دورية أكاديمية
Respiratory disorders of post-COVID-19 syndrome
| العنوان: | Respiratory disorders of post-COVID-19 syndrome |
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| المؤلفون: | Igor V. Leshchenko, Natalia A. Esaulova, Tatyana V. Glushkova, Sergey N. Skornyakov |
| المصدر: | Терапевтический архив, Vol 95, Iss 3, Pp 203-209 (2023) |
| بيانات النشر: | "Consilium Medicum" Publishing house, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | post-covid-19 syndrome, respiratory disorders, virus-induced bronchoobstructive syndrome, dlco, Medicine |
| الوصف: | Aim. Assess the functional state of trespiratory system and effectiveness of therapeutic tactics for broncho-obstructive syndrome (BOS) in patients in the post-COVID period. Materials and methods. A two-center cohort prospective study included 10 456 and 89 patients, respectively. A comprehensive assessment of the respiratory system included clinical, laboratory and functional data, spirometry, body plethysmography, and a study of diffusive capacity of the lungs (DLCO). Therapy consisted of budesonide suspension or fixed combination beclomethasone dipropionate/formoterol (EMD BDP/FORM). Results. The frequency of BOS in the cohort was 72% (7497 patients). In 13% (n=974) of cases, bronchial asthma was diagnosed for the first time, in 4.4% (n=328) chronic obstructive pulmonary disease. Risk factors for the development and decrease in DLCO in the post-COVID period were identified. In the group of complex instrumental examination of lung function, the absence of violations of spirometric data and indicators determined by body plethysmography was determined. Conclusion. Risk factors for BOS in post-COVID period are atopy, a history of frequent acute respiratory infections, smoking, blood eosinophilia, moderate and severe forms of COVID-19. The advantage of a fixed combination of EMD BDP/FORM in MART mode compared with nebulized suspension budesonide + solution of salbutamol in treatment of BOS was shown. Risk factors for DLCO disorders were established: severe COVID-19, hospitalization in the intensive care unit, the need for additional oxygen therapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 0040-3660 2309-5342 00403660 |
| العلاقة: | https://ter-arkhiv.ru/0040-3660/article/viewFile/340913/118439Test; https://doaj.org/toc/0040-3660Test; https://doaj.org/toc/2309-5342Test |
| DOI: | 10.26442/00403660.2023.03.202072 |
| الوصول الحر: | https://doaj.org/article/7943c5c253e24219a38a8167bceea307Test |
| رقم الانضمام: | edsdoj.7943c5c253e24219a38a8167bceea307 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00403660 23095342 |
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| DOI: | 10.26442/00403660.2023.03.202072 |