفون: Alanna Weisman, Leslie Cham, Michael H. Brent, Marian Rewers, Josephine Tse, Genevieve Boulet, Hillary A. Keenan, Vera Bril, Narinder Paul, Yuliya Lytvyn, Leif E. Lovblom, Janet K. Snell-Bergeon, Andrej Orszag, David Z.I. Cherney, Bruce A. Perkins, Sunita K. Singh, Vesta Lai, Julie A. Lovshin, Petter Bjornstad

المصدر: Diabetes, Obesity and Metabolism. 21:575-583

مصطلحات موضوعية: Male, Canada, medicine.medical_specialty, Tamm–Horsfall protein, Endocrinology, Diabetes and Metabolism, Longevity, Urology, Hemodynamics, Renal function, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Lipocalin, Kidney, Article, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Lipocalin-2, Predictive Value of Tests, Internal Medicine, medicine, Humans, Diabetic Nephropathies, Aged, Aged, 80 and over, Type 1 diabetes, biology, Beta-2 microglobulin, business.industry, Effective renal plasma flow, Middle Aged, Prognosis, medicine.disease, Cross-Sectional Studies, Diabetes Mellitus, Type 1, medicine.anatomical_structure, Regional Blood Flow, Case-Control Studies, Disease Progression, Vascular resistance, biology.protein, Female, Vascular Resistance, beta 2-Microglobulin, business, Biomarkers, Glomerular Filtration Rate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a99a3e6e1865e0e9fd424700a1cd453Test
https://doi.org/10.1111/dom.13556Test

8

Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes

المؤلفون: Andrew D. Paterson, Shelley B. Bull, Hillary A. Keenan, Delnaz Roshandel, Rose Gubitosi-Klug, Ronald Klein, Barbara E.K. Klein, Angelo J. Canty, Michael N. Weedon, George L. King, Janet K. Snell-Bergeon, Marcus G. Pezzolesi, Tina Costacou, Richard A. Oram, Trevor J. Orchard, David M. Maahs

المصدر: Diabetologia

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Genome-wide association study, medicine.medical_specialty, Adolescent, Genotype, Endocrinology, Diabetes and Metabolism, Locus (genetics), Single-nucleotide polymorphism, Major histocompatibility complex, Polymorphism, Single Nucleotide, Article, Young Adult, 03 medical and health sciences, Gene Frequency, Internal medicine, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Allele, Allele frequency, Alleles, Type 1 diabetes, C-Peptide, biology, Insulin-secreting cells, Histocompatibility Antigens Class I, medicine.disease, Single nucleotide polymorphism, 3. Good health, Minor allele frequency, Cross-Sectional Studies, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Chromosomes, Human, Pair 1, biology.protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14180d6dbba4f52f5e1945969049c8a7Test
https://doi.org/10.1007/s00125-018-4555-9Test

9

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

المصدر: Nature Medicine. 23:753-762

مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, Pathology, Kidney Glomerulus, Fluorescent Antibody Technique, Kidney, Diabetic nephropathy, Mice, Diabetic Nephropathies, Glycolysis, Aged, 80 and over, Membrane Potential, Mitochondrial, Mice, Knockout, Organelle Biogenesis, Podocytes, General Medicine, Middle Aged, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Mitochondria, Gene Knockdown Techniques, Female, medicine.medical_specialty, Nitric Oxide Synthase Type III, Blotting, Western, Pyruvate Kinase, PKM2, Real-Time Polymerase Chain Reaction, General Biochemistry, Genetics and Molecular Biology, Cell Line, Diabetes Mellitus, Experimental, 03 medical and health sciences, Downregulation and upregulation, Diabetes mellitus, Internal medicine, Diabetes Mellitus, medicine, Animals, Humans, Metabolomics, Aged, business.industry, Kidney metabolism, medicine.disease, Glucose, 030104 developmental biology, Endocrinology, Mitochondrial biogenesis, Reactive Oxygen Species, business, Pyruvate kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd3154ef07976653f7361c7634c8e5dTest
https://doi.org/10.1038/nm.4328Test

10

Bone health in subjects with type 1 diabetes for more than 50 years

المؤلفون: Nicola Napoli, Mary L. Bouxsein, Liane J. Tinsley, Mogher Khamaisi, Stephanie D’Eon, Ernesto Maddaloni, Savitri M. R. Fouda, Hillary A. Keenan, Stephanie M. Hastings

المصدر: Acta Diabetologica. 54:479-488

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Aging, Bone density, Endocrinology, Diabetes and Metabolism, Osteoporosis, Cohort Studies, Fractures, Bone, Absorptiometry, Photon, 0302 clinical medicine, Endocrinology, Bone Density, Risk Factors, Bone mineral, Lumbar Vertebrae, General Medicine, Middle Aged, Photon, Type 1 diabetes, medicine.anatomical_structure, Cohort, Female, Type 1, Cohort study, Adult, Low bone mass, medicine.medical_specialty, Bone fractures, 030209 endocrinology & metabolism, Article, 03 medical and health sciences, Internal medicine, Bone mineral density, Diabetes Mellitus, Internal Medicine, medicine, Humans, Absorptiometry, Bone, Triglycerides, Femoral neck, business.industry, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Relative risk, business, Fractures

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6626a7787485316907610ac6955ba464Test
https://doi.org/10.1007/s00592-017-0973-2Test

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