Structural Similarity and Probabilistic Neural Network Based Human G -Band Chromosomes Classification
العنوان: | Structural Similarity and Probabilistic Neural Network Based Human G -Band Chromosomes Classification |
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المؤلفون: | N Kumaresan, D. Somasundaram, S Sacikala, Vinodhini Subramanian |
المصدر: | INTERNATIONAL JOURNAL OF HUMAN GENETICS. 18 |
بيانات النشر: | Kamla Raj Enterprises, 2018. |
سنة النشر: | 2018 |
مصطلحات موضوعية: | business.industry, Structural similarity, Computer science, Chromosome, Pattern recognition, Karyotype, Object (computer science), Support vector machine, Probabilistic neural network, Chromosome analysis, Centromere, Genetics, Artificial intelligence, business, Electrical Engineering, Genetics (clinical) |
الوصف: | Chromosome classification has a vital role to play in achieving karyotype. Generally, human chromosomes consists of 46 chromosomes. Karyotyping is the important clinical procedure for screening and diagnosing genetic disorders and cancer. Manual karyotyping is a labor-insensitive and time-consuming task hence, developing automated computer-assisted systems have gained importance. In past decade, chromosome length and centromere positions were considered for classification. In chromosome analysis it is essential to segment the object of interest from the background. This object often consists of two or more chromosomes, either touching, overlapping or multiple overlapping with each other. In this paper, dataset of 1000 touching chromosomes, 1000 overlapping and 500 multiple overlapping chromosomes are taken for the study. SVM and Probabilistic Neural Network (PNN)-based classification is carried out and compared with other classifiers. PNN provides ninety-seven percent of classification accuracy and proves to be better compared to other classifiers. |
وصف الملف: | application/pdf |
تدمد: | 2456-6330 0972-3757 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ffa2d13297c84dd90fd2c67947eb15Test https://doi.org/10.31901/24566330.2018/18.3.704Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....37ffa2d13297c84dd90fd2c67947eb15 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 24566330 09723757 |
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