نتائج البحث - "Wyatt W, Yue"

1

دورية أكاديمية

A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

المؤلفون: Gabriele Bassi, Nicholas Favalli, Miriam Vuk, Marco Catalano, Adriano Martinelli, Anika Trenner, Antonio Porro, Su Yang, Chuin Lean Tham, Mustafa Moroglu, Wyatt W. Yue, Stuart J. Conway, Peter K. Vogt, Alessandro A. Sartori, Jörg Scheuermann, Dario Neri

المصدر: Advanced Science, Vol 7, Iss 22, Pp n/a-n/a (2020)

مصطلحات موضوعية: Human alpha‐aminoadipic semialdehyde synthase (AASS), affinity maturation, cyclic‐AMP response element binding protein (CREBBP), DNA‐encoded chemical libraries (DEL), drug discovery, encoded self‐assembling chemical libraries (ESAC), Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2198-3844Test

الوصول الحر: https://doaj.org/article/6523af672d2b411ba7e7080f84e45492Test

View record in DOAJ

النص الكامل

2

Dipeptidyl peptidase 11 (PgDPP11); A Target Enabling Package

المؤلفون: Catherine Tham, Jesse Coker, William Foster, Tobias Krojer, Lizbe Koekomer, Yuko Ohara-Nemoto, Takayuki K. Nemoto, Wyatt W. Yue, Frank von Delft, Gustavo Arruda Bezerra

مصطلحات موضوعية: Protein, Drug Discovery, Target, Periodontitis, Inflammation, Alzheimer's disease, Type 2 diabetes, Porphyromonas gingivalis

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://zenodo.org/record/6282253Test; https://doi.org/10.5281/zenodo.6282253Test; oai:zenodo.org:6282253

الإتاحة: https://doi.org/10.5281/zenodo.6282253Test
https://doi.org/10.5281/zenodo.6281991Test
https://zenodo.org/record/6282253Test

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3

4′-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function

المؤلفون: Wyatt W. Yue, Alain Martelli, Theresa Towle, Christine Bulawa, Joseph F. Nabhan, Renea Gooch, Xidong Feng, Tiffany Ma, Nicholas G. Fox, Jaimeen D. Majmudar

المصدر: MedChemComm. 10:209-220

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a55720aed23cd65b2fdf1a60e5461cfTest
https://doi.org/10.1039/c8md00489gTest

4

Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package

المؤلفون: Gustavo A. Bezerra, William R. Foster, Henry J. Bailey, Kevin G. Hicks, Sven W. Sauer, Bianca Dimitrov, Thomas J. McCorvie, Jurgen G. Okum, Jared Rutter, Stefan Kӧlker, Wyatt W. Yue

مصطلحات موضوعية: Protein, Target Enabling Package, Disease, Structure, Structural Genomics, Drug Discovery, Orphan Disease, Drug Target, Chemical Biology, Probe, Structure Discovery, Metabolic Diseases, DHTKD1, Dehydrogenase E1 and transketolase domain-containing protein 1

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://zenodo.org/communities/sgctepsTest; https://zenodo.org/record/4469332Test; https://doi.org/10.5281/zenodo.4469332Test; oai:zenodo.org:4469332

الإتاحة: https://doi.org/10.5281/zenodo.4469332Test
https://doi.org/10.5281/zenodo.4428229Test
https://zenodo.org/record/4469332Test

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5

Fibrinogen-like globe domain of human Tenascin-C (hFBG-C); A Target Enabling Package

المؤلفون: Jesse A. Coker, Anna Marzeda, Anja Schwenzer, Brian D. Marsden, Kim S. Midwood, Wyatt W. Yue

مصطلحات موضوعية: Protein, Target Enabling Package, Disease, Structure, Structural Genomics, Drug Discovery, Orphan Disease, Drug Target, Chemical Biology, Probe, Structure Discovery, Inflammation, Inflammatory Disorders, TNC, Tenascin-C

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://zenodo.org/record/4429107Test; https://doi.org/10.5281/zenodo.4429107Test; oai:zenodo.org:4429107

الإتاحة: https://doi.org/10.5281/zenodo.4429107Test
https://doi.org/10.5281/zenodo.4429073Test
https://zenodo.org/record/4429107Test

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6

Human Galatose-1-phosphate Uridylyltransferase (GALT), Galactokinase 1 (GALK1); A Target Enabling Package

المؤلفون: Gustavo Arruda Bezerra, Sabrina MacKinnon, Thomas McCorvie, Minghao Zhang, Manshu Tang, William Foster, Michael Fairhead, Anthony Tumber, Claire Strain-Damerell, Jolanta Kopec, Fiona Fitzpatrick, Frank Whitby, Christopher P. Hill, Kent Lai, Wyatt W. Yue

مصطلحات موضوعية: Protein, Target Enabling Package, Disease, Structure, Cancer, Neuro, Neurological Genetic Disorders, Metabolic Disease, Oncology, Infectious Disease, Malaria, Structural Genomics, Drug Discovery, Orphan Disease, Drug Target, Chemical Biology, Probe, Structure Discovery, GALT, GALK1, Galactosemia

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://zenodo.org/communities/sgctepsTest; https://zenodo.org/record/3250158Test; https://doi.org/10.5281/zenodo.3250158Test; oai:zenodo.org:3250158

الإتاحة: https://doi.org/10.5281/zenodo.3250158Test
https://doi.org/10.5281/zenodo.3234909Test
https://zenodo.org/record/3250158Test

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7

Human 5'-Aminolevulinate Synthase, Erythroid-Specific (ALAS2); A Target Enabling Package

المؤلفون: Gustavo A. Bezerra, Henry J. Bailey, Jason R. Marcero, William R. Foster, Elzbieta Rembeza, Harry A. Dailey, Jr., Wyatt W. Yue

مصطلحات موضوعية: Protein, Target Enabling Package, Disease, Structure, Cancer, Neuropsychiatry, Neuro, Neurological Genetic Disorders, Metabolic Diseases, Oncology, Infectious Disease, Malaria, Structural Genomics, Drug Discovery, Orphan Disease, Drug Target, Chemical Biology, Probe, Structure Discovery, ALAS2

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://zenodo.org/communities/sgctepsTest; https://zenodo.org/record/3245203Test; https://doi.org/10.5281/zenodo.3245203Test; oai:zenodo.org:3245203

الإتاحة: https://doi.org/10.5281/zenodo.3245203Test
https://doi.org/10.5281/zenodo.3245202Test
https://zenodo.org/record/3245203Test

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8

Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation

المؤلفون: Wyatt W. Yue, Hans van Bokhoven, Walinka van Tol, Moniek Riemersma, Jolanta Kopec, D. Sean Froese, Hiroshi Manya, Ewa Swiezewska, Dirk Lefeber, Thijn R. Brummelkamp, T. Krojer, Monique van Scherpenzeel, Lucas T. Jae, Angel Ashikov, Frank von Delft, Tamao Endo, Anna Buczkowska, Udo F. H. Engelke, Marco Tessari

المساهمون: Klinische Genetica, RS: CARIM - R2 - Cardiac function and failure

المصدر: Chemistry & Biology, 22, 12, pp. 1643-52
Chemistry & Biology, 22, 1643-52
Chemistry & Biology, 22(12), 1643-1652. Elsevier Inc.

مصطلحات موضوعية: Glycan, Glycosylation, Clinical Biochemistry, Biology, Crystallography, X-Ray, Nucleotide sugar, Ribitol, Biochemistry, Gene Knockout Techniques, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ribose, Drug Discovery, Dystroglycan, Humans, Transferase, Choline-Phosphate Cytidylyltransferase, Disorders of movement Radboud Institute for Molecular Life Sciences [Radboudumc 3], Dystroglycans, Molecular Biology, Cells, Cultured, 030304 developmental biology, Pharmacology, 0303 health sciences, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], ATP synthase, General Medicine, Fibroblasts, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Nucleotidyltransferases, carbohydrates (lipids), chemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f6dd8c1c982f85e43feff77e40e356Test

9

Human Hydroxyacid Oxidase (HAO1); A Target Enabling Package

المؤلفون: Sabrina MacKinnon, Gustavo Arruda Bezerra, Tobias Krojer, Anthony R. Bradley, Romain Talon, Jose Brandao-Neto, Alice Douangamath, Udo Oppermann, Frank von Delft, Paul E. Brennan, Wyatt W. Yue

مصطلحات موضوعية: Protein, Target Enabling Package, Disease, Structure, Cancer, Neuropsychiatry, Neuro, Neurological Genetic Disorders, Metabolic Diseases, Oncology, Infectious Disease, Malaria, Structural Genomics, Drug Discovery, Orphan Disease, Drug Target, Chemical Biology, Probe, Structure Discovery, HAO1

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://openlabnotebooks.org/category/disease-foundation/primary-hyperoxaluriaTest/; https://zenodo.org/communities/sgc-opennotebookTest; https://zenodo.org/communities/sgctepsTest; https://zenodo.org/record/1344541Test; https://doi.org/10.5281/zenodo.1344541Test; oai:zenodo.org:1344541

الإتاحة: https://doi.org/10.5281/zenodo.1344541Test
https://doi.org/10.5281/zenodo.1342617Test
https://zenodo.org/record/1344541Test

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10

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package

المؤلفون: Jola Kopec, Izabella Pena, Elzbieta Rembeza, Mark McLaughlin, Oleg Fedorov, Claire Strain-Damerell, Solenne Goubin, Sabrina MacKinnon, Nicola Burgess-Brown, Paul Brennan, Alex MacKenzie, Paulo Arruda, Wyatt W. Yue

مصطلحات موضوعية: protein, target enabling package, disease, structure, cancer, neuropsychiatry, neuro, neurological genetic disorders, metabolic diseases, oncology, infectious disease, malaria, structural genomics, drug discovery, orphan disease, drug target, chemical biology, chemical probe, structure discovery, AASS

العلاقة: info:eu-repo/grantAgreement/WT/Molecular Basis of Cell Function/106169/; https://www.thesgc.org/tepTest; https://zenodo.org/communities/sgctepsTest; https://zenodo.org/record/2653517Test; https://doi.org/10.5281/zenodo.2653517Test; oai:zenodo.org:2653517

الإتاحة: https://doi.org/10.5281/zenodo.2653517Test
https://doi.org/10.5281/zenodo.1219674Test
https://zenodo.org/record/2653517Test

View record in BASE

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