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المؤلفون: Marie-Anne Loriot, Nicolas Pallet, Céline Narjoz, S. Roueff, Clotilde Gaible
المصدر: Cancer Chemotherapy and Pharmacology. 88:1049-1053
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Dihydropyrimidine Dehydrogenase Deficiency, medicine.medical_treatment, Population, Toxicology, Gastroenterology, End stage renal disease, chemistry.chemical_compound, Renal Dialysis, Internal medicine, medicine, Dihydropyrimidine dehydrogenase, Humans, Mass Screening, False Positive Reactions, Pharmacology (medical), Prospective Studies, Uracil, education, Dihydrouracil Dehydrogenase (NADP), Dialysis, Pharmacology, education.field_of_study, business.industry, Dihydrouracil, Oncology, chemistry, Case-Control Studies, Kidney Failure, Chronic, DPYD, Hemodialysis, business, Pharmacogenetics, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d92d8bc9f1cc51096c2887fd7db3325Test
https://doi.org/10.1007/s00280-021-04354-7Test -
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المؤلفون: Humaid O. Al-Shamsi, Mohammed Algarni, Abdulraheem Alshangiti, Hamoud Al-Khallaf, Emad Tashkandi, Nedal Bukhari
المصدر: Clinics and Practice, Vol 11, Iss 62, Pp 467-471 (2021)
Clinics and Practice
Volume 11
Issue 3
Pages 62-471مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Medicine (General), Colorectal cancer, medicine.medical_treatment, Population, 030105 genetics & heredity, chemotherapy, Article, polymorphism, Capecitabine, 03 medical and health sciences, 0302 clinical medicine, DPYD, R5-920, Polymorphism (computer science), Internal medicine, 5-Fluorouuracil, medicine, Dihydropyrimidine dehydrogenase, education, Chemotherapy, education.field_of_study, business.industry, dihydropyrimidine dehydrogenase, General Medicine, Prodrug, medicine.disease, 030220 oncology & carcinogenesis, business, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd16c4b35746feb6490c3f54bb3a46fTest
https://www.mdpi.com/2039-7283/11/3/62Test -
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المؤلفون: Elisabetta Casalone, Rosanna Asselta, Elvezia Maria Paraboschi, Giovanni Cugliari, Elisa Giorgio, Alessia Russo, Diego Ardissino, Serena Aneli, Giovanni Birolo, Giuseppe Matullo, Cornelia Di Gaetano, Alessandra Allione, Stefano Duga
المصدر: Human Mutation. 42:272-289
مصطلحات موضوعية: medicine.medical_specialty, Population, Biology, genetic frequency database, 03 medical and health sciences, symbols.namesake, Exome Sequencing, Genetics, medicine, Humans, Italian population, Exome, whole-exome sequencing, education, genomic medicine, pathogenic variants, rare variants, Gene, Genetics (clinical), Exome sequencing, 030304 developmental biology, 0303 health sciences, education.field_of_study, 030305 genetics & heredity, Genetic Variation, Europe, Italy, Genetic structure, Mendelian inheritance, symbols, Medical genetics, DPYD
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b267731a667fc3ef34eea204ee5c24Test
https://doi.org/10.1002/humu.24156Test -
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المصدر: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 628-634 (2021)مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, medicine.medical_treatment, Population, Bioinformatics, 01 natural sciences, Targeted therapy, 03 medical and health sciences, Dihydropyrimidine dehydrogenase, medicine, Chemotherapy, education, lcsh:QH301-705.5, Exome sequencing, Cancer, education.field_of_study, Circulating tumor DNA, biology, business.industry, Whole exome sequencing, Single nucleotide polymorphisms, 030104 developmental biology, lcsh:Biology (General), Pharmacogenomics, biology.protein, DPYD, Original Article, General Agricultural and Biological Sciences, SLCO1B1, business, Pharmacogenetics, 010606 plant biology & botany
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e95133580b4b264eb19b6b25e5e054Test
http://europepmc.org/articles/PMC7783809Test -
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المؤلفون: Yitian Zhou, Volker M. Lauschke, Carolina Dagli Hernandez
المصدر: British Journal of Cancer
مصطلحات موضوعية: Cancer Research, Dihydropyrimidine Dehydrogenase Deficiency, Genotype, Population, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Exome Sequencing, Genetic variation, Cancer genomics, Ethnicity, Dihydropyrimidine dehydrogenase, Humans, Genetic variability, education, Cancer genetics, Genotyping, Dihydrouracil Dehydrogenase (NADP), Genetics, education.field_of_study, Whole Genome Sequencing, Thiopurine methyltransferase, Genetic Variation, Methyltransferases, 3. Good health, Benchmarking, Phenotype, Oncology, 030220 oncology & carcinogenesis, biology.protein, DPYD, Algorithms
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb56ffdfbf84f1667728b6ec4a6cd4fTest
https://doi.org/10.1038/s41416-020-01084-0Test -
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المؤلفون: Marcelo Garrido, Miguel Cordova-Delgado, María A Lavanderos, Gareth I. Owen, Yuwei Liao, Matías Muñoz-Medel, María Loreto Bravo, Luis A. Quiñones, Elisa Cumsille, Zhiguang Li, Alejandro H. Corvalan, Juan Francisco Miquel, Maria Rodriguez-Fernandez, Mauricio P. Pinto, Ricardo Armisen, Charlotte Hill, Ignacio N. Retamal
المصدر: BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)مصطلحات موضوعية: Male, Oncology, Platinums, Cancer Research, Organoplatinum Compounds, Leucovorin, Platinum Compounds, Predictive models, Gene Frequency, Antineoplastic Combined Chemotherapy Protocols, Odds Ratio, RC254-282, Glycine Hydroxymethyltransferase, education.field_of_study, biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Multidrug Resistance-Associated Protein 2, DNA-Binding Proteins, Toxicity, Female, Fluorouracil, Multidrug Resistance-Associated Proteins, medicine.medical_specialty, Genotype, Orotate Phosphoribosyltransferase, Orotidine-5'-Phosphate Decarboxylase, Population, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Multienzyme Complexes, Stomach Neoplasms, Internal medicine, Confidence Intervals, Genetics, medicine, Humans, education, Chemotherapy toxicity, Capecitabine, Dihydrouracil Dehydrogenase (NADP), Methylenetetrahydrofolate Reductase (NADPH2), Aged, Retrospective Studies, Xeroderma Pigmentosum Group D Protein, business.industry, Research, Case-control study, Fluoropyrimidines, Cancer, Endonucleases, Genes, p53, medicine.disease, Single nucleotide polymorphism, Nomograms, Regimen, Logistic Models, Pyrimidines, Glutathione S-Transferase pi, Case-Control Studies, Methylenetetrahydrofolate reductase, Quality of Life, biology.protein, DPYD, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfd59ac1910b74d4c301894d0fd29a8Test
https://doi.org/10.1186/s12885-021-08745-0Test -
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المؤلفون: Nan Lin, Michael J. Cavnar, Shulin Zhang, Kyle Zacholski, Frederick R. Ueland, Megan L. Hutchcraft, Catherine Sears, Elizabeth Belcher, Eric B. Durbin, John L. Villano, Jill M. Kolesar, Susanne M. Arnold
المصدر: Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4524, p 4524 (2021)مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Population, mercaptopurine, Article, Pharmacogenomic Variants, Internal medicine, medicine, cancer, 5-fluorouracil, education, RC254-282, irinotecan, pharmacogenomics, education.field_of_study, Thiopurine methyltransferase, biology, business.industry, real word, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, medicine.disease, Irinotecan, Pharmacogenomics, biology.protein, DPYD, business, Pharmacogenetics, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3781421edf0188ea73f6a18804307e2dTest
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المؤلفون: W. Timothy O'Brien, Olivia J. Veatch, Elissa J. Chesler, Karen L. Svenson, Xiaofeng Guo, Lin Zhang, Brendan T. Keenan, Raymond J. Galante, Jie Lian, Allan I. Pack, Gary A. Churchill
المصدر: Curr Biol
مصطلحات موضوعية: Genetics, Mice, Knockout, education.field_of_study, Haplotype, Population, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Mice, Haplotypes, Knockout mouse, Expression quantitative trait loci, Dihydropyrimidine dehydrogenase, beta-Alanine, Animals, DPYD, Allele, General Agricultural and Biological Sciences, education, Sleep, Gene, Dihydrouracil Dehydrogenase (NADP)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7cbce72dd29e5c2d1883d35e75d1c2Test
https://pubmed.ncbi.nlm.nih.gov/34653361Test -
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المؤلفون: Yitian Zhou, Volker M. Lauschke
المصدر: Human Genetics
مصطلحات موضوعية: 0303 health sciences, education.field_of_study, Thiopurine methyltransferase, biology, Population, CYP2C19, Bioinformatics, Human genetics, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Pharmacogenomics, Genetics, biology.protein, DPYD, education, Genotyping, Genetics (clinical), Pharmacogenetics, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925f1947fa22cd4e0a411b3765e07046Test
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المؤلفون: Stefano Fontana, Carlo R. Largiadèr, Dominic Schärer, Stefan Schürch, Robert B. Diasio, Seid Hamzic, Christos T. Nakas, Ursula Amstutz, Didier Meulendijks, Marc Wehrli, Steven M. Offer
المصدر: Hamzic, Seid; Schärer, Dominic; Offer, Steven M.; Meulendijks, Didier; Nakas, Christos; Diasio, Robert B; Fontana, Stefano; Wehrli, Marc; Schürch, Stefan; Amstutz, Ursula; Largiadèr, Carlo R. (2021). Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5-fluorouracil toxicity. British journal of clinical pharmacology, 87(8), pp. 3234-3243. Wiley-Blackwell 10.1111/bcp.14742 <http://dx.doi.org/10.1111/bcp.14742Test>
British Journal of Clinical Pharmacologyمصطلحات موضوعية: Linkage disequilibrium, haplotype, Drug-Related Side Effects and Adverse Reactions, Genotype, Population, 610 Medicine & health, Biology, chemotherapy, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, DPYD, 540 Chemistry, Dihydropyrimidine dehydrogenase, Humans, Pharmacology (medical), uracil, 030212 general & internal medicine, education, Dihydrouracil Dehydrogenase (NADP), pharmacogenetics, Pharmacology, education.field_of_study, dihydropyrimidine dehydrogenase, Haplotype, Dihydrouracil, Original Articles, Molecular biology, 5‐fluorouracil, chemistry, Haplotypes, 570 Life sciences, biology, Original Article, Fluorouracil, Pharmacogenetics
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e065a3410c6f5d8e92f10376d91f8964Test
