المؤلفون: Justine Gillard, Laure-Alix Clerbaux, Bart Staels, Anne Tailleux, Isabelle Leclercq, Laure B. Bindels, Maxime Nachit, Christine Sempoux

المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie

المصدر: JHEP reports, vol. 4, no. 1, pp. 100387
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reports

مصطلحات موضوعية: HFD, high-fat diet, CYP7A1, CYP8B1, sterol 12α-hydroxylase, WDF, western and high-fructose diet, FABP6, OGTT, oral glucose tolerance test, FGF15, RC799-869, ASBT, apical sodium-dependent BA transporter, chemistry.chemical_compound, OST, organic solute transporter, βMCA, β-muricholic acid, SHP, small heterodimer protein, WDF, CYP27A1, SHP, TNFα, Immunology and Allergy, LCA, lithocholic acid, DCA, FABP6, fatty acid binding protein 6, FGFR4, fibroblast growth factor receptor 4, CA, cholic acid, NAS, NAFLD activity score, CA, CYP7B1, CYP7B1, oxysterol 7α-hydroxylase, Bile acid, WT, αMCA, ND, normal diet, TGR5, Takeda G-protein coupled receptor 5, Chemistry, LCA, Deoxycholic acid, TLCA, TGR5, Gastroenterology, NASH, GLP-1, glucagon-like peptide-1, Diseases of the digestive system. Gastroenterology, G protein-coupled bile acid receptor, TNFα, tumor necrosis factor α, FXR, BA, bile acid, LPS, lipopolysaccharide, Research Article, CYP2A12, bile acid 7α-hydroxylase, ωMCA, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ωMCA, ω-muricholic acid, LPS, normal diet, Normal diet, βMCA, medicine.drug_class, NASH, non-alcoholic steatohepatitis, education, tumor necrosis factor α, BA, digestive system, metabolic syndrome, CDCA, chenodeoxycholic acid, CYP2A12, CYP27A1, sterol 27-hydroxylase, Internal medicine, NAFLD, Internal Medicine, medicine, OGTT, CYP7A1, cholesterol 7α-hydroxylase, DCA, deoxycholic acid, FGF15, fibroblast growth factor 15, FXR, Farnesoid X receptor, TLCA, tauro-lithocholic acid, WT, wild-type, αMCA, α-muricholic acid, wild-type, CYP8B1, Hepatology, OST, medicine.disease, Endocrinology, NAS, FGFR4, CDCA, HFD, ND, Steatohepatitis, GLP-1, ASBT

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f803f3cd8976e73d533d8b1885ead5Test
https://serval.unil.ch/notice/serval:BIB_8BED7E41CA16Test

المؤلفون: Ellie Northall, Banumathi K. Cole, John E. Reardon, Brian R. Wamhoff, Matthew W. Olson, Stephen A. Hoang, Kae Matsuda, Ulrich L. Günther, Mark J. Lawson, Ryan E. Feaver, Jason Pickens, Patricia F. Lalor, Raquel Saborano, Robert A. Figler, Hiroaki Yashiro, Derek M. Erion, Hitomi Ogino, Emma L. Shepherd, Gideon M. Hirschfield, Nobuhiro Nishigaki

المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100217-(2021)
JHEP Reports

مصطلحات موضوعية: ALD, alcohol-related cirrhosis, IGF, insulin-like growth factor, PDGF, platelet-derived growth factor, chemistry.chemical_compound, Fibrosis, AST, aspartate transaminase, Immunology and Allergy, Glycolysis, Liver injury, G/F, glucose/fructose, biology, TG, triglyceride, Fatty liver, Gastroenterology, NASH, HSQC, heteronuclear single quantum coherence, CT, computed tomography, aLMF, activated liver myofibroblasts, HSCs, hepatic stellate cells, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, FIB4, fibrosis-4, DNL, de novo lipogenesis, Fructose, Internal medicine, NAFLD, Internal Medicine, medicine, TGFB, transforming growth factor beta, lcsh:RC799-869, APRI, AST to Platelet Ratio Index, NPCs, non-parenchymal cells, KO, knockout, Hepatology, business.industry, medicine.disease, WT, wild-type, KHK, ketohexokinase, HSECs, hepatic sinusoidal endothelial cells, Treatment, Endocrinology, PSC, primary sclerosing cholangitis, Metabolism, chemistry, Alanine transaminase, Hepatic stellate cell, biology.protein, BSA, bovine serum albumin, TIMP-1, Tissue Inhibitor of Matrix metalloproteinase-1, lcsh:Diseases of the digestive system. Gastroenterology, PBC, primary biliary cholangitis, Steatosis, business, BEC, biliary epithelial cells, LGLI, low glucose and insulin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e901d5e74295d49cc1586ef5be254eTest
http://www.sciencedirect.com/science/article/pii/S2589555920301518Test

المؤلفون: Hsiao D. Lieu, Gideon M. Hirschfield, Arun J. Sanyal, Stephen A. Harrison, Lei Ling, Ulrich Beuers, Alex M. DePaoli

المساهمون: Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier

مصطلحات موضوعية: Fibroblast growth factor, RC799-869, AST, aspartate aminotransferase, chemistry.chemical_compound, Chenodeoxycholic acid, GCA, glycocholic acid, Immunology and Allergy, Bile acid synthesis, LCA, lithocholic acid, NASH CRN, NASH Clinical Research Network, Non-alcoholic steatohepatitis, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, GCDCA, glycochenodeoxycholic acid, Bile acid, Primary sclerosing cholangitis, Deoxycholic acid, Gastroenterology, ELF test, Enhanced Liver Fibrosis test, Diseases of the digestive system. Gastroenterology, Ursodeoxycholic acid, FGF19, fibroblast growth factor 19, Glycodeoxycholic acid, G/T ratio, ratio of glycine to taurine conjugates of bile acids, NAS, non-alcoholic fatty liver disease activity score, BAAT, bile acid-CoA:amino acid N-acyltransferase, TDCA, taurodeoxycholic acid, medicine.drug, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TCA, taurocholic acid, Glycocholic acid, digestive system, Pro-C3, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, Internal medicine, ALT, alanine aminotransferase, Internal Medicine, medicine, MRI-PDFF, magnetic resonance imaging-proton density fat fraction, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, Hepatology, ALP, alkaline phosphatase, Cholic acid, FGF19, Fibrogenesis, Endocrinology, PSC, primary sclerosing cholangitis, chemistry, DCA, deoxycholic acid, Pro-C3, neoepitope-specific N-terminal pro-peptide of type III collagen, TLCA, taurolithocholic acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7001e197981d0d939e7dc5af50542fTest
https://pubmed.ncbi.nlm.nih.gov/33898959Test

المؤلفون: Hideo Suzuki, Fumihiko Uchida, Kiyoji Tanaka, Takeji Sakae, Sechang Oh, Bokun Kim, Takehiko Tsujimoto, Junichi Shoda, Seiichiro Iizumi, Tomonori Isobe

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100253-(2021)

مصطلحات موضوعية: FGF21, Adipose tissue, RC799-869, AST, aspartate aminotransferase, WFA+-M2BP, Wisteria floribunda agglutinin-positive human Mac-2 binding protein, NEFAs, non-esterified fatty acids, GGT, gamma-glutamyl transpeptidase, Weight loss, WC, waist circumference, Immunology and Allergy, Medicine, HO1, heme oxygenase 1, GPx, glutathione peroxidase, TNF-α, tumour necrosis factor alpha, Fatty liver, Gastroenterology, VAT, visceral adipose tissue, Diseases of the digestive system. Gastroenterology, TEI, total energy intake, TG, triglycerides, GCLM, glutamate-cysteine ligase modifier subunit, Esub, exercise (subset for which biological samples were available) group, Esmall, small amount of exercise group, Wtotal, weight-loss group, TBARS, thiobarbituric acid-reactive substances, BDNF, brain-derived neurotrophic factor, LPS, lipopolysaccharide, CAP, controlled attenuation parameter, NF-Score, NAFLD fibrosis score, medicine.symptom, Research Article, FAST-Score, FibroScan-AST score, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, LSM, liver stiffness measured using transient elastography, Hepatokine, FGF-21, fibroblast growth factor-21, Dietary restriction, NASH, non-alcoholic steatohepatitis, Elarge, large amount of exercise group, MVPA, moderate-to-vigorous intensity physical activity, SPARC, secreted protein acidic and rich in cysteine, NQO1, NAD(P)H quinone oxidoreductase, Myokine, ALT, alanine aminotransferase, Internal medicine, Internal Medicine, Aerobic exercise, Liver fat, Etotal, exercise group, FPG, fasting plasma glucose, KC, Kupffer cells, Se-P, selenoprotein-P, PBMCs, peripheral blood mononuclear cells, Nuclear factor-erythroid 2-related factor 2, Hepatology, Adiponectin, business.industry, Nrf2, nuclear factor E2-related factor 2, Wsub, weight-loss (subset for which biological samples were available) group, medicine.disease, HOMA-IR, homeostasis model assessment-insulin resistance, Regimen, Endocrinology, mnSOD, manganese superoxide dismutase, ANGPTL6, angiopoietin-like 6, Liver stiffness, business, GCLC, glutamate-cysteine ligase catalytic subunit

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d799758e6591ac117326fd2a92b672f8Test
https://tsukuba.repo.nii.ac.jp/records/2004615Test

المؤلفون: Irene Locatelli, Francesco Vizzutti, N. Navari, Emanuele Albano, Alessandra Caligiuri, Erica Novo, Maurizio Parola, Massimo Pinzani, W. Delogu, E. Zamara, Fabio Marra, Salvatore Sutti, S. Galastri, E. Vivoli, A. Provenzano, Stefano Milani

المصدر: Clinical Science (London, England : 1979)
Clinical Science
Clinical Science; Vol 123

مصطلحات موضوعية: Liver Cirrhosis, HNE, 4-hydroxynonenal, IFN-γ, interferon-γ, Adipose tissue, AST, aspartate aminotransferase, iNOS, inducible NO synthase, chemistry.chemical_compound, Mice, 0302 clinical medicine, CC chemokine ligand 2, Fibrosis, Transforming Growth Factor beta, cytokine, Chemokine CCL2, liver fibrosis, Mice, Knockout, 0303 health sciences, TIMP-1, tissue inhibitor of metalloproteinases-1, Mice, Inbred BALB C, Fatty liver, CCL2, CC chemokine ligand 2, General Medicine, MGL1, macrophage galactose-type C-type lectin 1, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, TNFα, tumour necrosis factor α, 030211 gastroenterology & hepatology, non-alcoholic steatohepatitis, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Biology, S2, Collagen Type I, 03 medical and health sciences, ROS, reactive oxygen species, Species Specificity, Internal medicine, TGF-β, transforming growth factor-β, medicine, Hepatic Stellate Cells, Animals, Sirius Red, 030304 developmental biology, KO, knockout, Tissue Inhibitor of Metalloproteinase-1, Macrophages, chemokine, medicine.disease, WT, wild-type, Dietary Fats, IL, interleukin, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, Oxidative Stress, Endocrinology, chemistry, Alanine transaminase, Immunology, CCR2, CC chemokine receptor 2, Hepatic stellate cell, biology.protein, Steatosis, Steatohepatitis, RT, real-time, FAM, 6-carboxyfluorescein, MCD diet, methionine/choline-deficient diet

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301da5ba54f78553e0c47b589df9625Test
http://europepmc.org/articles/PMC3369401Test

المؤلفون: Shannon M. Bailey, Heather B. Eccleston, David W. Kraus, Victor M. Darley-Usmar, Sudheer K. Mantena, Jeannette E. Doeller, Kelly K. Andringa, Adrienne L. King, Denty Paul Vaughn, Gary A. Abrams

المصدر: Biochemical Journal

مصطلحات موضوعية: Male, Bioenergetics, Nitric Oxide Synthase Type II, Mitochondria, Liver, Mitochondrion, medicine.disease_cause, Biochemistry, JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol carbo-cyanine iodide, chemistry.chemical_compound, Mice, 0302 clinical medicine, HFD, high fat diet, cytochrome c oxidase, 3-NT, 3-nitrotyrosine, Hypoxia, Membrane Potential, Mitochondrial, 0303 health sciences, Fatty liver, CYP2E1, cytochrome P450 2E1, Cytochrome P-450 CYP2E1, 3. Good health, mitochondria, FCCP, carbonyl cyanide p-trifluoromethoxyphenylhydrazone, 030220 oncology & carcinogenesis, iNOS, inducible nitric oxide synthase, non-alcoholic steatohepatitis, RCR, respiratory control ratio, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Cellular respiration, NASH, non-alcoholic steatohepatitis, Cell Respiration, Biology, liver, Nitric Oxide, Nitric oxide, PAPA NONOate, 1-propanamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazino), DAB, diaminobenzidine, RNS, reactive nitrogen species, Mitochondrial Proteins, 03 medical and health sciences, ROS, reactive oxygen species, Internal medicine, medicine, Animals, Molecular Biology, Reactive nitrogen species, 030304 developmental biology, nutritional and metabolic diseases, Cell Biology, medicine.disease, Dietary Fats, Fatty Liver, Mice, Inbred C57BL, Oxidative Stress, Endocrinology, chemistry, Tyrosine, Steatohepatitis, Oxidative stress, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8ad50b2a6a6f4a72113fc86354941bTest
http://europepmc.org/articles/PMC2637578Test

المؤلفون: Felix Stickel, Maria L. Balmer, Jeannine Joneli, Wolfgang Thormann, Alain M. Schoepfer, Jean-François Dufour

المصدر: Clinical Science (London, England : 1979)
Clinical science (London England : 1979)

مصطلحات موضوعية: Liver Cirrhosis, Male, Cirrhosis, BMI, body mass index, AST, aspartate aminotransferase, Serum Hyaluronic Acid, Chronic liver disease, Body Mass Index, Liver disease, 0302 clinical medicine, Blood serum, hepatic fibrosis, AdipoR, adiponectin receptor, Prospective Studies, Hyaluronic Acid, 2. Zero hunger, 0303 health sciences, Anthropometry, Liver Diseases, Fatty liver, General Medicine, Middle Aged, 3. Good health, TG, triacylglycerol, HOMA, homoeostasis model assessment, Elasticity Imaging Techniques, 030211 gastroenterology & hepatology, Female, non-alcoholic fatty liver disease (NAFLD), Research Article, Adult, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ANCOVA, analysis of covariance, NASH, non-alcoholic steatohepatitis, S7, S3, metabolic syndrome, Bile Acids and Salts, Diagnosis, Differential, 03 medical and health sciences, Sex Factors, Internal medicine, ALT, alanine aminotransferase, medicine, Humans, 030304 developmental biology, Adiponectin, adiponectin, business.industry, cirrhosis, nutritional and metabolic diseases, chronic liver disease, medicine.disease, Fatty Liver, Endocrinology, Chronic Disease, Steatohepatitis, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57760eaf2f7c8755862836a259985d38Test
https://pubmed.ncbi.nlm.nih.gov/20524936Test

المؤلفون: Michael Trauner, Hanns-Ulrich Marschall, Curt Einarsson, Anders Thorell, Tatjana Stojakovic, Pooja Jha, Guenter Fauler, Thierry Claudel, Bastian Hoesel, Michaela Mueller, Harald Koefeler, Carolin Lackner

المصدر: Journal of Hepatology

مصطلحات موضوعية: vWAT, visceral white adipose tissue, C4, 7α-hydroxy-4-cholesten-3-one, FASN, fatty acid synthase, Receptors, Cytoplasmic and Nuclear, FGF19, SHP, small heterodimer partner, LDLR, low density lipoprotein receptor, chemistry.chemical_compound, SA, stearic acid, CA, cholic acid, TGs, triglycerides, Bile acid, Chemistry, ABC, ATP-binding cassette, MTTP, microsomal triglyceride transfer protein, Ursodeoxycholic Acid, FGF19, fibroblast growth factor 19, Ursodeoxycholic acid, Obesity, Morbid, 3. Good health, Stearoyl-CoA desaturase, HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase, lipids (amino acids, peptides, and proteins), Research Article, medicine.drug, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, MA, myristic acid, FAs, fatty acides, medicine.drug_class, NASH, non-alcoholic steatohepatitis, Cholesterol 7 alpha-hydroxylase, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, Bile Acids and Salts, PA, palmitic acid, FXR, farnesoid X receptor, nCEH, neutral cholesterol ester hydrolase, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, medicine, Humans, ApoB, apolipoprotein B, SREBP1c, sterol regulatory element-binding protein-1c, Liver X receptor, ComputingMethodologies_COMPUTERGRAPHICS, VLDL, very low density lipoproteins, Hepatology, BAs, bile acids, Lipogenesis, OA, oleic acid, Lipid metabolism, CYP7A1, cholesterol 7α-hydroxylase, Lipid Metabolism, FATP1, fatty acid transport protein 1, Endocrinology, 3-hydroxy-3-methylglutaryl-CoA reductase, Farnesoid X receptor, SCD, stearoyl-Coa desaturase, Non-alcoholic fatty liver disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd82151b619f124808fea36eb0c8125dTest