التفاصيل البيبلوغرافية
| العنوان: |
Accuracy and cost-effectiveness of dynamic contrast-enhanced CT in the characterisation of solitary pulmonary nodules-the SPUtNIk study |
| المؤلفون: |
Qureshi, NR, Rintoul, RC, Miles, KA, George, S, Harris, S, Madden, J, Cozens, K, Little, LA, Eichhorst, K, Jones, J, Moate, P, McClement, C, Pike, L, Sinclair, D, Wong, WL, Shekhdar, J, Eaton, R, Shah, A, Brindle, L, Peebles, C, Banerjee, A, Dizdarevic, S, Han, S, Poon, FW, Groves, AM, Kurban, L, Frew, AJ, Callister, ME, Crosbie, P, Gleeson, FV, Karunasaagarar, K, Kankam, O, Gilbert, FJ |
| المصدر: |
BMJ Open Respiratory Research , 3 (1) , Article e000156. (2016) |
| سنة النشر: |
2016 |
| مصطلحات موضوعية: |
Imaging/CT MRI etc, Lung Cancer, envir, eco |
| الوصف: |
INTRODUCTION: Solitary pulmonary nodules (SPNs) are common on CT. The most cost-effective investigation algorithm is still to be determined. Dynamic contrast-enhanced CT (DCE-CT) is an established diagnostic test not widely available in the UK currently. METHODS AND ANALYSIS: The SPUtNIk study will assess the diagnostic accuracy, clinical utility and cost-effectiveness of DCE-CT, alongside the current CT and 18-flurodeoxyglucose-positron emission tomography) ((18)FDG-PET)-CT nodule characterisation strategies in the National Health Service (NHS). Image acquisition and data analysis for (18)FDG-PET-CT and DCE-CT will follow a standardised protocol with central review of 10% to ensure quality assurance. Decision analytic modelling will assess the likely costs and health outcomes resulting from incorporation of DCE-CT into management strategies for patients with SPNs. ETHICS AND DISSEMINATION: Approval has been granted by the South West Research Ethics Committee. Ethics reference number 12/SW/0206. The results of the trial will be presented at national and international meetings and published in an Health Technology Assessment (HTA) Monograph and in peer-reviewed journals. TRIAL REGISTRATION NUMBER: ISRCTN30784948; Pre-results. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
http://discovery.ucl.ac.uk/1529793/1/Miles_e000156.full.pdfTest |
| الإتاحة: |
http://discovery.ucl.ac.uk/1529793/1/Miles_e000156.full.pdfTest |
| حقوق: |
undefined |
| رقم الانضمام: |
edsbas.CCB95EE2 |
| قاعدة البيانات: |
BASE |
