المؤلفون: Parker, Christopher, Chambers, Adam C, Flanagan, Dustin J, Ho, Jasmine Wing Yu, Collard, Tracey J, Ngo, Greg, Baird, Duncan M, Timms, Penny, Morgan, Rhys G., Sansom, Owen J, Williams, Ann C

المصدر: Parker , C , Chambers , A C , Flanagan , D J , Ho , J W Y , Collard , T J , Ngo , G , Baird , D M , Timms , P , Morgan , R G , Sansom , O J & Williams , A C 2022 , ' BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination ' , DNA repair , vol. 115 , 103331 . https://doi.org/10.1016Test/j.dnarep.2022.103331

مصطلحات موضوعية: Animals, Cell Line, Tumor, Cisplatin/therapeutic use, Colorectal Neoplasms/drug therapy, DNA Damage, Homologous Recombination, Humans, Mice

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016Test/j.dnarep.2022.103331
https://hdl.handle.net/1983/a562c74f-57b8-47be-b70e-d9e1984cfa3dTest
https://research-information.bris.ac.uk/en/publications/a562c74f-57b8-47be-b70e-d9e1984cfa3dTest
https://research-information.bris.ac.uk/ws/files/339239049/1_s2.0_S1568786422000647_main.pdfTest

المؤلفون: Myant, Kevin B., Cammareri, Patrizia, Hodder, Michael C., Wills, Jimi, Von Kriegsheim, Alexander, Győrffy, Balázs, Rashid, Mamun, Polo, Simona, Maspero, Elena, Vaughan, Lynsey, Gurung, Basanta, Barry, Evan, Malliri, Angeliki, Camargo, Fernando, Adams, David J., Iavarone, Antonio, Lasorella, Anna, Sansom, Owen J.

المصدر: Myant, K B, Cammareri, P, C Hodder, M, Wills, J, Von Kriegsheim, A, Győrffy, B, Rashid, M, Polo, S, Maspero, E, Vaughan, L, Gurung, B, Barry, E, Malliri, A, Camargo, F, J Adams, D, Iavarone, A, Lasorella, A & J Sansom, O 2017, ' HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation ', EMBO Molecular Medicine, vol. 9, no. 2, pp. 181-197 . https://doi.org/10.15252/emmm.201606684Test
Myant, K B, Cammareri, P, Hodder, M C, Wills, J, Von Kriegsheim, A, Győrffy, B, Rashid, M, Polo, S, Maspero, E, Vaughan, L, Gurung, B, Barry, E, Malliri, A, Camargo, F, Adams, D J, Iavarone, A, Lasorella, A & Sansom, O J 2017, ' HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation ', EMBO Molecular Medicine, pp. 181-197 . https://doi.org/10.15252/emmm.201606684Test

مصطلحات موضوعية: COLORECTAL CANCER, HUWE1, MCL1, Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, MYC, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b56505d4183423cc974678b93d60c37dTest
https://eprints.gla.ac.uk/138350/1/138350.pdfTest

المؤلفون: Toft, Neil J, Sansom, Owen J, Brookes, Roger A, Arends, Mark J, Wood, Michelle, Margison, Geoffrey P, Winton, Douglas J, Clarke, Alan R

المساهمون: Department of Pathology, University of Edinburgh, Edinburgh EH8 9AG, UK.

مصطلحات موضوعية: Animals, Antineoplastic Agents, Alkylating, Apoptosis, Biotransformation, Cisplatin, Cytochrome P-450 Enzyme System, DNA Damage, Dacarbazine, Enzyme Inhibitors, Guanine, Intestine, Small, Methylnitrosourea, Mice, Mutation, O(6)-Methylguanine-DNA Methyltransferase

العلاقة: In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine. 2000, 21 (4):593-8 Carcinogenesis; http://hdl.handle.net/10541/86189Test; Carcinogenesis

الإتاحة: https://doi.org/10.1093/carcin/21.4.593Test
http://hdl.handle.net/10541/86189Test

المؤلفون: Croft, Daniel R, Crighton, Diane, Samuel, Michael S, Lourenco, Filipe C, Munro, June, Wood, Jenifer, Bensaad, Karim, Vousden, Karen H, Sansom, Owen J, Ryan, Kevin M, Olson, Michael F

المصدر: Cell Research; Apr2011, Vol. 21 Issue 4, p666-682, 17p

مصطلحات موضوعية: CYTOSKELETON, CELL cycle, DNA damage, APOPTOSIS, CYTOLOGY

المؤلفون: Hay, Trevor, Patrick, Teresa, Winton, Douglas, Sansom, Owen J., Clarke, Alan R.

المصدر: Oncogene; 5/26/2005, Vol. 24 Issue 23, p3842-3846, 5p

مصطلحات موضوعية: STEM cells, APOPTOSIS, BREAST cancer, GENETIC mutation, LIQUID oxygen, CELL death

المؤلفون: Marquez, Nuria, Chappell, Sally C, Sansom, Owen J, Clarke, Alan R, Court, Jon, Errington, Rachel J, Smith, Paul J

المصدر: Oncogene; 10/23/2003, Vol. 22 Issue 48, p7642-7648, 7p

مصطلحات موضوعية: DNA damage, CELL cycle, FIBROBLASTS, BIOCHEMICAL genetics, GENETIC mutation, MSH2 gene

المؤلفون: Sansom, Owen J.¹, Bishop, Stefan M.¹, Court, Helen¹, Dudley, Sandra², Liskay, R. Michael², Clarke, Alan R.¹ clarkear@cf.ac.uk

المصدر: DNA Repair. Sep2003, Vol. 2 Issue 9, p1029. 11p.

مصطلحات موضوعية: *PROTEINS, *APOPTOSIS, *GENES, *DNA damage, *BIOMOLECULES, *PMS genes

المؤلفون: Strathdee, Gordon, Sansom, Owen J, Sim, Alyson, Clarke, Alan R, Brown, Robert

المصدر: Oncogene. 4/5/2001, Vol. 20 Issue 15, p1923. 5p.

مصطلحات موضوعية: *DNA damage, *CELL cycle, *POLYPLOIDY, *P53 antioncogene

المؤلفون: Ritschka, Birgit^1,2, Storer, Mekayla^1,2,3, Mas, Alba^1,2, Heinzmann, Florian^4,5, Ortells, Mari Carmen^1,2, Morton, Jennifer P.^6,7, Sansom, Owen J.^6,7, Zender, Lars^4,5,8, Keyes, William M.^1,2,9 bill.keyes@igbmc.fr

المصدر: Genes & Development. Jan2017, Vol. 31 Issue 2, p172-183. 12p.

مصطلحات موضوعية: *MATERIAL plasticity, *TISSUE remodeling, *CELL cycle, *DNA damage, *ONCOGENES

المؤلفون: Cheung, Eric C.¹, Lee, Pearl¹, Ceteci, Fatih¹, Nixon, Colin¹, Blyth, Karen¹, Sansom, Owen J.¹, Vousden, Karen H.¹ k.vousden@beatson.gla.ac.uk

المصدر: Genes & Development. Jan2016, Vol. 30 Issue 1, p52-63. 12p.

مصطلحات موضوعية: *REACTIVE oxygen species, *WNT genes, *APOPTOSIS, *DNA damage, *CANCER treatment, *LABORATORY mice