المؤلفون: Ravasio R., Ceccacci E., Nicosia L., Hosseini A., Rossi P. L., Barozzi I., Fornasari L., Zuffo R. D., Valente S., Fioravanti R., Mercurio C., Varasi M., Mattevi A., Mai A., Pavesi G., Bonaldi T., Minucci S.

المساهمون: Ravasio, R., Ceccacci, E., Nicosia, L., Hosseini, A., Rossi, P. L., Barozzi, I., Fornasari, L., Zuffo, R. D., Valente, S., Fioravanti, R., Mercurio, C., Varasi, M., Mattevi, A., Mai, A., Pavesi, G., Bonaldi, T., Minucci, S.

مصطلحات موضوعية: drug design, epigenetics, cancer

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32284990; info:eu-repo/semantics/altIdentifier/wos/WOS:000525751400003; volume:6; issue:15; firstpage:eaax2746; journal:SCIENCE ADVANCES; http://hdl.handle.net/11571/1341600Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85083269142; https://advances.sciencemag.org/content/6/15/eaax2746Test

الإتاحة: https://doi.org/10.1126/sciadv.aax2746Test
http://hdl.handle.net/11571/1341600Test
https://advances.sciencemag.org/content/6/15/eaax2746Test

المؤلفون: Valente S, Rodriguez V, Mercurio C, Vianello P, Saponara B, Cirilli R, Labella D, Marrocco B, Ruoppolo G, Botrugno OA, Dessanti P, Minucci S, Varasi M, Mai A., CIOSSANI, GIUSEPPE, MATTEVI, ANDREA

المساهمون: Valente, S, Rodriguez, V, Mercurio, C, Vianello, P, Saponara, B, Cirilli, R, Ciossani, Giuseppe, Labella, D, Marrocco, B, Ruoppolo, G, Botrugno, Oa, Dessanti, P, Minucci, S, Mattevi, Andrea, Varasi, M, Mai, A.

مصطلحات موضوعية: Drug design, epigenetic

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/The pure four diastereomers (1; info:eu-repo/semantics/altIdentifier/wos/000349652000012; volume:6; firstpage:173; lastpage:177; numberofpages:5; journal:ACS MEDICINAL CHEMISTRY LETTERS; http://hdl.handle.net/11571/1094195Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84922867052

الإتاحة: https://doi.org/10.1021/ml500424zTest
http://hdl.handle.net/11571/1094195Test

المؤلفون: Angela Santoni, Alessandra Soriani, Romano Silvestri, Bruno Maresca, Cristiano Ferlini, Valerio Gatti, Ruoli Bai, Ciro Mercurio, Willeke Rensen, Antonio Lavecchia, Giulio Dondio, Francesco Piscitelli, Ernest Hamel, Alessio Bolognesi, Maria Luisa Iannitto, Mario Varasi, Patrizia Lavia, Andrea Brancale, Ilaria Granata, Antonio Coluccia, Giuseppe La Regina, Amalia Porta, Ettore Novellino, Marisa Mariani

المساهمون: La Regina, G., Bai, R., Rensen, W., Coluccia, A., Piscitelli, F., Gatti, V., Bolognesi, A., Lavecchia, Antonio, Granata, I., Porta, A., Maresca, B., Soriani, A., Iannitto, M. L., Mariani, M., Santoni, A., Brancale, A., Ferlini, C., Dondio, G., Varasi, M., Mercurio, C., Hamel, E., Lavia, P., Novellino, Ettore, Silvestri, R.

المصدر: Journal of medicinal chemistry 54 (2011): 8394–8406. doi:10.1021/jm2012886
info:cnr-pdr/source/autori:La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio MG, Varasi M, Mercurio C, Hamel E, Lavia P, Novellino E, Silvestri R./titolo:Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability/doi:10.1021%2Fjm2012886/rivista:Journal of medicinal chemistry/anno:2011/pagina_da:8394/pagina_a:8406/intervallo_pagine:8394–8406/volume:54

مصطلحات موضوعية: Male, Indoles, Administration, Oral, Pharmacology, Docking, Mice, chemistry.chemical_compound, Drug Discovery, Caspase 3, Cell Cycle, Tubulin Modulators, Vinblastine, Paclitaxel, Biochemistry, Injections, Intravenous, Microsomes, Liver, Molecular Medicine, Cancer Cell, medicine.drug, Biological Availability, Mice, Nude, Antineoplastic Agents, Microtubule, Thiophenes, In Vitro Techniques, Article, Cell Line, Anticancer Agent, Structure-Activity Relationship, Pharmacokinetics, Cell Line, Tumor, Breast Cancer, medicine, Animals, Humans, Pyrroles, Furans, Cell Proliferation, Combretastatin, Cell growth, Antimitotic Drug, Bioavailability, Solubility, chemistry, Drug Resistance, Neoplasm, Apoptosis, Cell culture, Indole, Drug Design, Drug Screening Assays, Antitumor, Colchicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982e1c6a1e422676ace27810974272c2Test
http://hdl.handle.net/11588/415081Test