نتائج البحث - "physiologically based pharmacokinetics"

المصدر: Effinger, A, O'Driscoll, C M, McAllister, M & Fotaki, N 2021, ' Predicting budesonide performance in healthy subjects and patients with Crohn's disease using biorelevant in vitro dissolution testing and PBPK modeling ', European Journal of Pharmaceutical Sciences, vol. 157, 105617 . https://doi.org/10.1016/j.ejps.2020.105617Test

مصطلحات موضوعية: Budesonide, Drug, Physiologically based pharmacokinetic modelling, Bioavailability, media_common.quotation_subject, Population, Pharmaceutical Science, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Inflammatory bowel disease, Models, Biological, Absorption, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, SDG 3 - Good Health and Well-being, Crohn Disease, medicine, Humans, Computer Simulation, Pharmacokinetic modeling, education, media_common, education.field_of_study, CYP3A4, business.industry, Inflammatory Bowel Disease, 021001 nanoscience & nanotechnology, medicine.disease, Healthy Volunteers, 3. Good health, Solubility, Physiologically based pharmacokinetics, 0210 nano-technology, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd94a99a39e27b01d703a635a49f54f4Test
https://pubmed.ncbi.nlm.nih.gov/33164838Test

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Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

المؤلفون: Titus Mohan, Michael D. Wiese, Porntipa Korprasertthaworn, Geoffrey T. Tucker, Andrew Rowland, Thomas M. Polasek, Michael J. Sorich, Amin Rostami-Hodjegan, Vidya Perera

المساهمون: Polasek, Thomas M, Tucker, Geoffrey T, Sorich, Michael J, Wiese, Michael D, Mohan, Titus, Rostami-Hodjegan, Amin, Korprasertthaworn, Porntipa, Perera, Vidya, Rowland, Andrew

المصدر: British Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, Oncology, Olanzapine, PBPK, Physiologically based pharmacokinetic modelling, medicine.medical_specialty, Genotype, Coefficient of variation, dose prediction, olanzapine, Population, physiologically based pharmacokinetics, Models, Biological, 030226 pharmacology & pharmacy, White People, Cytochrome P-450 CYP2C8, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Asian People, Pharmacokinetics, Internal medicine, medicine, Humans, Computer Simulation, Pharmacology (medical), Dosing, education, Aged, Pharmacology, education.field_of_study, medicine.diagnostic_test, business.industry, personalized medicine, Middle Aged, Regimen, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Female, Drug Monitoring, business, Antipsychotic Agents, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900b2c796dd2b1c641ac76fe5a24f39Test
https://doi.org/10.1111/bcp.13480Test

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Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body

المؤلفون: Dong-Hua Yang, Tasneem Ahmad, Najia Mansoor, Martin Czejka, Mansoor Ahmed, Yingfang Fan, Syed Sharib, Rafeeq Alam Khan

المصدر: Oncotarget

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749e07baa696d09deac3652ee0836b15Test
https://doi.org/10.18632/oncotarget.18380Test

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Accounting for inter-correlation between enzyme abundance: a simulation study to assess implications on global sensitivity analysis within physiologically-based pharmacokinetics

المؤلفون: Adam S. Darwich, Nicola Melillo, Paolo Magni, Amin Rostami-Hodjegan

المصدر: Melillo, N, Darwich, A S, Magni, P & Rostami-hodjegan, A 2019, ' Accounting for inter-correlation between enzyme abundance: a simulation study to assess implications on global sensitivity analysis within physiologically-based pharmacokinetics ', Journal of pharmacokinetics and pharmacodynamics . https://doi.org/10.1007/s10928-019-09627-6Test

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Population, Biological Availability, Computational biology, Biology, 030226 pharmacology & pharmacy, Models, Biological, Correlation, Cytochrome P-450 CYP2C8, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Piperidines, medicine, Cytochrome P-450 CYP3A, Humans, Computer Simulation, education, Pharmacology, education.field_of_study, CYP3A4, Liver-Specific Organic Anion Transporter 1, Repaglinide, Confidence interval, Bioavailability, Enzymes, Liver, Pharmaceutical Preparations, Global sensitivity analysis, 030220 oncology & carcinogenesis, Inactivation, Metabolic, Physiologically based pharmacokinetics, Carbamates, Simulation, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba236810a2c2e62b4ab33f3506a83caTest
https://doi.org/10.1007/s10928-019-09627-6Test

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Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System

المؤلفون: Swapnil Khadke, Raj K.S. Badhan, Yvonne Perrie

المصدر: Pharmaceutics
Pharmaceutics; Volume 9; Issue 4; Pages: 57
Pharmaceutics, Vol 9, Iss 4, p 57 (2017)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d82297c446dda021abd35ffd3b8b6e5Test

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