Deconstructing Syndemics: The Many Layers of Clustering Multi-Comorbidities in People Living with HIV
| العنوان: | Deconstructing Syndemics: The Many Layers of Clustering Multi-Comorbidities in People Living with HIV |
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| المؤلفون: | Anya Snyder, Fassil Ketema, Emmanuel Peprah, Elisabet Caler |
| المصدر: | International Journal of Environmental Research and Public Health Volume 17 Issue 13 International Journal of Environmental Research and Public Health, Vol 17, Iss 4704, p 4704 (2020) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Health, Toxicology and Mutagenesis, Psychological intervention, Human immunodeficiency virus (HIV), lcsh:Medicine, HIV Infections, communicable diseases, Comorbidity, Disease, 030204 cardiovascular system & hematology, medicine.disease_cause, Article, 03 medical and health sciences, Health problems, 0302 clinical medicine, Syndemic, cardiovascular disease, Environmental health, medicine, Cluster Analysis, Humans, 030212 general & internal medicine, Child, Epidemics, Cluster analysis, skin and connective tissue diseases, sleep disorder, lung diseases, business.industry, Public health, lcsh:R, public health, Public Health, Environmental and Occupational Health, HIV, virus diseases, Syndemics, medicine.disease, non-communicable diseases, sense organs, business, health disparity, low and middle-income countries |
| الوصف: | The HIV epidemic has dramatically changed over the past 30 years there are now fewer newly infected people (especially children), fewer AIDS-related deaths, and more people with HIV (PWH) receiving treatment. However, the HIV epidemic is far from over. Despite the tremendous advances in anti-retroviral therapies (ART) and the implementation of ART regimens, HIV incidence (number of new infections over a defined period of time) and prevalence (the burden of HIV infection) in certain regions of the world and socio-economic groups are still on the rise. HIV continues to disproportionally affect highly marginalized populations that constitute higher-risk and stigmatized groups, underserved and/or neglected populations. In addition, it is not uncommon for PWH to suffer enhanced debilitating conditions resulting from the synergistic interactions of both communicable diseases (CDs) and non-communicable diseases (NCDs). While research utilizing only a comorbidities framework has advanced our understanding of the biological settings of the co-occurring conditions from a molecular and mechanistic view, harmful interactions between comorbidities are often overlooked, particularly under adverse socio-economical and behavioral circumstances, likely prompting disease clustering in PWH. Synergistic epidemics (syndemics) research aims to capture these understudied interactions: the mainly non-biological aspects that are central to interpret disease clustering in the comorbidities/multi-morbidities only framework. Connecting population-level clustering of social and health problems through syndemic interventions has proved to be a critical knowledge gap that will need to be addressed in order to improve prevention and care strategies and bring us a step closer to ending the HIV epidemic. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1660-4601 |
| DOI: | 10.3390/ijerph17134704 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92551fcefb0852e4a6bbf78ba368ce5eTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....92551fcefb0852e4a6bbf78ba368ce5e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16604601 |
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| DOI: | 10.3390/ijerph17134704 |