دورية أكاديمية

Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial.

التفاصيل البيبلوغرافية
العنوان: Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial.
المؤلفون: Rustin, Gordon J. S.1 (AUTHOR), van der Burg, Maria E. L.2 (AUTHOR), Griffin, Clare L.3 (AUTHOR), Guthrie, David4 (AUTHOR), Lamont, Alan5 (AUTHOR), Jayson, Gordon C.6,7 (AUTHOR), Kristensen, Gunnar8 (AUTHOR), Mediola, César9 (AUTHOR), Coens, Corneel10 (AUTHOR), Qian, Wendi3 (AUTHOR), Parmar, Mahesh K. B.3 (AUTHOR), Swart, Ann Marie3 (AUTHOR) ams@ctu.mrc.ac.uk
المصدر: Lancet. 10/2/2010, Vol. 376 Issue 9747, p1155-1163. 9p. 1 Diagram, 4 Charts, 2 Graphs.
مصطلحات موضوعية: OVARIAN cancer, CANCER treatment, CANCER in women, DISEASE remission, CANCER chemotherapy, CANCER relapse, RANDOMIZED controlled trials
مستخلص: The article discusses a study which investigated the benefits of early treatment of ovarian cancer on the basis of increased CA125 concentrations compared with delayed treatment on the basis of clinical recurrence. Involved in the randomised trial were 1,442 women with ovarian cancer in complete remission following first-line platinum-based chemotherapy. CA12 results were monitored by coordinating centres. The authors found no significant evidence of a difference in overall survival between early and delayed treatment.
قاعدة البيانات: Business Source Index
الوصف
تدمد:01406736
DOI:10.1016/S0140-6736(10)61268-8