المؤلفون: Mingxi Weng, Sik Y. Ho, Xiaoxiao Yang, Yanpu Chen, Derek Hoi Hang Ho, Ralf Jauch, Jian Yan, Hans R. Schöler, Johannes Graumann, Gary D. Stormo, Yogesh Srivastava, Anastasia Bednarz, Ya Gao, Yuanjie Wei, Sergiy Velychko, Thomas Braun, Daisylyn Senna Tan, Johnny Kim, Vikas Malik, Ligang Fan

المصدر: Molecular Biology and Evolution

مصطلحات موضوعية: Cell fate determination, Biology, AcademicSubjects/SCI01180, Kruppel-Like Factor 4, Mice, 03 medical and health sciences, 0302 clinical medicine, SOX2, Genetics, Animals, Cellular Reprogramming Techniques, Molecular Biology, Transcription factor, Discoveries, transcription factor, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, POU domain, molecular evolution, fungi, Pioneer factor, Transdifferentiation, AcademicSubjects/SCI01130, reprogramming, protein engineering, POU, Cell biology, cell fate conversion, KLF4, POU Domain Factors, embryonic structures, Directed Molecular Evolution, Reprogramming, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a59703c3bb3cce02eb205c63ea6683dTest
https://doi.org/10.1093/molbev/msab075Test

المؤلفون: Vlad Cojocaru, Vikas Malik, Daisylyn Senna Tan, Mingxi Weng, Yogesh Srivastava, Lydia W.T. Cheung, Ralf Jauch, Guangming Wu, Asif Javed, Veeramohan Veerapandian

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: FEBS Journal, 287(1), 122-144. Wiley-Blackwell

مصطلحات موضوعية: 0301 basic medicine, Cells, Induced Pluripotent Stem Cells, Mutation, Missense, Biology, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, SOX2, Induced Pluripotent Stem Cells/cytology, Neoplasms, SOXF Transcription Factors, Missense mutation, Animals, Humans, Induced pluripotent stem cell, Molecular Biology, Transcription factor, Cells, Cultured, Embryonic Stem Cells, Cultured, Embryonic Stem Cells/cytology, POU domain, Point mutation, SOXB1 Transcription Factors, Gene Expression Profiling, Cell Differentiation, Cell Biology, Cellular Reprogramming, Embryonic stem cell, Neoplasms/genetics, Cell biology, 030104 developmental biology, 030220 oncology & carcinogenesis, SOXB1 Transcription Factors/genetics, embryonic structures, Mutation, SOXF Transcription Factors/genetics, Missense, Reprogramming, Octamer Transcription Factor-3, Octamer Transcription Factor-3/genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c03752ac8a860e61b55539192c5c6Test
https://hdl.handle.net/20.500.11755/71f1888a-7614-4101-8c39-09d156b776c5Test

المؤلفون: Zahir Shah, Sebastian Pott, Dennis Zimmer, Vikas Malik, Veeramohan Veerapandian, Miguel A. Esteban, Sergiy Velychko, Markus Holzner, Marius Arend, Mingxi Weng, Sebastiaan H. Meijsing, Yogesh Srivastava, Ralf Jauch, Laura V. Glaser, Yanpu Chen, Andrew P. Hutchins, Huating Wang, Jiekai Chen, Hans R. Schöler

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: 0301 basic medicine, Time Factors, cells, General Physics and Astronomy, Stem cells, 02 engineering and technology, medicine.disease_cause, Gene regulatory networks, lcsh:Science, Cells, Cultured, reproductive and urinary physiology, Mutation, Multidisciplinary, Cellular Reprogramming, 021001 nanoscience & nanotechnology, Chromatin, Cell biology, KLF4, embryonic structures, biological phenomena, cell phenomena, and immunity, 0210 nano-technology, Reprogramming, Epithelial-Mesenchymal Transition, Science, Induced Pluripotent Stem Cells, Primary Cell Culture, Mice, Transgenic, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Kruppel-Like Factor 4, 03 medical and health sciences, stomatognathic system, SOX2, medicine, Animals, Gene silencing, Enhancer, POU domain, SOXB1 Transcription Factors, fungi, General Chemistry, Fibroblasts, Embryo, Mammalian, 030104 developmental biology, Octamer Transcription Factor-6, lcsh:Q, sense organs, Protein Multimerization, Octamer Transcription Factor-3

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95564dd529158482eb3683b451d2c99dTest
https://hdl.handle.net/21.11116/0000-0005-9084-221.11116/0000-0005-9086-0Test

المؤلفون: Ralf Jauch, Vikas Malik, Dennis Zimmer

المصدر: Cellular and Molecular Life Sciences. 75:1587-1612

مصطلحات موضوعية: 0301 basic medicine, Context (language use), Computational biology, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, Animals, Humans, Molecular Biology, Gene, Transcription factor, Pharmacology, Binding Sites, POU domain, fungi, Cell Differentiation, Cell Biology, DNA-binding domain, Cellular Reprogramming, Chromatin, DNA binding site, 030104 developmental biology, POU Domain Factors, embryonic structures, Molecular Medicine, Reprogramming, Protein Binding, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7246bcc17ccacaf707bcc455881413Test
https://doi.org/10.1007/s00018-018-2748-5Test

المؤلفون: Yujia Tang, Zhongzhou Yang, Fei Gao, Xue Wen, Yinghua Huang, Jiekai Chen, Vikas Malik, Xiaofen Huang, Miguel A. Esteban, Andrew P. Hutchins, Lulu Wang, Giacomo Volpe, Isaac A. Babarinde, Guanyu Ji, Chuanqing Tang, Hui Zhang, Carl Ward, Xichen Bao, Liangxue Lai, Lin Guo, Giuseppe Testa, Baohua Liu, Tanveer Ahmed, Shizuo Akira, Yingying Li, Duanqing Pei, Baoming Qin, Meifang Pan, Jianbin Su, Ji-Fan Hu, Xinyu Wu, Xueting Xu, Hui Zheng, Takashi Satoh, Yiwei Lai, Ralf Jauch, Runxia Lin, Li Sun, Guangjin Pan, Xiaogan Qin, Jinlong Chen

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: 0301 basic medicine, Jumonji Domain-Containing Histone Demethylases, General Physics and Astronomy, Histones, Mice, 0302 clinical medicine, Histone post-translational modifications, lcsh:Science, Promoter Regions, Genetic, Cellular Senescence, Regulation of gene expression, Multidisciplinary, Genome, Gene Expression Regulation, Developmental, Cellular Reprogramming, humanities, Chromatin, Cell biology, Enhancer Elements, Genetic, KLF4, embryonic structures, Epigenetics, biological phenomena, cell phenomena, and immunity, Reprogramming, Pluripotent Stem Cells, Transcriptional Activation, Science, Kruppel-Like Transcription Factors, Biology, Models, Biological, Chromatin structure, General Biochemistry, Genetics and Molecular Biology, Catalysis, Article, 03 medical and health sciences, Kruppel-Like Factor 4, SOX2, Animals, Cell Proliferation, Cohesin loading, Lysine, Epithelial Cells, General Chemistry, Fibroblasts, Demethylation, Gene regulation, 030104 developmental biology, biology.protein, Demethylase, lcsh:Q, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce28b18192adb32089c843f7075da5Test
https://pubmed.ncbi.nlm.nih.gov/33033262Test

المؤلفون: Shinsuke Ohba, Danny Chan, Zhijia Tan, Ben Niu, Andrew P. McMahon, Ralf Jauch, Xinjun He, Kwok Yeung Tsang, Kathryn S.E. Cheah, Cheng Wang, Yong-Heng Huang, Michael Q. Zhang, Ian G. Melhado

المصدر: PLoS Genetics
PLoS Genetics, Vol 14, Iss 4, p e1007346 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cellular differentiation, Gene Expression, Transactivation, Database and Informatics Methods, Mice, 0302 clinical medicine, Cell Signaling, Animal Cells, Transcriptional regulation, Medicine and Health Sciences, Gene Regulatory Networks, Growth Plate, Genetics (clinical), Connective Tissue Cells, Regulation of gene expression, Bone growth, integumentary system, MEF2 Transcription Factors, Physics, Transcriptional Control, Cell Differentiation, SOX9 Transcription Factor, musculoskeletal system, Cell biology, Physical sciences, AP-1 transcription factor, Chemistry, medicine.anatomical_structure, Connective Tissue, embryonic structures, Hepatocyte Nuclear Factor 3-beta, Female, Anatomy, Cellular Types, Sequence Analysis, Chondrogenesis, Research Article, Signal Transduction, Mef2, Transcriptional Activation, endocrine system, animal structures, lcsh:QH426-470, Bioinformatics, Chemical physics, Biology, Research and Analysis Methods, Models, Biological, Zinc Finger Protein GLI1, Chondrocyte, 03 medical and health sciences, Chondrocytes, Sequence Motif Analysis, medicine, Genetics, Animals, Gene Regulation, Bone, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Bone Development, SOX9-GLI-FOXA phasic transcriptional network, Biology and Life Sciences, Core Binding Factor alpha Subunits, Dimers (Chemical physics), Cell Biology, Mice, Inbred C57BL, lcsh:Genetics, 030104 developmental biology, Biological Tissue, Cartilage, Hedgehog Signaling, Mice, Inbred CBA, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af65c69e44daadf3530596849a8204aTest
http://europepmc.org/articles/PMC5919691Test

المؤلفون: Barath Udayasuryan, Konstantin Pervushin, Prasanna R. Kolatkar, Vlad Cojocaru, Veeramohan Veerapandian, Kamesh Narasimhan, Sriram Jayabal, Yong-Heng Huang, Shubhadra Pillay, Ralf Jauch

المساهمون: School of Biological Sciences

المصدر: Nucleic Acids Research

مصطلحات موضوعية: PAX6 Transcription Factor, genetic structures, Molecular Sequence Data, Repressor, Electrophoretic Mobility Shift Assay, Cooperativity, Enhancer RNAs, Computational biology, Biology, chemistry.chemical_compound, Genetics, Humans, Paired Box Transcription Factors, Amino Acid Sequence, Eye Proteins, Enhancer, Nuclear Magnetic Resonance, Biomolecular, Transcription factor, DNA Primers, Homeodomain Proteins, Base Sequence, Sequence Homology, Amino Acid, SOXB1 Transcription Factors, Gene regulation, Chromatin and Epigenetics, DNA, Biological Sciences, Repressor Proteins, Enhancer Elements, Genetic, chemistry, embryonic structures, Human genome, sense organs, PAX6

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3380dab764d4308ec00141df46fd9dddTest
https://doi.org/10.1093/nar/gku1390Test

المؤلفون: Ralf Jauch, Hans R. Schöler, Vlad Cojocaru, Veeramohan Veerapandian, Felipe Merino, Calista Keow Leng Ng

المصدر: Structure. 22:1274-1286

مصطلحات موضوعية: animal structures, Cellular differentiation, Molecular Sequence Data, Mutant, Cooperativity, Plasma protein binding, Molecular Dynamics Simulation, Biology, Mice, chemistry.chemical_compound, SOX2, Structural Biology, HMGB Proteins, Consensus Sequence, SOXF Transcription Factors, Consensus sequence, Animals, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, Peptide sequence, reproductive and urinary physiology, Genetics, Base Sequence, SOXB1 Transcription Factors, Stem Cells, fungi, Cell Differentiation, DNA, Cell biology, chemistry, embryonic structures, Thermodynamics, biological phenomena, cell phenomena, and immunity, Hydrophobic and Hydrophilic Interactions, Octamer Transcription Factor-3, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b619acba7443166aef10d14d1e9b81feTest
https://doi.org/10.1016/j.str.2014.06.014Test

المؤلفون: Caizhen Hu, Xiaoxiao Yang, Yiming K. Chang, Gary D. Stormo, Yogesh Srivastava, Adam P. Joyce, Zheng Zuo, Ralf Jauch, James J. Havranek

المصدر: Nucleic Acids Research

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, Cooperativity, Computational biology, Plasma protein binding, Biology, DNA sequencing, 03 medical and health sciences, Mice, 0302 clinical medicine, Protein structure, Genetics, Animals, Transcription factor, Molecular Biology, SOX Transcription Factors, Regulation of gene expression, POU domain, SOXB1 Transcription Factors, Cooperative binding, DNA, 030104 developmental biology, embryonic structures, POU Domain Factors, Protein Multimerization, Octamer Transcription Factor-3, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5671133608b18795c96268adef43f485Test
https://pubmed.ncbi.nlm.nih.gov/27915232Test

المؤلفون: Andrew Tai, Martin Cheung, Kathryn S.E. Cheah, Ralf Jauch, Marianne E. Bronner, Yong-Heng Huang

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Transcriptional Activation, Neural Tube, Molecular Conformation, Chordate, Chick Embryo, SOXE Transcription Factors, Article, 03 medical and health sciences, Transactivation, Species Specificity, Cell Movement, Gene Duplication, Gene duplication, medicine, Animals, Humans, Phylogeny, Lancelets, Genetics, Neurons, Likelihood Functions, Multidisciplinary, biology, Neural tube, Neural crest, Gene Expression Regulation, Developmental, biology.organism_classification, Biological Evolution, 030104 developmental biology, medicine.anatomical_structure, Evolutionary biology, Neural Crest, embryonic structures, Vertebrates, Neofunctionalization, Protein Multimerization, Neural plate, Neuroglia

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a8eff0f841768fdb7105a4c6e42c1bTest
http://europepmc.org/articles/PMC5062122Test