نتائج البحث - "Ketoconazole"

1

دورية أكاديمية

Physiologically Based Pharmacokinetic Modeling of Nilotinib for Drug‐Drug Interactions, Pediatric Patients, and Pregnancy and Lactation.

المؤلفون: Liu, Xiaomei I.¹, Leong, Ruby², Burckart, Gilbert J.² gilbert.burckart@fda.hhs.gov, Dallmann, André³

المصدر: Journal of Clinical Pharmacology. Mar2024, Vol. 64 Issue 3, p323-333. 11p.

مصطلحات موضوعية: *LACTATION, *KETOCONAZOLE, *NILOTINIB, *CHRONIC myeloid leukemia, *TIME, *COMPARATIVE studies, *DRUG interactions, *DESCRIPTIVE statistics, *RESEARCH funding, *PREDICTION models, *RIFAMPIN, *CHILDREN, *ADULTS, *PREGNANCY

2

دورية أكاديمية

Physiologically Based Pharmacokinetic Modeling of the Drug–Drug Interaction Between CYP3A4 Substrate Glasdegib and Moderate CYP3A4 Inducers in Lieu of a Clinical Study.

المؤلفون: Callegari, Ernesto¹ Ernesto.Callegari@pfizer.com, Tse, Susanna¹, Doran, Angela C.¹, Goosen, Theunis C.¹, Shaik, Naveed²

المصدر: Journal of Clinical Pharmacology. Jan2024, Vol. 64 Issue 1, p80-93. 14p.

مصطلحات موضوعية: *KETOCONAZOLE, *EFAVIRENZ, *IN vitro studies, *CYTOCHROME P-450, *SIMULATION methods in education, *HEDGEHOG signaling proteins, *DRUG interactions, *OXIDOREDUCTASES, *RIFAMPIN, *RECEIVER operating characteristic curves, *CHEMICAL inhibitors

3

دورية أكاديمية

Quantitative prediction of CYP3A‐mediated drug–drug interactions by correctly estimating fraction metabolized using human liver chimeric mice.

المؤلفون: Miyake, Taiji, Mochizuki, Tatsuki, Nakagawa, Toshito, Nakamura, Mikiko, Emoto, Chie, Komiyama, Natsuko, Hirabayashi, Manabu, Tsuruta, Satoshi, Shimojo, Tomofumi, Terao, Kimio, Tachibana, Tatsuhiko

المصدر: British Journal of Pharmacology; Apr2024, Vol. 181 Issue 7, p1091-1106, 16p

مصطلحات موضوعية: DRUG interactions, DRUG discovery, MICE, LIVER, KETOCONAZOLE, LIVER cells

4

دورية أكاديمية

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators.

المؤلفون: Marok, Fatima Zahra¹ (AUTHOR), Wojtyniak, Jan-Georg^1,2 (AUTHOR), Fuhr, Laura Maria¹ (AUTHOR), Selzer, Dominik¹ (AUTHOR), Schwab, Matthias^2,3,4 (AUTHOR), Weiss, Johanna^5,6 (AUTHOR), Haefeli, Walter Emil^5,6 (AUTHOR), Lehr, Thorsten¹ (AUTHOR) thorsten.lehr@mx.uni-saarland.de

المصدر: Pharmaceutics. Feb2023, Vol. 15 Issue 2, p679. 22p.

مصطلحات موضوعية: *DRUG interactions, *KETOCONAZOLE, *DRUG-food interactions, *ANTIFUNGAL agents, *METABOLITES, *PHARMACOKINETICS

النص الكامل

5

دورية أكاديمية

Prediction of drug–drug interactions between roflumilast and CYP3A4/1A2 perpetrators using a physiologically-based pharmacokinetic (PBPK) approach.

المؤلفون: Jia, Guangwei, Ren, Congcong, Wang, Hongyan, Fan, Caixia

المصدر: BMC Pharmacology & Toxicology; 1/2/2024, Vol. 25 Issue 1, p1-13, 13p

مصطلحات موضوعية: ITRACONAZOLE, DRUG interactions, PHARMACOKINETICS, CYTOCHROME P-450 CYP3A, KETOCONAZOLE, FORECASTING

النص الكامل

6

دورية أكاديمية

Analyzing Potential Intestinal Transporter Drug-Drug Interactions: Reevaluating Ticagrelor Interaction Studies

المؤلفون: Liu, Shuaibing, Sodhi, Jasleen K, Benet, Leslie Z

المصدر: Pharmaceutical Research. 38(10)

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/824025xcTest

View record in eScholarship

7

دورية أكاديمية

Challenging the Relevance of Unbound Tissue-to-Blood Partition Coefficient (Kpuu) on Prediction of Drug-Drug Interactions

المؤلفون: Sodhi, Jasleen K, Liu, Shuaibing, Benet, Leslie Z

المصدر: Pharmaceutical Research. 37(4)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Liver Disease, Digestive Diseases, Blood, Drug Interactions, Humans, Ketoconazole, Liver, Midazolam, Models, Chemical, Kp(uu), liver-to-blood partitioning, drug-drug interactions, well-stirred model, Kpuu, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3g8942snTest

View record in eScholarship

8

دورية أكاديمية

Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.

المؤلفون: Eisenmann, Eric D., Garrison, Dominique A., Talebi, Zahra, Jin, Yan, Silvaroli, Josie A., Kim, Jin-Gyu, Sparreboom, Alex, Savona, Michael R., Mims, Alice S., Baker, Sharyn D.

المصدر: Pharmaceutics; Apr2022, Vol. 14 Issue 4, pN.PAG-N.PAG, 16p

مصطلحات موضوعية: DRUG interactions, VENETOCLAX, CYTOCHROME P-450 CYP3A, HEMATOLOGIC malignancies, ANTIFUNGAL agents, KETOCONAZOLE, ITRACONAZOLE

النص الكامل

9

دورية أكاديمية

An insight on the nature of biochemical interactions between glycyrrhizin, myricetin and CYP3A4 isoform.

المؤلفون: Sabiu, Saheed, Idowu, Kehinde

المصدر: Journal of Food Biochemistry; Mar2022, Vol. 46 Issue 3, p1-12, 12p

مصطلحات موضوعية: CYTOCHROME P-450 CYP3A, MYRICETIN, DRUG interactions, DIETARY supplements, CARDIOLOGICAL manifestations of general diseases, KETOCONAZOLE

10

دورية أكاديمية

Perpetrator Characteristics of Azole Antifungal Drugs on Three Oral Factor Xa Inhibitors Administered as a Microdosed Cocktail.

المؤلفون: Rohr, Brit Silja, Foerster, Kathrin Isabelle, Blank, Antje, Burhenne, Jürgen, Mahmoudi, Mazyar, Haefeli, Walter Emil, Mikus, Gerd

المصدر: Clinical Pharmacokinetics; Jan2022, Vol. 61 Issue 1, p97-109, 13p

مصطلحات موضوعية: ANTIFUNGAL agents, ORAL medication, AZOLES, DRUG interactions, COCKTAILS, KETOCONAZOLE, CYTOCHROME P-450

تنقيح النتائج