دورية أكاديمية

Effect of Radial Extracorporeal Shock Wave Combined With Ultrashort Wave Diathermy on Fibrosis and Contracture of Muscle.

التفاصيل البيبلوغرافية
العنوان: Effect of Radial Extracorporeal Shock Wave Combined With Ultrashort Wave Diathermy on Fibrosis and Contracture of Muscle.
المؤلفون: Peng-Peng Huang1, Quan-Bing Zhang1, Yun Zhou1, A-Ying Liu1, Feng Wang2, Qi-Yu Xu1, Fan Yang1
المصدر: American Journal of Physical Medicine & Rehabilitation. Jul2021, Vol. 100 Issue 7, p643-650. 8p.
مصطلحات موضوعية: *DIATHERMY, *COLLAGEN, *TRANSFORMING growth factors-beta, *CONTRACTURE (Pathology), *SKELETAL muscle, *RANGE of motion of joints, *ANIMAL experimentation, *CONVALESCENCE, *FIBROSIS, *RABBITS, *ANKYLOSIS, *ULTRASONIC therapy, *COMBINED modality therapy, *HYPOXEMIA
مستخلص: Objective: The purpose of this study was to examine the intervention effect of radial extracorporeal shock wave combined with ultrashort wave diathermy on immobilization-induced fibrosis and contracture of muscle. Design: The groups included male rabbits for the group (control group). To cause joint contracture, rabbits underwent plaster fixation of a left knee joint at full extension. After immobilization for 4 wks, all rabbits were randomly divided into five groups: model group, natural recovery group, radial extracorporeal shock wave treatment group, ultrashort wave diathermy group, and radial extracorporeal shock wave combined with ultrashort wave diathermy group. All intervention effects were assessed by evaluating the cross-sectional area and the collagen deposition of muscle, the knee joint range of motion and the protein levels for transforming growth factor β1 and hypoxia-inducible factor 1α. Results: The combined treatment group got the best recovery of the knee joint function. The combined treatment was more effective than radial extracorporeal shock wave or ultrashort wave diathermy alone against the fibrosis and contracture of muscle, as well as the overexpression of transforming growth factor β1 and hypoxia-inducible factor 1α. Conclusions: Radial extracorporeal shock wave combined with ultrashort wave diathermy was effective in alleviating immobilization- induced contracture and fibrosis of muscle, as well as reducing the molecular manifestations of muscle fibrosis. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:08949115
DOI:10.1097/PHM.0000000000001599